| scholarly article | Q13442814 |
| P356 | DOI | 10.1093/HMG/DDN037 |
| P8608 | Fatcat ID | release_bwzdrkjxdvh7njvo4vggzwet6a |
| P698 | PubMed publication ID | 18250096 |
| P5875 | ResearchGate publication ID | 5602478 |
| P50 | author | Shunsuke Aoki | Q67123720 |
| P2093 | author name string | Keiji Wada | |
| Mikako Sakurai | |||
| Rieko Setsuie | |||
| Aiko Kinugawa | |||
| Takeshi Mitsui | |||
| Tomohiro Kabuta | |||
| Kenko Uchida | |||
| P2860 | cites work | Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity | Q24290192 |
| Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis | Q24299487 | ||
| Substrate specificity of deubiquitinating enzymes: ubiquitin C-terminal hydrolases | Q24320112 | ||
| Natural beta-sheet proteins use negative design to avoid edge-to-edge aggregation | Q24530946 | ||
| Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide | Q28131750 | ||
| Degradation of Amyotrophic Lateral Sclerosis-linked Mutant Cu,Zn-Superoxide Dismutase Proteins by Macroautophagy and the Proteasome | Q56777088 | ||
| Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria | Q28270155 | ||
| Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death | Q28287762 | ||
| Insulin receptor substrate-3 functions as transcriptional activator in the nucleus | Q28574967 | ||
| Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuron | Q28589324 | ||
| The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase | Q28941761 | ||
| pEF-BOS, a powerful mammalian expression vector | Q29547606 | ||
| Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy | Q29614178 | ||
| Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice | Q30476254 | ||
| Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice | Q30764264 | ||
| Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1. | Q31101732 | ||
| Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein | Q31120123 | ||
| The chaperonin TRiC controls polyglutamine aggregation and toxicity through subunit-specific interactions | Q33693921 | ||
| Role of reactive aldehyde in cardiovascular diseases | Q34006248 | ||
| The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility | Q34157005 | ||
| Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1 | Q34502063 | ||
| Ubiquitin hydrolase Uch-L1 rescues beta-amyloid-induced decreases in synaptic function and contextual memory | Q34559237 | ||
| Oxidative stress and nitration in neurodegeneration: cause, effect, or association? | Q35047296 | ||
| Photoreceptor cell apoptosis in the retinal degeneration of Uchl3-deficient mice | Q35221892 | ||
| Differential regulation of microtubule dynamics by three- and four-repeat tau: implications for the onset of neurodegenerative disease | Q35234889 | ||
| Histidine and lysine as targets of oxidative modification | Q35602234 | ||
| Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis. | Q35818148 | ||
| Differential utilization of beta-tubulin isotypes in differentiating neurites | Q36221310 | ||
| Peripheral neuropathy induced by microtubule-stabilizing agents. | Q36436422 | ||
| Proteasomal dysfunction: a common feature of neurodegenerative diseases? Implications for the environmental origins of neurodegeneration | Q36620575 | ||
| Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease | Q37671552 | ||
| Interaction between familial amyotrophic lateral sclerosis (ALS)-linked SOD1 mutants and the dynein complex | Q40150834 | ||
| Aberrantly increased hydrophobicity shared by mutants of Cu,Zn-superoxide dismutase in familial amyotrophic lateral sclerosis. | Q40409233 | ||
| UCH-L1 aggresome formation in response to proteasome impairment indicates a role in inclusion formation in Parkinson's disease | Q40540062 | ||
| Cellular toxicity of polyglutamine expansion proteins: mechanism of transcription factor deactivation | Q40540661 | ||
| Oxidation of free amino acids and amino acid residues in proteins by radiolysis and by metal-catalyzed reactions | Q40835305 | ||
| Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein | Q42491661 | ||
| Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans | Q43868792 | ||
| Alterations of structure and hydrolase activity of parkinsonism-associated human ubiquitin carboxyl-terminal hydrolase L1 variants | Q44410269 | ||
| Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases | Q44727052 | ||
| UCHL-1 is not a Parkinson's disease susceptibility gene | Q46922093 | ||
| Stabilization of hyperdynamic microtubules is neuroprotective in amyotrophic lateral sclerosis | Q46977479 | ||
| UCHL1 is a Parkinson's disease susceptibility gene | Q47866612 | ||
| The ubiquitin pathway in Parkinson's disease | Q48015939 | ||
| Reduction in memory in passive avoidance learning, exploratory behaviour and synaptic plasticity in mice with a spontaneous deletion in the ubiquitin C-terminal hydrolase L1 gene | Q48359758 | ||
| Ubiquitin carboxyl-terminal hydrolase (PGP 9.5) is selectively present in ubiquitinated inclusion bodies characteristic of human neurodegenerative diseases | Q48960752 | ||
| Cytosolic chaperonin prevents polyglutamine toxicity with altering the aggregation state. | Q52573641 | ||
| Dopaminergic neuronal loss in transgenic mice expressing the Parkinson's disease-associated UCH-L1 I93M mutant. | Q54581994 | ||
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Parkinson's disease | Q11085 |
| P304 | page(s) | 1482-1496 | |
| P577 | publication date | 2008-02-04 | |
| P1433 | published in | Human Molecular Genetics | Q2720965 |
| P1476 | title | Aberrant molecular properties shared by familial Parkinson's disease-associated mutant UCH-L1 and carbonyl-modified UCH-L1. | |
| P478 | volume | 17 |
| Q38212199 | Aberrant autophagy and parkinsonism: does correction rescue from disease progression? |
| Q35676668 | Aberrant interaction between Parkinson disease-associated mutant UCH-L1 and the lysosomal receptor for chaperone-mediated autophagy |
| Q48297662 | Association of ubiquitin carboxy-terminal hydrolase-L1 in cerebrospinal fluid with clinical severity in a cohort of patients with Guillain-Barré syndrome |
| Q38108538 | Could dysregulation of UPS be a common underlying mechanism for cancer and neurodegeneration? Lessons from UCHL1. |
| Q33859389 | Cyclopentenone prostaglandin-induced unfolding and aggregation of the Parkinson disease-associated UCH-L1. |
| Q38035191 | Defective autophagy in Parkinson's disease: role of oxidative stress. |
| Q26801232 | Deubiquitinating enzymes in cellular signaling and disease regulation |
| Q30317812 | Heterogeneous expression and functional relevance of the ubiquitin carboxyl-terminal hydrolase L1 in melanoma |
| Q39760458 | Identification of autoantigens specific for systemic lupus erythematosus with central nervous system involvement |
| Q33724954 | In vivo transduction of neurons with TAT-UCH-L1 protects brain against controlled cortical impact injury |
| Q38872092 | Inhibition of UCH-L1 in oligodendroglial cells results in microtubule stabilization and prevents α-synuclein aggregate formation by activating the autophagic pathway: implications for multiple system atrophy |
| Q26765816 | It Is All about (U)biquitin: Role of Altered Ubiquitin-Proteasome System and UCHL1 in Alzheimer Disease |
| Q39046910 | KSHV LANA and EBV LMP1 induce the expression of UCH-L1 following viral transformation |
| Q38972179 | Life and death in the trash heap: The ubiquitin proteasome pathway and UCHL1 in brain aging, neurodegenerative disease and cerebral Ischemia |
| Q36810938 | Lysosomal putative RNA transporter SIDT2 mediates direct uptake of RNA by lysosomes |
| Q34043163 | Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death. |
| Q33719548 | Modelling the role of UCH-L1 on protein aggregation in age-related neurodegeneration |
| Q41598067 | Modification of ubiquitin-C-terminal hydrolase-L1 by cyclopentenone prostaglandins exacerbates hypoxic injury. |
| Q35193829 | N-terminal truncated UCH-L1 prevents Parkinson's disease associated damage |
| Q39556264 | PU.1-dependent regulation of UCH L1 expression in B-lymphoma cells |
| Q37723226 | Parkinson disease: a role for autophagy? |
| Q36129390 | Protein carbonylation and metabolic control systems |
| Q89355462 | Proteomic Analysis of Hippocampus in a Mouse Model of Depression Reveals Neuroprotective Function of Ubiquitin C-terminal Hydrolase L1 (UCH-L1) via Stress-induced Cysteine Oxidative Modifications |
| Q37704633 | S-nitrosylation of UCHL1 induces its structural instability and promotes α-synuclein aggregation. |
| Q28396109 | Small changes huge impact: the role of protein posttranslational modifications in cellular homeostasis and disease |
| Q30368088 | Structure of transmembrane domain of lysosome-associated membrane protein type 2a (LAMP-2A) reveals key features for substrate specificity in chaperone-mediated autophagy. |
| Q34774553 | The ubiquitin C-terminal hydrolase L1 (UCH-L1) C terminus plays a key role in protein stability, but its farnesylation is not required for membrane association in primary neurons |
| Q30421989 | The ubiquitin-specific protease 14 (USP14) is a critical regulator of long-term memory formation. |
| Q38829786 | UCH-L1 Inhibition Decreases the Microtubule-Binding Function of Tau Protein |
| Q28118734 | UCHL1 deficiency exacerbates human islet amyloid polypeptide toxicity in β-cells: evidence of interplay between the ubiquitin/proteasome system and autophagy |
| Q36812366 | Ubiquitin C-terminal hydrolase L1 (UCH-L1) acts as a novel potentiator of cyclin-dependent kinases to enhance cell proliferation independently of its hydrolase activity |
| Q26741828 | Ubiquitin C-terminal hydrolase L1 (UCH-L1): structure, distribution and roles in brain function and dysfunction |
| Q39257016 | Ubiquitin C-terminal hydrolase-L1 (UCH-L1) as a therapeutic and diagnostic target in neurodegeneration, neurotrauma and neuro-injuries |
| Q24318689 | Ubiquitin dimers control the hydrolase activity of UCH-L3 |
| Q39738670 | Ubiquitin editing enzyme UCH L1 and microtubule dynamics: implication in mitosis |
| Q34448671 | β-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency |
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