| scholarly article | Q13442814 |
| P356 | DOI | 10.3171/FOC/2008/24/3-4/E8 |
| P698 | PubMed publication ID | 18341412 |
| P50 | author | Roger A. Barker | Q60589802 |
| P2093 | author name string | Colin Watts | |
| Claire D. Clelland | |||
| P2860 | cites work | Neural stem cells improve memory in an inducible mouse model of neuronal loss. | Q44339825 |
| Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: a PET study. | Q44400030 | ||
| Survival and differentiation of adult rat-derived neural progenitor cells transplanted to the striatum of hemiparkinsonian rats. | Q44614362 | ||
| Striatal neural grafting improves cortical metabolism in Huntington's disease patients | Q44649029 | ||
| Adult-born hippocampal neurons mature into activity-dependent responsiveness | Q44680391 | ||
| Brain-derived neurotrophic factor-mediated protection of striatal neurons in an excitotoxic rat model of Huntington's disease, as demonstrated by adenoviral gene transfer | Q44694208 | ||
| Long-term lentiviral-mediated expression of ciliary neurotrophic factor in the striatum of Huntington's disease transgenic mice | Q44707365 | ||
| Effects of Sertoli cell transplants in a 3-nitropropionic acid model of early Huntington's disease: a preliminary study | Q44722641 | ||
| Decreased hippocampal cell proliferation in R6/1 Huntington's mice. | Q44836981 | ||
| Neurogenesis in the striatum of the quinolinic acid lesion model of Huntington's disease. | Q44985302 | ||
| Cell types, lineage, and architecture of the germinal zone in the adult dentate gyrus | Q45071634 | ||
| Autologous adult bone marrow stem cell transplantation in an animal model of huntington's disease: behavioral and morphological outcomes | Q45289644 | ||
| Excitotoxin lesions in primates as a model for Huntington's disease: histopathologic and neurochemical characterization | Q45291026 | ||
| Long-term hibernation of human fetal striatal tissue does not adversely affect its differentiation in vitro or graft survival: implications for clinical trials in Huntington's disease. | Q45291840 | ||
| Paucity of P-zones in striatal grafts prohibit commencement of clinical trials in Huntington's disease | Q45293120 | ||
| Early striatal dendrite deficits followed by neuron loss with advanced age in the absence of anterograde cortical brain-derived neurotrophic factor. | Q45293425 | ||
| Neuropsychological functioning following fetal striatal transplantation in Huntington's chorea: three case presentations | Q45294365 | ||
| Safety of Intrastriatal Neurotransplantation for Huntington's Disease Patients | Q45295583 | ||
| Fetal striatal allografts reverse cognitive deficits in a primate model of Huntington disease | Q45296323 | ||
| The distribution of progenitor cells in the subependymal layer of the lateral ventricle in the normal and Huntington's disease human brain | Q45296613 | ||
| Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice. | Q45296827 | ||
| Striatal transplantation in a transgenic mouse model of Huntington's disease | Q45297047 | ||
| Neuropathological classification of Huntington's disease | Q45297167 | ||
| Progressive loss of BDNF in a mouse model of Huntington's disease and rescue by BDNF delivery | Q45297213 | ||
| Positron emission tomography after fetal transplantation in Huntington's disease | Q45297853 | ||
| Asialoerythropoietin is not effective in the R6/2 line of Huntington's disease mice | Q24795623 | ||
| A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. | Q27860836 | ||
| Induction of neurogenesis in the neocortex of adult mice | Q28139868 | ||
| Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease | Q28202050 | ||
| Autoradiographic and histological studies of postnatal neurogenesis. IV. Cell proliferation and migration in the anterior forebrain, with special reference to persisting neurogenesis in the olfactory bulb | Q28252251 | ||
| Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats | Q28256786 | ||
| Neurogenesis in the adult human hippocampus | Q28288339 | ||
| Corticostriatopallidal neuroprotection by adenovirus-mediated ciliary neurotrophic factor gene transfer in a rat model of progressive striatal degeneration | Q28581577 | ||
| Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease | Q28588314 | ||
| Human Neuroblasts Migrate to the Olfactory Bulb via a Lateral Ventricular Extension | Q29027476 | ||
| Running enhances neurogenesis, learning, and long-term potentiation in mice | Q29391363 | ||
| Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants | Q29547516 | ||
| Neuronal replacement from endogenous precursors in the adult brain after stroke | Q29615772 | ||
| Adult neurogenesis in the mammalian central nervous system | Q29618706 | ||
| Functional neurogenesis in the adult hippocampus | Q29618708 | ||
| Vascular niche for adult hippocampal neurogenesis | Q29619395 | ||
| Wnt signalling regulates adult hippocampal neurogenesis | Q29619688 | ||
| Neurogenesis in the adult is involved in the formation of trace memories | Q29622890 | ||
| Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington disease | Q30480065 | ||
| Grafted neural stem cells develop into functional pyramidal neurons and integrate into host cortical circuitry | Q30873232 | ||
| Unilateral transplantation of human primary fetal tissue in four patients with Huntington's disease: NEST-UK safety report ISRCTN no 36485475. | Q31118947 | ||
| Training specificity, graft development and graft-mediated functional recovery in a rodent model of Huntington's disease. | Q31160848 | ||
| Expression of brain-derived neurotrophic factor in cortical neurons is regulated by striatal target area. | Q31813509 | ||
| Motor training effects on recovery of function after striatal lesions and striatal grafts. | Q33195323 | ||
| Environmental enrichment affects striatal graft morphology and functional recovery. | Q33197252 | ||
| Reduced hippocampal neurogenesis in R6/2 transgenic Huntington's disease mice | Q33216927 | ||
| Learning enhances adult neurogenesis in the hippocampal formation | Q33858060 | ||
| Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism. | Q33976362 | ||
| Effect of fetal neural transplants in patients with Huntington's disease 6 years after surgery: a long-term follow-up study | Q33994217 | ||
| Embryonic striatal grafts restore neuronal activity of the globus pallidus in a rodent model of Huntington's disease | Q45298059 | ||
| A histochemical and immunohistochemical analysis of the subependymal layer in the normal and Huntington's disease brain | Q45298137 | ||
| In vivo magnetic resonance spectroscopy of human fetal neural transplants | Q45298655 | ||
| Cognitive disorders and neurogenesis deficits in Huntington's disease mice are rescued by fluoxetine. | Q45298962 | ||
| Neural progenitor implantation restores metabolic deficits in the brain following striatal quinolinic acid lesion | Q45299179 | ||
| Safety and tolerability assessment of intrastriatal neural allografts in five patients with Huntington's disease | Q45299926 | ||
| Delaying the onset of Huntington's in mice | Q45300228 | ||
| Survival, neuronal differentiation, and fiber outgrowth of propagated human neural precursor grafts in an animal model of Huntington's disease. | Q45300235 | ||
| Embryonic donor age and dissection influences striatal graft development and functional integration in a rodent model of Huntington's disease | Q45300246 | ||
| Neurogenesis in the R6/1 transgenic mouse model of Huntington's disease: effects of environmental enrichment | Q45300776 | ||
| Transplanted adult neural progenitor cells survive, differentiate and reduce motor function impairment in a rodent model of Huntington's disease. | Q45300810 | ||
| Differential effects of voluntary physical exercise on behavioral and brain-derived neurotrophic factor expression deficits in Huntington's disease transgenic mice. | Q45301264 | ||
| Motor and cognitive improvements in patients with Huntington's disease after neural transplantation | Q45301920 | ||
| Time of transplantation and cell preparation determine neural stem cell survival in a mouse model of Huntington's disease | Q45302681 | ||
| Anterior cingulate cortical transplantation in transgenic Huntington’s disease mice | Q45304732 | ||
| Neural transplantation in Huntington disease: long-term grafts in two patients | Q45305355 | ||
| Bilateral human fetal striatal transplantation in Huntington's disease. | Q45305502 | ||
| Fetal neural grafts for Huntington's disease: a prospective view | Q45306436 | ||
| Neural stem cells from adult hippocampus develop essential properties of functional CNS neurons | Q46123186 | ||
| Adult spinal cord stem cells generate neurons after transplantation in the adult dentate gyrus. | Q46175129 | ||
| Increased Neurogenesis in the Dentate Gyrus After Transient Global Ischemia in Gerbils | Q46341741 | ||
| FGF-2-responsive neuronal progenitors reside in proliferative and quiescent regions of the adult rodent brain | Q46496054 | ||
| Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo | Q46556773 | ||
| Becoming a new neuron in the adult olfactory bulb | Q48330854 | ||
| Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients with Parkinson's disease | Q48405897 | ||
| Influence of mesostriatal afferents on the development and transmitter regulation of intrastriatal grafts derived from embryonic striatal primordia | Q48418058 | ||
| Huntington disease | Q48465200 | ||
| Functional integration of adult-born neurons. | Q48637283 | ||
| Direct evidence for homotypic, glia-independent neuronal migration | Q48714438 | ||
| Neurotrophin responsiveness is differentially regulated in neurons and precursors isolated from the developing striatum. | Q48737383 | ||
| Growth factors regulate the survival and fate of cells derived from human neurospheres. | Q48895258 | ||
| Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell | Q49011276 | ||
| Chain migration of neuronal precursors. | Q49115425 | ||
| Granule-like neurons at the hilar/CA3 border after status epilepticus and their synchrony with area CA3 pyramidal cells: functional implications of seizure-induced neurogenesis. | Q52166176 | ||
| Trophic and protective actions of brain-derived neurotrophic factor on striatal DARPP-32-containing neurons in vitro | Q54154873 | ||
| Time course of the neuroprotective effect of transplantation on quinolinic acid-induced lesions of the striatum | Q71095106 | ||
| Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid | Q72098398 | ||
| The neurotrophins BDNF, NT-3 and NT-4/5 promote survival and morphological and biochemical differentiation of striatal neurons in vitro | Q72254050 | ||
| Neurodegeneration: a failure of neuroregeneration? | Q40681977 | ||
| Excitatory amino acids differentially regulate the expression of GDNF, neurturin, and their receptors in the adult rat striatum | Q40741337 | ||
| Neuroprotection through delivery of glial cell line-derived neurotrophic factor by neural stem cells in a mouse model of Parkinson's disease. | Q40776566 | ||
| Neuroprotection of striatal neurons against kainate excitotoxicity by neurotrophins and GDNF family members | Q40777710 | ||
| Huntington's disease progression. PET and clinical observations. | Q40787958 | ||
| Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 prevent the death of striatal projection neurons in a rodent model of Huntington's disease | Q40826187 | ||
| Restoration of cognitive and motor functions by ciliary neurotrophic factor in a primate model of Huntington's disease. | Q40876522 | ||
| Cellular Delivery of Cntf but not Nt-4/5 Prevents Degeneration of Striatal Neurons in a Rodent Model of Huntington's Disease | Q41042641 | ||
| Glial cell line-derived neurotrophic factor attenuates the excitotoxin-induced behavioral and neurochemical deficits in a rodent model of Huntington's disease | Q41087697 | ||
| Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease | Q41120174 | ||
| Glial cell line-derived neurotrophic factor protects striatal calbindin-immunoreactive neurons from excitotoxic damage | Q41154059 | ||
| Implants of encapsulated human CNTF-producing fibroblasts prevent behavioral deficits and striatal degeneration in a rodent model of Huntington's disease | Q41175238 | ||
| Embryonic stem cells differentiated in vitro as a novel source of cells for transplantation | Q41222340 | ||
| Co-localization of brain-derived neurotrophic factor (BDNF) and wild-type huntingtin in normal and quinolinic acid-lesioned rat brain | Q42447105 | ||
| Mature intrastriatal striatal grafts revert the changes in the expression of pallidal and thalamic alpha 1, alpha 2 and beta 2/3 GABAA receptor subunit induced by ibotenic acid lesions in the rat striatum | Q42458621 | ||
| Human neural stem cell transplants improve motor function in a rat model of Huntington's disease | Q42463574 | ||
| Transplanted xenogeneic neural cells in neurodegenerative disease models exhibit remarkable axonal target specificity and distinct growth patterns of glial and axonal fibres. | Q42479352 | ||
| Abnormalities of neurogenesis in the R6/2 mouse model of Huntington's disease are attributable to the in vivo microenvironment. | Q42488000 | ||
| Characterization of GABA release from intrastriatal striatal transplants: dependence on host-derived afferents | Q42497672 | ||
| Functional integration of striatal allografts in a primate model of Huntington's disease. | Q42541733 | ||
| Neuroprotective effect of a CNTF-expressing lentiviral vector in the quinolinic acid rat model of Huntington's disease. | Q43665724 | ||
| N-methyl-D-aspartate receptor-mediated increase of neurogenesis in adult rat dentate gyrus following stroke | Q43698114 | ||
| Prolonged seizures increase proliferating neuroblasts in the adult rat subventricular zone-olfactory bulb pathway. | Q43954506 | ||
| Neural cells from primary human striatal xenografts migrate extensively in the adult rat CNS. | Q43975392 | ||
| Astroglia induce neurogenesis from adult neural stem cells | Q43977940 | ||
| The adult substantia nigra contains progenitor cells with neurogenic potential. | Q44085183 | ||
| Dose-dependent neuroprotective effect of ciliary neurotrophic factor delivered via tetracycline-regulated lentiviral vectors in the quinolinic acid rat model of Huntington's disease. | Q44213139 | ||
| FGF-2 promotes neurogenesis and neuroprotection and prolongs survival in a transgenic mouse model of Huntington's disease | Q34212651 | ||
| Isolation, Characterization, and use of Stem Cells from the CNS | Q34299470 | ||
| Dopamine depletion impairs precursor cell proliferation in Parkinson disease. | Q34326801 | ||
| Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus | Q34424431 | ||
| The influence of environment and experience on neural grafts. | Q34457234 | ||
| Identification of a neural stem cell in the adult mammalian central nervous system | Q34492720 | ||
| Viral delivery of glial cell line-derived neurotrophic factor improves behavior and protects striatal neurons in a mouse model of Huntington's disease | Q34695123 | ||
| Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration | Q34706597 | ||
| Astrocytes and brain injury | Q35061615 | ||
| Recent advances in stem cell neurobiology | Q35081927 | ||
| Increased cell proliferation and neurogenesis in the adult human Huntington's disease brain | Q35171498 | ||
| Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease | Q35176635 | ||
| Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat | Q35298897 | ||
| Differences in duration of Huntington's disease based on age at onset | Q35449269 | ||
| Transplanted fetal striatum in Huntington's disease: phenotypic development and lack of pathology | Q35579484 | ||
| Neurogenesis in the adult brain: new strategies for central nervous system diseases | Q35639161 | ||
| Pro-regenerative properties of cytokine-activated astrocytes. | Q35775364 | ||
| Pathological cell-cell interactions are necessary for striatal pathogenesis in a conditional mouse model of Huntington's disease | Q35828444 | ||
| Immune problems in central nervous system cell therapy. | Q36045396 | ||
| Ciliary neurotrophic factor protects striatal output neurons in an animal model of Huntington disease | Q37503857 | ||
| Intrastriatal transplantation of cross-species fetal striatal cells reduces abnormal movements in a primate model of Huntington disease | Q37600345 | ||
| Neurogenesis of corticospinal motor neurons extending spinal projections in adult mice | Q37621803 | ||
| Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease | Q39111166 | ||
| Fetal nigral grafts survive and mediate clinical benefit in a patient with Parkinson's disease | Q39116027 | ||
| Influence of lamotrigine on progression of early Huntington disease: a randomized clinical trial | Q39118783 | ||
| Striatal dopaminergic afferents concentrate in GDNF-positive patches during development and in developing intrastriatal striatal grafts. | Q39197001 | ||
| Widespread disruption of repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy at its target genes in Huntington's disease. | Q39333674 | ||
| Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient | Q39434658 | ||
| Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease | Q39519102 | ||
| Neuroprotection by GDNF-secreting stem cells in a Huntington's disease model: optical neuroimage tracking of brain-grafted cells. | Q39767290 | ||
| Human embryonic stem cell-derived neural precursor transplants attenuate apomorphine-induced rotational behavior in rats with unilateral quinolinic acid lesions | Q40099462 | ||
| Neural cell adhesion molecule L1-transfected embryonic stem cells promote functional recovery after excitotoxic lesion of the mouse striatum. | Q40210558 | ||
| Embryonic stem cell-derived neuronally committed precursor cells with reduced teratoma formation after transplantation into the lesioned adult mouse brain | Q40321092 | ||
| Neuroprotective gene therapy for Huntington's disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: results of a phase I study. | Q40462605 | ||
| Neuroprotective effects of encapsulated CNTF-producing cells in a rodent model of Huntington's disease are dependent on the proximity of the implant to the lesioned striatum | Q40546909 | ||
| Transplanted hNT cells ("LBS neurons") in a rat model of huntington's disease: good survival, incomplete differentiation, and limited functional recovery. | Q40558612 | ||
| Evidence for more widespread cerebral pathology in early HD: an MRI-based morphometric analysis | Q40585913 | ||
| Structural and functional neuroprotection in a rat model of Huntington's disease by viral gene transfer of GDNF. | Q40643169 | ||
| Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury | Q40643190 | ||
| Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease. | Q40661429 | ||
| P433 | issue | 3-4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Huntington's disease | Q190564 |
| P304 | page(s) | E9 | |
| P577 | publication date | 2008-03-01 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Neurosurgical Focus | Q15759894 |
| P1476 | title | Cell therapy in Huntington disease | |
| P478 | volume | 24 |
| Q24317631 | Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice |
| Q42289973 | CRISPR-Cas9 Mediated Gene-Silencing of the Mutant Huntingtin Gene in an In Vitro Model of Huntington's Disease |
| Q38697315 | Clinical translation of stem cells in neurodegenerative disorders. |
| Q38999340 | Current Perspective of Stem Cell Therapy in Neurodegenerative and Metabolic Diseases |
| Q48463371 | Effective induction of cells expressing GABAergic neuronal markers from mouse embryonic stem cell. |
| Q35473934 | Effects of histocompatibility and host immune responses on the tumorigenicity of pluripotent stem cells |
| Q34404822 | Elucidating the Sources of β-Catenin Dynamics in Human Neural Progenitor Cells |
| Q37488273 | Emerging drug therapies in Huntington's disease |
| Q88008795 | Human Umbilical Cord Matrix Stem Cells Reverse Oxidative Stress-Induced Cell Death and Ameliorate Motor Function and Striatal Atrophy in Rat Model of Huntington Disease |
| Q30512860 | Human embryonic stem cell-derived GABA neurons correct locomotion deficits in quinolinic acid-lesioned mice. |
| Q38102294 | Huntington's disease in children |
| Q45295396 | Implant-supported overdenture in an elderly patient with Huntington's disease |
| Q45305883 | Induced Pluripotent Stem Cell-Derived Neural Stem Cell Transplantations Reduced Behavioral Deficits and Ameliorated Neuropathological Changes in YAC128 Mouse Model of Huntington's Disease |
| Q37550841 | Investigating Mutations to Reduce Huntingtin Aggregation by Increasing Htt-N-Terminal Stability and Weakening Interactions with PolyQ Domain |
| Q38066117 | Neural stem cells—trends and advances |
| Q64912813 | Novel targets for Huntington's disease: future prospects. |
| Q39497356 | Quantitative and kinetic profile of Wnt/β-catenin signaling components during human neural progenitor cell differentiation. |
| Q88431956 | Sertoli Cells Avert Neuroinflammation-Induced Cell Death and Improve Motor Function and Striatal Atrophy in Rat Model of Huntington Disease |
| Q28544748 | Spatio-temporal model of endogenous ROS and raft-dependent WNT/beta-catenin signaling driving cell fate commitment in human neural progenitor cells |
| Q33614689 | Stem Cells Transplantation and Huntington's Disease |
| Q94186892 | Stem Cells for the Treatment of Neurodegenerative Diseases |
| Q35224202 | Stem cell technology for neurodegenerative diseases. |
| Q37426967 | Transplantation of GABA-producing cells for seizure control in models of temporal lobe epilepsy |
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