Ubiquitin dimers control the hydrolase activity of UCH-L3

scientific article

Ubiquitin dimers control the hydrolase activity of UCH-L3 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.NEUINT.2008.12.013
P698PubMed publication ID19154770

P2093author name stringKeiji Wada
Mikako Sakurai
Rieko Setsuie
Yuriko Sakaguchi
P2860cites workThe ubiquitin-proteasome proteolytic pathway: destruction for the sake of constructionQ24292709
A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cellsQ24297079
A ubiquitin ligase complex assembles linear polyubiquitin chainsQ24305030
Substrate binding and catalysis by ubiquitin C-terminal hydrolases: identification of two active site residuesQ24313165
Substrate specificity of deubiquitinating enzymes: ubiquitin C-terminal hydrolasesQ24320112
Crystal structure of a deubiquitinating enzyme (human UCH-L3) at 1.8 A resolutionQ24532257
Quantitative studies of the growth of mouse embryo cells in culture and their development into established linesQ24683034
The ubiquitin systemQ27860803
Regulation of ubiquitin-dependent processes by deubiquitinating enzymesQ28257517
The roles of intracellular protein-degradation pathways in neurodegenerationQ28269322
Proteasome-independent functions of ubiquitin in endocytosis and signalingQ28282959
A genomic and functional inventory of deubiquitinating enzymesQ28284911
Role of ubiquitin carboxy terminal hydrolase-L1 in neural cell apoptosis induced by ischemic retinal injury in vivoQ28585083
Loss of Uch-L1 and Uch-L3 leads to neurodegeneration, posterior paralysis and dysphagiaQ28589057
Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuronQ28589324
Expression and functional analysis of Uch-L3 during mouse developmentQ28593683
The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolaseQ28941761
Protein regulation by monoubiquitinQ29620221
Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad miceQ30764264
Cleavage of the C-terminus of NEDD8 by UCH-L3.Q31990233
The binding site for UCH-L3 on ubiquitin: mutagenesis and NMR studies on the complex between ubiquitin and UCH-L3.Q33876794
Weighing in on ubiquitin: the expanding role of mass-spectrometry-based proteomicsQ34015771
The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibilityQ34157005
Structure of the ubiquitin hydrolase UCH-L3 complexed with a suicide substrateQ34365924
Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1Q34502063
Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteinsQ34551647
Photoreceptor cell apoptosis in the retinal degeneration of Uchl3-deficient miceQ35221892
Lingering mysteries of ubiquitin-chain assemblyQ36368593
The functions of UCH-L1 and its relation to neurodegenerative diseasesQ36856806
The ubiquitin-proteasome pathway in health and disease of the nervous systemQ36976865
Aberrant molecular properties shared by familial Parkinson's disease-associated mutant UCH-L1 and carbonyl-modified UCH-L1.Q40016575
Alterations of structure and hydrolase activity of parkinsonism-associated human ubiquitin carboxyl-terminal hydrolase L1 variantsQ44410269
An engineered 800 kilobase deletion of Uchl3 and Lmo7 on mouse chromosome 14 causes defects in viability, postnatal growth and degeneration of muscle and retinaQ44449717
Potentiation of ATP-induced currents due to the activation of P2X receptors by ubiquitin carboxy-terminal hydrolase L1.Q45269239
Developmental regulation of ubiquitin C-terminal hydrolase isozyme expression during spermatogenesis in miceQ47764488
The ubiquitin pathway in Parkinson's diseaseQ48015939
Reduction in memory in passive avoidance learning, exploratory behaviour and synaptic plasticity in mice with a spontaneous deletion in the ubiquitin C-terminal hydrolase L1 geneQ48359758
Ubiquitin C-terminal hydrolase L3 (Uchl3) is involved in working memoryQ48892814
Dopaminergic neuronal loss in transgenic mice expressing the Parkinson's disease-associated UCH-L1 I93M mutant.Q54581994
Nonhydrolyzable diubiquitin analogues are inhibitors of ubiquitin conjugation and deconjugationQ74138474
Ubiquitin C-terminal hydrolase L1 regulates the morphology of neural progenitor cells and modulates their differentiationQ82053209
P433issue5-6
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
ubiquitin bindingQ14864232
Ubiquitin C-terminal hydrolase L3Q21126400
P304page(s)314-21
P577publication date2009-01-01
P1433published inNeurochemistry InternationalQ7002160
P1476titleUbiquitin dimers control the hydrolase activity of UCH-L3
P478volume54

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cites work (P2860)
Q47158922A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN.
Q37673274Basic mechanisms of neurodegeneration: a critical update
Q37596297Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis
Q33810416Effect of ubiquitin carboxy-terminal hydrolase 37 on apoptotic in A549 cells
Q34300609Profiling ubiquitin linkage specificities of deubiquitinating enzymes with branched ubiquitin isopeptide probes
Q34999535Recent advances in our understanding of neurodegeneration
Q57956865The insulin degrading enzyme activates ubiquitin and promotes the formation of K48 and K63 diubiquitin
Q55416803UCHL3 Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling TDP1 Proteostasis.
Q43180105Ubiquitin C-terminal hydrolases cleave isopeptide- and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers
Q28941247Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling

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