MiR-185 Targets the DNA Methyltransferases 1 and Regulates Global DNA Methylation in human glioma (scientific article published on September 30, 2011)

The homeotic protein Six3 is a coactivator of the nuclear receptor NOR-1 and a corepressor of the fusion protein EWS/NOR-1 in human extraskeletal myxoid chondrosarcomas

Q24293141

Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry

Q24536837

Epigenetic silencing of the protocadherin family member PCDH-gamma-A11 in astrocytomas

Q24550860

MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B

Q24564757

Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis

Q24656948

The 2007 WHO classification of tumours of the central nervous system

Q24685772

Prediction of mammalian microRNA targets

Q27860498

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Q27860739

MicroRNAs: small RNAs with a big role in gene regulation

Q27860896

MicroRNAs: genomics, biogenesis, mechanism, and function

Q27861070

Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells

Q28245307

Extensive modulation of a set of microRNAs in primary glioblastoma

Q28263314

The epigenomics of cancer

Q28289975

Gene silencing in cancer in association with promoter hypermethylation

Q29617274

Loss of heterozygosity on chromosome 22 in sporadic schwannoma and its relation to the proliferation of tumor cells

Q81366664

Cancer epigenetics

Q81611376

Methylation of RASSF1A, RASSF2A, and HIN-1 is associated with poor outcome after radiotherapy, but not surgery, in oral squamous cell carcinoma

Q84030785

???

Q24685269

The role of DNA methylation in mammalian epigenetics

Q29617979

GAD1 mRNA expression and DNA methylation in prefrontal cortex of subjects with schizophrenia

Q33295394

Evaluation of a 7-day continuous intravenous infusion of decitabine: inhibition of promoter-specific and global genomic DNA methylation

Q33365279

Promoter hypermethylation-mediated inactivation of LRRC4 in gliomas

Q33381892

Discovery of DNA methylation markers in cervical cancer using relaxation ranking

Q33386224

MiR-107 and MiR-185 can induce cell cycle arrest in human non small cell lung cancer cell lines.

Q33494538

CpG island hypermethylation in human astrocytomas

Q33766932

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

Q33888431

An 8-gene signature, including methylated and down-regulated glutathione peroxidase 3, of gastric cancer

Q34090543

Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

Q34188991

A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases

Q34343364

Beyond Watson and Crick: DNA methylation and molecular enzymology of DNA methyltransferases

Q34587622

Methyl-DNA immunoprecipitation (MeDIP): hunting down the DNA methylome.

Q34746842

DNA methylation in cancer: too much, but also too little

Q34770545

Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer.

Q34783833

Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis

Q34888915

Aberrant methylation and down-regulation of TMS1/ASC in human glioblastoma

Q35103214

A microRNA DNA methylation signature for human cancer metastasis

Q36861111

DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer.

Q37350311

ARHI, as a novel suppressor of cell growth and downregulated in human hepatocellular carcinoma, could contribute to hepatocarcinogenesis

Q38289425

Large-scale CpG methylation analysis identifies novel candidate genes and reveals methylation hotspots in acute lymphoblastic leukemia

Q38303652

DNA methyltransferase-mediated transcriptional silencing in malignant glioma: a combined whole-genome microarray and promoter array analysis

Q39847607

Genome-wide identification of aberrantly methylated promoter associated CpG islands in acute lymphocytic leukemia.

Q39975102

Methylation-associated PHOX2B gene silencing is a rare event in human neuroblastoma

Q40086269

Loss of pericentromeric DNA methylation pattern in human glioblastoma is associated with altered DNA methyltransferases expression and involves the stem cell compartment.

Q40102545

Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma.

Q40248583

TP53 promoter methylation in human gliomas

Q40396455

Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide

Q40522471

Frequent epigenetic inactivation of RASSF1A and BLU genes located within the critical 3p21.3 region in gliomas.

Q40595717

Epigenetic inactivation of RASSF1A candidate tumor suppressor gene at 3p21.3 in brain tumors

Q40621367

Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastoma

Q42013793

DNA methylation mediated by a microRNA pathway

Q43104318

Promoter methylation of the DNA repair gene MGMT in astrocytomas is frequently associated with G:C --> A:T mutations of the TP53 tumor suppressor gene

Q43750899

DNA repair gene O6-methylguanine-DNA methyltransferase: promoter hypermethylation associated with decreased expression and G:C to A:T mutations of p53 in brain tumors

Q44263002

Promoter hypermethylation of mismatch repair gene hMLH1 predicts the clinical response of malignant astrocytomas to nitrosourea

Q45299151

Promoter Hypermethylation of the DNA Repair Gene O6‐Methylguanine‐DNA Methyltransferase is an Independent Predictor of Shortened Progression Free Survival in Patients with Low‐grade Diffuse Astrocytomas

Q48311590

Promoter hypermethylation identifies progression risk in bladder cancer.

Q51033077

Deletion of the ANKRD15 gene at 9p24.3 causes parent-of-origin-dependent inheritance of familial cerebral palsy

Q51831412

A genome-wide search identifies epigenetic silencing of somatostatin, tachykinin-1, and 5 other genes in colon cancer.

Q53342370

Aberrant promoter hypermethylation profile of cell cycle regulatory genes in malignant astrocytomas

Q53595703

Frequent loss of heterozygosity on chromosome 22 in hepatocellular carcinoma

Q72970952

Frequent biallelic inactivation and transcriptional silencing of the DIRAS3 gene at 1p31 in oligodendroglial tumors with 1p loss

Q80778544

P433

issue

P407

language of work or name

English

Q1860

P921

main subject

DNA methylation

Q874745

neoplastic gene expression regulation

Q66660300

P304

page(s)

124

P577

publication date

2011-01-01

2011-09-30

P1433

published in

Molecular Cancer

Q15724585

P1476

title

MiR-185 targets the DNA methyltransferases 1 and regulates global DNA methylation in human glioma

MiR-185 Targets the DNA Methyltransferases 1 and Regulates Global DNA Methylation in human glioma

P478

volume

Reverse relations

cites work (P2860)

Q24633772	A Systematic Review of MicroRNA in Glioblastoma Multiforme: Micro-modulators in the Mesenchymal Mode of Migration and Invasion
Q42515905	A composite network of conserved and tissue specific gene interactions reveals possible genetic interactions in glioma.
Q38356196	A major role for microRNAs in glioblastoma cancer stem-like cells
Q26830652	An insight into the various regulatory mechanisms modulating human DNA methyltransferase 1 stability and function
Q36985123	CPEB1, a histone-modified hypomethylated gene, is regulated by miR-101 and involved in cell senescence in glioma
Q55128349	Carbonic anhydrase related protein expression in astrocytomas and oligodendroglial tumors.
Q38668171	Circulating epigenetic biomarkers in melanoma.
Q42578720	Cis-acting elements in its 3' UTR mediate post-transcriptional regulation of KRAS.
Q26998741	DNA methylation and microRNA dysregulation in cancer
Q36497752	DNA methylation is critical for tooth agenesis: implications for sporadic non-syndromic anodontia and hypodontia.
Q33989539	Decreased DGCR8 expression and miRNA dysregulation in individuals with 22q11.2 deletion syndrome
Q54322646	Elevated microRNA-185 is associated with high vascular endothelial growth factor receptor 2 expression levels and high microvessel density in clear cell renal cell carcinoma
Q34392645	Epigenetic alteration and microRNA dysregulation in cancer
Q38319591	Epigenetic alterations in cancer and personalized cancer treatment
Q48227731	Epigenetically controlled Six3 expression regulates glioblastoma cell proliferation and invasion alongside modulating the activation levels of WNT pathway members
Q51770872	Epigenetics and MicroRNAs in Cancer
Q36908574	Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in cervical cancer
Q42250991	Genome-wide screening identifies Plasmodium chabaudi-induced modifications of DNA methylation status of Tlr1 and Tlr6 gene promoters in liver, but not spleen, of female C57BL/6 mice
Q36757053	HBP1-Mediated Transcriptional Regulation of DNA Methyltransferase 1 and Its Impact on Cell Senescence
Q38989340	Hepatitis B virus X protein accelerates hepatocarcinogenesis with partner survivin through modulating miR-520b and HBXIP.
Q90788856	Hypermethylated gene ANKDD1A is a candidate tumor suppressor that interacts with FIH1 and decreases HIF1α stability to inhibit cell autophagy in the glioblastoma multiforme hypoxia microenvironment
Q38430627	Identification of Driver Genes and Key Pathways of Pediatric Brain Tumors and Comparison of Molecular Pathogenesis Based on Pathologic Types
Q91651312	Identification of key genes in invasive clinically non-functioning pituitary adenoma by integrating analysis of DNA methylation and mRNA expression profiles
Q39051113	Identification of miR-185 as a regulator of de novo cholesterol biosynthesis and low density lipoprotein uptake
Q34401887	Inhibition of DNA methyltransferase activity and expression by treatment with the pan-deacetylase inhibitor panobinostat in hepatocellular carcinoma cell lines
Q49874623	Integrative analysis of the epigenetic basis of muscle-invasive urothelial carcinoma.
Q55057712	LRRC4 haplotypes are associated with pituitary adenoma in a Chinese population.
Q42314347	MeDeCom: discovery and quantification of latent components of heterogeneous methylomes.
Q51813662	Metastasis-related miR-185 is a potential prognostic biomarker for hepatocellular carcinoma in early stage
Q35781470	MiR-101 reverses the hypomethylation of the LMO3 promoter in glioma cells
Q39210882	MiR-152 and miR-185 co-contribute to ovarian cancer cells cisplatin sensitivity by targeting DNMT1 directly: a novel epigenetic therapy independent of decitabine
Q38935102	MiR-185 is involved in human breast carcinogenesis by targeting Vegfa
Q47824018	MicroRNA-139-5p/Flt1/Wnt/β-catenin regulatory crosstalk modulates the progression of glioma.
Q38774242	MicroRNA-92a Promotes Colorectal Cancer Cell Growth and Migration by Inhibiting KLF4.
Q36826818	MicroRNAs 185, 96, and 223 Repress Selective High-Density Lipoprotein Cholesterol Uptake through Posttranscriptional Inhibition
Q36588163	Oestrogen receptor β regulates epigenetic patterns at specific genomic loci through interaction with thymine DNA glycosylase.
Q53556224	Plasma miRNAs as early biomarkers for detecting hepatocellular carcinoma.
Q97644181	Protocadherins at the Crossroad of Signaling Pathways
Q38885469	Relationship Between Noncoding RNA Dysregulation and Epigenetic Mechanisms in Cancer
Q64069671	Relationship between single nucleotide polymorphisms in the 3'UTR of amyloid precursor protein and risk of Alzheimer's disease and its mechanism
Q36985088	Repression of ATR pathway by miR-185 enhances radiation-induced apoptosis and proliferation inhibition
Q33781657	SIX3, a tumor suppressor, inhibits astrocytoma tumorigenesis by transcriptional repression of AURKA/B.
Q49788159	The Homeotic Protein SIX3 Suppresses Carcinogenesis and Metastasis through Recruiting the LSD1/NuRD(MTA3) Complex
Q38109412	The emerging role of microRNAs in the pathogenesis of systemic lupus erythematosus
Q51768235	Ultraviolet A irradiation induces senescence in human dermal fibroblasts by down-regulating DNMT1 via ZEB1.
Q51275718	Upregulated miR-9-3p Promotes Cell Growth and Inhibits Apoptosis in Medullary Thyroid Carcinoma by Targeting BLCAP.
Q47134084	let-7b and let-7c microRNAs promote histone H2B ubiquitylation and inhibit cell migration by targeting multiple components of the H2B deubiquitylation machinery
Q36782656	miR-101 reverses hypomethylation of the PRDM16 promoter to disrupt mitochondrial function in astrocytoma cells
Q52945589	miR-107 Promotes Proliferation and Inhibits Apoptosis of Colon Cancer Cells by Targeting Prostate Apoptosis Response-4 (Par4).
Q36545987	miR-124 and miR-506 inhibit colorectal cancer progression by targeting DNMT3B and DNMT1.
Q51037810	miR-126-5p Restoration Promotes Cell Apoptosis in Cervical Cancer by Targeting Bcl2l2.
Q39041981	miR-185 is an independent prognosis factor and suppresses tumor metastasis in gastric cancer
Q38712973	miR-202 Promotes Cell Apoptosis in Esophageal Squamous Cell Carcinoma by Targeting HSF2.
Q38849525	miR-25 promotes glioblastoma cell proliferation and invasion by directly targeting NEFL.
Q38780114	miRNA-497 Negatively Regulates the Growth and Motility of Chondrosarcoma Cells by Targeting Cdc25A.
Q34286618	miRNAs and cancer: An epigenetics view

P6179	Dimensions Publication ID	1001668316
P356	DOI	10.1186/1476-4598-10-124
P953	full work available online at	https://europepmc.org/articles/PMC3193026
		https://europepmc.org/articles/PMC3193026?pdf=render
		https://link.springer.com/content/pdf/10.1186/1476-4598-10-124.pdf
		https://molecular-cancer.biomedcentral.com/counter/pdf/10.1186/1476-4598-10-124
P932	PMC publication ID	3193026
P698	PubMed publication ID	21962230
P5875	ResearchGate publication ID	51684315