Fetal striatal allografts reverse cognitive deficits in a primate model of Huntington disease

scientific article published in August 1998

Fetal striatal allografts reverse cognitive deficits in a primate model of Huntington disease is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1010021729
P356DOI10.1038/NM0898-963
P698PubMed publication ID9701252

P50authorEmmanuel BrouilletQ42839922
P2093author name stringCondé F
Hantraye P
Palfi S
Peschanski M
Riche D
Chibois A
Dautry C
Mittoux V
P2860cites workChronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primatesQ34103541
Graft-induced behavioral recovery in an animal model of Huntington diseaseQ35601129
Intrastriatal transplantation of cross-species fetal striatal cells reduces abnormal movements in a primate model of Huntington diseaseQ37600345
Comparison of the Neuropsychological Deficits Associated With Early and Advanced Huntington's DiseaseQ39859862
Rationale for intrastriatal grafting of striatal neuroblasts in patients with Huntington's diseaseQ40369954
A primate model of Huntington's disease: behavioral and anatomical studies of unilateral excitotoxic lesions of the caudate-putamen in the baboonQ41197259
Selective putaminal excitotoxic lesions in non-human primates model the movement disorder of Huntington disease.Q42279258
Monitoring of cell viability in suspensions of embryonic CNS tissue and its use as a criterion for intracerebral graft survivalQ42435290
Increased proportion of acetylcholinesterase-rich zones and improved morphological integration in host striatum of fetal grafts derived from the lateral but not the medial ganglionic eminence.Q42491088
Ontogeny of human striatal DARPP-32 neurons in fetuses and following xenografting to the adult rat brainQ45291607
Chronic 3-nitropropionic acid treatment in baboons replicates the cognitive and motor deficits of Huntington's diseaseQ45291813
Differential cognitive impairment in Alzheimer's disease and Huntington's diseaseQ45299007
Successful performance by monkeys with lesions of the hippocampal formation on AB and object retrieval, two tasks that mark developmental changes in human infantsQ46302522
Striatal graft-associated recovery of a lesion-induced performance deficit in the rat requires learning to use the transplantQ48551710
Enduring Cognitive Deficits and Cortical Dopamine Dysfunction in Monkeys After Long-Term Administration of PhencyclidineQ48637204
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleusQ48691482
A stereotaxic atlas of the brain of the cynomolgus monkey (Macaca fascicularis)Q70325126
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectHuntington's diseaseQ190564
striatumQ1319792
P304page(s)963-966
P577publication date1998-08-01
P1433published inNature medicineQ1633234
P1476titleFetal striatal allografts reverse cognitive deficits in a primate model of Huntington disease
P478volume4

Reverse relations

cites work (P2860)
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Q45305166Expression of mutated huntingtin fragment in the putamen is sufficient to produce abnormal movement in non-human primates
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