Laoise McNamara

Irish biomedical engineer

Laoise McNamara is …
instance of (P31):
humanQ5

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P2080AcademiaNet ID1144670
P6178Dimensions author ID0635631206.97
P1960Google Scholar author IDWd9eK9AAAAAJ
P496ORCID iD0000-0002-5050-9230
P2038ResearchGate profile IDLaoise_Mcnamara
P10861Springer Nature person ID0635631206.97
P2002X usernameLaoiseMcnamara

P27country of citizenshipIrelandQ27
P108employerUniversity of GalwayQ644478
P734family nameMcNamaraQ21450738
McNamaraQ21450738
McNamaraQ21450738
P735given nameLaoiseQ64153702
LaoiseQ64153702
P106occupationbiomedical engineerQ19902880
P21sex or genderfemaleQ6581072
P8687social media followers1255

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author (P50)
Q47865863* Mimicking the Biochemical and Mechanical Extracellular Environment of the Endochondral Ossification Process to Enhance the In Vitro Mineralization Potential of Human Mesenchymal Stem Cells.
Q91975746A Developmental Engineering-Based Approach to Bone Repair: Endochondral Priming Enhances Vascularization and New Bone Formation in a Critical Size Defect
Q97528518A Novel 3D Osteoblast and Osteocyte Model Revealing Changes in Mineralization and Pro-osteoclastogenic Paracrine Signaling During Estrogen Deficiency
Q47776404A coupled diffusion-fluid pressure model to predict cell density distribution for cells encapsulated in a porous hydrogel scaffold under mechanical loading
Q36767931A fluid-structure interaction model to characterize bone cell stimulation in parallel-plate flow chamber systems.
Q36023747A model for the role of integrins in flow induced mechanotransduction in osteocytes
Q84279743A three-scale finite element investigation into the effects of tissue mineralisation and lamellar organisation in human cortical and trabecular bone
Q96168974Administration of Human Non-Diabetic Mesenchymal Stromal Cells to a Murine Model of Diabetic Fracture Repair: A Pilot Study
Q93208366Alterations in osteocyte mediated osteoclastogenesis during estrogen deficiency and under ROCK-II inhibition: An in vitro study using a novel postmenopausal multicellular niche model
Q48204171Altered architecture and cell populations affect bone marrow mechanobiology in the osteoporotic human femur
Q35333544Altered mechanical environment of bone cells in an animal model of short- and long-term osteoporosis.
Q51835112An Experimental and Computational Investigation of Bone Formation in Mechanically Loaded Trabecular Bone Explants.
Q46282248An in vitro bone tissue regeneration strategy combining chondrogenic and vascular priming enhances the mineralization potential of mesenchymal stem cells in vitro while also allowing for vessel formation
Q53578266An in vitro evaluation of the impact of eccentric deployment on transcatheter aortic valve hemodynamics.
Q58117095An in vitro model quantifying the effect of calcification on the tissue-stent interaction in a stenosed aortic root
Q43994605Are all osteocytes equal? Multiscale modelling of cortical bone to characterise the mechanical stimulation of osteocytes.
Q33817347Attachment of osteocyte cell processes to the bone matrix
Q38252467Biomimetic approaches in bone tissue engineering: Integrating biological and physicomechanical strategies.
Q90153610Bone Mineral Is More Heterogeneously Distributed in the Femoral Heads of Osteoporotic and Diabetic Patients: A Pilot Study
Q38940248Bone cell mechanosensation of fluid flow stimulation: a fluid-structure interaction model characterising the role integrin attachments and primary cilia
Q37113961Bone mechanical properties and changes with osteoporosis
Q51141355Bone remodelling algorithms incorporating both strain and microdamage stimuli.
Q53560550Bone tissue material properties are altered during osteoporosis.
Q35314068Cell morphology and focal adhesion location alters internal cell stress
Q98281267Comparison of Surgical Smoke Generated During Electrosurgery with Aerosolized Particulates from Ultrasonic and High-Speed Cutting
Q36767954Comparison of in vitro human endothelial cell response to self-expanding stent deployment in a straight and curved peripheral artery simulator
Q44036544Computational modelling of the mechanics of trabecular bone and marrow using fluid structure interaction techniques.
Q89615749Dielectric characterization of diseased human trabecular bones at microwave frequency
Q53235967Differential β3 and β1 Integrin Expression in Bone Marrow and Cortical Bone of Estrogen Deficient Rats.
Q45170732Effects of ageing, prolonged estrogen deficiency and zoledronate on bone tissue mineral distribution.
Q36255294Effects of in vitro endochondral priming and pre-vascularisation of human MSC cellular aggregates in vivo.
Q48967555Endochondral Priming: A Developmental Engineering Strategy for Bone Tissue Regeneration
Q57879608Estrogen Plus Estrogen Receptor Antagonists Alter Mineral Production by Osteoblasts In Vitro
Q50937405Estrogen deficiency attenuates fluid flow-induced [Ca2+]i oscillations and mechanoresponsiveness of MLO-Y4 osteocytes.
Q64091103Estrogen deficiency impairs integrin αβ-mediated mechanosensation by osteocytes and alters osteoclastogenic paracrine signalling
Q39436028Estrogen plus estrogen receptor antagonists alter mineral production by osteoblasts in vitro
Q35085829Estrogen withdrawal from osteoblasts and osteocytes causes increased mineralization and apoptosis
Q86560614Fluid flow in the osteocyte mechanical environment: a fluid-structure interaction approach
Q36348524Heat-shock-induced cellular responses to temperature elevations occurring during orthopaedic cutting.
Q46286331How bone tissue and cells experience elevated temperatures during orthopaedic cutting: an experimental and computational investigation
Q47737787In silico study of bone tissue regeneration in an idealised porous hydrogel scaffold using a mechano-regulation algorithm
Q93094774Integrins in Osteocyte Biology and Mechanotransduction
Q53405782Investigating the interplay between substrate stiffness and ligand chemistry in directing mesenchymal stem cell differentiation within 3D macro-porous substrates.
Q34901255Investigation of the optimal timing for chondrogenic priming of MSCs to enhance osteogenic differentiation in vitro as a bone tissue engineering strategy.
Q35581420Loss of trabeculae by mechano-biological means may explain rapid bone loss in osteoporosis
Q53425321Mechanical stimulation of bone marrow in situ induces bone formation in trabecular explants.
Q104478704Mechanical stimuli and matrix properties modulate cancer spheroid growth in three-dimensional gelatin culture
Q51324538Mechanisms of osteocyte stimulation in osteoporosis.
Q88027172Multiscale fluid-structure interaction modelling to determine the mechanical stimulation of bone cells in a tissue engineered scaffold
Q85896610Multiscale modeling of trabecular bone marrow: understanding the micromechanical environment of mesenchymal stem cells during osteoporosis
Q38863522Osteocyte differentiation and the formation of an interconnected cellular network in vitro.
Q42814254Osteocyte differentiation is regulated by extracellular matrix stiffness and intercellular separation
Q41657953Osteogenic Differentiation of Mesenchymal Stem Cells by Mimicking the Cellular Niche of the Endochondral Template
Q83224587Osteogenic differentiation of mesenchymal stem cells is regulated by osteocyte and osteoblast cells in a simplified bone niche
Q51365785Perforation of cancellous bone trabeculae by damage-stimulated remodelling at resorption pits: a computational analysis.
Q30476509Perspective on post-menopausal osteoporosis: establishing an interdisciplinary understanding of the sequence of events from the molecular level to whole bone fractures
Q94547331Primary Human Osteoblasts Cultured in a 3D Microenvironment Create a Unique Representative Model of Their Differentiation Into Osteocytes
Q49727816Primary cilia exist in a small fraction of cells in trabecular bone and marrow
Q46277301Primary cilia expression in bone marrow in response to mechanical stimulation in explant bioreactor culture
Q51828585Quantification of fluid shear stress in bone tissue engineering scaffolds with spherical and cubical pore architectures.
Q99212438ROCK-II inhibition suppresses impaired mechanobiological responses in early estrogen deficient osteoblasts
Q108214896Shear Stress Within Trabecular Bone Marrow due to Low Magnitude High Frequency Vibration
Q53063421Simulation of self expanding transcatheter aortic valve in a realistic aortic root: implications of deployment geometry on leaflet deformation.
Q57879683Site specific increase in heterogeneity of trabecular bone tissue mineral during oestrogen deficiency
Q41951923Strain amplification and integrin based signaling in osteocytes
Q36188622Strain amplification in bone mechanobiology: a computational investigation of the in vivo mechanics of osteocytes
Q51216511Strength of cancellous bone trabecular tissue from normal, ovariectomized and drug-treated rats over the course of ageing.
Q51281429Stress-concentrating effect of resorption lacunae in trabecular bone.
Q50489065Temporal changes in bone composition, architecture, and strength following estrogen deficiency in osteoporosis
Q50863261The effect of equiaxial stretching on the osteogenic differentiation and mechanical properties of human adipose stem cells.
Q35333586The effect of substrate stiffness, thickness, and cross-linking density on osteogenic cell behavior
Q57879700The effects of estrogen deficiency and bisphosphonate treatment on tissue mineralisation and stiffness in an ovine model of osteoporosis
Q91054912The impact of implantation depth of the Lotus™ valve on mechanical stress in close proximity to the bundle of His
Q85896639The in situ mechanics of trabecular bone marrow: the potential for mechanobiological response
Q45940157The role of adhesion junctions in the biomechanical behaviour and osteogenic differentiation of 3D mesenchymal stem cell spheroids.
Q52655557The role of integrin α(V)β(3) in osteocyte mechanotransduction.
Q35191566Thermally induced osteocyte damage initiates a remodelling signaling cascade.
Q37078423Thermally induced osteocyte damage initiates pro-osteoclastogenic gene expression in vivo
Q36449788Total ellipse of the heart valve: the impact of eccentric stent distortion on the regional dynamic deformation of pericardial tissue leaflets of a transcatheter aortic valve replacement

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