| scholarly article | Q13442814 |
| P50 | author | Oliver Ottmann | Q39749891 |
| Steffen Koschmieder | Q49505610 | ||
| P2093 | author name string | N Koyama | |
| K Ballas | |||
| D Hoelzer | |||
| G Bug | |||
| W K Hofmann | |||
| S Koschmieder | |||
| U Kalina | |||
| D Kauschat | |||
| H Nuernberger | |||
| P2860 | cites work | Cloning of a novel receptor subunit, AcPL, required for interleukin-18 signaling | Q22004163 |
| Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response | Q22008772 | ||
| The NF-kappa B and I kappa B proteins: new discoveries and insights | Q24313579 | ||
| Purification and characterization of the human interleukin-18 receptor | Q24316885 | ||
| Interferon-gamma-inducing factor enhances T helper 1 cytokine production by stimulated human T cells: synergism with interleukin-12 for interferon-gamma production | Q24317305 | ||
| IRAK: a kinase associated with the interleukin-1 receptor | Q24322162 | ||
| The interleukin-1 receptor accessory protein (IL-1RAcP) is essential for IL-1-induced activation of interleukin-1 receptor-associated kinase (IRAK) and stress-activated protein kinases (SAP kinases) | Q24336458 | ||
| IL-1Rrp is a novel receptor-like molecule similar to the type I interleukin-1 receptor and its homologues T1/ST2 and IL-1R AcP | Q28278375 | ||
| Cloning of a new cytokine that induces IFN-gamma production by T cells | Q28283928 | ||
| Interleukin-1 signal transduction | Q28284071 | ||
| TRAF6 is a signal transducer for interleukin-1 | Q28291934 | ||
| MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1 | Q28302936 | ||
| Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme | Q28610362 | ||
| Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15 | Q28610814 | ||
| Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficient mice | Q30322144 | ||
| Control of lytic function by mitogen-activated protein kinase/extracellular regulatory kinase 2 (ERK2) in a human natural killer cell line: identification of perforin and granzyme B mobilization by functional ERK2. | Q30442814 | ||
| Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells | Q34388169 | ||
| Endotoxin-induced serum factor that stimulates gamma interferon production | Q35091068 | ||
| Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes | Q36356764 | ||
| Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4 | Q36364774 | ||
| The role of natural killer cells in immune surveillance of cancer | Q40952521 | ||
| Binding of interleukin-18 to the interleukin-1 receptor homologous receptor IL-1Rrp1 leads to activation of signaling pathways similar to those used by interleukin-1. | Q40983501 | ||
| STAT3 is a serine kinase target in T lymphocytes. Interleukin 2 and T cell antigen receptor signals converge upon serine 727. | Q41090036 | ||
| NF-kappa B activation by interleukin-1 (IL-1) requires an IL-1 receptor-associated protein kinase activity. | Q46032491 | ||
| Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production | Q50335883 | ||
| Interleukin-18 activates NF-kappaB in murine T helper type 1 cells | Q73401336 | ||
| Interleukin-18 induces activation and association of p56(lck) and MAPK in a murine TH1 clone | Q73614761 | ||
| Comparison of the effects of interleukin-1 alpha, interleukin-1 beta and interferon-gamma-inducing factor on the production of interferon-gamma by natural killer | Q73933704 | ||
| Interleukin-18 activates the IRAK-TRAF6 pathway in mouse EL-4 cells | Q74353084 | ||
| IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 family | Q77807763 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cytotoxicity | Q246181 |
| Interleukin 18 | Q2657109 | ||
| positive regulation of tyrosine phosphorylation of STAT protein | Q14907233 | ||
| P304 | page(s) | 1307-1313 | |
| P577 | publication date | 2000-08-01 | |
| P1433 | published in | Journal of Immunology | Q3521441 |
| P1476 | title | IL-18 activates STAT3 in the natural killer cell line 92, augments cytotoxic activity, and mediates IFN-gamma production by the stress kinase p38 and by the extracellular regulated kinases p44erk-1 and p42erk-21 | |
| P478 | volume | 165 |
| Q24291492 | A novel role for interleukin-18 in adhesion molecule induction through NF kappa B and phosphatidylinositol (PI) 3-kinase-dependent signal transduction pathways |
| Q33434284 | A phase I, open-label, dose-escalation, multicenter study of the JAK2 inhibitor NS-018 in patients with myelofibrosis |
| Q28661722 | Alu mobile elements: from junk DNA to genomic gems |
| Q39662381 | Change of mouse CD5(+) B1 cells to a macrophage-like morphology induced by gamma interferon and inhibited by interleukin-4. |
| Q50027343 | Clinical grade manufacturing of genetically modified, CAR-expressing NK-92 cells for the treatment of ErbB2-positive malignancies |
| Q46430408 | Daily administration of interleukin-18 causes myocardial dysfunction in healthy mice |
| Q83864443 | Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance |
| Q36187269 | ERK1/2 activation is a therapeutic target in age-related macular degeneration. |
| Q36820322 | ERK1/2, MEK1/2 and p38 downstream signalling molecules impaired in CD56 dim CD16+ and CD56 bright CD16 dim/- natural killer cells in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients |
| Q89725115 | Emerging Roles for Interleukin-18 in the Gastrointestinal Tumor Microenvironment |
| Q35189080 | Endogenous interleukin 18 suppresses hyperglycemia and hyperinsulinemia during the acute phase of endotoxemia in mice. |
| Q24803546 | Expression of interleukin-18 receptor in fibroblast-like synoviocytes |
| Q35027238 | From extracellular to intracellular targets, inhibiting MAP kinases in treatment of Crohn's disease |
| Q30635371 | Genomic organization and regulation of the human interleukin-18 gene |
| Q24321583 | HLA class I molecules regulate IFN-gamma production induced in NK cells by target cells, viral products, or immature dendritic cells through the inhibitory receptor ILT2/CD85j |
| Q40090748 | Hemojuvelin regulates the innate immune response to peritoneal bacterial infection in mice |
| Q34582210 | Highly pathogenic avian influenza virus infection in chickens but not ducks is associated with elevated host immune and pro-inflammatory responses |
| Q37362940 | IL-18 and IL-33 elicit Th2 cytokines from basophils via a MyD88- and p38alpha-dependent pathway |
| Q38124723 | IL-18 in inflammatory and autoimmune disease |
| Q35013368 | IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation |
| Q79851916 | IL-18 time-dependently modulates Th1/Th2 cytokine production by ligand-activated NKT cells |
| Q38837671 | IL-18-induced interaction between IMP3 and HuR contributes to COX-2 mRNA stabilization in acute myeloid leukemia |
| Q24307467 | IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response |
| Q38292971 | Identification of amino acid residues critical for biological activity in human interleukin-18. |
| Q42099571 | Implication of interleukin 18 in production of matrix metalloproteinases in articular chondrocytes in arthritis: direct effect on chondrocytes may not be pivotal |
| Q54372515 | Interleukin 18 activates MAPKs and STAT3 but not NF-κB in hippocampal HT-22 cells. |
| Q34095673 | Interleukin 18 in the CNS. |
| Q44762073 | Interleukin-18 enhances monocyte tumor necrosis factor alpha and interleukin-1beta production induced by direct contact with T lymphocytes: implications in rheumatoid arthritis. |
| Q64275741 | Interleukin-18 in Health and Disease |
| Q90630396 | Interleukin-18 levels in the hippocampus and behavior of adult rat offspring exposed to prenatal restraint stress during early and late pregnancy |
| Q35103096 | Interleukin-18 promotes joint inflammation and induces interleukin-1-driven cartilage destruction |
| Q81681379 | Interleukin-18 resistance in patients with obesity and type 2 diabetes mellitus |
| Q30884172 | Interleukin-18. |
| Q47285927 | Interleukin-18: Biological properties and role in disease pathogenesis |
| Q46572704 | Involvement of inflammation, degradation, and apoptosis in a mouse model of glaucoma |
| Q34987949 | Jaks, STATs, Cytokines, and Sepsis |
| Q35541393 | Limited response of NK92 cells to Plasmodium falciparum-infected erythrocytes |
| Q48226767 | Low expression of IL-18 and IL-18 receptor in human skeletal muscle is associated with systemic and intramuscular lipid metabolism-Role of HIV lipodystrophy |
| Q42909598 | Mycobacterium tuberculosis-induced gamma interferon production by natural killer cells requires cross talk with antigen-presenting cells involving Toll-like receptors 2 and 4 and the mannose receptor in tuberculous pleurisy |
| Q39865381 | Potential role of interleukin-18 in the immunopathogenesis of AIDS: involvement in fratricidal killing of NK cells |
| Q38812169 | Regulation of IFN-γ Expression |
| Q51756481 | Retinal ganglion cell protection by 17-beta-estradiol in a mouse model of inherited glaucoma. |
| Q38402599 | Role of interleukin-18 in modulation of oral carcinoma cell proliferation |
| Q39579469 | Signal transducer and activator of transcription 3 (STAT3) and Suppressor of Cytokine Signaling (SOCS3) balance controls cytotoxicity and IL-10 expression in decidual-like natural killer cell line NK-92. |
| Q42523343 | Signal transduction pathways involved in rheumatoid arthritis synovial fibroblast interleukin-18-induced vascular cell adhesion molecule-1 expression |
| Q37210723 | Stat4-dependent, T-bet-independent regulation of IL-10 in NK cells |
| Q43647235 | TGF beta-induced SMAD2 phosphorylation predicts inhibition of thymidine incorporation in CD34+ cells from healthy donors, but not from patients with AML after MDS. |
| Q40673759 | TGFbeta down-regulates IFN-gamma production in IL-18 treated NK cell line LNK5E6. |
| Q40116692 | The Fc Domain of Immunoglobulin Is Sufficient to Bridge NK Cells with Virally Infected Cells |
| Q36229017 | The PP2A inhibitor SET regulates natural killer cell IFN-gamma production |
| Q42918546 | The inflammasome in alcoholic hepatitis: Its relationship with Mallory-Denk body formation |
| Q34142278 | The synergy between stem cell factor (SCF) and granulocyte colony-stimulating factor (G-CSF): molecular basis and clinical relevance |
| Q38233046 | Utilizing cytokines to function-enable human NK cells for the immunotherapy of cancer |
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