| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1996PNAS...93.7346A |
| P356 | DOI | 10.1073/PNAS.93.14.7346 |
| P932 | PMC publication ID | 38987 |
| P698 | PubMed publication ID | 8692996 |
| P5875 | ResearchGate publication ID | 14509253 |
| P2093 | author name string | Wiegand SJ | |
| Anderson KD | |||
| Lindsay RM | |||
| Panayotatos N | |||
| Corcoran TL | |||
| P2860 | cites work | Neurotrophic factors attenuate glutamate-induced accumulation of peroxides, elevation of intracellular Ca2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons | Q71748788 |
| In situ hybridization of trkB and trkC receptor mRNA in rat forebrain and association with high-affinity binding of [125I]BDNF, [125I]NT-4/5 and [125I]NT-3 | Q71986609 | ||
| Arrest of motor neuron disease in wobbler mice cotreated with CNTF and BDNF | Q72142043 | ||
| Quantitative comparison of the transient rescue effects of neurotrophic factors on axotomized motoneurons in vivo | Q72145001 | ||
| Neurotrophic factor receptors and their signal transduction capabilities in rat astrocytes | Q72162022 | ||
| Brain-derived neurotrophic factor promotes differentiation of striatal GABAergic neurons | Q72194700 | ||
| The neurotrophins BDNF, NT-3 and NT-4/5 promote survival and morphological and biochemical differentiation of striatal neurons in vitro | Q72254050 | ||
| Basic fibroblast growth factor protects against excitotoxicity and chemical hypoxia in both neonatal and adult rats | Q72333921 | ||
| Brain-derived neurotrophic factor is a survival factor for cultured rat cerebellar granule neurons and protects them against glutamate-induced neurotoxicity | Q72664326 | ||
| Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF | Q24310580 | ||
| A role for ciliary neurotrophic factor as an inducer of reactive gliosis, the glial response to central nervous system injury | Q24563422 | ||
| GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle | Q28241629 | ||
| Recombinant human and rat ciliary neurotrophic factors | Q28286502 | ||
| Effects of striatal excitotoxicity on huntingtin-like immunoreactivity | Q28507359 | ||
| The alpha component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development | Q28573544 | ||
| Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy | Q29397966 | ||
| The functional anatomy of basal ganglia disorders | Q29617461 | ||
| Glutamate neurotoxicity and diseases of the nervous system | Q34560997 | ||
| Intravenous administration of a transferrin receptor antibody-nerve growth factor conjugate prevents the degeneration of cholinergic striatal neurons in a model of Huntington disease | Q35761924 | ||
| Ciliary neurotrophic factor prevents degeneration of adult rat substantia nigra dopaminergic neurons in vivo | Q36406386 | ||
| Normal and expanded Huntington's disease gene alleles produce distinguishable proteins due to translation across the CAG repeat. | Q36437616 | ||
| Neurotransmitters and neuromodulators in the basal ganglia | Q36586002 | ||
| Excitotoxic injury of the neostriatum: a model for Huntington's disease | Q36586040 | ||
| Effect of ciliary neurotrophic factor (CNTF) on motoneuron survival. | Q37074159 | ||
| Neurotrophic factors: from molecule to man. | Q40391603 | ||
| Genetics and molecular biology of Huntington's disease | Q40399297 | ||
| In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons | Q41379191 | ||
| Implantation of polymer-encapsulated human nerve growth factor-secreting fibroblasts attenuates the behavioral and neuropathological consequences of quinolinic acid injections into rodent striatum | Q41433526 | ||
| Effects of biologically delivered NGF, BDNF and bFGF on striatal excitotoxic lesions | Q41564204 | ||
| Neuroprotective strategies in a model of chronic glutamate-mediated motor neuron toxicity | Q41676626 | ||
| Differential distribution of exogenous BDNF, NGF, and NT‐3 in the brain corresponds to the relative abundance and distribution of high‐affinity and low‐affinity neurotrophin receptors | Q42482319 | ||
| High-affinity nerve growth factor receptor (Trk) immunoreactivity is localized in cholinergic neurons of the basal forebrain and striatum in the adult rat brain | Q42505736 | ||
| Widespread expression of Huntington's disease gene (IT15) protein product | Q42684112 | ||
| Huntington's disease gene: regional and cellular expression in brain of normal and affected individuals | Q45288801 | ||
| Relative survival of striatal projection neurons and interneurons after intrastriatal injection of quinolinic acid in rats | Q45289092 | ||
| Intrastriatal infusion of nerve growth factor after quinolinic acid prevents reduction of cellular expression of choline acetyltransferase messenger RNA and trkA messenger RNA, but not glutamate decarboxylase messenger RNA. | Q45289297 | ||
| Transcription of the Huntington disease gene during the quinolinic acid excitotoxic cascade | Q45307565 | ||
| Ciliary neurotrophic factor prevents neuronal degeneration and promotes low affinity NGF receptor expression in the adult rat CNS | Q46188017 | ||
| Protection of the rat retina from ischemic injury by brain-derived neurotrophic factor, ciliary neurotrophic factor, and basic fibroblast growth factor. | Q46227481 | ||
| Nerve growth factor and basic fibroblast growth factor protect cholinergic neurons against quinolinic acid excitotoxicity in rat neostriatum | Q48129261 | ||
| NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults | Q48155678 | ||
| Basic fibroblast growth factor protects against hypoxia-ischemia and NMDA neurotoxicity in neonatal rats | Q48324531 | ||
| Nerve growth factor selectively prevents excitotoxin induced degeneration of striatal cholinergic neurones | Q48468082 | ||
| Dimeric structure and conformational stability of brain-derived neurotrophic factor and neurotrophin-3. | Q48480955 | ||
| Effects of quinolinic acid on messenger RNAs encoding somatostatin and glutamic acid decarboxylases in the striatum of adult rats | Q48543270 | ||
| Nigrostriatal pathway modulates striatum vulnerability to quinolinic acid | Q48639396 | ||
| Ciliary neurotrophic factor prevents ischemia-induced learning disability and neuronal loss in gerbils | Q52208349 | ||
| Brain-derived neurotrophic factor pretreatment exerts a partially protective effect against glutamate-induced neurotoxicity in cultured rat cortical neurons | Q58413294 | ||
| Exchange of a single amino acid interconverts the specific activity and gel mobility of human and rat ciliary neurotrophic factors | Q70472172 | ||
| P433 | issue | 14 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Huntington's disease | Q190564 |
| striatum | Q1319792 | ||
| P304 | page(s) | 7346-7351 | |
| P577 | publication date | 1996-07-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Ciliary neurotrophic factor protects striatal output neurons in an animal model of Huntington disease | |
| P478 | volume | 93 |
| Q22004019 | A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia |
| Q40560840 | AAV-mediated gene delivery of BDNF or GDNF is neuroprotective in a model of Huntington disease |
| Q34305677 | Activation of BMP-Smad1/5/8 Signaling Promotes Survival of Retinal Ganglion Cells after Damage In Vivo |
| Q48115865 | Activation of astrocytes by CNTF induces metabolic plasticity and increases resistance to metabolic insults. |
| Q45298550 | Administration of recombinant human Activin-A has powerful neurotrophic effects on select striatal phenotypes in the quinolinic acid lesion model of Huntington's disease |
| Q33843043 | Bone Marrow Mesenchymal Stem-Cell Transplantation Promotes Functional Improvement Associated with CNTF-STAT3 Activation after Hemi-Sectioned Spinal Cord Injury in Tree Shrews |
| Q40826187 | Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 prevent the death of striatal projection neurons in a rodent model of Huntington's disease |
| Q24290161 | CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex |
| Q44086440 | CNTF inhibits high voltage activated Ca2+ currents in fetal mouse cortical neurones. |
| Q22305670 | Cell therapy in Huntington disease |
| Q36045364 | Cell therapy in Huntington's disease. |
| Q41042641 | Cellular Delivery of Cntf but not Nt-4/5 Prevents Degeneration of Striatal Neurons in a Rodent Model of Huntington's Disease |
| Q34353562 | Chorea and its disorders |
| Q28573797 | Ciliary Neurotrophic Factor Activates Spinal Cord Astrocytes, Stimulating Their Production and Release of Fibroblast Growth Factor-2, to Increase Motor Neuron Survival |
| Q48515330 | Ciliary neurotrophic factor activates astrocytes, redistributes their glutamate transporters GLAST and GLT-1 to raft microdomains, and improves glutamate handling in vivo. |
| Q28144767 | Ciliary neurotrophic factor and stress stimuli activate the Jak-STAT pathway in retinal neurons and glia |
| Q48137369 | Ciliary neurotrophic factor enhances the expression of NGF and p75 low-affinity NGF receptor in astrocytes |
| Q48165100 | Ciliary neurotrophic factor protects hippocampal neurons from excitotoxic damage |
| Q33559739 | Ciliary neurotrophic factor protects striatal neurons against excitotoxicity by enhancing glial glutamate uptake |
| Q61444124 | Ciliary neurotrophic factor stimulates cardioprotection and the proliferative activity in the adult zebrafish heart |
| Q35221952 | Continued administration of ciliary neurotrophic factor protects mice from inflammatory pathology in experimental autoimmune encephalomyelitis. |
| Q28581577 | Corticostriatopallidal neuroprotection by adenovirus-mediated ciliary neurotrophic factor gene transfer in a rat model of progressive striatal degeneration |
| Q41104867 | Differential susceptibility to neurotoxicity mediated by neurotrophins and neuronal nitric oxide synthase. |
| Q39428788 | Exploring the potential of natural and synthetic neuroprotective steroids against neurodegenerative disorders: A literature review. |
| Q40647866 | GFAP knockout mice have increased levels of GDNF that protect striatal neurons from metabolic and excitotoxic insults |
| Q40070708 | Gene Therapy in the Nervous System: Failures and Successes. |
| Q44319940 | Gene expression profiling of ciliary neurotrophic factor-overexpressing rat striatal progenitor cells (ST14A) indicates improved stress response during the early stage of differentiation |
| Q37973607 | Gene therapy for Huntington's disease |
| Q41087697 | Glial cell line-derived neurotrophic factor attenuates the excitotoxin-induced behavioral and neurochemical deficits in a rodent model of Huntington's disease |
| Q41063077 | Glial cell line-derived neurotrophic factor attenuates the locomotor hypofunction and striatonigral neurochemical deficits induced by chronic systemic administration of the mitochondrial toxin 3-nitropropionic acid |
| Q82993834 | Huntington's Disease |
| Q35158643 | Huntington's Disease: From Mutant Huntingtin Protein to Neurotrophic Factor Therapy |
| Q73229472 | Impact of a preceding striatal excitotoxic lesion and treatment with ciliary neurotrophic factor on striatal graft survival |
| Q74272717 | In vivo localization and characterization of functional ciliary neurotrophic factor receptors which utilize JAK-STAT signaling |
| Q42512642 | Intracerebral infusion of a second-generation ciliary neurotrophic factor reduces neuronal loss in rat striatum following experimental intracerebral hemorrhage |
| Q34019665 | Intranasal delivery of neurotrophic factors BDNF, CNTF, EPO, and NT-4 to the CNS. |
| Q37265519 | Large animal models of neurological disorders for gene therapy |
| Q39319510 | Loss of Neuron-Astroglial Interaction Rapidly Induces Protective CNTF Expression after Stroke in Mice |
| Q48368565 | NT-3, but not BDNF, prevents atrophy and death of axotomized spinal cord projection neurons |
| Q43892580 | Neuroprotective effect of interleukin-6 and IL6/IL6R chimera in the quinolinic acid rat model of Huntington's syndrome |
| Q36519737 | Neurotrophic enhancers as therapy for behavioral deficits in rodent models of Huntington's disease: use of gangliosides, substituted pyrimidines, and mesenchymal stem cells |
| Q35618345 | Neurotrophic factors in Huntington's disease |
| Q36654492 | Neurotrophic factors in neurodegeneration. |
| Q40873179 | Neurturin protects striatal projection neurons but not interneurons in a rat model of Huntington's disease |
| Q40582623 | Nucleic Acid-Based Therapy Approaches for Huntington's Disease |
| Q37355436 | P2X7 receptor inhibition increases CNTF in the subventricular zone, but not neurogenesis or neuroprotection after stroke in adult mice |
| Q48628421 | Phenotypic Alteration of Astrocytes Induced by Ciliary Neurotrophic Factor in the Intact Adult Brain, As Revealed by Adenovirus-Mediated Gene Transfer |
| Q43239575 | Progesterone, BDNF and neuroprotection in the injured CNS. |
| Q44400030 | Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: a PET study. |
| Q41120174 | Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease |
| Q44828223 | Quinolinic acid lesions of the caudate putamen in the rat lead to a local increase of ciliary neurotrophic factor. |
| Q30322247 | Receptor recognition sites of cytokines are organized as exchangeable modules. Transfer of the leukemia inhibitory factor receptor-binding site from ciliary neurotrophic factor to interleukin-6. |
| Q45303980 | Recombinant AAV Viral Vectors Serotype 1, 2, and 5 Mediate Differential Gene Transfer Efficiency in Rat Striatal Fetal Grafts |
| Q48291009 | Regulation of neuronal nitric oxide synthase and identification of novel nitric oxide signaling pathways |
| Q48227541 | Regulation of nociceptin/orphanin FQ gene expression by neuropoietic cytokines and neurotrophic factors in neurons and astrocytes |
| Q52168280 | STAT signalling in the mature and aging brain |
| Q46844274 | STAT3 activation in photoreceptors by leukemia inhibitory factor is associated with protection from light damage |
| Q24297991 | Signaling of human ciliary neurotrophic factor (CNTF) revisited. The interleukin-6 receptor can serve as an alpha-receptor for CTNF |
| Q41055614 | Synergistic but transient rescue effects of BDNF and GDNF on axotomized neonatal motoneurons |
| Q41847430 | The amino acid exchange R28E in ciliary neurotrophic factor (CNTF) abrogates interleukin-6 receptor-dependent but retains CNTF receptor-dependent signaling via glycoprotein 130 (gp130)/leukemia inhibitory factor receptor (LIFR). |
| Q28144474 | The ciliary neurotrophic factor and its receptor, CNTFR alpha |
| Q74697359 | The role of neuronal growth factors in neurodegenerative disorders of the human brain |
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