apolipoprotein A5

mammalian protein found in Homo sapiens

apolipoprotein A5 is …
instance of (P31):
proteinQ8054

External links are
P705Ensembl protein IDENSP00000227665
ENSP00000399701
ENSP00000445002
ENSP00000501141
P486MeSH descriptor IDD000072040
P672MeSH tree codeD10.532.091.200.575
D12.776.070.400.200.575
D12.776.521.120.200.575
P637RefSeq protein IDNP_001160070
NP_001358833
NP_443200
P2892UMLS CUIC4255107
P352UniProt protein IDQ6Q788

P682biological processacylglycerol homeostasisQ21097374
cholesterol biosynthetic processQ14599306
positive regulation of lipid biosynthetic processQ14761956
triglyceride metabolic processQ14819245
regulation of intestinal cholesterol absorptionQ14851915
positive regulation of cholesterol esterificationQ14859613
positive regulation of fatty acid biosynthetic processQ14859629
triglyceride catabolic processQ14864750
very-low-density lipoprotein particle remodelingQ14864752
lipoprotein metabolic processQ14864753
triglyceride homeostasisQ14864754
neuron projection regenerationQ14864877
positive regulation of receptor-mediated endocytosisQ14865472
cholesterol homeostasisQ14872722
lipid transportQ14872727
post-translational protein modificationQ898362
reverse cholesterol transportQ7318217
phosphatidylcholine metabolic processQ14878189
cholesterol effluxQ14890389
phospholipid effluxQ14890392
high-density lipoprotein particle assemblyQ14890399
regulation of cholesterol transportQ14904545
tissue regenerationQ14906266
regulation of lipid metabolic processQ14906369
positive regulation of lipoprotein lipase activityQ14910995
positive regulation of triglyceride catabolic processQ14916268
positive regulation of very-low-density lipoprotein particle remodelingQ14916269
triglyceride-rich lipoprotein particle remodelingQ14916270
positive regulation of lipid catabolic processQ14916406
P681cell componentchylomicronQ423126
endoplasmic reticulum lumenQ14633848
extracellular regionQ14645596
very-low-density lipoprotein particleQ14864742
low-density lipoprotein particleQ14872701
blood microparticleQ21095089
extracellular spaceQ1385443
high-density lipoprotein particleQ14878180
P702encoded byAPOA5Q18049241
P703found in taxonHomo sapiensQ15978631
P680molecular functionlipase activator activityQ21173177
cholesterol transfer activityQ29573259
lipoprotein particle receptor bindingQ13667398
lipid bindingQ14358833
enzyme bindingQ14599289
heparin bindingQ14819453
cholesterol bindingQ14859820
phospholipid bindingQ14859884
enzyme activator activityQ14878167
lipase bindingQ21095126
phosphatidylcholine bindingQ14878186
low-density lipoprotein particle receptor bindingQ14890332
phosphatidylcholine-sterol O-acyltransferase activator activityQ14890337
lipoprotein lipase activator activityQ14910979
P361part ofApolipoprotein A/EQ24719973

Reverse relations

has part(s) (P527)
Q50274733APOA4,APOA5,APOC2,CIDEC,FGF21 [cytosol]
Q50293431Expression of APOA5
Q50269397FAM20C substrates [endoplasmic reticulum lumen]
Q50299756chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols

main subject (P921)
Q24305221APOA5 gene variants, lipoprotein particle distribution, and progression of coronary heart disease: results from the LOCAT study
Q24291759An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing
Q24298481Apolipoprotein A-V interaction with members of the low density lipoprotein receptor gene family
Q24301565Apolipoprotein A-V-heparin interactions: implications for plasma lipoprotein metabolism
Q24291737Apolipoprotein A-V: a novel apolipoprotein associated with an early phase of liver regeneration
Q24314838Effects of six APOA5 variants, identified in patients with severe hypertriglyceridemia, on in vitro lipoprotein lipase activity and receptor binding
Q24313182Efficient lowering of triglyceride levels in mice by human apoAV protein variants associated with hypertriglyceridemia
Q24294823Identification of lipid binding and lipoprotein lipase activation domains of human apoAV
Q24322206Longitudinal analysis of haplotypes and polymorphisms of the APOA5 and APOC3 genes associated with variation in serum triglyceride levels: the Bogalusa Heart Study
Q24294997Mechanism of triglyceride lowering in mice expressing human apolipoprotein A5
Q24315970Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides
Q24305368Structure and interfacial properties of human apolipoprotein A-V
Q24311849The novel apolipoprotein A5 is present in human serum, is associated with VLDL, HDL, and chylomicrons, and circulates at very low concentrations compared with other apolipoproteins

Q50373814p-APOA5 [endoplasmic reticulum lumen]subclass ofP279
Q18049241APOA5encodesP688

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