| scholarly article | Q13442814 |
| P50 | author | Hironori Katoh | Q73020021 |
| Satoshi Fujimoto | Q82408524 | ||
| Shuhei Ueda | Q84637231 | ||
| P2093 | author name string | Manabu Negishi | |
| Shingo Takeuchi | |||
| Kohei Harada | |||
| Nao Hiramoto-Yamaki | |||
| P2860 | cites work | EphA2 overexpression causes tumorigenesis of mammary epithelial cells. | Q43561178 |
| c-Cbl-dependent EphA2 protein degradation is induced by ligand binding. | Q44259057 | ||
| EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin | Q45345123 | ||
| Vav family GEFs link activated Ephs to endocytosis and axon guidance | Q46453264 | ||
| Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates. | Q51807012 | ||
| Cortactin Overexpression Regulates Actin-Related Protein 2/3 Complex Activity, Motility, and Invasion in Carcinomas with Chromosome 11q13 Amplification | Q57374739 | ||
| Efficient gene transfer into the embryonic mouse brain using in vivo electroporation | Q77469506 | ||
| Regulation of EphA2 receptor endocytosis by SHIP2 lipid phosphatase via phosphatidylinositol 3-Kinase-dependent Rac1 activation | Q79393705 | ||
| Activation of Rac1 by a Crk SH3-binding protein, DOCK180 | Q22007972 | ||
| WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac | Q22008483 | ||
| Non-adherent cell-specific expression of DOCK2, a member of the human CDM-family proteins | Q22010788 | ||
| CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration | Q24291780 | ||
| Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex | Q24301883 | ||
| EphA4-mediated Rho activation via Vsm-RhoGEF expressed specifically in vascular smooth muscle cells | Q24303555 | ||
| EphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with Akt | Q24310260 | ||
| RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo | Q24310774 | ||
| DOCK10-mediated Cdc42 activation is necessary for amoeboid invasion of melanoma cells | Q24319212 | ||
| TIM, a Dbl-related protein, regulates cell shape and cytoskeletal organization in a Rho-dependent manner | Q24322063 | ||
| Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers. | Q24537280 | ||
| A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling | Q24539212 | ||
| SGEF, a RhoG guanine nucleotide exchange factor that stimulates macropinocytosis | Q24561585 | ||
| ELMO1 and Dock180, a bipartite Rac1 guanine nucleotide exchange factor, promote human glioma cell invasion | Q24623558 | ||
| GEF what? Dock180 and related proteins help Rac to polarize cells in new ways | Q24633334 | ||
| ErbB2 directly activates the exchange factor Dock7 to promote Schwann cell migration | Q24648256 | ||
| Function of the N-terminus of zizimin1: autoinhibition and membrane targeting. | Q24657963 | ||
| Cellular motility driven by assembly and disassembly of actin filaments | Q27860676 | ||
| Rho GTPases in cell biology | Q27860969 | ||
| Eph-dependent tyrosine phosphorylation of ephexin1 modulates growth cone collapse | Q28115583 | ||
| TrioGEF1 controls Rac- and Cdc42-dependent cell structures through the direct activation of rhoG | Q28143625 | ||
| DOCK4, a GTPase activator, is disrupted during tumorigenesis | Q28182054 | ||
| Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity | Q28214812 | ||
| Rac1 and RhoG promote cell survival by the activation of PI3K and Akt, independently of their ability to stimulate JNK and NF-kappaB | Q28216113 | ||
| Dock4 is regulated by RhoG and promotes Rac-dependent cell migration | Q28267493 | ||
| CZH proteins: a new family of Rho-GEFs | Q28279327 | ||
| Activation of Rac1 by RhoG regulates cell migration | Q28285908 | ||
| Dock4 regulates dendritic development in hippocampal neurons | Q28286691 | ||
| Molecular association between beta-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/beta-catenin signaling | Q28287909 | ||
| Rac activation and inactivation control plasticity of tumor cell movement | Q28299776 | ||
| RhoG regulates anoikis through a phosphatidylinositol 3-kinase-dependent mechanism | Q28306381 | ||
| N-WASP and cortactin are involved in invadopodium-dependent chemotaxis to EGF in breast tumor cells | Q28571875 | ||
| Cdk5 regulates EphA4-mediated dendritic spine retraction through an ephexin1-dependent mechanism | Q28582482 | ||
| Rac-GAP alpha-chimerin regulates motor-circuit formation as a key mediator of EphrinB3/EphA4 forward signaling | Q28585059 | ||
| Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis | Q28586276 | ||
| Translocation of cortactin to the cell periphery is mediated by the small GTPase Rac1 | Q28678928 | ||
| RHO-GTPases and cancer | Q29616099 | ||
| Eph-ephrin bidirectional signaling in physiology and disease | Q29617975 | ||
| Characterization of rac and cdc42 activation in chemoattractant-stimulated human neutrophils using a novel assay for active GTPases | Q29618793 | ||
| ERBB receptors and cancer: the complexity of targeted inhibitors | Q29619520 | ||
| Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton | Q29620156 | ||
| WGEF is a novel RhoGEF expressed in intestine, liver, heart, and kidney. | Q30160832 | ||
| Cell migration is regulated by platelet-derived growth factor receptor endocytosis | Q30437225 | ||
| Suppression of RhoG activity is mediated by a syndecan 4-synectin-RhoGDI1 complex and is reversed by PKCalpha in a Rac1 activation pathway. | Q30437384 | ||
| The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling | Q30480823 | ||
| Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins | Q34143927 | ||
| MOCA induces membrane spreading by activating Rac1. | Q34289337 | ||
| Dock6, a Dock-C subfamily guanine nucleotide exchanger, has the dual specificity for Rac1 and Cdc42 and regulates neurite outgrowth | Q34596325 | ||
| Eph-ephrin signalling in adult tissues and cancer | Q37114287 | ||
| Cortactin in tumor invasiveness | Q37135990 | ||
| Rho GTPases in cancer cell biology | Q37156024 | ||
| RhoG promotes neural progenitor cell proliferation in mouse cerebral cortex. | Q37448289 | ||
| Cellular signaling of Dock family proteins in neural function | Q37606708 | ||
| Beta2-chimaerin binds to EphA receptors and regulates cell migration. | Q38355648 | ||
| Regulation of dendrite growth by the Cdc42 activator Zizimin1/Dock9 in hippocampal neurons | Q39892925 | ||
| Activation of the EGFR gene target EphA2 inhibits epidermal growth factor-induced cancer cell motility | Q40156318 | ||
| A conditional feedback loop regulates Ras activity through EphA2. | Q40385854 | ||
| Rac-WAVE2 signaling is involved in the invasive and metastatic phenotypes of murine melanoma cells. | Q40479116 | ||
| The small GTPases Cdc42Hs, Rac1 and RhoG delineate Raf-independent pathways that cooperate to transform NIH3T3 cells | Q42796070 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell biology | Q7141 |
| cell migration | Q189092 | ||
| cell chemotaxis | Q14901854 | ||
| Rho guanine nucleotide exchange factor 16 | Q21101965 | ||
| Dedicator of cytokinesis 4 | Q21114265 | ||
| EPH receptor A2 | Q21114359 | ||
| Ras homolog family member G | Q21114381 | ||
| Engulfment and cell motility 2 | Q21114397 | ||
| P1104 | number of pages | 17 | |
| P304 | page(s) | 461-477 | |
| P577 | publication date | 2010-08-02 | |
| P1433 | published in | Journal of Cell Biology | Q1524550 |
| P1476 | title | Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism | |
| P478 | volume | 190 |
| Q38716292 | A RhoG-mediated signaling pathway that modulates invadopodia dynamics in breast cancer cells. |
| Q28728612 | A method to find longevity-selected positions in the mammalian proteome |
| Q106518998 | CDC42 GEFs activate CDC42 |
| Q38531842 | Cell segregation in the vertebrate hindbrain: a matter of boundaries. |
| Q57031027 | Circular RNA and mRNA profiling reveal competing endogenous RNA networks during avian leukosis virus, subgroup J-induced tumorigenesis in chickens |
| Q35172911 | ClipR-59 interacts with Elmo2 and modulates myoblast fusion |
| Q28115187 | Crucial roles of RSK in cell motility by catalysing serine phosphorylation of EphA2 |
| Q87314310 | DOCK4 deletion at 7q31.1 in a de novo acute myeloid leukemia with a normal karyotype |
| Q51444087 | Design of novel lead molecules against RhoG protein as cancer target - a computational study. |
| Q37580974 | Dock protein family in brain development and neurological disease |
| Q38713729 | ELMO proteins transduce G protein-coupled receptor signal to control reorganization of actin cytoskeleton in chemotaxis of eukaryotic cells |
| Q64246002 | Emerging Roles of Ephexins in Physiology and Disease |
| Q42321188 | Emerging role of ILK and ELMO2 in the integration of adhesion and migration pathways |
| Q36125059 | Eph receptor and ephrin function in breast, gut, and skin epithelia |
| Q37122330 | Eph receptor signaling and ephrins |
| Q38209232 | Eph- and ephrin-dependent mechanisms in tumor and stem cell dynamics |
| Q37971902 | Eph-dependent cell-cell adhesion and segregation in development and cancer. |
| Q36045304 | Eph/ephrin signaling in epidermal differentiation and disease |
| Q26864082 | EphA receptor signaling--complexity and emerging themes |
| Q30539320 | EphA2 cleavage by MT1-MMP triggers single cancer cell invasion via homotypic cell repulsion |
| Q37385339 | EphA2 signaling following endocytosis: role of Tiam1. |
| Q52611754 | Ephexin4 and EphA2 mediate resistance to anoikis through RhoG and phosphatidylinositol 3-kinase. |
| Q41263892 | Ephexin4-mediated promotion of cell migration and anoikis resistance is regulated by serine 897 phosphorylation of EphA2. |
| Q34845606 | EphrinA2 regulates clathrin mediated KSHV endocytosis in fibroblast cells by coordinating integrin-associated signaling and c-Cbl directed polyubiquitination |
| Q35712209 | Epidermal growth factor induction of front-rear polarity and migration in keratinocytes is mediated by integrin-linked kinase and ELMO2. |
| Q98564728 | FYN is required for ARHGEF16 to promote proliferation and migration in colon cancer cells |
| Q38331490 | Function and interactions of the Ysc84/SH3yl1 family of actin- and lipid-binding proteins. |
| Q57280907 | GLI2 promotes cell proliferation and migration through transcriptional activation of ARHGEF16 in human glioma cells |
| Q34263351 | Human cataract mutations in EPHA2 SAM domain alter receptor stability and function |
| Q61307076 | Identification and validation of DOCK4 as a potential biomarker for risk of bone metastasis development in patients with early breast cancer |
| Q40365068 | Immunohistochemical demonstration of EphA2 processing by MT1-MMP in invasive cutaneous squamous cell carcinoma |
| Q33860875 | Intermolecular steric inhibition of Ephexin4 is relieved by Elmo1. |
| Q35983048 | Kaposi's sarcoma-associated herpesvirus interacts with EphrinA2 receptor to amplify signaling essential for productive infection |
| Q98200156 | Kinase activity-independent role of EphA2 in the regulation of M-phase progression |
| Q91899883 | Loss of Function of DOCK4 in Myelodysplastic Syndromes Stem Cells is Restored by Inhibitors of DOCK4 Signaling Networks |
| Q37153028 | Loss-of-Function Mutations in ELMO2 Cause Intraosseous Vascular Malformation by Impeding RAC1 Signaling |
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| Q35974524 | Multivariate models from RNA-Seq SNVs yield candidate molecular targets for biomarker discovery: SNV-DA |
| Q33853031 | Navigating breast cancer: axon guidance molecules as breast cancer tumor suppressors and oncogenes. |
| Q38257674 | Phosphotyrosine profiling of NSCLC cells in response to EGF and HGF reveals network specific mediators of invasion. |
| Q38369833 | Platelet Rho GTPases-a focus on novel players, roles and relationships. |
| Q28116202 | Protein kinase A can block EphA2 receptor-mediated cell repulsion by increasing EphA2 S897 phosphorylation |
| Q36380708 | Proteolysis of EphA2 Converts It from a Tumor Suppressor to an Oncoprotein |
| Q36245528 | Proteomic analysis of acquired tamoxifen resistance in MCF-7 cells reveals expression signatures associated with enhanced migration |
| Q39347021 | R-Ras controls axon branching through afadin in cortical neurons |
| Q106518954 | RAC1 GEFs activate RAC1 |
| Q64245597 | RHOG Activates RAC1 through CDC42 Leading to Tube Formation in Vascular Endothelial Cells |
| Q106518986 | RHOG GEFs activate RHOG |
| Q106518989 | RHOG binds effectors at the plasma membrane |
| Q36849290 | Rac GEF Dock4 interacts with cortactin to regulate dendritic spine formation |
| Q35854151 | Rac signaling in breast cancer: a tale of GEFs and GAPs. |
| Q41001481 | Regulation of circular dorsal ruffles, macropinocytosis, and cell migration by RhoG and its exchange factor, Trio |
| Q45354950 | Role of the EphB2 receptor in autophagy, apoptosis and invasion in human breast cancer cells |
| Q41543057 | SOCS2 Binds to and Regulates EphA2 through Multiple Mechanisms. |
| Q36331953 | Screening for tumor suppressors: Loss of ephrin receptor A2 cooperates with oncogenic KRas in promoting lung adenocarcinoma |
| Q57821602 | Silencing ELMO3 Inhibits the Growth, Invasion, and Metastasis of Gastric Cancer |
| Q88223140 | Spatial control of membrane receptor function using ligand nanocalipers |
| Q38006838 | The Eph/Ephrin family in cancer metastasis: communication at the service of invasion |
| Q59800632 | The Intermolecular Interaction of Ephexin4 Leads to Autoinhibition by Impeding Binding of RhoG |
| Q30009843 | The atypical guanine nucleotide exchange factor Dock4 regulates neurite differentiation through modulation of Rac1 GTPase and actin dynamics |
| Q51741088 | The intracellular juxtamembrane domain of discoidin domain receptor 2 (DDR2) is essential for receptor activation and DDR2-mediated cancer progression. |
| Q30010159 | The invasive capacity of HPV transformed cells requires the hDlg-dependent enhancement of SGEF/RhoG activity |
| Q36402719 | The multifaceted roles of Eph/ephrin signaling in breast cancer |
| Q38150596 | The role of EPH receptors in cancer-related epithelial-mesenchymal transition |
| Q37960345 | The role of endocytosis in activating and regulating signal transduction |
| Q64121484 | The small GTPase RhoG regulates microtubule-mediated focal adhesion disassembly |
| Q36082708 | Tyrosine Phosphorylation of SGEF Regulates RhoG Activity and Cell Migration. |
| Q91656931 | YAP Partially Reprograms Chromatin Accessibility to Directly Induce Adult Cardiogenesis In Vivo |
| Q39347979 | miR-124-regulated RhoG reduces neuronal process complexity via ELMO/Dock180/Rac1 and Cdc42 signalling |
| Q39213258 | miR-124-regulated RhoG: A conductor of neuronal process complexity |
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