scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0079-6123(03)46014-7 |
P698 | PubMed publication ID | 14699966 |
P2093 | author name string | Jordi Alberch | |
Josep M Canals | |||
Esther Pérez-Navarro | |||
P2860 | cites work | Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex | Q22008642 |
Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi | Q24292161 | ||
The receptor for ciliary neurotrophic factor | Q24305006 | ||
Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF | Q24310580 | ||
A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor | Q24311883 | ||
Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth | Q24313379 | ||
GFRα3 is an orphan member of the GDNF/neurturin/persephin receptor family | Q24313994 | ||
Molecular cloning, expression and tissue distribution of glial‐cell‐line‐derived neurotrophic factor family receptor α‐3 (GFRα‐3) | Q24315361 | ||
Persephin, a novel neurotrophic factor related to GDNF and neurturin | Q24315831 | ||
Neurturin, a relative of glial-cell-line-derived neurotrophic factor | Q24324692 | ||
GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF | Q24329169 | ||
GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons | Q24336322 | ||
Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR | Q24533555 | ||
Effects of cerebral ischemia in mice deficient in Persephin | Q24534911 | ||
The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway. | Q24540169 | ||
GFRα1 Is an Essential Receptor Component for GDNF in the Developing Nervous System and Kidney | Q24649094 | ||
Neurotrophins: roles in neuronal development and function | Q24656166 | ||
Expression and regulation of GFRalpha3, a glial cell line-derived neurotrophic factor family receptor | Q24682581 | ||
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. | Q27860836 | ||
Neurotrophin signal transduction in the nervous system | Q27876223 | ||
A Kinase Insert Isoform of Rat TrkA Supports Nerve Growth Factor‐Dependent Cell Survival but Not Neurite Outgrowth | Q73664236 | ||
Differential regulation of ciliary neurotrophic factor and its receptor in the rat hippocampus following transient global ischemia | Q73666003 | ||
Is the therapeutic application of neurotrophic factors dead? | Q77466542 | ||
Expression of neurturin, GDNF, and GDNF family-receptor mRNA in the developing and mature mouse | Q28140328 | ||
The ciliary neurotrophic factor and its receptor, CNTFR alpha | Q28144474 | ||
In vivo protection of nigral dopamine neurons by lentiviral gene transfer of the novel GDNF-family member neublastin/artemin | Q28144676 | ||
The GDNF family ligands and receptors - implications for neural development | Q28144957 | ||
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease | Q28202050 | ||
The GDNF family: signalling, biological functions and therapeutic value | Q28216478 | ||
Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors | Q28235378 | ||
The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain | Q28238459 | ||
GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle | Q28241629 | ||
trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor | Q28273781 | ||
Neurturin Exerts Potent Actions on Survival and Function of Midbrain Dopaminergic Neurons | Q28274311 | ||
Neurotrophin-3: a neurotrophic factor related to NGF and BDNF | Q28280663 | ||
A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences | Q28282360 | ||
Neurotrophin-4: the odd one out in the neurotrophin family | Q28293752 | ||
The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor | Q28295368 | ||
Naturally Occurring Tyrosine Kinase Inserts Block High Affinity Binding of Phospholipase Cγ and Shc to TrkC and Neurotrophin-3 Signaling | Q28296382 | ||
Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells | Q28297730 | ||
trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3 | Q28301898 | ||
Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes | Q28302701 | ||
Human trks: molecular cloning, tissue distribution, and expression of extracellular domain immunoadhesins | Q28305583 | ||
Ciliary neurotrophic factor | Q28307184 | ||
Inactivation of the mouse Huntington's disease gene homolog Hdh | Q28509662 | ||
Identification and Characterization of GFRα-3, a Novel Co-receptor Belonging to the Glial Cell Line-derived Neurotrophic Receptor Family | Q28513903 | ||
Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor | Q28572533 | ||
Mammalian GFRalpha -4, a divergent member of the GFRalpha family of coreceptors for glial cell line-derived neurotrophic factor family ligands, is a receptor for the neurotrophic factor persephin | Q28577124 | ||
Corticostriatopallidal neuroprotection by adenovirus-mediated ciliary neurotrophic factor gene transfer in a rat model of progressive striatal degeneration | Q28581577 | ||
Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons | Q28584797 | ||
Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease | Q28588314 | ||
Changes in Cortical and Striatal Neurons Predict Behavioral and Electrophysiological Abnormalities in a Transgenic Murine Model of Huntington's Disease | Q28589793 | ||
The trk proto-oncogene encodes a receptor for nerve growth factor | Q28609788 | ||
The trk Proto-Oncogene Product: a Signal Transducing Receptor for Nerve Growth Factor | Q28609789 | ||
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice | Q29615357 | ||
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain | Q29617982 | ||
Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development. | Q30488256 | ||
Ciliary neurotrophic factor coordinately activates transcription of neuropeptide genes in a neuroblastoma cell line | Q36061465 | ||
The neostriatal mosaic: multiple levels of compartmental organization in the basal ganglia | Q36064948 | ||
Ciliary neurotrophic factor prevents retrograde neuronal death in the adult central nervous system | Q36161670 | ||
Ciliary neurotrophic factor corrects obesity and diabetes associated with leptin deficiency and resistance | Q36188464 | ||
Growth of purified astrocytes in a chemically defined medium | Q36380669 | ||
Ciliary neurotrophic factor prevents degeneration of adult rat substantia nigra dopaminergic neurons in vivo | Q36406386 | ||
Differential expression of nerve growth factor receptors leads to altered binding affinity and neurotrophin responsiveness. | Q36493889 | ||
Mammalian neurotrophin-4: structure, chromosomal localization, tissue distribution, and receptor specificity | Q36935698 | ||
Evaluation of nigrostriatal dopaminergic function in adult +/+ and +/- BDNF mutant mice | Q43649918 | ||
Neuroprotective effect of a CNTF-expressing lentiviral vector in the quinolinic acid rat model of Huntington's disease. | Q43665724 | ||
TrkB and TrkC are differentially regulated by excitotoxicity during development of the basal ganglia | Q43804607 | ||
Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease | Q43925468 | ||
Effects of nerve and fibroblast growth factors on the production of nitric oxide in experimental model of Huntington's disease | Q44020174 | ||
Pyramidal cell loss in motor cortices in Huntington's disease | Q44149293 | ||
Persephin-overexpressing neural stem cells regulate the function of nigral dopaminergic neurons and prevent their degeneration in a model of Parkinson's disease | Q44195016 | ||
Ciliary neurotrophic factor supports target-deprived preganglionic sympathetic spinal cord neurons | Q44440163 | ||
Brain-derived neurotrophic factor-mediated protection of striatal neurons in an excitotoxic rat model of Huntington's disease, as demonstrated by adenoviral gene transfer | Q44694208 | ||
Purification, cloning, and expression of ciliary neurotrophic factor (CNTF). | Q45094286 | ||
Degeneration of pyramidal projection neurons in Huntington's disease cortex | Q45294227 | ||
Huntingtin: a single bait hooks many species | Q45296265 | ||
Experimental Therapeutics of Neurodegenerative Disorders: Unmet Needs | Q45296771 | ||
Selective sparing of a class of striatal neurons in Huntington's disease | Q45297134 | ||
Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 after excitotoxicity in a rat model of Huntington's disease | Q45297386 | ||
A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration. | Q45298582 | ||
Intracerebral implantation of NGF-releasing biodegradable microspheres protects striatum against excitotoxic damage | Q45299933 | ||
Brain-derived neurotrophic factor in Huntington disease | Q45300415 | ||
Neuroprotection of nerve growth factor-loaded microspheres on the D2 dopaminergic receptor positive-striatal neurones in quinolinic acid-lesioned rats: a quantitative autoradiographic assessment with iodobenzamide | Q45300665 | ||
Developmental regulation of nerve growth factor and its receptor in the rat caudate-putamen. | Q46030268 | ||
Protective effects of neurotrophin-4/5 and transforming growth factor-alpha on striatal neuronal phenotypic degeneration after excitotoxic lesioning with quinolinic acid | Q46087231 | ||
Maintenance of sympathetic innervation into the hippocampal formation requires a continuous local availability of nerve growth factor | Q46155148 | ||
Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury. | Q46187210 | ||
Ciliary neurotrophic factor prevents neuronal degeneration and promotes low affinity NGF receptor expression in the adult rat CNS | Q46188017 | ||
Stimulation of GABAergic neuron differentiation by NT-4/5 in cultures of rat cerebral cortex | Q46302375 | ||
Developmental and regional expression of beta-nerve growth factor receptor mRNA in the chick and rat. | Q46412140 | ||
Induction of noncatalytic TrkB neurotrophin receptors during axonal sprouting in the adult hippocampus | Q46743236 | ||
Signaling mechanisms through gp130: A model of the cytokine system | Q47992455 | ||
GDNF-related factor persephin is widely distributed throughout the nervous system | Q48028240 | ||
Nerve growth factor and basic fibroblast growth factor protect cholinergic neurons against quinolinic acid excitotoxicity in rat neostriatum | Q48129261 | ||
Requirement for BDNF in activity-dependent survival of cortical neurons | Q48156100 | ||
NGF facilitates the developmental maturation of the previously committed cholinergic interneurons in the striatal matrix | Q48164620 | ||
Increased levels of nerve growth factor (NGF) protein and mRNA and reactive gliosis following kainic acid injection into the rat striatum | Q48171880 | ||
Brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4/5 differentially regulate the phenotype and prevent degenerative changes in striatal projection neurons after excitotoxicity in vivo | Q48172704 | ||
Expression of the striatal DARPP-32/ARPP-21 phenotype in GABAergic neurons requires neurotrophins in vivo and in vitro. | Q48181177 | ||
The neurotrophin receptors trkA, trkB and trkC are differentially regulated after excitotoxic lesion in rat striatum. | Q48188055 | ||
Overlapping and distinct actions of the neurotrophins BDNF, NT-3, and NT-4/5 on cultured dopaminergic and GABAergic neurons of the ventral mesencephalon. | Q48196753 | ||
Developmental expression of trkC, the neurotrophin-3 receptor, in the mammalian nervous system. | Q48196786 | ||
Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor | Q48208108 | ||
Cultured hippocampal neurons show responses to BDNF, NT-3, and NT-4, but not NGF | Q48245956 | ||
Widespread and developmentally regulated expression of neurotrophin-4 mRNA in rat brain and peripheral tissues | Q48278654 | ||
Intrastriatal grafting of a GDNF-producing cell line protects striatonigral neurons from quinolinic acid excitotoxicity in vivo | Q48284526 | ||
Expression of members of the trk family in the developing postnatal rat brain | Q48319176 | ||
Rat fetal ventral mesencephalon grown as solid tissue cultures: influence of culture time and BDNF treatment on dopamine neuron survival and function | Q48337282 | ||
Age-related changes in levels of brain-derived neurotrophic factor in selected brain regions of rats, normal mice and senescence-accelerated mice: a comparison to those of nerve growth factor and neurotrophin-3. | Q48353958 | ||
Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. | Q48373564 | ||
Injury-induced regulation of ciliary neurotrophic factor mRNA in the adult rat brain | Q48379221 | ||
Nerve growth factor selectively prevents excitotoxin induced degeneration of striatal cholinergic neurones | Q48468082 | ||
Distribution of the neurotrophins brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 in the postnatal rat brain: an immunocytochemical study | Q48498182 | ||
Anterograde transport of brain-derived neurotrophic factor and its role in the brain | Q48539947 | ||
Ciliary neurotrophic factor protects striatal output neurons in an animal model of Huntington disease | Q37503857 | ||
Nerve growth factor promotes cholinergic development in brain striatal cultures | Q37556010 | ||
Preferential loss of preproenkephalin versus preprotachykinin neurons from the striatum of Huntington's disease patients | Q38288534 | ||
Localization of GDNF/neurturin receptor (c-ret, GFRalpha-1 and alpha-2) mRNAs in postnatal rat brain: differential regional and temporal expression in hippocampus, cortex and cerebellum | Q38317887 | ||
Striatal dopaminergic afferents concentrate in GDNF-positive patches during development and in developing intrastriatal striatal grafts. | Q39197001 | ||
Huntington's disease. Pathogenesis and management | Q39460676 | ||
Protein kinase B activation and lamellipodium formation are independent phosphoinositide 3-kinase-mediated events differentially regulated by endogenous Ras. | Q39630940 | ||
The nerve growth factor 35 years later | Q39667849 | ||
Development of effective therapy for Alzheimer's disease based on neurotrophic factors | Q40496632 | ||
The p75 neurotrophin receptor | Q40590902 | ||
The Trk family of neurotrophin receptors | Q40590908 | ||
The tripartite CNTF receptor complex: activation and signaling involves components shared with other cytokines | Q40590933 | ||
Neurochemistry and toxin models in Huntington's disease. | Q40599311 | ||
Oxidative stress, glutamate, and neurodegenerative disorders | Q40618533 | ||
Glial cell line neurotrophic factor-family receptor alpha-1 is present in central neurons with distinct phenotypes | Q40676299 | ||
Ciliary neurotrophic factor (CNTF) enhances myelin formation: a novel role for CNTF and CNTF-related molecules. | Q40692097 | ||
Regulation of c-Ret, GFRalpha1, and GFRalpha2 in the substantia nigra pars compacta in a rat model of Parkinson's disease | Q40706788 | ||
Neurturin is a neuritogenic but not a survival factor for developing and adult central noradrenergic neurons | Q40724503 | ||
Excitatory amino acids differentially regulate the expression of GDNF, neurturin, and their receptors in the adult rat striatum | Q40741337 | ||
Striatopallidal neurons are selectively protected by neurturin in an excitotoxic model of Huntington's disease | Q40744948 | ||
Novel mechanism of regulation of Rac activity and lamellipodia formation by RET tyrosine kinase | Q40745449 | ||
GFRα‐1 mRNA in dopaminergic and nondopaminergic neurons in the substantia nigra and ventral tegmental area | Q40763041 | ||
Functions of the neurotrophins during nervous system development: what the knockouts are teaching us. | Q40763660 | ||
Brain-derived neurotrophic factor (BDNF) mediates bone morphogenetic protein-2 (BMP-2) effects on cultured striatal neurones | Q40766507 | ||
Coordinated activation of autophosphorylation sites in the RET receptor tyrosine kinase: importance of tyrosine 1062 for GDNF mediated neuronal differentiation and survival | Q40768044 | ||
Neuroprotection through delivery of glial cell line-derived neurotrophic factor by neural stem cells in a mouse model of Parkinson's disease. | Q40776566 | ||
Neuroprotection of striatal neurons against kainate excitotoxicity by neurotrophins and GDNF family members | Q40777710 | ||
Compartmental expression of trkB receptor protein in the developing striatum | Q40821499 | ||
Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 prevent the death of striatal projection neurons in a rodent model of Huntington's disease | Q40826187 | ||
Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease | Q40846012 | ||
Immunohistochemical localization of glial cell line-derived neurotrophic factor in the human central nervous system | Q40848213 | ||
Determinants of ligand binding specificity in the glial cell line-derived neurotrophic factor family receptor alpha S. | Q40851328 | ||
GDNF enhances the synaptic efficacy of dopaminergic neurons in culture | Q40853630 | ||
Neuroprotective gene therapy for Huntington's disease using a polymer encapsulated BHK cell line engineered to secrete human CNTF. | Q40859352 | ||
Reactive astrocytes of the quinolinic acid-lesioned rat striatum express GFRalpha1 as well as GDNF in vivo | Q40870366 | ||
Neurturin protects striatal projection neurons but not interneurons in a rat model of Huntington's disease | Q40873179 | ||
Restoration of cognitive and motor functions by ciliary neurotrophic factor in a primate model of Huntington's disease. | Q40876522 | ||
Wild-type huntingtin protects from apoptosis upstream of caspase-3. | Q40880907 | ||
GDNF triggers a novel ret-independent Src kinase family-coupled signaling via a GPI-linked GDNF receptor alpha1. | Q40911466 | ||
Preclinical testing of neuroprotective neurotrophic factors in a model of chronic motor neuron degeneration | Q40922137 | ||
Ret-dependent and -independent mechanisms of glial cell line-derived neurotrophic factor signaling in neuronal cells | Q40941497 | ||
Differential effects of glial cell line-derived neurotrophic factor and neurturin on developing and adult substantia nigra dopaminergic neurons | Q40945102 | ||
Neuroprotective utility and neurotrophic action of neurturin in postnatal motor neurons: comparison with GDNF and persephin | Q40950872 | ||
Effects of BDNF on dopaminergic, serotonergic, and GABAergic neurons in cultures of human fetal ventral mesencephalon. | Q40987702 | ||
GFRα-4 and the tyrosine kinase Ret form a functional receptor complex for persephin | Q41008328 | ||
Expression of neurturin, GDNF, and their receptors in the adult mouse CNS | Q41016790 | ||
Expression of GDNF Family Receptor Components during Development: Implications in the Mechanisms of Interaction | Q41036193 | ||
Localization of glial cell line-derived neurotrophic factor receptor alpha and c-ret mRNA in rat central nervous system | Q41053776 | ||
Glial cell line-derived neurotrophic factor attenuates the locomotor hypofunction and striatonigral neurochemical deficits induced by chronic systemic administration of the mitochondrial toxin 3-nitropropionic acid | Q41063077 | ||
Glial cell line-derived neurotrophic factor attenuates the excitotoxin-induced behavioral and neurochemical deficits in a rodent model of Huntington's disease | Q41087697 | ||
Cellular and developmental patterns of expression of Ret and glial cell line-derived neurotrophic factor receptor alpha mRNAs | Q41100969 | ||
Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase. | Q41105131 | ||
Signal transduction mediated by the truncated trkB receptor isoforms, trkB.T1 and trkB.T2. | Q41116074 | ||
Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease | Q41120174 | ||
Neuronal GDNF expression in the adult rat nervous system identified by in situ hybridization | Q41123196 | ||
Intracellular signaling pathways activated by neurotrophic factors | Q41132714 | ||
The neurotrophins and CNTF: two families of collaborative neurotrophic factors | Q41132721 | ||
Dose-dependent responses to nerve growth factor by adult rat cholinergic medial septum and neostriatum neurons | Q41149174 | ||
Glial cell line-derived neurotrophic factor protects striatal calbindin-immunoreactive neurons from excitotoxic damage | Q41154059 | ||
Glial-cell-line-derived neurotrophic factor enhances biosynthesis of substance P in striatal neurons in vitro | Q41156909 | ||
Cellular expression of GDNF mRNA suggests multiple functions inside and outside the nervous system | Q41156961 | ||
Effects of GDNF on fetal septal forebrain transplants in oculo | Q41165513 | ||
Implants of encapsulated human CNTF-producing fibroblasts prevent behavioral deficits and striatal degeneration in a rodent model of Huntington's disease | Q41175238 | ||
Protection of the neostriatum against excitotoxic damage by neurotrophin-producing, genetically modified neural stem cells | Q41180628 | ||
Functional receptor for GDNF encoded by the c-ret proto-oncogene | Q41190489 | ||
Expression of the trk proto-oncogene is restricted to the sensory cranial and spinal ganglia of neural crest origin in mouse development | Q41236657 | ||
Choline acetyltransferase activity in striatum of neonatal rats increased by nerve growth factor | Q41340059 | ||
Regulation of voltage-gated ion channels by NGF and ciliary neurotrophic factor in SK-N-SH neuroblastoma cells | Q41404665 | ||
Neurotrophins and activity-dependent plasticity of cortical interneurons | Q41462642 | ||
Nerve growth factor gene expression in the developing rat brain | Q41474843 | ||
Effects of biologically delivered NGF, BDNF and bFGF on striatal excitotoxic lesions | Q41564204 | ||
Ciliary neurotrophic factor induces cholinergic differentiation of rat sympathetic neurons in culture | Q41576201 | ||
Blood-brain barrier penetration and in vivo activity of an NGF conjugate | Q41578400 | ||
The trkB tyrosine protein kinase is a receptor for neurotrophin-4 | Q41626768 | ||
Cholinergic neuronotrophic factors: intraocular distribution of trophic activity for ciliary neurons | Q41652949 | ||
Neurotrophin-5: A novel neurotrophic factor that activates trk and trkB | Q41658559 | ||
The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3. | Q41674996 | ||
High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor | Q41687095 | ||
Intracerebral implantation of nerve growth factor-producing fibroblasts protects striatum against neurotoxic levels of excitatory amino acids | Q41704517 | ||
Phenotypic Alteration of Astrocytes Induced by Ciliary Neurotrophic Factor in the Intact Adult Brain, As Revealed by Adenovirus-Mediated Gene Transfer | Q48628421 | ||
Brain-derived neurotrophic factor regulates maturation of the DARPP-32 phenotype in striatal medium spiny neurons: studies in vivo and in vitro | Q48678036 | ||
Cells that Express Brain-Derived Neurotrophic Factor mRNA in the Developing Postnatal Rat Brain | Q48691261 | ||
Opposing roles for endogenous BDNF and NT-3 in regulating cortical dendritic growth. | Q48714447 | ||
Expression of brain-derived neurotrophic factor protein in the adult rat central nervous system | Q48720818 | ||
BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra | Q48767968 | ||
Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines | Q48867473 | ||
Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family | Q48888641 | ||
Immunohistochemical localization of brain-derived neurotrophic factor in adult rat brain | Q48906109 | ||
Cellular expression of ionotropic glutamate receptor subunits on specific striatal neuron types and its implication for striatal vulnerability in glutamate receptor-mediated excitotoxicity | Q48955052 | ||
Delayed death of septal cholinergic neurons after excitotoxic ablation of hippocampal neurons during early postnatal development in the rat. | Q48983239 | ||
Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family | Q49053110 | ||
Intrastriatal and intraventricular infusion of brain-derived neurotrophic factor in the cynomologous monkey: distribution, retrograde transport and co-localization with substantia nigra dopamine-containing neurons | Q49076744 | ||
Differential trophic effects of basic fibroblast growth factor, insulin-like growth factor-1, and neurotrophin-3 on striatal neurons in culture | Q49109125 | ||
The survival of striatal cholinergic neurons cultured from postnatal 2-week-old rats is promoted by neurotrophins | Q49111888 | ||
Spatiotemporal expression of noncatalytic TrkC NC2 isoform during early and late CNS neurogenesis: a comparative study with TrkC catalytic and p75NTR receptors. | Q52165103 | ||
Developmental regulation of BDNF and NT-3 expression by quinolinic acid in the striatum and its main connections | Q52165694 | ||
Truncated and full-length TrkB receptors regulate distinct modes of dendritic growth | Q52169905 | ||
Neural Differentiation Promoted by Truncated trkC Receptors in Collaboration with p75NTR | Q52184656 | ||
Proliferation and differentiation of embryonic chick sympathetic neurons: effects of ciliary neurotrophic factor | Q52247249 | ||
Disruption of the CNTF gene results in motor neuron degeneration | Q52516638 | ||
NMDA receptor subunit mRNA expression by projection neurons and interneurons in rat striatum. | Q54168901 | ||
Potentiation of transmitter release by ciliary neurotrophic factor requires somatic signaling | Q54590336 | ||
Cryptic physiological trophic support of motoneurons by LIF revealed by double gene targeting of CNTF and LIF | Q57198135 | ||
Essential function of LIF receptor in motor neurons | Q59065862 | ||
CNTF is a major protective factor in demyelinating CNS disease: A neurotrophic cytokine as modulator in neuroinflammation | Q60215313 | ||
Endogenous ciliary neurotrophic factor is a lesion factor for axotomized motoneurons in adult mice | Q60215454 | ||
Opposite Regulation of Calbindin and Calretinin Expression by Brain-Derived Neurotrophic Factor in Cortical Neurons | Q61774072 | ||
Control of embryonic motoneuron survival in vivo by ciliary neurotrophic factor | Q70132556 | ||
The molecular biology of the CNTF receptor | Q70458874 | ||
Purification of the chick eye ciliary neuronotrophic factor | Q70650968 | ||
Nerve growth factor protects the neonatal brain against hypoxic-ischemic injury | Q70928177 | ||
The distribution of brain-derived neurotrophic factor and its receptor trkB in parvalbumin-containing neurons of the rat visual cortex | Q71383340 | ||
Changes in neurotrophic factor expression and receptor activation following exposure of hippocampal neuron/astrocyte cocultures to kainic acid | Q71511467 | ||
Up-regulation of trkB mRNA expression in the rat striatum after seizures | Q71526004 | ||
Intrastriatal Infusions of Brain-Derived Neurotrophic Factor: Retrograde Transport and Colocalization with Dopamine Containing Substantia Nigra Neurons in Rat | Q71650088 | ||
Protective Role of Nerve Growth Factor against Excitatory Amino Acid Injury during Neostriatal Cholinergic Neurons Postnatal Development | Q71815652 | ||
Released Form of CNTF Receptor α Component as a Soluble Mediator of CNTF Responses | Q72074174 | ||
Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid | Q72098398 | ||
Arrest of motor neuron disease in wobbler mice cotreated with CNTF and BDNF | Q72142043 | ||
Time course of ciliary neurotrophic factor mRNA expression is coincident with the presence of protoplasmic astrocytes in traumatized rat striatum | Q72151741 | ||
Brain-derived neurotrophic factor promotes differentiation of striatal GABAergic neurons | Q72194700 | ||
The neurotrophins BDNF, NT-3 and NT-4/5 promote survival and morphological and biochemical differentiation of striatal neurons in vitro | Q72254050 | ||
Protective effects of BDNF and NT-3 but not PDGF against hypoglycemic injury to cultured striatal neurons | Q72643375 | ||
Obituary | Q73459586 | ||
Brain-derived neurotrophic factor requirement for activity-dependent maturation of glutamatergic synapse in developing mouse somatosensory cortex | Q73505736 | ||
Expression of nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 in the somatosensory cortex of the mature rat: coexpression with high-affinity neurotrophin receptors | Q73508855 | ||
Expression of brain-derived neurotrophic factor in cortical neurons is regulated by striatal target area. | Q31813509 | ||
GDNF rescues nonpeptidergic unmyelinated primary afferents in streptozotocin-treated diabetic mice | Q31848096 | ||
Differential expression of GDNF, BDNF, and NT-3 in the aging nigrostriatal system following a neurotoxic lesion | Q31873597 | ||
GFRα-4, a New GDNF Family Receptor | Q32058878 | ||
Cloning and characterization of glial cell line-derived neurotrophic factor receptor-B: A novel receptor for members of glial cell line-derived neurotrophic factor family of neurotrophic factors | Q32122155 | ||
trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors | Q33332038 | ||
Neurotrophic factors and diabetic peripheral neuropathy | Q33534157 | ||
Recent advances on the pathogenesis of Huntington's disease | Q33604650 | ||
Differential loss of striatal projection neurons in Huntington disease | Q33637273 | ||
Recent advances in understanding the pathogenesis of Huntington's disease | Q33650539 | ||
p75 neurotrophin receptor as a modulator of survival and death decisions | Q33670585 | ||
Cellular delivery of trophic factors for the treatment of Huntington's disease: is neuroprotection possible? | Q33732493 | ||
Replicating Huntington's disease phenotype in experimental animals | Q33749061 | ||
Neuroprotective strategies for basal ganglia degeneration: Parkinson's and Huntington's diseases | Q33851629 | ||
Glial cell line-derived neurotrophic factor promotes the survival and morphologic differentiation of Purkinje cells | Q33884388 | ||
Released GFRalpha1 potentiates downstream signaling, neuronal survival, and differentiation via a novel mechanism of recruitment of c-Ret to lipid rafts. | Q33933786 | ||
Trk receptors: mediators of neurotrophin action | Q33950703 | ||
The basal ganglia | Q33970931 | ||
Loss of normal huntingtin function: new developments in Huntington's disease research | Q34142361 | ||
Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches | Q34156542 | ||
Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway | Q34278037 | ||
Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene. | Q34338664 | ||
Characterization of a multicomponent receptor for GDNF. | Q34383378 | ||
Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid | Q34384772 | ||
TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret. | Q34428727 | ||
The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3 | Q34497200 | ||
Huntington's disease: new hope for therapeutics | Q34553826 | ||
Neuroprotection by neurotrophins and GDNF family members in the excitotoxic model of Huntington's disease. | Q34657624 | ||
Neurotrophin signaling through the p75 neurotrophin receptor | Q34778209 | ||
Polyglutamine pathogenesis: emergence of unifying mechanisms for Huntington's disease and related disorders | Q34952853 | ||
Spontaneous and neurotrophin-induced axonal plasticity after spinal cord injury | Q35002869 | ||
Intravenous administration of a transferrin receptor antibody-nerve growth factor conjugate prevents the degeneration of cholinergic striatal neurons in a model of Huntington disease | Q35761924 | ||
The epidemiology of Huntington's disease | Q35882166 | ||
An alternatively spliced form of the nerve growth factor receptor TrkA confers an enhanced response to neurotrophin 3. | Q35897889 | ||
Cortical degeneration in the absence of neurotrophin signaling: dendritic retraction and neuronal loss after removal of the receptor TrkB. | Q41734248 | ||
Effects of ciliary neurotrophic factor (CNTF) and depolarization on neuropeptide expression in cultured sympathetic neurons | Q42013685 | ||
A Role for TrkA during Maturation of Striatal and Basal Forebrain Cholinergic NeuronsIn Vivo | Q42444980 | ||
Expression of Brain-Derived Neurotrophic Factor and TrkB Neurotrophin Receptors after Striatal Injury in the Mouse | Q42448123 | ||
Molecular cloning of rat trkC and distribution of cells expressing messenger RNAs for members of the trk family in the rat central nervous system | Q42458072 | ||
p140trk mRNA marks NGF-responsive forebrain neurons: evidence that trk gene expression is induced by NGF | Q42458990 | ||
Differential regulation of the low-affinity nerve growth factor receptor during postnatal development of the rat brain | Q42463884 | ||
Survival of Adult Basal Forebrain Cholinergic Neurons After Loss of Target Neurons | Q42465160 | ||
Cellular localization of brain-derived neurotrophic factor-like immunoreactivity in adult monkey brain | Q42468669 | ||
Two components from eye tissue that differentially stimulate the growth and development of ciliary ganglion neurons in cell culture. | Q42472375 | ||
Destabilization of cortical dendrites and spines by BDNF. | Q42474475 | ||
Neurotrophins regulate dendritic growth in developing visual cortex | Q42479052 | ||
BDNF is needed for postnatal maturation of basal forebrain and neostriatum cholinergic neurons in vivo | Q42485788 | ||
Expression of neurotrophin and trk receptor genes in adult rats with fimbria transections: effect of intraventricular nerve growth factor and brain-derived neurotrophic factor administration | Q42496429 | ||
High-affinity nerve growth factor receptor (Trk) immunoreactivity is localized in cholinergic neurons of the basal forebrain and striatum in the adult rat brain | Q42505736 | ||
Striatal dopamine output is compromised within +/− BDNF mice | Q42514742 | ||
Neurotrophins stimulate the release of dopamine from rat mesencephalic neurons via Trk and p75Lntr receptors | Q42519834 | ||
Survival of cholinergic forebrain neurons in developing p75NGFR-deficient mice | Q42527534 | ||
Functional properties of AMPA and NMDA receptors expressed in identified types of basal ganglia neurons. | Q42528666 | ||
Nerve growth factor effects on cholinergic neurons of neostriatum and nucleus accumbens in the adult rat. | Q43482932 | ||
The uniqueness of being a neurotrophin receptor | Q43635038 | ||
P921 | main subject | Huntington's disease | Q190564 |
P304 | page(s) | 195-229 | |
P577 | publication date | 2004-01-01 | |
P13046 | publication type of scholarly work | review article | Q7318358 |
P1433 | published in | Progress in Brain Research | Q15800382 |
P1476 | title | Neurotrophic factors in Huntington's disease | |
P478 | volume | 146 |
Q33946881 | Brain-derived neurotrophic factor and the development of structural neuronal connectivity |
Q40519742 | Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease. |
Q90140618 | Cell-Autonomous and Non-cell-Autonomous Pathogenic Mechanisms in Huntington's Disease: Insights from In Vitro and In Vivo Models |
Q33559739 | Ciliary neurotrophic factor protects striatal neurons against excitotoxicity by enhancing glial glutamate uptake |
Q35487248 | Conditional BDNF release under pathological conditions improves Huntington's disease pathology by delaying neuronal dysfunction |
Q39937019 | Design of a conformationally defined and proteolytically stable circular mimetic of brain-derived neurotrophic factor. |
Q37825629 | Experimental Surgical Therapies for Huntington's Disease |
Q34212651 | FGF-2 promotes neurogenesis and neuroprotection and prolongs survival in a transgenic mouse model of Huntington's disease |
Q37176918 | GDNF control of the glutamatergic cortico-striatal pathway requires tonic activation of adenosine A receptors |
Q59796297 | GM604 regulates developmental neurogenesis pathways and the expression of genes associated with amyotrophic lateral sclerosis |
Q35675598 | Genetically engineered mesenchymal stem cells as a proposed therapeutic for Huntington's disease |
Q30489737 | Glial cell line-derived neurotrophic factor and antioxidants preserve the electrical responsiveness of the spiral ganglion neurons after experimentally induced deafness |
Q92155440 | Health Benefits of Endurance Training: Implications of the Brain-Derived Neurotrophic Factor-A Systematic Review |
Q36939755 | Human Mesenchymal Stem Cells Genetically Engineered to Overexpress Brain-derived Neurotrophic Factor Improve Outcomes in Huntington's Disease Mouse Models. |
Q35158643 | Huntington's Disease: From Mutant Huntingtin Protein to Neurotrophic Factor Therapy |
Q36809523 | Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies. |
Q44384196 | Injectable hydrogels providing sustained delivery of vascular endothelial growth factor are neuroprotective in a rat model of Huntington's disease |
Q36281838 | Interactions of interleukin-1 with neurotrophic factors in the central nervous system: beneficial or detrimental? |
Q88918162 | Lasting changes induced by mild alcohol exposure during embryonic development in BDNF, NCAM and synaptophysin-positive neurons quantified in adult zebrafish |
Q34473474 | Mesenchymal stem cells for the treatment of neurodegenerative disease. |
Q42030016 | Mesenchymal stem cells for trinucleotide repeat disorders |
Q64923893 | Neuroprotection: Pro-survival and Anti-neurotoxic Mechanisms as Therapeutic Strategies in Neurodegeneration. |
Q37322226 | Neurotrophic factors in neurodegenerative disorders : potential for therapy |
Q38096248 | Oligodendroglia and neurotrophic factors in neurodegeneration |
Q36142706 | Potential Drugs and Methods for Preventing or Delaying the Progression of Huntington's Disease |
Q39041214 | Targeting the Cholinergic System to Develop a Novel Therapy for Huntington's Disease |
Q36684263 | The corticostriatal pathway in Huntington's disease |
Q36358871 | The use of the R6 transgenic mouse models of Huntington's disease in attempts to develop novel therapeutic strategies |