The protein-tyrosine kinase Syk interacts with the C-terminal region of tensin2

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The protein-tyrosine kinase Syk interacts with the C-terminal region of tensin2 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.BBAMCR.2011.10.001
P8608Fatcat IDrelease_2pfqzgyt5zhina2g7eskmdjhw4
P3181OpenCitations bibliographic resource ID4833797
P932PMC publication ID3273629
P698PubMed publication ID22019427
P5875ResearchGate publication ID51741788

P2093author name stringKyung D Moon
Qing Zhou
Robert L Geahlen
Xiaoying Zhang
P2860cites workThe Syk tyrosine kinase suppresses malignant growth of human breast cancer cellsQ24290151
Interaction of deleted in liver cancer 1 with tensin2 in caveolae and implications in tumor suppressionQ24301470
axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinaseQ24310364
Molecular basis for a direct interaction between the Syk protein-tyrosine kinase and phosphoinositide 3-kinaseQ24313357
The protein-tyrosine kinase Syk interacts with TRAF-interacting protein TRIP in breast epithelial cellsQ24317705
Gas6/Axl signaling activates the phosphatidylinositol 3-kinase/Akt1 survival pathway to protect oligodendrocytes from tumor necrosis factor alpha-induced apoptosisQ24337862
The phosphotyrosine-independent interaction of DLC-1 and the SH2 domain of cten regulates focal adhesion localization and growth suppression activity of DLC-1Q24338316
Tensin1 and a previously undocumented family member, tensin2, positively regulate cell migrationQ24530395
RETRACTED: A promiscuous liaison between IL-15 receptor and Axl receptor tyrosine kinase in cell death controlQ24540107
Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signalingQ24553489
Structure of the PTB domain of tensin1 and a model for its recruitment to fibrillar adhesionsQ24648817
Oncogenic inhibition by a deleted in liver cancer gene requires cooperation between tensin binding and Rho-specific GTPase-activating protein activitiesQ24684712
Syk-mediated translocation of PI3Kdelta to the leading edge controls lamellipodium formation and migration of leukocytesQ27302372
Syk expression and novel function in a wide variety of tissuesQ28202066
Interaction of Axl receptor tyrosine kinase with C1-TEN, a novel C1 domain-containing protein with homology to tensinQ28216811
C1-TEN is a negative regulator of the Akt/PKB signal transduction pathway and inhibits cell survival, proliferation, and migrationQ28244101
Tensin2 variant 3 is associated with aggressive tumor behavior in human hepatocellular carcinomaQ28265813
Cbl-mediated negative regulation of the Syk tyrosine kinase. A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323Q28291812
Functional and physical interactions of Syk family kinases with the Vav proto-oncogene productQ28300755
Inhibition of beta 2 integrin receptor and Syk kinase signaling in monocytes by the Src family kinase FgrQ28507457
A cytoplasmic inhibitor of the JNK signal transduction pathwayQ28586970
Identification of the major sites of autophosphorylation of the murine protein-tyrosine kinase SykQ28619124
Syk, activated by cross-linking the B-cell antigen receptor, localizes to the cytosol where it interacts with and phosphorylates alpha-tubulin on tyrosineQ28626542
Tensin 2 modulates cell contractility in 3D collagen gels through the RhoGAP DLC1.Q30503860
Visualization of Syk-antigen receptor interactions using green fluorescent protein: differential roles for Syk and Lyn in the regulation of receptor capping and internalizationQ31838023
Proteomic and genetic approaches identify Syk as an AML targetQ33577098
In-depth analyses of kinase-dependent tyrosine phosphoproteomes based on metal ion-functionalized soluble nanopolymersQ33609440
An extensive survey of tyrosine phosphorylation revealing new sites in human mammary epithelial cellsQ34052779
The IL-15R alpha chain signals through association with Syk in human B cellsQ34102456
TensinQ34273615
Microtubule targeting of substrate contacts promotes their relaxation and dissociationQ36316658
The SYK tyrosine kinase: a crucial player in diverse biological functionsQ36662082
Syk and pTyr'd: Signaling through the B cell antigen receptorQ37237143
Role of the protein tyrosine kinase Syk in regulating cell-cell adhesion and motility in breast cancer cells.Q37459500
Tensin2 is a novel mediator in thrombopoietin (TPO)-induced cellular proliferation by promoting Akt signalingQ39551398
Tensin2 reduces intracellular phosphatidylinositol 3,4,5-trisphosphate levels at the plasma membraneQ39672653
Functional interaction between the ubiquitin-specific protease 25 and the SYK tyrosine kinaseQ39775628
Individual domains of Tensin2 exhibit distinct subcellular localisations and migratory effectsQ39800672
Deleted in liver cancer 1 (DLC1) utilizes a novel binding site for Tensin2 PTB domain interaction and is required for tumor-suppressive functionQ39851862
Gas6 anti-apoptotic signaling requires NF-kappa B activation.Q40796453
SYK is upstream of phosphoinositide 3-kinase in B cell receptor signalingQ40919280
Syk- and Lyn-dependent phosphorylation of Syk on multiple tyrosines following B cell activation includes a site that negatively regulates signalingQ40994288
Involvement of microtubules in the control of adhesion-dependent signal transduction.Q42808427
Inhibition of signaling through the B cell antigen receptor by the protooncogene product, c-Cbl, requires Syk tyrosine 317 and the c-Cbl phosphotyrosine-binding domainQ73201940
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
kinase bindingQ14864244
Tensin 2Q21110634
P1104number of pages7
P304page(s)199-205
P577publication date2012-02-01
P1433published inBiochimica et Biophysica ActaQ864239
P1476titleThe protein-tyrosine kinase Syk interacts with the C-terminal region of tensin2
P478volume1823

Reverse relations

cites work (P2860)
Q59136222AXL phosphorylates and up-regulates TNS2 and its implications in IRS-1-associated metabolism in cancer cells
Q37437434Down-regulation of tensin2 enhances tumorigenicity and is associated with a variety of cancers
Q38471666Downregulation of spleen tyrosine kinase in hepatocellular carcinoma by promoter CpG island hypermethylation and its potential role in carcinogenesis

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