| scholarly article | Q13442814 |
| P2093 | author name string | T. Meyer | |
| K. G. Peters | |||
| L. Huang | |||
| C. D. Kontos | |||
| J. D. York | |||
| M. A. Blanar | |||
| T. P. Stauffer | |||
| W. P. Yang | |||
| P2860 | cites work | Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning | Q24310148 |
| Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor | Q24311075 | ||
| Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis | Q24313372 | ||
| Molecular cloning and characterization of a novel receptor protein tyrosine kinase from human placenta | Q24314368 | ||
| Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation | Q24316945 | ||
| Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2 | Q24319816 | ||
| A Grb2-associated docking protein in EGF- and insulin-receptor signalling | Q24321653 | ||
| Phosphorylation and activation of p70s6k by PDK1 | Q24323433 | ||
| Interaction of the Flt-1 tyrosine kinase receptor with the p85 subunit of phosphatidylinositol 3-kinase. Mapping of a novel site involved in binding | Q24336437 | ||
| Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor | Q24648537 | ||
| Compartmentalized IgE receptor-mediated signal transduction in living cells | Q24683610 | ||
| Crystal structure of the PI 3-kinase p85 amino-terminal SH2 domain and its phosphopeptide complexes | Q27732607 | ||
| Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery | Q27860586 | ||
| SH2 domains recognize specific phosphopeptide sequences | Q27860748 | ||
| INP51, a yeast inositol polyphosphate 5-phosphatase required for phosphatidylinositol 4,5-bisphosphate homeostasis and whose absence confers a cold-resistant phenotype | Q27933176 | ||
| Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B | Q28116107 | ||
| Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit | Q28211409 | ||
| Interleukin-3 induces the association of the inositol 5-phosphatase SHIP with SHP2 | Q28235496 | ||
| Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt | Q28255373 | ||
| Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins | Q28257012 | ||
| Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate | Q28280837 | ||
| GRB2 and SH-PTP2: potentially important endothelial signaling molecules downstream of the TEK/TIE2 receptor tyrosine kinase | Q28284046 | ||
| Phosphorylation of tyrosine 503 in the erythropoietin receptor (EpR) is essential for binding the P85 subunit of phosphatidylinositol (PI) 3-kinase and for EpR-associated PI 3-kinase activity | Q28289418 | ||
| Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis | Q28300359 | ||
| Direct association of Grb2 with the p85 subunit of phosphatidylinositol 3-kinase | Q28302000 | ||
| Improved green fluorescence | Q28307219 | ||
| Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth | Q28578750 | ||
| Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo | Q28586040 | ||
| Activation of phospholipase C-gamma by phosphatidylinositol 3,4,5-trisphosphate | Q28616287 | ||
| Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B | Q28646376 | ||
| Regulation of neuronal survival by the serine-threonine protein kinase Akt | Q29614185 | ||
| Improved retroviral vectors for gene transfer and expression | Q29614384 | ||
| Correlation of two-hybrid affinity data with in vitro measurements | Q29615774 | ||
| Growth factor signaling by receptor tyrosine kinases | Q29618315 | ||
| Insulin receptor substrate 1 binds two novel splice variants of the regulatory subunit of phosphatidylinositol 3-kinase in muscle and brain | Q30176985 | ||
| Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases | Q30195688 | ||
| Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt. | Q30452681 | ||
| Spatial dynamics of GFP-tagged proteins investigated by local fluorescence enhancement | Q32060735 | ||
| Electroporation-induced formation of individual calcium entry sites in the cell body and processes of adherent cells | Q33907519 | ||
| Signalling by receptor tyrosine kinases | Q34306539 | ||
| Association of the multisubstrate docking protein Gab1 with the hepatocyte growth factor receptor requires a functional Grb2 binding site involving tyrosine 1356. | Q34434985 | ||
| Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase | Q36103541 | ||
| Expression of Tie2/Tek in breast tumour vasculature provides a new marker for evaluation of tumour angiogenesis | Q36295017 | ||
| Phosphatidylinositol 3-kinase activation is mediated by high-affinity interactions between distinct domains within the p110 and p85 subunits | Q36642568 | ||
| The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity | Q36745695 | ||
| A safe packaging line for gene transfer: separating viral genes on two different plasmids | Q36865708 | ||
| Permanent cell line expressing human factor VIII-related antigen established by hybridization | Q37615209 | ||
| The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells. | Q37625629 | ||
| Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways | Q38354870 | ||
| A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain. | Q40020748 | ||
| Receptor protein-tyrosine kinases and their signal transduction pathways | Q40611453 | ||
| Phosphoinositide kinases | Q41099687 | ||
| Blood vessel formation: what is its molecular basis? | Q41288467 | ||
| SHIP, a new player in cytokine-induced signalling | Q41329918 | ||
| Isolation and characterization of an established endothelial cell line from transgenic mouse hemangiomas | Q41662591 | ||
| A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor | Q41879451 | ||
| Regulation of phosphatidylinositol 3'-kinase by tyrosyl phosphoproteins. Full activation requires occupancy of both SH2 domains in the 85-kDa regulatory subunit | Q42066856 | ||
| Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase | Q42807993 | ||
| Signaling vascular morphogenesis and maintenance | Q45058276 | ||
| Improved green fluorescent protein by molecular evolution using DNA shuffling | Q47961174 | ||
| Tie2 expression and phosphorylation in angiogenic and quiescent adult tissues | Q48044774 | ||
| The mouse tie receptor tyrosine kinase gene: expression during embryonic angiogenesis | Q48085556 | ||
| Distinct rat genes with related profiles of expression define a TIE receptor tyrosine kinase family | Q48118992 | ||
| The endothelial-specific receptor tyrosine kinase, tek, is a member of a new subfamily of receptors. | Q48122381 | ||
| Vascularization of the mouse embryo: A study of flk‐1, tek, tie, and vascular endothelial growth factor expression during development | Q52208633 | ||
| tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors | Q52230413 | ||
| Phosphatidylinositol (3,4,5)P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins | Q70787161 | ||
| Nuclear phosphatidylinositols decrease during S-phase of the cell cycle in HeLa cells | Q72302864 | ||
| Receptor-induced transient reduction in plasma membrane PtdIns(4,5)P2 concentration monitored in living cells | Q74344711 | ||
| P4510 | describes a project that uses | ImageQuant | Q112270642 |
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 4131–4140 | |
| P577 | publication date | 1998-07-01 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt | |
| P478 | volume | 18 |
| Q44206934 | A PI3-kinase signaling code for insulin-triggered insertion of glucose transporters into the plasma membrane |
| Q36320639 | A Rac switch regulates random versus directionally persistent cell migration |
| Q41574359 | A Review of Anti-Angiogenic Targets for Monoclonal Antibody Cancer Therapy |
| Q37125975 | A Role for PPARbeta/delta in Ocular Angiogenesis |
| Q28510897 | A combinatorial role of angiopoietin-1 and orphan receptor TIE1 pathways in establishing vascular polarity during angiogenesis |
| Q34448395 | A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension. |
| Q24540299 | A gene for inherited cutaneous venous anomalies ("glomangiomas") localizes to chromosome 1p21-22. |
| Q24684919 | A unique autophosphorylation site on Tie2/Tek mediates Dok-R phosphotyrosine binding domain binding and function |
| Q30480556 | Actin-myosin network reorganization breaks symmetry at the cell rear to spontaneously initiate polarized cell motility |
| Q36799036 | Activation of PI3K/Akt pathway by CD133-p85 interaction promotes tumorigenic capacity of glioma stem cells |
| Q24301574 | Adaptor ShcA protein binds tyrosine kinase Tie2 receptor and regulates migration and sprouting but not survival of endothelial cells |
| Q42799486 | An improved Akt reporter reveals intra- and inter-cellular heterogeneity and oscillations in signal transduction. |
| Q42516539 | Androgens modulate the balance between VEGF and angiopoietin expression in prostate epithelial and smooth muscle cells. |
| Q34107240 | Angiogenesis |
| Q40646268 | Angiogenic actions of angiopoietin-1 require endothelium-derived nitric oxide |
| Q24311749 | Angiopoietin 2 is a partial agonist/antagonist of Tie2 signaling in the endothelium |
| Q28640803 | Angiopoietin and Tie signaling pathways in vascular development |
| Q34355914 | Angiopoietin-1 preconditioning enhances survival and functional recovery of mesenchymal stem cell transplantation |
| Q24336384 | Angiopoietin-1-induced ubiquitylation of Tie2 by c-Cbl is required for internalization and degradation |
| Q24563486 | Biologic significance of angiopoietin-2 expression in human hepatocellular carcinoma |
| Q33968748 | Bmx tyrosine kinase has a redundant function downstream of angiopoietin and vascular endothelial growth factor receptors in arterial endothelium |
| Q37681973 | COMP-Ang1: a designed angiopoietin-1 variant with nonleaky angiogenic activity |
| Q27323236 | Coarse-grained molecular simulation of epidermal growth factor receptor protein tyrosine kinase multi-site self-phosphorylation |
| Q30670028 | Common and specific effects of TIE2 mutations causing venous malformations |
| Q42093938 | Comprehensive identification of PIP3-regulated PH domains from C. elegans to H. sapiens by model prediction and live imaging |
| Q47846359 | Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP. |
| Q35847715 | Deficiency in the p110alpha subunit of PI3K results in diminished Tie2 expression and Tie2(-/-)-like vascular defects in mice |
| Q38287809 | Deletion of the carboxyl terminus of Tie2 enhances kinase activity, signaling, and function. Evidence for an autoinhibitory mechanism. |
| Q33277127 | Differential response of lymphatic, venous and arterial endothelial cells to angiopoietin-1 and angiopoietin-2. |
| Q33807944 | Disorganized vascular structures in sporadic venous malformations: a possible correlation with balancing effect between Tie2 and TGF-β. |
| Q24535902 | Dok-R plays a pivotal role in angiopoietin-1-dependent cell migration through recruitment and activation of Pak. |
| Q44117410 | Effects of statins on angiogenesis and vasculogenesis |
| Q50107182 | Elimination of host cell PtdIns(4,5)P(2) by bacterial SigD promotes membrane fission during invasion by Salmonella |
| Q36066614 | Endoglin regulates PI3-kinase/Akt trafficking and signaling to alter endothelial capillary stability during angiogenesis |
| Q50217188 | Engineered pairs of distinct photoswitches for optogenetic control of cellular proteins |
| Q34428441 | Enzymatic detection of protein translocation |
| Q35854951 | Expression of angiogenic factors in chronic myeloid leukaemia: role of the bcr/abl oncogene, biochemical mechanisms, and potential clinical implications |
| Q35057325 | Fluorescence imaging of signaling networks. |
| Q39808150 | Functional and gene expression analysis of hTERT overexpressed endothelial cells |
| Q30784372 | Gene expression analysis of Tek/Tie2 signaling |
| Q64946471 | Genetically encoded lipid biosensors. |
| Q38358471 | Granulocyte-macrophage colony-stimulating factor signals for increased glucose transport via phosphatidylinositol 3-kinase- and hydrogen peroxide-dependent mechanisms |
| Q33814336 | Growth factor signaling pathways in vascular development |
| Q30828692 | HCPTPA, a protein tyrosine phosphatase that regulates vascular endothelial growth factor receptor-mediated signal transduction and biological activity. |
| Q28345589 | HMG-CoA reductase inhibitor mobilizes bone marrow--derived endothelial progenitor cells |
| Q28215701 | Heregulin-dependent activation of phosphoinositide 3-kinase and Akt via the ErbB2/ErbB3 co-receptor |
| Q35958188 | Human platelet lysate improves human cord blood derived ECFC survival and vasculogenesis in three dimensional (3D) collagen matrices |
| Q58451410 | Imaging and manipulating phosphoinositides in living cells |
| Q50291281 | Interaction of Tie2 and p85 of PI3K |
| Q37175153 | Lactate engages receptor tyrosine kinases Axl, Tie2, and vascular endothelial growth factor receptor 2 to activate phosphoinositide 3-kinase/Akt and promote angiogenesis |
| Q92822205 | Listeria monocytogenes Exploits Host Caveolin for Cell-to-Cell Spreading |
| Q36293644 | Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis |
| Q24313357 | Molecular basis for a direct interaction between the Syk protein-tyrosine kinase and phosphoinositide 3-kinase |
| Q34660609 | Molecular control of angiopoietin signalling |
| Q34375946 | Molecular genetics of vascular malformations |
| Q24300714 | Multiple angiopoietin recombinant proteins activate the Tie1 receptor tyrosine kinase and promote its interaction with Tie2 |
| Q28215504 | NERF2, a member of the Ets family of transcription factors, is increased in response to hypoxia and angiopoietin-1: a potential mechanism for Tie2 regulation during hypoxia |
| Q37217491 | Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation |
| Q21129332 | PI3K/AKT/mTOR Pathway in Angiogenesis |
| Q64379300 | PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects |
| Q39852386 | PTEN regulates angiogenesis through PI3K/Akt/VEGF signaling pathway in human pancreatic cancer cells |
| Q37116110 | Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells |
| Q28140934 | Phosphatidylinositol 3-kinase-dependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cells |
| Q35078016 | Phosphoinositide signaling: new tools and insights. |
| Q36983361 | Plasma Fibronectin Promotes Tumor Cell Survival and Invasion through Regulation of Tie2. |
| Q35236004 | Polyphosphoinositide binding domains: Key to inositol lipid biology. |
| Q39088749 | Quantifying lipid changes in various membrane compartments using lipid binding protein domains |
| Q27333126 | Rapamycin improves TIE2-mutated venous malformation in murine model and human subjects |
| Q40228821 | Rapid chemically induced changes of PtdIns(4,5)P2 gate KCNQ ion channels |
| Q28365924 | Rescue of the early vascular defects in Tek/Tie2 null mice reveals an essential survival function |
| Q33837107 | Selective role of a distinct tyrosine residue on Tie2 in heart development and early hematopoiesis |
| Q36462707 | Signaling and functions of angiopoietin-1 in vascular protection. |
| Q55386096 | Small Rho GTPases and the Effector VipA Mediate the Invasion of Epithelial Cells by Filamentous Legionella pneumophila. |
| Q33883982 | Small-molecule inhibitors of the PI3K signaling network |
| Q37130685 | Somatic PIK3CA mutations as a driver of sporadic venous malformations. |
| Q30481042 | Spatial sensing in fibroblasts mediated by 3' phosphoinositides |
| Q37403967 | Spatio-temporal dynamics of phosphatidylinositol-3,4,5-trisphosphate signalling. |
| Q40374532 | Stable interaction between alpha5beta1 integrin and Tie2 tyrosine kinase receptor regulates endothelial cell response to Ang-1. |
| Q36142655 | Statin mediated protection of the ischemic myocardium |
| Q52532836 | Structure and function of phosphoinositide 3-kinases. |
| Q27628323 | Structure of the Tie2 RTK domain: self-inhibition by the nucleotide binding loop, activation loop, and C-terminal tail |
| Q40846784 | Studies of signal transduction events using chimeras to green fluorescent protein |
| Q39645531 | TEK/Tie2 Is a Novel Gene Involved in Endoplasmic Reticulum Stress |
| Q64946532 | Targeting Protein Kinases to Enhance the Response to anti-PD-1/PD-L1 Immunotherapy. |
| Q38990050 | Targeting Tie2 for Treatment of Diabetic Retinopathy and Diabetic Macular Edema |
| Q33688733 | The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals |
| Q33688482 | The RNA binding protein hnRNP-K mediates post-transcriptional regulation of uncoupling protein-2 by angiopoietin-1 |
| Q28144156 | The SH2 inositol 5-phosphatase Ship1 is recruited in an SH2-dependent manner to the erythropoietin receptor |
| Q30157772 | The carboxyl-terminal SH3 domain of the mammalian adaptor CrkII promotes internalization of Listeria monocytogenes through activation of host phosphoinositide 3-kinase |
| Q34323637 | The endothelial receptor tyrosine kinase Tie1 activates phosphatidylinositol 3-kinase and Akt to inhibit apoptosis. |
| Q37486191 | The role of the Angiopoietins in vascular morphogenesis. |
| Q30541353 | The small GTPase HRas shapes local PI3K signals through positive feedback and regulates persistent membrane extension in migrating fibroblasts |
| Q38710732 | The untapped potential of tyrosine-based G protein signaling |
| Q34205564 | Tie receptors: new modulators of angiogenic and lymphangiogenic responses |
| Q24305656 | Tie-2-dependent activation of RhoA and Rac1 participates in endothelial cell motility triggered by angiopoietin-1 |
| Q34116086 | Tie2 in tumor endothelial signaling and survival: implications for antiangiogenic therapy |
| Q39466800 | Tyrosine phosphorylation of the Gα-interacting protein GIV promotes activation of phosphoinositide 3-kinase during cell migration |
| Q34508473 | Unravelling novel intracellular pathways in cell-based assays |
| Q27025402 | Vascular anomalies: from genetics toward models for therapeutic trials |
| Q36808725 | Visualization and manipulation of phosphoinositide dynamics in live cells using engineered protein domains. |
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