| P50 | author | Robert L. Geahlen | Q42692859 |
| P2093 | author name string | Kyung D Moon | |
| | Qing Zhou | |
| | Marietta L Harrison | |
| | Pradip De | |
| | Donald L Durden | |
| | Carol B Post | |
| P2860 | cites work | Phospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk | Q24317490 |
| | Identification of the site in the Syk protein tyrosine kinase that binds the SH2 domain of Lck | Q24322561 |
| | Differential effect of the inhibition of Grb2-SH3 interactions in platelet activation induced by thrombin and by Fc receptor engagement | Q24534090 |
| | Human spleen tyrosine kinase p72Syk associates with the Src-family kinase p53/56Lyn and a 120-kDa phosphoprotein | Q24562809 |
| | Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase | Q27617539 |
| | Polymerization of the SAM domain of TEL in leukemogenesis and transcriptional repression | Q27633822 |
| | SH2 domains recognize specific phosphopeptide sequences | Q27860748 |
| | Beta-chemokine receptor CCR5 signals through SHP1, SHP2, and Syk | Q28140552 |
| | Tyrosine kinase SYK: essential functions for immunoreceptor signalling | Q28145413 |
| | Role of the docking protein Gab2 in beta(1)-integrin signaling pathway-mediated hematopoietic cell adhesion and migration | Q28207410 |
| | CrkL is an adapter for Wiskott-Aldrich syndrome protein and Syk | Q28213508 |
| | Coordinated regulation of the tyrosine phosphorylation of Cbl by Fyn and Syk tyrosine kinases | Q28267092 |
| | Phosphoinositide 3-kinase and p72syk noncovalently associate with the low affinity Fc gamma receptor on human platelets through an immunoreceptor tyrosine-based activation motif. Reconstitution with synthetic phosphopeptides | Q28278984 |
| | Cbl-mediated negative regulation of the Syk tyrosine kinase. A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323 | Q28291812 |
| | Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product | Q28300755 |
| | The non-receptor tyrosine kinase Syk is a target of Cbl-mediated ubiquitylation upon B-cell receptor stimulation. | Q28366332 |
| | Inhibition of beta 2 integrin receptor and Syk kinase signaling in monocytes by the Src family kinase Fgr | Q28507457 |
| | Phosphorylation of Tyr342 in the linker region of Syk is critical for Fc epsilon RI signaling in mast cells | Q28567689 |
| | Syk regulation of phosphoinositide 3-kinase-dependent NK cell function | Q28610674 |
| | Identification of the major sites of autophosphorylation of the murine protein-tyrosine kinase Syk | Q28619124 |
| | Syk, activated by cross-linking the B-cell antigen receptor, localizes to the cytosol where it interacts with and phosphorylates alpha-tubulin on tyrosine | Q28626542 |
| | A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages | Q28634082 |
| | Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt | Q28645569 |
| | BCAP | Q29304524 |
| | Catalytic specificity of protein-tyrosine kinases is critical for selective signalling | Q29616451 |
| | Constitutive kinase activation of the TEL-Syk fusion gene in myelodysplastic syndrome with t(9;12)(q22;p12). | Q31835118 |
| | The Cbl phosphotyrosine-binding domain selects a D(N/D)XpY motif and binds to the Tyr292 negative regulatory phosphorylation site of ZAP-70. | Q32170429 |
| | Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation | Q33890664 |
| | Proximal protein tyrosine kinases in immunoreceptor signaling | Q34282313 |
| | Cbl-b negatively regulates B cell antigen receptor signaling in mature B cells through ubiquitination of the tyrosine kinase Syk. | Q36370786 |
| | Interactions between SH2 domains and tyrosine-phosphorylated platelet-derived growth factor beta-receptor sequences: analysis of kinetic parameters by a novel biosensor-based approach | Q36686508 |
| | YMXM motifs of IRS-1 define substrate specificity of the insulin receptor kinase | Q36875986 |
| | TEL-Syk fusion constitutively activates PI3-K/Akt, MAPK and JAK2-independent STAT5 signal pathways | Q40594564 |
| | Regulation of Akt-dependent cell survival by Syk and Rac. | Q40695243 |
| | Activation of Syk tyrosine kinase is required for c-Cbl-mediated ubiquitination of Fcepsilon RI and Syk in RBL cells. | Q40714974 |
| | Regulation of signaling in B cells through the phosphorylation of Syk on linker region tyrosines. A mechanism for negative signaling by the Lyn tyrosine kinase | Q40723397 |
| | Signal transduction by human-restricted Fc gamma RIIa involves three distinct cytoplasmic kinase families leading to phagocytosis | Q40794220 |
| | Syk is required for the activation of Akt survival pathway in B cells exposed to oxidative stress | Q40867069 |
| | B cell antigen receptor-induced activation of Akt promotes B cell survival and is dependent on Syk kinase | Q40867426 |
| | SYK is upstream of phosphoinositide 3-kinase in B cell receptor signaling | Q40919280 |
| | The Gab1 protein is a docking site for multiple proteins involved in signaling by the B cell antigen receptor. | Q40996799 |
| | Treatment of T cells with 2-hydroxymyristic acid inhibits the myristoylation and alters the stability of p56lck | Q41528348 |
| | A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor | Q41879451 |
| | Translocation, activation and association of protein-tyrosine kinase (p72syk) with phosphatidylinositol 3-kinase are early events during platelet activation | Q42491814 |
| | PTEN controls immunoreceptor (immunoreceptor tyrosine-based activation motif) signaling and the activation of Rac. | Q43847751 |
| | Diversity in the SH2 domain family phosphotyrosyl peptide binding site | Q44408568 |
| | Phosphoinositide 3-Kinase and p72 Noncovalently Associate with the Low Affinity Fc Receptor on Human Platelets through an Immunoreceptor Tyrosine-based Activation Motif | Q56016569 |
| | Point mutation of a tyrosine in the linker region of Syk results in a gain of function | Q73289672 |
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1543-1551 | |
| P577 | publication date | 2004-11-09 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Molecular basis for a direct interaction between the Syk protein-tyrosine kinase and phosphoinositide 3-kinase | |
| P478 | volume | 280 | |