Chondroitin and glucosamine sulfate in combination decrease the pro-resorptive properties of human osteoarthritis subchondral bone osteoblasts: a basic science study

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Chondroitin and glucosamine sulfate in combination decrease the pro-resorptive properties of human osteoarthritis subchondral bone osteoblasts: a basic science study is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1034862845
P356DOI10.1186/AR2325
P932PMC publication ID2246236
P698PubMed publication ID17996099
P5875ResearchGate publication ID5850986

P50authorJean-Pierre PelletierQ1266067
Johanne Martel-PelletierQ1697061
Daniel LajeunesseQ88426712
Hassan FahmiQ89553792
Steeve Kwan TatQ114415033
Eulàlia MontellQ114415034
P2093author name stringMartin Lavigne
Josep Vergés
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Structural and symptomatic efficacy of glucosamine and chondroitin in knee osteoarthritis: a comprehensive meta-analysisQ34214244
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Glucosamine modulates IL-1-induced activation of rat chondrocytes at a receptor level, and by inhibiting the NF-kappa B pathwayQ34520479
Glucosamine sulfate modulates the levels of aggrecan and matrix metalloproteinase-3 synthesized by cultured human osteoarthritis articular chondrocytesQ34534426
Naturocetic (glucosamine and chondroitin sulfate) compounds as structure-modifying drugs in the treatment of osteoarthritisQ34536828
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Recent advances in glucosamine and chondroitin supplementationQ35955977
RANK, RANKL and osteoprotegerin in arthritic bone lossQ36078073
The efficacy of glucosamine and chondroitin sulfate in the treatment of osteoarthritis: are these saccharides drugs or nutraceuticals?Q36260594
Can altered production of interleukin-1beta, interleukin-6, transforming growth factor-beta and prostaglandin E(2) by isolated human subchondral osteoblasts identify two subgroups of osteoarthritic patientsQ38288322
Transforming growth factor beta affects osteoclast differentiation via direct and indirect actions.Q38296222
Characterization of osteoprotegerin binding to glycosaminoglycans by surface plasmon resonance: role in the interactions with receptor activator of nuclear factor kappaB ligand (RANKL) and RANK.Q38311660
Modulation of insulin-like growth factor 1 levels in human osteoarthritic subchondral bone osteoblastsQ38319364
Regulation of osteoprotegerin mRNA levels by prostaglandin E2 in human bone marrow stroma cellsQ38336153
Human adult chondrocytes express hepatocyte growth factor (HGF) isoforms but not HgF: potential implication of osteoblasts on the presence of HGF in cartilageQ38353421
Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism AssociationQ39513001
The differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor kappaB ligand (RANKL) in human osteoarthritic subchondral bone osteoblasts is an indicator of the metabolic state of these disease cellsQ39970700
OPG/membranous--RANKL complex is internalized via the clathrin pathway before a lysosomal and a proteasomal degradationQ40271933
Human trabecular bone-derived osteoblasts support human osteoclast formation in vitro in a defined, serum-free medium.Q40486045
Transforming growth factor-beta induces osteoclast formation in the absence of RANKL.Q40594156
TGF-beta enhances osteoclast differentiation in hematopoietic cell cultures stimulated with RANKL and M-CSF.Q40919705
Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokinesQ41000781
Osteoprotegerin mRNA is increased by interleukin-1 alpha in the human osteosarcoma cell line MG-63 and in human osteoblast-like cellsQ41016610
Osteoblast-like cells from human subchondral osteoarthritic bone demonstrate an altered phenotype in vitro: possible role in subchondral bone sclerosisQ42455211
Differential gene expression and regulation of the bone morphogenetic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblastsQ42466726
Osteocalcin synthesis by human osteoblasts from normal and osteoarthritic bone after vitamin D3 stimulationQ42476279
Abnormal regulation of urokinase plasminogen activator by insulin-like growth factor 1 in human osteoarthritic subchondral osteoblastsQ42478841
Changing RANKL/OPG mRNA expression in differentiating murine primary osteoblastsQ42507953
Differential regulation of Cbfa1/Runx2 and osteocalcin gene expression by vitamin-D3, dexamethasone, and local growth factors in primary human osteoblastsQ44059999
Study of the role of leukotriene B()4 in abnormal function of human subchondral osteoarthritis osteoblasts: effects of cyclooxygenase and/or 5-lipoxygenase inhibitionQ44068955
In vitro differentiation of embryonic stem cells into mineralized osteoblastsQ44296965
Glucosamine inhibits IL-1beta-induced NFkappaB activation in human osteoarthritic chondrocytesQ44394411
Glucosamine and chondroitin sulfate: biological response modifiers of chondrocytes under simulated conditions of joint stressQ44439622
Modulation of native chondroitin sulphate structure in tissue development and in diseaseQ44706510
Effects of 1,25-dihydroxyvitamin D3 on the expressions of osteoprotegerin and receptor activator of NF-kappaB ligand in mouse osteoblastsQ45066891
Osteoclast differentiation factor acts as a multifunctional regulator in murine osteoclast differentiation and function.Q53768934
1,25-Dihydroxyvitamin D(3) and prostaglandin E(2) act directly on circulating human osteoclast precursorsQ73101643
Evidence for increased bone resorption in patients with progressive knee osteoarthritis: longitudinal results from the Chingford studyQ78667350
Normal human osteoclasts formed from peripheral blood monocytes express PTH type 1 receptors and are stimulated by PTH in the absence of osteoblastsQ81424526
Subchondral bone sclerosis in osteoarthritis: not just an innocent bystanderQ87030169
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectosteoarthritisQ62736
osteoblastQ917177
glucosamineQ32907954
P304page(s)R117
P577publication date2007-01-01
P1433published inArthritis Research and TherapyQ15757229
P1476titleChondroitin and glucosamine sulfate in combination decrease the pro-resorptive properties of human osteoarthritis subchondral bone osteoblasts: a basic science study
P478volume9

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