B cell leukemia/lymphoma 6

mammalian protein found in Mus musculus

B cell leukemia/lymphoma 6 is …
instance of (P31):
proteinQ8054

sublass of (P279):
proteinQ8054

External links are
P705Ensembl protein IDENSMUSP00000023151
P637RefSeq protein IDNP_001334955
NP_033874
XP_030104801
P352UniProt protein IDP41183

P682biological processspermatogenesisQ36961
protein localizationQ14599379
negative regulation of cell population proliferationQ14599399
negative regulation of apoptotic processQ14599533
negative regulation of cell growthQ14599698
negative regulation of transcription by RNA polymerase IIQ14633878
regulation of transcription, DNA-templatedQ14633883
negative regulation of transcription, DNA-templatedQ14633919
transcription, DNA-templatedQ14763010
negative regulation of Notch signaling pathwayQ14903090
regulation of GTPase activityQ14906012
negative regulation of cellular senescenceQ14906419
negative regulation of type 2 immune responseQ14907231
germinal center formationQ14907863
immune system processQ14916317
negative regulation of Rho protein signal transductionQ21097200
negative regulation of T-helper 2 cell differentiationQ21108715
regulation of memory T cell differentiationQ21116344
cellular response to DNA damage stimulusQ14818018
positive regulation of histone deacetylationQ14818048
positive regulation of apoptotic processQ14818063
regulation of cell population proliferationQ14818120
inflammatory responseQ14819849
positive regulation of neuron differentiationQ14852017
regulation of transcription by RNA polymerase IIQ14852032
negative regulation of cell differentiationQ14859959
Rho protein signal transductionQ14860470
regulation of inflammatory responseQ14860518
positive regulation of B cell proliferationQ14863401
cell morphogenesisQ14863448
B cell differentiationQ14863499
type 2 immune responseQ14864453
positive regulation of regulatory T cell differentiationQ14864508
negative regulation of isotype switching to IgE isotypesQ14865647
actin cytoskeleton organizationQ14873990
erythrocyte developmentQ14877642
negative regulation of mast cell cytokine productionQ14882889
negative regulation of cell-matrix adhesionQ14889734
P681cell componentnucleusQ40260
Golgi apparatusQ83181
nucleoplasmQ14817956
replication forkQ14817957
P702encoded byBcl6Q18247948
P703found in taxonhouse mouseQ83310
P527has part(s)BTB/POZ domainQ24771346
Zinc finger C2H2-typeQ24785163
P680molecular functionprotein bindingQ167149
metal ion bindingQ13667380
DNA bindingQ14633858
identical protein bindingQ14762994
DNA-binding transcription repressor activity, RNA polymerase II-specificQ21097436
intronic transcription regulatory region sequence-specific DNA bindingQ21109006
chromatin bindingQ14817976
DNA-binding transcription factor activityQ14817979
sequence-specific DNA bindingQ14818107
RNA polymerase II transcription regulatory region sequence-specific DNA bindingQ14864823
nucleic acid bindingQ14864825
chromatin DNA bindingQ14880772
P361part ofSKP1/BTB/POZ domain superfamilyQ24783694
Zinc finger C2H2 superfamilyQ41797357
BTB/POZ domain, protein familyQ83140245
Zinc finger C2H2-type, protein familyQ83164179

Reverse relations

main subject (P921)
Q28590762A BCL6/BCOR/SIRT1 complex triggers neurogenesis and suppresses medulloblastoma by repressing Sonic Hedgehog signaling
Q28593152A negative feedback loop mediated by the Bcl6-cullin 3 complex limits Tfh cell differentiation
Q24300928A putative silencer element in the IL-5 gene recognized by Bcl6
Q28590572ADAR1 protein induces adenosine-targeted DNA mutations in senescent Bcl6 gene-deficient cells
Q28510841Abnormal erythroid differentiation in neonatal bcl-6-deficient mice
Q24522565BAZF, a novel Bcl6 homolog, functions as a transcriptional repressor
Q28585786BCL-6 negatively regulates expression of the NF-kappaB1 p105/p50 subunit
Q28590809BCL-6 negatively regulates macrophage proliferation by suppressing autocrine IL-6 production
Q28513511BCL-6-deficient mice reveal an IL-4-independent, STAT6-dependent pathway that controls susceptibility to infection by Leishmania major
Q28591152BCL6 controls neurogenesis through Sirt1-dependent epigenetic repression of selective Notch targets
Q28586885BCL6 suppresses RhoA activity to alter macrophage morphology and motility
Q28511156Bcl6 acts as an amplifier for the generation and proliferative capacity of central memory CD8+ T cells
Q28592364Bcl6 controls granzyme B expression in effector CD8+ T cells
Q28504587Bcl6 is a transcriptional repressor for the IL-18 gene
Q28587093Bcl6 regulates Th2 type cytokine productions by mast cells activated by FcepsilonRI/IgE cross-linking
Q28585541Control of inflammation, cytokine expression, and germinal center formation by BCL-6
Q28511315Direct repression of prdm1 by Bcl-6 inhibits plasmacytic differentiation
Q28509600Disruption of the Bcl6 gene results in an impaired germinal center formation
Q28595063Evidence from the generation of immunoglobulin G-secreting cells that stochastic mechanisms regulate lymphocyte differentiation
Q28594272FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas
Q28594529Inhibition of Th2 differentiation and GATA-3 expression by BCL-6
Q28510456Memory B cells without somatic hypermutation are generated from Bcl6-deficient B cells
Q28508595Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile
Q28593586Repression of an interleukin-4-responsive promoter requires cooperative BCL-6 function
Q28509583Testicular germ cell apoptosis in Bcl6-deficient mice
Q28509972The ARF tumor suppressor inhibits BCL6-mediated transcriptional repression
Q28584806The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
Q28589662The proto-oncogene Bc16 inhibits apoptotic cell death in differentiation-induced mouse myogenic cells
Q24554404Transcriptional repression of Stat6-dependent interleukin-4-induced genes by BCL-6: specific regulation of iepsilon transcription and immunoglobulin E switching

Q18247948Bcl6encodesP688

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