review article | Q7318358 |
scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1016228805 |
P356 | DOI | 10.1186/1750-1172-1-10 |
P932 | PMC publication ID | 1475837 |
P698 | PubMed publication ID | 16722529 |
P5875 | ResearchGate publication ID | 7059366 |
P50 | author | Alan T Nurden | Q88562454 |
P2860 | cites work | Family screening for a Glanzmann's thrombasthenia mutation using PCR-SSCP. | Q45817673 |
The effect of platelets on fibrin gel structure formed in the presence of recombinant factor VIIa in hemophilia plasma and in plasma from a patient with Glanzmann thrombasthenia | Q45880844 | ||
Specific synergy of multiple substrate-receptor interactions in platelet thrombus formation under flow. | Q45967882 | ||
Prophylactic and therapeutic recombinant factor VIIa administration to patients with Glanzmann's thrombasthenia: results of an international survey. | Q47287128 | ||
Prenatal diagnosis of Glanzmann thrombasthenia using the polymorphic markers BRCA1 and THRA1 on chromosome 17. | Q47720581 | ||
Triple heterozygosity in the integrin alphaIIb subunit in a patient with Glanzmann's thrombasthenia. | Q47730309 | ||
The human integrin beta3 gene is 63 kb and contains a 5'-UTR sequence regulating expression. | Q48043111 | ||
Rational use of the PFA-100 device for screening of platelet function disorders and von Willebrand disease. | Q52039815 | ||
Presentation and pattern of symptoms in 382 patients with Glanzmann thrombasthenia in Iran | Q61040725 | ||
CD40L stabilizes arterial thrombi by a β3 integrin–dependent mechanism | Q63354517 | ||
Detection of the Glanzmann's thrombasthenia mutations in Arab and Iraqi-Jewish patients by polymerase chain reaction and restriction analysis of blood or urine samples | Q67866855 | ||
Prenatal diagnosis of Glanzmann's thrombasthenia | Q69875023 | ||
Complete correction of Glanzmann's thrombasthenia by allogeneic bone-marrow transplantation | Q69888542 | ||
The formation of Ca++-dependent complexes of platelet membrane glycoproteins IIb and IIIa in solution as determined by crossed immunoelectrophoresis | Q70549345 | ||
The molecular genetic basis of Glanzmann's thrombasthenia in a gypsy population in France: identification of a new mutation on the alpha IIb gene | Q71911678 | ||
The use of recombinant factor VIIa in children with inherited platelet function disorders | Q73320925 | ||
The role of platelets in venous thrombosis: a patient with Glanzmann's thrombasthenia and a factor V Leiden mutation suffering from deep venous thrombosis | Q73691007 | ||
Upregulation of osteoclast alpha2beta1 integrin compensates for lack of alphavbeta3 vitronectin receptor in Iraqi-Jewish-type Glanzmann thrombasthenia | Q73903668 | ||
Thrombocytoasthenia and thrombocytopathia-old names and new diseases | Q74242714 | ||
Glanzmann's thrombasthenia: identification of 19 new mutations in 30 patients | Q74359721 | ||
Analysis of the amino acid requirement for a normal alphaIIbbeta3 maturation at alphaIIbGlu324 commonly mutated in Glanzmann thrombasthenia | Q78321200 | ||
Protein A Sepharose immunoadsorption can restore the efficacy of platelet concentrates in patients with Glanzmann's thrombasthenia and anti-glycoprotein IIb-IIIa antibodies | Q78630148 | ||
Dissociation between fibrinogen and fibrin interaction with platelets in patients with different subtypes of Glanzmann's thrombasthenia: studies in an ex vivo perfusion chamber model | Q78630152 | ||
The molecular genetics of Glanzmann's thrombasthenia | Q79774022 | ||
Elevated Flk1 (vascular endothelial growth factor receptor 2) signaling mediates enhanced angiogenesis in beta3-integrin-deficient mice | Q81085089 | ||
Mutations in GPIIIa molecule as a cause for Glanzmann thrombasthenia in Indian patients | Q81479252 | ||
Integrins: versatility, modulation, and signaling in cell adhesion | Q27860844 | ||
Ser-752-->Pro mutation in the cytoplasmic domain of integrin beta 3 subunit and defective activation of platelet integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) in a variant of Glanzmann thrombasthenia | Q28118972 | ||
Molecular basis of Glanzmann's Thrombasthenia and current strategies in treatment | Q28216926 | ||
Integrins: dynamic scaffolds for adhesion and signaling in platelets | Q28267584 | ||
Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen | Q28588951 | ||
Human IgG monoclonal anti-alpha(IIb)beta(3)-binding fragments derived from immunized donors using phage display | Q30805062 | ||
Specific roles for platelet surface glycoproteins in platelet function | Q33339641 | ||
Acquired Glanzmann's thrombasthenia without thrombocytopenia: a severe acquired autoimmune bleeding disorder | Q33363083 | ||
Autoimmune thrombocytopenic purpura (AITP) and acquired thrombasthenia due to autoantibodies to GP IIb-IIIa in a patient with an unusual platelet membrane glycoprotein composition | Q33501616 | ||
Platelet glycoprotein IIb/IIIa inhibitors: basic and clinical aspects. | Q33790993 | ||
Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclasts | Q33939357 | ||
A new variant of Glanzmann's thrombasthenia (Strasbourg I). Platelets with functionally defective glycoprotein IIb-IIIa complexes and a glycoprotein IIIa 214Arg----214Trp mutation | Q34221553 | ||
Platelet vitronectin receptor expression differentiates Iraqi-Jewish from Arab patients with Glanzmann thrombasthenia in Israel | Q34571418 | ||
Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics | Q35213036 | ||
Gene therapy for platelet disorders: studies with Glanzmann's thrombasthenia | Q35589483 | ||
Folding of the N-terminal, ligand-binding region of integrin alpha-subunits into a beta-propeller domain | Q35899468 | ||
Truncation of the cytoplasmic domain of beta3 in a variant form of Glanzmann thrombasthenia abrogates signaling through the integrin alpha(IIb)beta3 complex | Q37374506 | ||
The molecular genetic basis of Glanzmann thrombasthenia in the Iraqi-Jewish and Arab populations in Israel | Q37478529 | ||
Glanzmann's thrombasthenia: the spectrum of clinical disease | Q37909047 | ||
A single amino acid substitution flanking the fourth calcium binding domain of alpha IIb prevents maturation of the alpha IIb beta 3 integrin complex | Q38311244 | ||
A beta 3 integrin mutation abolishes ligand binding and alters divalent cation-dependent conformation | Q38339624 | ||
Major mutations in calf-1 and calf-2 domains of glycoprotein IIb in patients with Glanzmann thrombasthenia enable GPIIb/IIIa complex formation, but impair its transport from the endoplasmic reticulum to the Golgi apparatus | Q40667595 | ||
Two novel mutations in the alpha IIb calcium-binding domains identify hydrophobic regions essential for alpha IIbbeta 3 biogenesis | Q40691230 | ||
Missense mutations in the beta(3) subunit have a different impact on the expression and function between alpha(IIb)beta(3) and alpha(v)beta(3). | Q40755458 | ||
A point mutation in the cysteine-rich domain of glycoprotein (GP) IIIa results in the expression of a GPIIb-IIIa (alphaIIbbeta3) integrin receptor locked in a high-affinity state and a Glanzmann thrombasthenia-like phenotype | Q40776610 | ||
Probing conformational changes in the I-like domain and the cysteine-rich repeat of human beta 3 integrins following disulfide bond disruption by cysteine mutations: identification of cysteine 598 involved in alphaIIbbeta3 activation | Q40785864 | ||
R to Q amino acid substitution in the GFFKR sequence of the cytoplasmic domain of the integrin IIb subunit in a patient with a Glanzmann's thrombasthenia-like syndrome | Q40991444 | ||
Patients with Glanzmann thrombasthenia lacking platelet glycoprotein alpha(IIb)beta(3) (GPIIb/IIIa) and alpha(v)beta(3) receptors are not protected from atherosclerosis | Q43904601 | ||
Recombinant factor VIIa enhances deposition of platelets with congenital or acquired alpha IIb beta 3 deficiency to endothelial cell matrix and collagen under conditions of flow via tissue factor-independent thrombin generation | Q44201546 | ||
A naturally occurring Tyr143His alpha IIb mutation abolishes alpha IIb beta 3 function for soluble ligands but retains its ability for mediating cell adhesion and clot retraction: comparison with other mutations causing ligand-binding defects | Q44265494 | ||
Dynamics of GPIIb/IIIa-mediated platelet-platelet interactions in platelet adhesion/thrombus formation on collagen in vitro as revealed by videomicroscopy | Q44279137 | ||
An association of candidate gene haplotypes and bleeding severity in von Willebrand disease (VWD) type 1 pedigrees | Q44958587 | ||
P275 | copyright license | Creative Commons Attribution 2.0 Generic | Q19125117 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Glanzmann's thrombasthenia | Q1529258 |
P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
P304 | page(s) | 10 | |
P577 | publication date | 2006-04-06 | |
P1433 | published in | Orphanet Journal of Rare Diseases | Q15756117 |
P1476 | title | Glanzmann thrombasthenia | |
P478 | volume | 1 |
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Q37903933 | Advances in our understanding of the molecular basis of disorders of platelet function |
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Q35013677 | Delineating the roles of the GPIIb/IIIa and GP-Ib-IX-V platelet receptors in mediating platelet adhesion to adsorbed fibrinogen and albumin. |
Q41926876 | Diagnosis and Management of Inherited Platelet Disorders |
Q33383957 | Dominant inheritance of a novel integrin beta3 mutation associated with a hereditary macrothrombocytopenia and platelet dysfunction in two Italian families |
Q39181193 | Epistaxis as a Common Presenting Symptom of Glanzmann's Thrombasthenia, a Rare Qualitative Platelet Disorder: Illustrative Case Examples |
Q51751582 | Excessive gingival bleeding in two patients with Glanzmann thrombasthenia. |
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Q35230088 | Founder effect and estimation of the age of the French Gypsy mutation associated with Glanzmann thrombasthenia in Manouche families |
Q30487560 | Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins |
Q54466253 | GDF-15 prevents platelet integrin activation and thrombus formation. |
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Q33436665 | Glanzmann thrombasthenia in pregnancy: Optimising maternal and fetal outcomes |
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Q33375248 | Murine models of platelet diseases |
Q34120335 | Nasal packing with strips of cured pork as treatment for uncontrollable epistaxis in a patient with Glanzmann thrombasthenia |
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Q42365100 | Novel Mutations in the GPIIb and GPIIIa Genes in Glanzmann Thrombasthenia |
Q53393838 | Novel and recurrent mutations of ITGA2B and ITGB3 genes in Korean patients with Glanzmann thrombasthenia. |
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