Abstract is: R. John Collier (born August 6, 1938) is an American microbiologist and biochemist. He is the Maude and Lillian Presley Professor of Microbiology and Immunobiology, Emeritus at Harvard Medical School.
human | Q5 |
P2381 | Academic Tree ID | 17943 |
P11496 | CiNii Research ID | 1140000791878369792 |
P6178 | Dimensions author ID | 0637515620.19 |
P968 | email address | jcollier@hms.harvard.edu |
P646 | Freebase ID | /m/0gm5wtd |
P6594 | Guggenheim fellows ID | r-john-collier |
P269 | IdRef ID | 112210309 |
P213 | ISNI | 0000000037265636 |
P3874 | Justia Patents inventor ID | r-john-collier |
P244 | Library of Congress authority ID | n85263153 |
P6366 | Microsoft Academic ID | 2276864183 |
P271 | NACSIS-CAT author ID | DA06364779 |
P5380 | National Academy of Sciences member ID | 59399 |
P1006 | Nationale Thesaurus voor Auteursnamen ID | 299001202 |
P856 | official website | http://micro.med.harvard.edu/faculty/collier.html |
P496 | ORCID iD | 0000-0002-2427-4239 |
P1153 | Scopus author ID | 7202591916 |
P4012 | Semantic Scholar author ID | 2166180 |
P214 | VIAF ID | 6381890 |
P10832 | WorldCat Entities ID | E39PBJbM9MCxvCmH4rT888wXBP |
P512 | academic degree | Doctor of Philosophy | Q752297 |
P1416 | affiliation | Harvard Medical School | Q49121 |
P166 | award received | Paul Ehrlich and Ludwig Darmstaedter Prize | Q458338 |
Guggenheim Fellowship | Q1316544 | ||
Selman A. Waksman Award in Microbiology | Q2268592 | ||
Fellow of the American Association for the Advancement of Science | Q5442484 | ||
Bristol-Myers Squibb Award for Distinguished Achievement in Infectious Diseases Research | Q30123947 | ||
Fellow of the American Academy of Arts and Sciences | Q52382875 | ||
P27 | country of citizenship | United States of America | Q30 |
P69 | educated at | Harvard University | Q13371 |
University of Geneva | Q503473 | ||
Rice University | Q842909 | ||
P108 | employer | Harvard University | Q13371 |
Harvard Medical School | Q49121 | ||
University of California, Los Angeles | Q174710 | ||
UCLA Division of Life Sciences | Q105427200 | ||
P734 | family name | Collier | Q16865687 |
Collier | Q16865687 | ||
Collier | Q16865687 | ||
P101 | field of work | toxin | Q184651 |
anthrax toxin | Q1935986 | ||
P735 | given name | Robert | Q4927937 |
Robert | Q4927937 | ||
John | Q4925477 | ||
John | Q4925477 | ||
P1412 | languages spoken, written or signed | English | Q1860 |
P463 | member of | National Academy of Sciences | Q270794 |
American Academy of Arts and Sciences | Q463303 | ||
P1559 | name in native language | R. John Collier | |
P106 | occupation | biologist | Q864503 |
biochemist | Q2919046 | ||
microbiologist | Q3779582 | ||
P39 | position held | professor emeritus | Q1240569 |
P21 | sex or gender | male | Q6581097 |
P937 | work location | Boston | Q100 |
Q34712623 | 2001: a year of major advances in anthrax toxin research |
Q35978682 | A dually active anthrax vaccine that confers protection against both bacilli and toxins |
Q42575392 | A hybrid toxin containing fragment A from diphtheria toxin linked to the B protomer of cholera toxin |
Q34684419 | A loop network within the anthrax toxin pore positions the phenylalanine clamp in an active conformation |
Q34721109 | A monoclonal antibody to Bacillus anthracis protective antigen defines a neutralizing epitope in domain 1 |
Q42932650 | A phenylalanine clamp catalyzes protein translocation through the anthrax toxin pore |
Q28610278 | A quantitative study of the interactions of Bacillus anthracis edema factor and lethal factor with activated protective antigen |
Q40056223 | A semisynthesis platform for investigating structure-function relationships in the N-terminal domain of the anthrax Lethal Factor |
Q46090423 | A soluble receptor decoy protects rats against anthrax lethal toxin challenge |
Q30160407 | Acid-induced unfolding of the amino-terminal domains of the lethal and edema factors of anthrax toxin |
Q57214158 | Active-Site Mutations of Diphtheria Toxin: Role of Tyrosine-65 in NAD Binding and ADP-Ribosylation |
Q43761887 | Active-site mutations of diphtheria toxin: effects of replacing glutamic acid-148 with aspartic acid, glutamine, or serine |
Q54633625 | Active-site mutations of the diphtheria toxin catalytic domain: role of histidine-21 in nicotinamide adenine dinucleotide binding and ADP-ribosylation of elongation factor 2. |
Q46476517 | Amino acid residues involved in membrane insertion and pore formation of Clostridium botulinum C2 toxin |
Q44186485 | Amino acid sequence homology between the enzymic domains of diphtheria toxin and Pseudomonas aeruginosa exotoxin A. |
Q42060301 | An approach to characterizing single-subunit mutations in multimeric prepores and pores of anthrax protective antigen |
Q57213891 | Anthrax Toxin |
Q44534485 | Anthrax delivers a lethal blow to host immunity |
Q30481474 | Anthrax lethal toxin induces cell death-independent permeability in zebrafish vasculature |
Q36987540 | Anthrax protective antigen interacts with a specific receptor on the surface of CHO-K1 cells |
Q47594951 | Anthrax protective antigen: efficiency of translocation is independent of the number of ligands bound to the prepore |
Q30175382 | Anthrax protective antigen: prepore-to-pore conversion |
Q33764677 | Anthrax toxin as a molecular tool for stimulation of cytotoxic T lymphocytes: disulfide-linked epitopes, multiple injections, and role of CD4(+) cells |
Q34341387 | Anthrax toxin complexes: heptameric protective antigen can bind lethal factor and edema factor simultaneously |
Q34001191 | Anthrax toxin entry into polarized epithelial cells |
Q30830672 | Anthrax toxin receptor 2 determinants that dictate the pH threshold of toxin pore formation |
Q28572283 | Anthrax toxin receptor 2-dependent lethal toxin killing in vivo |
Q33750314 | Anthrax toxin-mediated delivery in vivo and in vitro of a cytotoxic T-lymphocyte epitope from ovalbumin |
Q37242580 | Anthrax toxin-mediated delivery of a cytotoxic T-cell epitope in vivo |
Q33846416 | Anthrax toxin: channel-forming activity of protective antigen in planar phospholipid bilayers |
Q36750138 | Anthrax toxin: receptor binding, internalization, pore formation, and translocation |
Q34714854 | Antibiotic-based selection for bacterial genes that are specifically induced during infection of a host |
Q36401049 | Antibody-directed cytotoxic agents: use of monoclonal antibody to direct the action of toxin A chains to colorectal carcinoma cells |
Q36579365 | Antiinflammatory cAMP signaling and cell migration genes co-opted by the anthrax bacillus |
Q41737111 | Assembly and disassembly kinetics of anthrax toxin complexes |
Q39365433 | Assembly of anthrax toxin pore: lethal-factor complexes into lipid nanodiscs |
Q41453913 | Association of polyomavirus middle tumor antigen with 14-3-3 proteins |
Q54188364 | Binding of transfer factor II to ribosomal RNA and inhibition of the binding by guanosine nucleotides. |
Q24320977 | Binding stoichiometry and kinetics of the interaction of a human anthrax toxin receptor, CMG2, with protective antigen |
Q37374866 | Biochemical and physiological changes induced by anthrax lethal toxin in J774 macrophage-like cells |
Q40990167 | Characterization of membrane translocation by anthrax protective antigen |
Q42733846 | Chemical dissection of protein translocation through the anthrax toxin pore |
Q38352596 | Circular dichroism of diphtheria toxin, Pseudomonas aeruginosa exotoxin A, and various derivatives |
Q33788263 | Combining anthrax vaccine and therapy: a dominant-negative inhibitor of anthrax toxin is also a potent and safe immunogen for vaccines |
Q41684401 | Conformation of the diphtheria toxin T domain in membranes: a site-directed spin-labeling study of the TH8 helix and TL5 loop |
Q57214204 | Conformational integrity of a recombinant toxoid of Pseudomonas aeruginosa exotoxin A containing a deletion of glutamic acid-553 |
Q42113997 | Conformational switching of the diphtheria toxin T domain |
Q46264263 | Correction: Anthrax Toxin Receptor 2–Dependent Lethal Toxin Killing In Vivo |
Q41947351 | Cross-linked forms of the isolated N-terminal domain of the lethal factor are potent inhibitors of anthrax toxin |
Q27636113 | Crystal structure of the anthrax lethal factor |
Q27734828 | Crystal structure of the anthrax toxin protective antigen |
Q24564886 | Crystal structure of the von Willebrand factor A domain of human capillary morphogenesis protein 2: an anthrax toxin receptor |
Q27729754 | Crystal structure of the zeta isoform of the 14-3-3 protein |
Q57214323 | Crystallization of exotoxin A from Pseudomonas aeruginosa |
Q30175359 | Crystallographic studies of the anthrax lethal toxin |
Q42722552 | Cys-Cys cross-linking shows contact between the N-terminus of lethal factor and Phe427 of the anthrax toxin pore |
Q39612918 | Cytotoxic T-lymphocyte epitopes fused to anthrax toxin induce protective antiviral immunity |
Q41529992 | DNA fragmentation and cytolysis in U937 cells treated with diphtheria toxin or other inhibitors of protein synthesis |
Q30727461 | Designing a polyvalent inhibitor of anthrax toxin |
Q34439762 | Differences in the immunogenicity of native and formalinized cross reacting material (CRM197) of diphtheria toxin in mice and guinea pigs and their implications on the development and control of diphtheria vaccine based on CRMs. |
Q27930295 | Diphthamide synthesis in Saccharomyces cerevisiae: structure of the DPH2 gene. |
Q46396048 | Diphtheria toxin: quantification and assay |
Q33580226 | Disulfide bonds in the ectodomain of anthrax toxin receptor 2 are required for the receptor-bound protective-antigen pore to function |
Q57213936 | Dominant-Negative Mutants of a Toxin Subunit: An Approach to Therapy of Anthrax |
Q46877309 | Effect of 2-fluorohistidine labeling of the anthrax protective antigen on stability, pore formation, and translocation |
Q57214133 | Effect of Anthrax Toxin's Lethal Factor on Ion Channels Formed by the Protective Antigen |
Q57214018 | Effects of Mutations in Proline 345 on Insertion of Diphtheria Toxin into Model Membranes |
Q51822438 | Effects of dynamin inactivation on pathways of anthrax toxin uptake. |
Q33707063 | Effects of introducing a single charged residue into the phenylalanine clamp of multimeric anthrax protective antigen |
Q37124252 | Evidence for a proton-protein symport mechanism in the anthrax toxin channel |
Q24651553 | Evidence that glutamic acid 167 is an active-site residue of Shiga-like toxin I |
Q37695526 | Evidence that translocation of anthrax toxin's lethal factor is initiated by entry of its N terminus into the protective antigen channel |
Q44247948 | Exchange characteristics of calcium ions bound to anthrax protective antigen |
Q37020985 | Expression of a mutant, full-length form of diphtheria toxin in Escherichia coli. |
Q37019195 | Expression of the S-1 catalytic subunit of pertussis toxin in Escherichia coli. |
Q44560499 | Fluorescence resonance energy transfer studies on anthrax lethal toxin |
Q30157196 | Functions of phenylalanine residues within the beta-barrel stem of the anthrax toxin pore |
Q37405396 | Fused polycationic peptide mediates delivery of diphtheria toxin A chain to the cytosol in the presence of anthrax protective antigen |
Q30370145 | GroEL as a molecular scaffold for structural analysis of the anthrax toxin pore. |
Q36802132 | Identification of novel host-targeted compounds that protect from anthrax lethal toxin-induced cell death |
Q30176262 | Identification of residues lining the anthrax protective antigen channel |
Q28204415 | Identification of the cellular receptor for anthrax toxin |
Q50554709 | Imaging the cell entry of the anthrax oedema and lethal toxins with fluorescent protein chimeras. |
Q28189050 | Inhibition of axotomy-induced neuronal apoptosis by extracellular delivery of a Bcl-XL fusion protein |
Q57213769 | Insertion of Anthrax Protective Antigen into Liposomal Membranes |
Q57214029 | Interaction of Diphtheria Toxin T Domain with Molten Globule-Like Proteins and Its Implications for Translocation |
Q45227405 | Interaction of the 20 kDa and 63 kDa fragments of anthrax protective antigen: kinetics and thermodynamics |
Q24329122 | Interaction of the protein kinase Raf-1 with 14-3-3 proteins |
Q46033478 | Interaction of transferase II with the 60 s ribosomal subunit. |
Q34550250 | Interactions of anthrax lethal factor with protective antigen defined by site-directed spin labeling |
Q33995847 | Involvement of domain 3 in oligomerization by the protective antigen moiety of anthrax toxin |
Q34088991 | Locating a residue in the diphtheria toxin channel |
Q33713102 | Mapping dominant-negative mutations of anthrax protective antigen by scanning mutagenesis |
Q43803655 | Mapping the anthrax protective antigen binding site on the lethal and edema factors |
Q34068323 | Mapping the lethal factor and edema factor binding sites on oligomeric anthrax protective antigen |
Q57214076 | Membrane Topography of the T Domain of Diphtheria Toxin Probed with Single Tryptophan Mutants† |
Q57214040 | Membrane Translocation of Charged Residues at the Tips of Hydrophobic Helices in the T Domain of Diphtheria Toxin† |
Q30160208 | Membrane insertion by anthrax protective antigen in cultured cells |
Q40267216 | Membrane translocation and channel-forming activities of diphtheria toxin are blocked by replacing isoleucine 364 with lysine |
Q37535082 | Membrane translocation by anthrax toxin |
Q30153524 | Monitoring the kinetics of the pH-driven transition of the anthrax toxin prepore to the pore by biolayer interferometry and surface plasmon resonance |
Q46945188 | Mutant anthrax toxin B moiety (protective antigen) inhibits angiogenesis and tumor growth |
Q41662769 | Mutational analysis of the helical hairpin region of diphtheria toxin transmembrane domain |
Q36268438 | NAD binding site of diphtheria toxin: identification of a residue within the nicotinamide subsite by photochemical modification with NAD |
Q36639252 | On the role of macrophages in anthrax |
Q46067618 | Organization of diphtheria toxin T domain in bilayers: a site-directed spin labeling study |
Q30167650 | PA63 channel of anthrax toxin: an extended beta-barrel |
Q54623818 | Participation of lysine 516 and phenylalanine 530 of diphtheria toxin in receptor recognition. |
Q36670023 | Phenylalanine-427 of anthrax protective antigen functions in both pore formation and protein translocation |
Q57214052 | Photoaffinity Labeling of Diphtheria Toxin Fragment A with 8-Azidoadenosyl Nicotinamide Adenine Dinucleotide† |
Q40687644 | Photoaffinity labeling of active site residues in ADP-ribosylating toxins |
Q37536131 | Photoaffinity labeling of diphtheria toxin fragment A with NAD: structure of the photoproduct at position 148. |
Q37006249 | Photolabeling of Glu-129 of the S-1 subunit of pertussis toxin with NAD. |
Q30168578 | Point mutations in anthrax protective antigen that block translocation |
Q34502790 | Polylysine-mediated translocation of the diphtheria toxin catalytic domain through the anthrax protective antigen pore |
Q57213970 | Preclinical evaluation of group B streptococcal polysaccharide conjugate vaccines prepared with a modified diphtheria toxin and a recombinant duck hepatitis B core antigen |
Q36435877 | Probing the structure of the diphtheria toxin channel. Reactivity in planar lipid bilayer membranes of cysteine-substituted mutant channels with methanethiosulfonate derivatives |
Q57214142 | Protective antigen-binding domain of anthrax lethal factor mediates translocation of a heterologous protein fused to its amino- or carboxy-terminus |
Q57213803 | Protein Translocation through the Anthrax Toxin Transmembrane Pore is Driven by a Proton Gradient |
Q34188068 | Protein translocation through anthrax toxin channels formed in planar lipid bilayers |
Q54021249 | Proteolytic activation of receptor-bound anthrax protective antigen on macrophages promotes its internalization. |
Q35423582 | Reaction of diphtheria toxin channels with sulfhydryl-specific reagents: observation of chemical reactions at the single molecule level. |
Q39110294 | Receptor-directed chimeric toxins created by sortase-mediated protein fusion |
Q24532114 | Receptor-specific requirements for anthrax toxin delivery into cells |
Q27636598 | Refined crystallographic structure of Pseudomonas aeruginosa exotoxin A and its implications for the molecular mechanism of toxicity |
Q35556378 | Replacement of C-terminal histidines uncouples membrane insertion and translocation in diphtheria toxin T-domain |
Q44925110 | Reversible refolding of the diphtheria toxin T-domain on lipid membranes |
Q33613555 | Reversion of recombinant toxoids: mutations in diphtheria toxin that partially compensate for active-site deletions |
Q34544082 | Role of CypA and Hsp90 in membrane translocation mediated by anthrax protective antigen |
Q38298647 | Role of glutamic acid 988 of human poly-ADP-ribose polymerase in polymer formation. Evidence for active site similarities to the ADP-ribosylating toxins |
Q36437476 | Role of macrophage oxidative burst in the action of anthrax lethal toxin. |
Q42060384 | Roles of Glu 349 and Asp 352 in membrane insertion and translocation by diphtheria toxin |
Q30157192 | Solubilization and characterization of the anthrax toxin pore in detergent micelles |
Q31034679 | Stoichiometry of anthrax toxin complexes |
Q57213811 | Structural Determinants for the Binding of Anthrax Lethal Factor to Oligomeric Protective Antigen |
Q30449676 | Structure of exotoxin A of Pseudomonas aeruginosa at 3.0-Angstrom resolution |
Q24301840 | Structure of heptameric protective antigen bound to an anthrax toxin receptor: a role for receptor in pH-dependent pore formation |
Q27730334 | Structure of the isolated catalytic domain of diphtheria toxin |
Q57084785 | Structure-function relationships in diphtheria toxin channels: I. Determining a minimal channel-forming domain |
Q39216259 | Targeting HER2-positive cancer cells with receptor-redirected anthrax protective antigen |
Q28250331 | The crystal structure of diphtheria toxin |
Q36436081 | The diphtheria toxin channel-forming T domain translocates its own NH2-terminal region across planar bilayers |
Q34068311 | The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen |
Q40089051 | The mechanism of ADP-ribosylation of elongation factor 2 catalyzed by fragment A from diphtheria toxin |
Q27642935 | The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor |
Q40563937 | Three dimensional structure of the anthrax toxin translocon-lethal factor complex by cryo-electron microscopy |
Q33734525 | Three-dimensional structure of the anthrax toxin pore inserted into lipid nanodiscs and lipid vesicles |
Q36444940 | Topography of diphtheria Toxin's T domain in the open channel state |
Q35550977 | Translocation of the catalytic domain of diphtheria toxin across planar phospholipid bilayers by its own T domain |
Q35289314 | Ultrasensitive detection of protein translocated through toxin pores in droplet-interface bilayers |
Q34398330 | Understanding the mode of action of diphtheria toxin: a perspective on progress during the 20th century |
Q46720421 | Whole-cell voltage clamp measurements of anthrax toxin pore current |
Q33613504 | pH-dependent insertion of proteins into membranes: B-chain mutation of diphtheria toxin that inhibits membrane translocation, Glu-349----Lys |
Q36380649 | pH-dependent perforation of macrophage phagosomes by listeriolysin O from Listeria monocytogenes. |
Q57821408 | pH-dependent permeabilization of the plasma membrane of mammalian cells by anthrax protective antigen |
Arabic (ar / Q13955) | آر. جون كولير | wikipedia |
R. John Collier | wikipedia | |
R. John Collier | wikipedia | |
Robert John Collier | wikipedia |
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