Chlorproguanil-dapsone-artesunate versus artemether-lumefantrine: a randomized, double-blind phase III trial in African children and adolescents with uncomplicated Plasmodium falciparum malaria

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Chlorproguanil-dapsone-artesunate versus artemether-lumefantrine: a randomized, double-blind phase III trial in African children and adolescents with uncomplicated Plasmodium falciparum malaria is …
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scholarly articleQ13442814

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P819ADS bibcode2009PLoSO...4.6682P
P356DOI10.1371/JOURNAL.PONE.0006682
P932PMC publication ID2724683
P698PubMed publication ID19690618
P5875ResearchGate publication ID26751382

P50authorBrian GreenwoodQ4963885
Steffen BorrmannQ30103006
Akintunde SowunmiQ76590013
Peter WinstanleyQ106879348
Zul PremjiQ114316221
Seth Owusu-AgyeiQ47007270
P2093author name stringStephen A Ward
Stephan Duparc
Fabian Esamai
Stephen Oguche
Allan Pamba
Rich E Umeh
Paula L Kirby
Robert Guiguemdé
Emmanuel U Ezedinachi
Lynda Kellam
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Open-label comparative clinical study of chlorproguanil-dapsone fixed dose combination (Lapdap) alone or with three different doses of artesunate for uncomplicated Plasmodium falciparum malariaQ28472247
An open label, randomised trial of artesunate+amodiaquine, artesunate+chlorproguanil-dapsone and artemether-lumefantrine for the treatment of uncomplicated malariaQ28473004
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Efficacy and safety of the six-dose regimen of artemether-lumefantrine in pediatrics with uncomplicated Plasmodium falciparum malaria: a pooled analysis of individual patient data.Q31043633
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Artemether-lumefantrine versus amodiaquine plus sulfadoxine-pyrimethamine for uncomplicated falciparum malaria in Burkina Faso: a randomised non-inferiority trialQ38399521
Comparison of chlorproguanil-dapsone with sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in young African children: double-blind randomised controlled trialQ38870092
Distinguishing recrudescence from reinfection in a longitudinal antimalarial drug efficacy study: comparison of results based on genotyping of msp-1, msp-2, and glurp.Q38883375
A randomised trial to assess the efficacy and safety of chlorproguanil/dapsone + artesunate for the treatment of uncomplicated Plasmodium falciparum malariaQ38998772
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At least five polymorphic mutants account for the prevalence of glucose-6-phosphate dehydrogenase deficiency in AlgeriaQ39289655
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The haemolytic effects of diaphenylsulfone (DDS) in normal subjects and in those with glucose-6-phosphate-dehydrogenase deficiencyQ40656977
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Randomized comparison of amodiaquine plus sulfadoxine-pyrimethamine, artemether-lumefantrine, and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in Burkina FasoQ43932437
Efficacy of artesunate plus amodiaquine versus that of artemether-lumefantrine for the treatment of uncomplicated childhood Plasmodium falciparum malaria in Zanzibar, TanzaniaQ43947607
Moderate effect of artemisinin-based combination therapy on transmission of Plasmodium falciparumQ44167789
Molecular epidemiology and activity of erythrocyte G6PD variants in a homogeneous Nigerian populationQ44179949
Molecular heterogeneity of glucose-6-phosphate dehydrogenase A-.Q46577039
High efficacy of two artemisinin-based combinations (artemether-lumefantrine and artesunate plus amodiaquine) for acute uncomplicated malaria in Ibadan, NigeriaQ46667800
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectmalariaQ12156
Plasmodium falciparumQ311383
artesunateQ707939
lumefantrineQ904464
teenagerQ1492760
Plasmodium falciparum malariaQ18554672
phase III clinical trialQ42824827
P304page(s)e6682
P577publication date2009-01-01
P1433published inPLOS OneQ564954
P1476titleChlorproguanil-dapsone-artesunate versus artemether-lumefantrine: a randomized, double-blind phase III trial in African children and adolescents with uncomplicated Plasmodium falciparum malaria
P478volume4

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