| scholarly article | Q13442814 |
| P50 | author | Guanglei Zhuang | Q43182764 |
| Jin Chen | Q55189464 | ||
| P2093 | author name string | Christopher W Cowan | |
| Wojciech Swat | |||
| Dana Brantley-Sieders | |||
| Sonja G Hunter | |||
| P2860 | cites work | Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins | Q22010673 |
| EphA4-mediated Rho activation via Vsm-RhoGEF expressed specifically in vascular smooth muscle cells | Q24303555 | ||
| ELK and LERK-2 in developing kidney and microvascular endothelial assembly | Q36835207 | ||
| EphB4 controls blood vascular morphogenesis during postnatal angiogenesis | Q40327178 | ||
| Impaired tumor microenvironment in EphA2-deficient mice inhibits tumor angiogenesis and metastatic progression | Q40372965 | ||
| EphrinA1-induced cytoskeletal re-organization requires FAK and p130(cas). | Q40716314 | ||
| Distinct role of phosphatidylinositol 3-kinase and Rho family GTPases in Vav3-induced cell transformation, cell motility, and morphological changes | Q42817866 | ||
| Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo. | Q44172489 | ||
| Antiangiogenic and antitumor efficacy of EphA2 receptor antagonist | Q44761792 | ||
| EphA2 receptor tyrosine kinase regulates endothelial cell migration and vascular assembly through phosphoinositide 3-kinase-mediated Rac1 GTPase activation. | Q44822101 | ||
| Vav family GEFs link activated Ephs to endocytosis and axon guidance | Q46453264 | ||
| A kinase-dependent role for EphA2 receptor in promoting tumor growth and metastasis. | Q46653193 | ||
| The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization | Q46699319 | ||
| Signal transduction through Vav-2 participates in humoral immune responses and B cell maturation | Q58419187 | ||
| Compensation between Vav-1 and Vav-2 in B cell development and antigen receptor signaling | Q73934023 | ||
| Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vav1 | Q77649221 | ||
| Molecular Distinction and Angiogenic Interaction between Embryonic Arteries and Veins Revealed by ephrin-B2 and Its Receptor Eph-B4 | Q24336334 | ||
| Vav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation | Q24515205 | ||
| Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2 | Q24533404 | ||
| Vav family proteins couple to diverse cell surface receptors | Q24552004 | ||
| Regulatory and signaling properties of the Vav family | Q24554307 | ||
| Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis | Q24608892 | ||
| Rho GTPases and the Actin Cytoskeleton | Q27860579 | ||
| Replacing two conserved tyrosines of the EphB2 receptor with glutamic acid prevents binding of SH2 domains without abrogating kinase activity and biological responses | Q28143168 | ||
| Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development | Q28145776 | ||
| Mechanisms and functions of Eph and ephrin signalling | Q28208291 | ||
| Activation of the Eck receptor protein tyrosine kinase stimulates phosphatidylinositol 3-kinase activity | Q28242069 | ||
| Complex formation between EphB2 and Src requires phosphorylation of tyrosine 611 in the EphB2 juxtamembrane region | Q28274112 | ||
| Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis | Q28286738 | ||
| Role of B61, the ligand for the Eck receptor tyrosine kinase, in TNF-alpha-induced angiogenesis | Q28287785 | ||
| Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells | Q28567890 | ||
| EphrinA1 inactivates integrin-mediated vascular smooth muscle cell spreading via the Rac/PAK pathway | Q28579324 | ||
| Vav2 is an activator of Cdc42, Rac1, and RhoA | Q28610652 | ||
| Role of Substrates and Products of PI 3-kinase in Regulating Activation of Rac-Related Guanosine Triphosphatases by Vav | Q28646540 | ||
| Phosphorylation of tyrosine residues in the kinase domain and juxtamembrane region regulates the biological and catalytic activities of Eph receptors | Q28647596 | ||
| Vascular-specific growth factors and blood vessel formation | Q29614780 | ||
| Rho GTPases and cell migration | Q29616714 | ||
| Tumorigenesis and the angiogenic switch | Q29619849 | ||
| Eph receptor signalling casts a wide net on cell behaviour | Q29619988 | ||
| Major transcript variants of VAV3, a new member of the VAV family of guanine nucleotide exchange factors | Q30175227 | ||
| Control of intramolecular interactions between the pleckstrin homology and Dbl homology domains of Vav and Sos1 regulates Rac binding. | Q33896745 | ||
| Vav1 regulates phospholipase cgamma activation and calcium responses in mast cells. | Q33968323 | ||
| VAV proteins as signal integrators for multi-subunit immune-recognition receptors | Q34718119 | ||
| Inhibition of VEGF-dependent multistage carcinogenesis by soluble EphA receptors | Q34773410 | ||
| Elevated matrix metalloprotease and angiostatin levels in integrin alpha 1 knockout mice cause reduced tumor vascularization | Q35051209 | ||
| Vav proteins, masters of the world of cytoskeleton organization. | Q35579688 | ||
| Eph receptor-ephrin bidirectional signals that target Ras and Rho proteins | Q35749432 | ||
| Eph receptor tyrosine kinases in angiogenesis: from development to disease. | Q35859771 | ||
| Eph receptor tyrosine kinases in tumor and tumor microenvironment | Q35950319 | ||
| Vav1/2/3-null Mice Define an Essential Role for Vav Family Proteins in Lymphocyte Development and Activation but a Differential Requirement in MAPK Signaling in T and B Cells | Q36371509 | ||
| P433 | issue | 13 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | angiogenesis | Q539568 |
| Ephrin A1 | Q21495546 | ||
| Eph receptor A2 | Q21979768 | ||
| Vav 2 oncogene | Q21989694 | ||
| Vav 3 oncogene | Q21989701 | ||
| guanine | Q169313 | ||
| P304 | page(s) | 4830-4842 | |
| P577 | publication date | 2006-07-01 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis | |
| P478 | volume | 26 |
| Q88413787 | (Iso-)form Matters: Differential Implication of Vav3 Variants in Ovarian Cancer |
| Q36557442 | Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans |
| Q36770031 | Analysis of the VAV3 as candidate gene for schizophrenia: evidences from voxel-based morphometry and mutation screening |
| Q28573443 | Astrocyte-produced ephrins inhibit schwann cell migration via VAV2 signaling |
| Q37746510 | Axon guidance molecules in vascular patterning |
| Q36682364 | Bidirectional ephrin/Eph signaling in synaptic functions |
| Q99210522 | Biochemical and NMR characterization of the interactions of Vav2-SH2 domain with lipids and the EphA2 juxtamembrane region on membrane |
| Q30498003 | Cooperative signaling between Slit2 and Ephrin-A1 regulates a balance between angiogenesis and angiostasis. |
| Q36844220 | Deciphering the signaling events that promote melanoma tumor cell vasculogenic mimicry and their link to embryonic vasculogenesis: role of the Eph receptors |
| Q30646148 | Elevated Slit2 Activity Impairs VEGF-Induced Angiogenesis and Tumor Neovascularization in EphA2-Deficient Endothelium |
| Q34469271 | Emerging strategies for EphA2 receptor targeting for cancer therapeutics |
| Q82863771 | Endogenous Ligand-Induced Activation of TLR4 in Pre-metastatic Phase Is Both Downstream and Upstream of TNF Signaling |
| Q36877332 | Endothelial EphA receptor stimulation increases lung vascular permeability |
| Q37122330 | Eph receptor signaling and ephrins |
| Q34021365 | Eph receptors and ephrins in cancer: bidirectional signalling and beyond |
| Q37131357 | Eph receptors in breast cancer: roles in tumor promotion and tumor suppression. |
| Q38209232 | Eph- and ephrin-dependent mechanisms in tumor and stem cell dynamics |
| Q35684746 | Eph-A2 promotes permeability and inflammatory responses to bleomycin-induced lung injury. |
| Q37971902 | Eph-dependent cell-cell adhesion and segregation in development and cancer. |
| Q37385339 | EphA2 signaling following endocytosis: role of Tiam1. |
| Q38725781 | EphB3 Stimulates Cell Migration and Metastasis in a Kinase-dependent Manner through Vav2-Rho GTPase Axis in Papillary Thyroid Cancer. |
| Q24294233 | Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism |
| Q80625748 | Ephrin-A1 stimulates migration of CD8+CCR7+ T lymphocytes |
| Q40142816 | EphrinA1 activates a Src/focal adhesion kinase-mediated motility response leading to rho-dependent actino/myosin contractility |
| Q35245788 | Essential role for vav Guanine nucleotide exchange factors in brain-derived neurotrophic factor-induced dendritic spine growth and synapse plasticity |
| Q57141071 | Evaluation of Vav3.1 as prognostic marker in endometrial cancer |
| Q36210720 | Function of the nucleotide exchange activity of vav1 in T cell development and activation |
| Q50696862 | HOXA13 directly regulates EphA6 and EphA7 expression in the genital tubercle vascular endothelia |
| Q37337431 | Host deficiency in Vav2/3 guanine nucleotide exchange factors impairs tumor growth, survival, and angiogenesis in vivo |
| Q49823898 | Hypoxia-Preconditioned Human Umbilical Vein Endothelial Cells Protect Against Neurovascular Damage After Hypoxic Ischemia in Neonatal Brain. |
| Q36701792 | Identification and functional analysis of phosphorylated tyrosine residues within EphA2 receptor tyrosine kinase. |
| Q38856373 | Identification of a Vav2-dependent mechanism for GDNF/Ret control of mesolimbic DAT trafficking |
| Q24294195 | Identification of phosphotyrosine binding domain-containing proteins as novel downstream targets of the EphA8 signaling function |
| Q43074170 | Major signaling pathways in migrating neuroblasts |
| Q40822068 | MiR-93 Targeting EphA4 Promotes Neurite Outgrowth from Spinal Cord Neurons |
| Q91899850 | Next-generation RNA sequencing of FFPE subsections reveals highly conserved stromal reprogramming between canine and human mammary carcinoma |
| Q33746458 | Novel aspects of the roles of Rac1 GTPase in the cardiovascular system |
| Q36926620 | Paxillin kinase linker (PKL) regulates Vav2 signaling during cell spreading and migration |
| Q38943113 | Phosphotyrosine profiling identifies ephrin receptor A2 as a potential therapeutic target in esophageal squamous-cell carcinoma. |
| Q35165191 | Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways. |
| Q28585639 | Regulation of mammary gland branching morphogenesis by EphA2 receptor tyrosine kinase |
| Q36765650 | Regulation of tumor initiation and metastatic progression by Eph receptor tyrosine kinases. |
| Q26992281 | Rho GAPs and GEFs: controling switches in endothelial cell adhesion |
| Q38069347 | Rho guanine exchange factors in blood vessels: fine-tuners of angiogenesis and vascular function |
| Q92637800 | Roles of EphA2 Receptor in Angiogenesis Signaling Pathway of Glioblastoma Multiforme |
| Q88985818 | Safety, pharmacokinetics, and preliminary efficacy of E6201 in patients with advanced solid tumours, including melanoma: results of a phase 1 study |
| Q41875227 | Small molecules can selectively inhibit ephrin binding to the EphA4 and EphA2 receptors |
| Q39784785 | Sos1 disruption impairs cellular proliferation and viability through an increase in mitochondrial oxidative stress in primary MEFs. |
| Q42852897 | Specificity of HCPTP variants toward EphA2 tyrosines by quantitative selected reaction monitoring. |
| Q28116370 | Structural basis for a novel interaction between TXNIP and Vav2 |
| Q37315118 | Targeted overexpression of vav3 oncogene in prostatic epithelium induces nonbacterial prostatitis and prostate cancer |
| Q38006838 | The Eph/Ephrin family in cancer metastasis: communication at the service of invasion |
| Q36950556 | The EphA2 receptor and ephrinA1 ligand in solid tumors: function and therapeutic targeting |
| Q27317069 | The Rho exchange factors Vav2 and Vav3 favor skin tumor initiation and promotion by engaging extracellular signaling loops |
| Q64882545 | The Vav GEF Family: An Evolutionary and Functional Perspective. |
| Q42089356 | The expression and prognostic value of the guanine nucleotide exchange factors (GEFs) Trio, Vav1 and TIAM-1 in human breast cancer |
| Q41697096 | The guanine nucleotide exchange factor Vav3 regulates differentiation of progenitor cells in the developing mouse retina |
| Q37960345 | The role of endocytosis in activating and regulating signal transduction |
| Q38174793 | Therapeutic targeting of EPH receptors and their ligands |
| Q39005860 | Tobacco smoke induces epithelial barrier dysfunction via receptor EphA2 signaling |
| Q57372562 | Transcriptional Signature of Epidermal Keratinocytes Subjected toin VitroScratch Wounding Reveals Selective Roles for ERK1/2, p38, and Phosphatidylinositol 3-Kinase Signaling Pathways |
| Q53374546 | Vav GEFs regulate macrophage morphology and adhesion-induced Rac and Rho activation |
| Q122950761 | Vav Proteins in Development of the Brain: A Potential Relationship to the Pathogenesis of Congenital Zika Syndrome? |
| Q27026905 | Vav family exchange factors: an integrated regulatory and functional view |
| Q26782144 | Vav1: A Dr. Jekyll and Mr. Hyde protein--good for the hematopoietic system, bad for cancer |
| Q133054893 | Vav2 is a novel APP-interacting protein that regulates APP protein level |
| Q96302801 | Vav2 pharmaco-mimetic mice reveal the therapeutic value and caveats of the catalytic inactivation of a Rho exchange factor |
| Q34361011 | Vav3 is involved in GABAergic axon guidance events important for the proper function of brainstem neurons controlling cardiovascular, respiratory, and renal parameters. |
| Q30384535 | Vav3 oncogene is upregulated and a poor prognostic factor in breast cancer patients |
| Q39338100 | Vav3-Rac1 Signaling Regulates Prostate Cancer Metastasis with Elevated Vav3 Expression Correlating with Prostate Cancer Progression and Posttreatment Recurrence |
| Q30493610 | Vav3-deficient mice exhibit a transient delay in cerebellar development |
| Q57987013 | Vav3-induced cytoskeletal dynamics contribute to heterotypic properties of endothelial barriers |
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