FGR proto-oncogene, Src family tyrosine kinase

mammalian protein found in Homo sapiens

Wikidata entity: Q21097222



P682 biological process ... Q189092 (cell migration) cell migration
P682 biological process ... Q210861 (cell differentiation) cell differentiation
P682 biological process ... Q242736 (phosphorylation) phosphorylation
P682 biological process ... Q7251493 (protein phosphorylation) protein phosphorylation
P682 biological process ... Q14330982 (positive regulation of phosphatidylinositol 3-kinase signaling) positive regulation of phosphatidylinositol 3-kinase signaling
P682 biological process ... Q14330986 (peptidyl-tyrosine phosphorylation) peptidyl-tyrosine phosphorylation
P682 biological process ... Q14599693 (bone mineralization) bone mineralization
P682 biological process ... Q14758919 (positive regulation of cell migration) positive regulation of cell migration
P682 biological process ... Q14762273 (positive regulation of phosphatidylinositol 3-kinase activity) positive regulation of phosphatidylinositol 3-kinase activity
P682 biological process ... Q14818120 (regulation of cell population proliferation) regulation of cell population proliferation
P682 biological process ... Q14819462 (regulation of cell shape) regulation of cell shape
P682 biological process ... Q428253 (innate immune response) innate immune response
P682 biological process ... Q3630494 (protein autophosphorylation) protein autophosphorylation
P682 biological process ... Q14863362 (transmembrane receptor protein tyrosine kinase signaling pathway) transmembrane receptor protein tyrosine kinase signaling pathway
P682 biological process ... Q14863968 (Fc-gamma receptor signaling pathway involved in phagocytosis) Fc-gamma receptor signaling pathway involved in phagocytosis
P682 biological process ... Q14864563 (defense response to Gram-positive bacterium) defense response to Gram-positive bacterium
P682 biological process ... Q14864931 (response to virus) response to virus
P682 biological process ... Q14865282 (regulation of protein kinase activity) regulation of protein kinase activity
P682 biological process ... Q14873943 (integrin-mediated signaling pathway) integrin-mediated signaling pathway
P682 biological process ... Q14877685 (skeletal system morphogenesis) skeletal system morphogenesis
P682 biological process ... Q14907328 (positive regulation of mast cell degranulation) positive regulation of mast cell degranulation
P682 biological process ... Q14907333 (regulation of phagocytosis) regulation of phagocytosis
P682 biological process ... Q14911651 (neutrophil degranulation) neutrophil degranulation
P682 biological process ... Q14911811 (immune response-regulating cell surface receptor signaling pathway) immune response-regulating cell surface receptor signaling pathway
P682 biological process ... Q14913302 (regulation of innate immune response) regulation of innate immune response
P682 biological process ... Q14916317 (immune system process) immune system process
P682 biological process ... Q15328828 (peptidyl-tyrosine autophosphorylation) peptidyl-tyrosine autophosphorylation
P681 cell component ... Q29548 (plasma membrane) plasma membrane
P681 cell component ... Q39572 (mitochondrion) mitochondrion
P681 cell component ... Q79899 (cytoplasm) cytoplasm
P681 cell component ... Q154626 (cytoskeleton) cytoskeleton
P681 cell component ... Q220599 (cytosol) cytosol
P681 cell component ... Q4692265 (aggresome) aggresome
P681 cell component ... Q14330614 (mitochondrial inner membrane) mitochondrial inner membrane
P681 cell component ... Q14349455 (membrane) membrane
P681 cell component ... Q14353100 (cell projection) cell projection
P681 cell component ... Q14645596 (extracellular region) extracellular region
P681 cell component ... Q14758893 (secretory granule lumen) secretory granule lumen
P681 cell component ... Q14819224 (mitochondrial intermembrane space) mitochondrial intermembrane space
P681 cell component ... Q14860845 (actin cytoskeleton) actin cytoskeleton
P681 cell component ... Q903634 (extracellular exosome) extracellular exosome
P681 cell component ... Q14883311 (ruffle membrane) ruffle membrane
P681 cell component ... Q14905148 (extrinsic component of cytoplasmic side of plasma membrane) extrinsic component of cytoplasmic side of plasma membrane
P702 encoded by ... Q17928333 (FGR) FGR
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P527 has part(s) ... Q24719835 (tyrosine-protein kinase, catalytic domain) tyrosine-protein kinase, catalytic domain
P527 has part(s) ... Q24738472 (tyrosine-protein kinase, active site) tyrosine-protein kinase, active site
P527 has part(s) ... Q24740842 (serine-threonine/tyrosine-protein kinase, catalytic domain) serine-threonine/tyrosine-protein kinase, catalytic domain
P527 has part(s) ... Q24768234 (protein kinase domain) protein kinase domain
P527 has part(s) ... Q24769051 (protein kinase, ATP binding site) protein kinase, ATP binding site
P527 has part(s) ... Q24771787 (SH3 domain) SH3 domain
P527 has part(s) ... Q24780316 (SH2 domain) SH2 domain
P527 has part(s) ... Q32855875 (Tyrosine-protein kinase Fgr, SH2 domain) Tyrosine-protein kinase Fgr, SH2 domain
P31 instance of ... Q8054 (protein) protein
P680 molecular function ... Q167149 (protein binding) protein binding
P680 molecular function ... Q14817981 (ATP binding) ATP binding
P680 molecular function ... Q14817984 (protein kinase binding) protein kinase binding
P680 molecular function ... Q14819233 (signaling receptor binding) signaling receptor binding
P680 molecular function ... Q14820641 (protein kinase activity) protein kinase activity
P680 molecular function ... Q14840131 (transferase activity) transferase activity
P680 molecular function ... Q14860365 (nucleotide binding) nucleotide binding
P680 molecular function ... Q14863082 (kinase activity) kinase activity
P680 molecular function ... Q14863338 (protein tyrosine kinase activity) protein tyrosine kinase activity
P680 molecular function ... Q14873985 (non-membrane spanning protein tyrosine kinase activity) non-membrane spanning protein tyrosine kinase activity
P680 molecular function ... Q14905186 (phosphotyrosine residue binding) phosphotyrosine residue binding
P680 molecular function ... Q21097212 (immunoglobulin receptor binding) immunoglobulin receptor binding
P680 molecular function ... Q21097221 (Fc-gamma receptor I complex binding) Fc-gamma receptor I complex binding
P361 part of ... Q24726164 (Protein kinase-like domain superfamily) Protein kinase-like domain superfamily
P361 part of ... Q41797170 (SH3-like domain superfamily) SH3-like domain superfamily
P361 part of ... Q41797956 (SH2 domain superfamily) SH2 domain superfamily
P361 part of ... Q50261758 (Src family kinases (SFKs) [cytosol]) Src family kinases (SFKs) [cytosol]
P361 part of ... Q83130430 (Tyrosine-protein kinase, catalytic domain, protein family) Tyrosine-protein kinase, catalytic domain, protein family
P361 part of ... Q83137014 (Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family) Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family
P361 part of ... Q83138186 (Protein kinase domain, protein family) Protein kinase domain, protein family
P361 part of ... Q83140574 (SH3 domain, protein family) SH3 domain, protein family
P361 part of ... Q83164644 (SH2 domain, protein family) SH2 domain, protein family
P361 part of ... Q83170552 (Tyrosine-protein kinase Fgr, SH2 domain, protein family) Tyrosine-protein kinase Fgr, SH2 domain, protein family
P361 part of ... Q95352684 (Tyrosine-protein kinase, active site, protein family) Tyrosine-protein kinase, active site, protein family
P361 part of ... Q95354221 (Protein kinase, ATP binding site, protein family) Protein kinase, ATP binding site, protein family

External Ids
P705Ensembl protein IDENSP00000363116
P705Ensembl protein IDENSP00000382126
P705Ensembl protein IDENSP00000407670
P705Ensembl protein IDENSP00000363115
P705Ensembl protein IDENSP00000363117
P637RefSeq protein IDNP_001036194
P637RefSeq protein IDNP_001036212
P637RefSeq protein IDNP_005239
P637RefSeq protein IDXP_006710515
P637RefSeq protein IDXP_011539312
P637RefSeq protein IDXP_011539313
P637RefSeq protein IDXP_011539314
P637RefSeq protein IDXP_011539315
P637RefSeq protein IDXP_011539316
P637RefSeq protein IDXP_016856162
P637RefSeq protein IDXP_016856163
P352UniProt protein IDP09769

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