| scholarly article | Q13442814 |
| P2093 | author name string | P J Newman | |
| R Wang | |||
| D R Ambruso | |||
| S J Shattil | |||
| P2860 | cites work | Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit | Q24316118 |
| An interaction between alpha-actinin and the beta 1 integrin subunit in vitro | Q24317203 | ||
| Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains | Q24672461 | ||
| Signal transduction from the extracellular matrix | Q24675031 | ||
| A new technique for the assay of infectivity of human adenovirus 5 DNA | Q27860797 | ||
| Integrins: versatility, modulation, and signaling in cell adhesion | Q27860844 | ||
| Alpha L beta 2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1, a cytoplasmic regulatory molecule | Q28115147 | ||
| Ser-752-->Pro mutation in the cytoplasmic domain of integrin beta 3 subunit and defective activation of platelet integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) in a variant of Glanzmann thrombasthenia | Q28118972 | ||
| Regulation of fibronectin receptor distribution | Q28186395 | ||
| Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling | Q28256301 | ||
| Integrins: emerging paradigms of signal transduction | Q28283614 | ||
| Interaction of plasma membrane fibronectin receptor with talin--a transmembrane linkage | Q28285095 | ||
| Integrins: a family of cell surface receptors | Q28288125 | ||
| Integrins and signal transduction pathways: the road taken | Q29547895 | ||
| Integrin function: molecular hierarchies of cytoskeletal and signaling molecules | Q29618843 | ||
| Molecular basis for Glanzmann's thrombasthenia (GT) in a compound heterozygote with glycoprotein IIb gene: a proposal for the classification of GT based on the biosynthetic pathway of glycoprotein IIb-IIIa complex | Q30983350 | ||
| Exposure of platelet fibrinogen receptors by ADP and epinephrine | Q33473239 | ||
| Amino acid 489 is encoded by a mutational "hot spot" on the beta 3 integrin chain: the CA/TU human platelet alloantigen system | Q33489307 | ||
| Platelets have more than one binding site for von Willebrand factor | Q33821754 | ||
| Glanzmann thrombasthenia secondary to a Gly273-->Asp mutation adjacent to the first calcium-binding domain of platelet glycoprotein IIb. | Q34119585 | ||
| A deletion in the gene for glycoprotein IIb associated with Glanzmann's thrombasthenia | Q34177601 | ||
| Glanzmann thrombasthenia resulting from a single amino acid substitution between the second and third calcium-binding domains of GPIIb. Role of the GPIIb amino terminus in integrin subunit association | Q34207017 | ||
| A new variant of Glanzmann's thrombasthenia (Strasbourg I). Platelets with functionally defective glycoprotein IIb-IIIa complexes and a glycoprotein IIIa 214Arg----214Trp mutation | Q34221553 | ||
| The genomic organization of platelet glycoprotein IIIa | Q34588350 | ||
| Retention of the glycoprotein IIb-IIIa complex in the isolated platelet cytoskeleton. Effects of separable assembly of platelet pseudopodal and contractile cytoskeletons | Q34615338 | ||
| Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction | Q34719628 | ||
| Inside-out integrin signalling | Q35455358 | ||
| An amino acid polymorphism within the RGD binding domain of platelet membrane glycoprotein IIIa is responsible for the formation of the Pena/Penb alloantigen system | Q35609124 | ||
| A genetic analysis of integrin function: Glanzmann thrombasthenia in vitro | Q36030185 | ||
| Identification of membrane proteins mediating the interaction of human platelets | Q36201513 | ||
| Dynamic cytoskeleton-integrin associations induced by cell binding to immobilized fibronectin | Q36222281 | ||
| Role of platelet membrane glycoprotein IIb-IIIa in agonist-induced tyrosine phosphorylation of platelet proteins | Q36224276 | ||
| Evidence for the selective association of a subpopulation of GPIIb-IIIa with the actin cytoskeletons of thrombin-activated platelets | Q36232933 | ||
| Integrin cytoplasmic domains mediate inside-out signal transduction | Q36233869 | ||
| Control of intracellular pH and growth by fibronectin in capillary endothelial cells | Q36383431 | ||
| An exon 28 mutation resulting in alternative splicing of the glycoprotein IIb transcript and Glanzmann's thrombasthenia. | Q36742556 | ||
| Affinity modulation of the alpha IIb beta 3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor | Q36772797 | ||
| Integrins as a primary signal transduction molecule regulating monocyte immediate-early gene induction | Q37219576 | ||
| Glanzmann thrombasthenia. Cooperation between sequence variants in cis during splice site selection | Q37360713 | ||
| The molecular genetic basis of Glanzmann thrombasthenia in the Iraqi-Jewish and Arab populations in Israel | Q37478529 | ||
| Insoluble fibronectin activates the Na/H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shape | Q37588910 | ||
| Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins | Q37597345 | ||
| Integrins and other cell adhesion molecules | Q37944961 | ||
| "Inside-out" signal transduction inhibited by isolated integrin cytoplasmic domains. | Q38306250 | ||
| A single amino acid substitution flanking the fourth calcium binding domain of alpha IIb prevents maturation of the alpha IIb beta 3 integrin complex | Q38311244 | ||
| A beta 3 integrin mutation abolishes ligand binding and alters divalent cation-dependent conformation | Q38339624 | ||
| The platelet membrane glycoprotein IIb-IIIa complex. | Q39195582 | ||
| The extracellular matrix as a cell survival factor | Q40241699 | ||
| Glanzmann thrombasthenia: new insights from an historical perspective. | Q40577006 | ||
| Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein | Q40642924 | ||
| Glanzmann thrombasthenia due to a two amino acid deletion in the fourth calcium-binding domain of alpha IIb: demonstration of the importance of calcium-binding domains in the conformation of alpha IIb beta 3. | Q41189169 | ||
| Selective inhibition of integrin function by antibodies specific for ligand-occupied receptor conformers. | Q41226672 | ||
| Quantitation of membrane glycoprotein IIIa on intact human platelets using the monoclonal antibody, AP-3. | Q41393387 | ||
| A fluorescent cellular adhesion assay using insect cell produced human VCAM1 | Q41441436 | ||
| Integrin beta 1- and beta 3-mediated endothelial cell migration is triggered through distinct signaling mechanisms. | Q41564910 | ||
| Regulation of Adhesion to ICAM-1 by the Cytoplasmic Domain of LFA-1 Integrin β Subunit | Q41690746 | ||
| Spreading of human endothelial cells on fibronectin or vitronectin triggers elevation of intracellular free calcium | Q42482813 | ||
| Breaking the integrin hinge. A defined structural constraint regulates integrin signaling | Q43482152 | ||
| Analysis of GPIIb/IIIa receptor number by quantification of 7E3 binding to human platelets. | Q45345575 | ||
| Monoclonal antibodies to ligand-occupied conformers of integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) alter receptor affinity, specificity, and function. | Q46027752 | ||
| A spontaneous mutation of integrin alpha IIb beta 3 (platelet glycoprotein IIb-IIIa) helps define a ligand binding site. | Q46071171 | ||
| Organization of the gene for platelet glycoprotein IIb. | Q46415301 | ||
| On the role of the platelet membrane skeleton in mediating signal transduction. Association of GP IIb-IIIa, pp60c-src, pp62c-yes, and the p21ras GTPase-activating protein with the membrane skeleton. | Q46799641 | ||
| Gel filtration. A new technique for separation of blood platelets from plasma | Q47658132 | ||
| A monoclonal antibody against the platelet fibrinogen receptor contains a sequence that mimics a receptor recognition domain in fibrinogen | Q48306336 | ||
| A monoclonal antibody to a membrane glycoprotein binds only to activated platelets. | Q50921115 | ||
| A point mutation in the integrin beta 3 cytoplasmic domain (S752-->P) impairs bidirectional signaling through alpha IIb beta 3 (platelet glycoprotein IIb-IIIa). | Q52513845 | ||
| Inherited mutations within the calcium-binding sites of the integrin alpha IIb subunit (platelet glycoprotein IIb). Effects of the amino acid side chain and the amino acid position on cation binding. | Q52522519 | ||
| The platelet cytoskeleton stabilizes the interaction between alphaIIbbeta3 and its ligand and induces selective movements of ligand-occupied integrin. | Q53990149 | ||
| Integrin signaling: roles for the cytoplasmic tails of alpha IIb beta 3 in the tyrosine phosphorylation of pp125FAK | Q57446983 | ||
| Alpha v integrins mediate the rise in intracellular calcium in endothelial cells on fibronectin even though they play a minor role in adhesion | Q57446988 | ||
| A conformation-dependent epitope of human platelet glycoprotein IIIa | Q67675819 | ||
| Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase | Q67926191 | ||
| Modulation of the affinity of integrin alpha IIb beta 3 (GPIIb-IIIa) by the cytoplasmic domain of alpha IIb | Q68053643 | ||
| Modulation of platelet function through adhesion receptors. A dual role for glycoprotein IIb-IIIa (integrin alpha IIb beta 3) mediated by fibrinogen and glycoprotein Ib-von Willebrand factor | Q68142029 | ||
| Detection of activated platelets in whole blood using activation-dependent monoclonal antibodies and flow cytometry | Q68160190 | ||
| Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation | Q68940569 | ||
| Interaction of fibronectin-coated beads with attached and spread fibroblasts. Binding, phagocytosis, and cytoskeletal reorganization | Q70275708 | ||
| Peptides derived from a sequence within beta 3 integrin bind to platelet alpha IIb beta 3 (GPIIb-IIIa) and inhibit ligand binding | Q70635935 | ||
| Integrin activation and cytoskeletal interaction are essential for the assembly of a fibronectin matrix | Q70787146 | ||
| The cytoplasmic domain of alphaIIb beta3. A ternary complex of the integrin alpha and beta subunits and a divalent cation | Q71069890 | ||
| Direct binding of the platelet integrin alphaIIbbeta3 (GPIIb-IIIa) to talin. Evidence that interaction is mediated through the cytoplasmic domains of both alphaIIb and beta3 | Q71143866 | ||
| Tyrosine phosphorylation of pp125FAK in platelets requires coordinated signaling through integrin and agonist receptors | Q71623372 | ||
| Effect of cytoplasmic domain mutations on the agonist-stimulated ligand binding activity of the platelet integrin alphaIIbbeta3 | Q71825191 | ||
| Mutation of the cytoplasmic domain of the integrin beta 3 subunit. Differential effects on cell spreading, recruitment to adhesion plaques, endocytosis, and phagocytosis | Q72167879 | ||
| Identification of two structurally and functionally distinct sites on human platelet membrane glycoprotein IIb-IIIa using monoclonal antibodies | Q72779664 | ||
| Interaction of AP-2, a monoclonal antibody specific for the human platelet glycoprotein IIb-IIIa complex, with intact platelets | Q72797414 | ||
| Tyrosine phosphorylation and cytoskeletal reorganization in platelets are triggered by interaction of integrin receptors with their immobilized ligands | Q72854737 | ||
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 2393-2403 | |
| P577 | publication date | 1997-11-01 | |
| P1433 | published in | Journal of Clinical Investigation | Q3186904 |
| P1476 | title | Truncation of the cytoplasmic domain of beta3 in a variant form of Glanzmann thrombasthenia abrogates signaling through the integrin alpha(IIb)beta3 complex | |
| P478 | volume | 100 |
| Q40339375 | A 13-bp deletion in alpha(IIb) gene is a founder mutation that predominates in Palestinian-Arab patients with Glanzmann thrombasthenia |
| Q40766649 | A Val193Met mutation in GPIIIa results in a GPIIb/IIIa receptor with a constitutively high affinity for a small ligand |
| Q43576574 | A membrane-distal segment of the integrin alpha IIb cytoplasmic domain regulates integrin activation. |
| Q39434031 | A mutation in the β3 cytoplasmic tail causes variant Glanzmann thrombasthenia by abrogating transition of αIIb β3 to an active state |
| Q40848368 | A novel leukocyte adhesion deficiency caused by expressed but nonfunctional beta2 integrins Mac-1 and LFA-1. |
| Q89777962 | An intracytoplasmic β3 Leu718 deletion in a patient with a novel platelet phenotype |
| Q37157980 | Antithrombotic effects of targeting alphaIIbbeta3 signaling in platelets |
| Q88418012 | Clinical and molecular insights into Glanzmann's thrombasthenia in China |
| Q36256128 | Complementary roles for receptor clustering and conformational change in the adhesive and signaling functions of integrin alphaIIb beta3 |
| Q46824116 | Cooperative role of the membrane-proximal and -distal residues of the integrin beta3 cytoplasmic domain in regulation of talin-mediated alpha IIb beta3 activation |
| Q36323239 | Critical roles for the COOH-terminal NITY and RGT sequences of the integrin beta3 cytoplasmic domain in inside-out and outside-in signaling |
| Q34158852 | Demystified...adhesion molecule deficiencies |
| Q60369289 | Discoidin-domain receptor coordinates cell-matrix adhesion and collective polarity in migratory cardiopharyngeal progenitors |
| Q51819151 | Distinct roles of ligand affinity and cytoskeletal anchorage in alphaIIbbeta3 (GP IIb/IIIa)-mediated cell aggregation and adhesion. |
| Q57998264 | Divalent Cations Differentially Regulate Integrin αIIbCytoplasmic Tail Binding to β3and to Calcium- and Integrin-binding Protein |
| Q37836200 | Do cell junction protein mutations cause an airway phenotype in mice or humans? |
| Q33383957 | Dominant inheritance of a novel integrin beta3 mutation associated with a hereditary macrothrombocytopenia and platelet dysfunction in two Italian families |
| Q40686073 | Enhanced activation of mitogen-activated protein kinase and myosin light chain kinase by the Pro33 polymorphism of integrin beta 3. |
| Q24681057 | Enhancement of endothelial cell migration and in vitro tube formation by TAP20, a novel beta 5 integrin-modulating, PKC theta-dependent protein |
| Q33383170 | Eptifibatide-induced thrombocytopenia and thrombosis in humans require FcgammaRIIa and the integrin beta3 cytoplasmic domain |
| Q33998332 | Genetic analysis of integrin function in man: LAD-1 and other syndromes. |
| Q21203054 | Glanzmann thrombasthenia |
| Q33571529 | Glanzmann thrombasthenia: state of the art and future directions |
| Q28343605 | Green fluorescent protein (GFP) tagged to the cytoplasmic tail of alphaIIb or beta3 allows the expression of a fully functional integrin alphaIIb(beta3): effect of beta3GFP on alphaIIb(beta3) ligand binding |
| Q35374831 | Hematopoietic reconstitution of SLP-76 corrects hemostasis and platelet signaling through alpha IIb beta 3 and collagen receptors |
| Q98733448 | ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells |
| Q36915881 | Identification of FcgammaRIIa as the ITAM-bearing receptor mediating alphaIIbbeta3 outside-in integrin signaling in human platelets |
| Q77203120 | Integrin affinity modulation |
| Q36429424 | Integrin alphaIIb promoter-targeted expression of gene products in megakaryocytes derived from retrovirus-transduced human hematopoietic cells |
| Q34452068 | Integrin αIIb-mediated PI3K/Akt activation in platelets |
| Q36288115 | Integrin-dependent control of translation: engagement of integrin alphaIIbbeta3 regulates synthesis of proteins in activated human platelets. |
| Q33952812 | L718P mutation in the membrane-proximal cytoplasmic tail of beta 3 promotes abnormal alpha IIb beta 3 clustering and lipid microdomain coalescence, and associates with a thrombasthenia-like phenotype |
| Q77732918 | Low density lipoprotein phosphorylates the focal adhesion-associated kinase p125(FAK) in human platelets independent of integrin alphaIIb beta3 |
| Q36741271 | Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin alphaIIbbeta3 |
| Q28216926 | Molecular basis of Glanzmann's Thrombasthenia and current strategies in treatment |
| Q48034905 | Mutations in the beta3 gene giving rise to type I Glanzmann thrombasthenia in two families in Portugal |
| Q48091008 | Mutations of the integrin αIIb/β3 intracytoplasmic salt bridge cause macrothrombocytopenia and enlarged platelet α-granules. |
| Q28509897 | Nischarin, a novel protein that interacts with the integrin alpha5 subunit and inhibits cell migration |
| Q73300431 | Osteopetrosis and Glanzmann's thrombasthenia in a child |
| Q51806105 | Pathological shear stress directly regulates platelet alphaIIbbeta3 signaling. |
| Q35651723 | Reconstruction of integrin activation |
| Q73538445 | Signal-transducing mechanisms involved in activation of the platelet collagen receptor integrin alpha(2)beta(1) |
| Q24536159 | Structure and function of the platelet integrin alphaIIbbeta3 |
| Q38183284 | Talin and kindlin: the one-two punch in integrin activation |
| Q33381441 | The GPIIb/IIIa (integrin alphaIIbbeta3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend |
| Q46434992 | The Pro33 isoform of integrin beta3 enhances outside-in signaling in human platelets by regulating the activation of serine/threonine phosphatases |
| Q35868825 | The antithrombotic potential of selective blockade of talin-dependent integrin alpha IIb beta 3 (platelet GPIIb-IIIa) activation |
| Q42010861 | The beta3 subunit of the integrin alphaIIbbeta3 regulates alphaIIb-mediated outside-in signaling |
| Q38197886 | The integrin adhesome: from genes and proteins to human disease |
| Q33912945 | The leukocyte integrins |
| Q90310870 | Topological Adaptation of Transmembrane Domains to the Force-Modulated Lipid Bilayer Is a Basis of Sensing Mechanical Force |
| Q53602922 | Tyrosine phosphorylation of the integrin beta 3 subunit regulates beta 3 cleavage by calpain. |
| Q38059249 | Understanding the genetic basis of Glanzmann thrombasthenia: implications for treatment |
Search more.