Placental overgrowth in mice lacking the imprinted gene Ipl

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Placental overgrowth in mice lacking the imprinted gene Ipl is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2002PNAS...99.7490F
P356DOI10.1073/PNAS.122039999
P8608Fatcat IDrelease_i6dphqti4jgotf3zqixs52zh2i
P3181OpenCitations bibliographic resource ID4061961
P932PMC publication ID124258
P698PubMed publication ID12032310
P5875ResearchGate publication ID11340818

P50authorWolf ReikQ15994704
Lorraine ClarkQ64858601
Anjana SaxenaQ77545530
P2093author name stringBenjamin Tycko
Chi-Ming Li
Dale Frank
Raymond Musalo
Thomas Ludwig
Weiwei Fortino
Wenxian Wang
P2860cites workA novel pleckstrin homology-related gene family defined by Ipl/Tssc3, TDAG51, and Tih1: tissue-specific expression, chromosomal location, and parental imprintingQ22010925
The IPL gene on chromosome 11p15.5 is imprinted in humans and mice and is similar to TDAG51, implicated in Fas expression and apoptosisQ24318274
Signal-dependent membrane targeting by pleckstrin homology (PH) domainsQ24532099
Genomic imprinting of a human apoptosis gene homologue, TSSC3Q28264509
Genomic imprinting in mammalian development: a parental tug-of-warQ28278146
Disruption of imprinting caused by deletion of the H19 gene region in miceQ28287765
Essential role of Mash-2 in extraembryonic developmentQ28508129
Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and developmentQ28512118
Defects of the chorioallantoic placenta in mouse RXRalpha null fetusesQ28587837
Placental failure in mice lacking the homeobox gene Dlx3Q28591080
Esx1 is an X-chromosome-imprinted regulator of placental development and fetal growthQ28591932
Role of insulin-like growth factors in embryonic and postnatal growthQ29620034
Beckwith-Wiedemann syndrome: imprinting in clusters revisitedQ33838090
Genetic insights into trophoblast differentiation and placental morphogenesisQ33954393
Mouse mutant embryos overexpressing IGF-II exhibit phenotypic features of the Beckwith-Wiedemann and Simpson-Golabi-Behmel syndromesQ35197831
Oppositely imprinted genes p57(Kip2) and igf2 interact in a mouse model for Beckwith-Wiedemann syndromeQ35209963
Isolation and characterization of a novel trophoblast-specific cDNA in the mouseQ36440030
Genomic imprinting and the strange case of the insulin-like growth factor II receptorQ37165552
Genomic imprinting of Mash2, a mouse gene required for trophoblast developmentQ38298288
The pleckstrin homology and phosphotyrosine binding domains of insulin receptor substrate 1 mediate inhibition of apoptosis by insulinQ39576638
Transactivation of Igf2 in a mouse model of Beckwith-Wiedemann syndrome.Q41066237
Disruption of an imprinted gene cluster by a targeted chromosomal translocation in miceQ42658164
Lack of correlation between placenta and offspring size in mouse interspecific crossesQ47258782
Epigenetic instability in ES cells and cloned miceQ48882976
The sins of the fathers and mothers: genomic imprinting in mammalian development.Q50532990
Parental origin-specific developmental defects in mice with uniparental disomy for chromosome 12.Q52164578
Conditional mutagenesis in mice with heat shock promoter-driven cre transgenes.Q52169941
Parental imprinting of the mouse insulin-like growth factor II gene.Q55052428
Placentomegaly in Cloned Mouse Concepti Caused by Expansion of the Spongiotrophoblast Layer1Q61984431
Ultrastructural observations on the maturation of the placental labyrinth of the golden hamster (days 10 to 16 of gestation)Q66964211
GENETIC AND ENVIRONMENTAL EFFECTS ON FOETAL AND PLACENTAL GROWTH IN MICEQ77221220
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectPleckstrin homology like domain, family A, member 2Q21986251
P304page(s)7490-5
P577publication date2002-05-28
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titlePlacental overgrowth in mice lacking the imprinted gene Ipl
P478volume99

Reverse relations

cites work (P2860)
Q34285755A genomic imprinting defect in mice traced to a single gene
Q34364011Aberrant growth and pattern formation in Peromyscus hybrid placental development
Q36324388Abnormal gene expression in regular and aggregated somatic cell nuclear transfer placentas
Q64889113Abundances of placental imprinted genes CDKN1C, PHLDA2 and IGF-2 are related to low birth weight and early catch-up growth in full-term infants born small for gestational age.
Q37165888Acephalous lamb from an in vitro-produced sheep embryo
Q35320849Altered imprinted gene expression and methylation patterns in mid-gestation aborted cloned porcine fetuses and placentas
Q35754088Assisted reproduction causes placental maldevelopment and dysfunction linked to reduced fetal weight in mice.
Q33828515Autophagy and apoptosis: parent-of-origin genome-dependent mechanisms of cellular self-destruction
Q34442748BACs as tools for the study of genomic imprinting
Q38089794Beckwith-Wiedemann and Silver-Russell syndromes: opposite developmental imbalances in imprinted regulators of placental function and embryonic growth
Q40462752Biallelic expression of Tssc4, Nap1l4, Phlda2 and Osbpl5 in adult cattle.
Q33285306Cdkn1c (p57Kip2) is the major regulator of embryonic growth within its imprinted domain on mouse distal chromosome 7.
Q33997704Characterisation of marsupial PHLDA2 reveals eutherian specific acquisition of imprinting
Q24647126Characterization of conserved and nonconserved imprinted genes in swine
Q35661043Cloning and transgenesis in mammals: implications for xenotransplantation
Q34409829Co-evolution of X-chromosome inactivation and imprinting in mammals
Q34979379Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation
Q36383223DNA methylation in the human placenta and fetal growth (review).
Q48798172Delta-like 1 homolog in Capra hircus: molecular characteristics, expression pattern and phylogeny
Q36166995Determinants of trophoblast lineage and cell subtype specification in the mouse placenta
Q33889437Developmental stage-specific imprinting of IPL in domestic pigs (Sus scrofa).
Q47701588Different molecular mechanisms underlie placental overgrowth phenotypes caused by interspecies hybridization, cloning, and Esx1 mutation
Q28279818Elevated placental expression of the imprinted PHLDA2 gene is associated with low birth weight
Q36311154Epigenetic modification is central to genome reprogramming in somatic cell nuclear transfer.
Q34734556Epigenetic regulation of placental endocrine lineages and complications of pregnancy
Q37801493Epigenetics and the placenta
Q50736910Establishment of a new diagnostic method for hydropic villi by using TSSC3 antibody.
Q54634225Expression and functional analysis of genes deregulated in mouse placental overgrowth models: Car2 and Ncam1.
Q59797945Fetal growth restriction in a genetic model of sporadic Beckwith-Wiedemann syndrome
Q36065882Genomic imprinting and epigenetic control of development
Q91596236Genomic imprinting and its effects on postnatal growth and adult metabolism
Q37715275Genomic imprinting in development, growth, behavior and stem cells
Q21145256Genomic imprinting in mammals: emerging themes and established theories
Q36436530Genomic imprinting in the placenta
Q37992688Health during pregnancy and beyond: Fetal trophoblast cells as chief co-ordinators of intrauterine growth and reproductive success
Q28510837Hectd1 is required for development of the junctional zone of the placenta
Q36166920Igf2 ligand dependency of Pten(+/-) developmental and tumour phenotypes in the mouse
Q36436584Imprinted genes and their role in human fetal growth.
Q36436588Imprinted genes in placental growth and obstetric disorders
Q90557455Imprinted genes influencing the quality of maternal care
Q28306944Imprinted genes, placental development and fetal growth
Q35043723Imprinting and disease
Q37543706Imprinting and extraembryonic tissues-mom takes control
Q41208500Increased dosage of the imprinted Ascl2 gene restrains two key endocrine lineages of the mouse Placenta
Q34241144Isolating the role of elevated Phlda2 in asymmetric late fetal growth restriction in mice
Q35943539Lentivirus-mediated PHLDA2 overexpression inhibits trophoblast proliferation, migration and invasion, and induces apoptosis
Q28506802Loss of Cited2 affects trophoblast formation and vascularization of the mouse placenta
Q35178408Loss of inherited genomic imprints in mice leads to severe disruption in placental lipid metabolism
Q33932918Male CD81 knockout genotype disrupts Mendelian distribution of offspring.
Q36510078Maternal DNA Methylation Regulates Early Trophoblast Development
Q56889416Maternal care boosted by paternal imprinting in mammals
Q35877833Maternal inheritance of a promoter variant in the imprinted PHLDA2 gene significantly increases birth weight
Q33789139Maternal psychosocial stress during pregnancy and placenta weight: evidence from a national cohort study
Q47172204Maternally-inherited Grb10 reduces placental size and efficiency
Q37391254Microarray analysis of prothrombin knockdown in zebrafish
Q52585697Molecular pathogenesis of pancreatic ductal adenocarcinoma: impact of passenger strand of pre-miR-148a on gene regulation.
Q36267711Nik-related kinase regulates trophoblast proliferation and placental development by modulating AKT phosphorylation
Q57230571Origin and characteristics of glycogen cells in the developing murine placenta
Q55118944PATL2 is a key actor of oocyte maturation whose invalidation causes infertility in women and mice.
Q24309413PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt
Q58738098PHLDA1, another PHLDA family protein that inhibits Akt
Q33767655PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors
Q35737547Partial Loss of Genomic Imprinting Reveals Important Roles for Kcnq1 and Peg10 Imprinted Domains in Placental Development
Q28591355Partial loss of Ascl2 function affects all three layers of the mature placenta and causes intrauterine growth restriction
Q83004761Paternal age as a risk factor for low birthweight
Q37484070Paternally expressed, imprinted insulin-like growth factor-2 in chorionic villi correlates significantly with birth weight
Q33692490Phosphatidylinositol 3 kinase modulation of trophoblast cell differentiation
Q28206637Phosphoinositide binding by the pleckstrin homology domains of Ipl and Tih1
Q59030457Piece of cake
Q28507167Plac1 (placenta-specific 1) is essential for normal placental and embryonic development
Q28384560Placental DNA hypomethylation in association with particulate air pollution in early life
Q30245567Placental Origins of Chronic Disease
Q47421227Pleckstrin homology-like domain family A, member 3 (PHLDA3) deficiency improves islets engraftment through the suppression of hypoxic damage
Q28513019Protocadherin 12 deficiency alters morphogenesis and transcriptional profile of the placenta
Q36436592Regulation of growth and metabolism by imprinted genes
Q35058363Regulation of supply and demand for maternal nutrients in mammals by imprinted genes.
Q36852705Relationship between placental expression of the imprinted PHLDA2 gene, intrauterine skeletal growth and childhood bone mass
Q33575632Rescue of placental phenotype in a mechanistic model of Beckwith-Wiedemann syndrome
Q24797256The Tnfrh1 (Tnfrsf23) gene is weakly imprinted in several organs and expressed at the trophoblast-decidua interface
Q36302091The cumulative effect of assisted reproduction procedures on placental development and epigenetic perturbations in a mouse model.
Q43704012The effect of paternal age on fetal birth outcomes
Q38848685The expression of the imprinted gene pleckstrin homology-like domain family A member 2 in placental tissues of preeclampsia and its effects on the proliferation, migration and invasion of trophoblast cells JEG-3.
Q33628787The importance of imprinting in the human placenta.
Q28593841The imprinted Phlda2 gene modulates a major endocrine compartment of the placenta to regulate placental demands for maternal resources
Q28512597The imprinted Phlda2 gene regulates extraembryonic energy stores
Q37278762The interval between Ins2 and Ascl2 is dispensable for imprinting centre function in the murine Beckwith-Wiedemann region
Q36466639The maternally expressed gene Tssc3 regulates the expression of MASH2 transcription factor in mouse trophoblast stem cells through the AKT-Sp1 signaling pathway
Q37284688The placental imprintome and imprinted gene function in the trophoblast glycogen cell lineage
Q28083223The role and interaction of imprinted genes in human fetal growth
Q28505544Transcriptional repressor erf determines extraembryonic ectoderm differentiation
Q33523184Transcriptomic profiling of bovine IVF embryos revealed candidate genes and pathways involved in early embryonic development
Q34705762Uncovering gene regulatory networks during mouse fetal germ cell development
Q38246516What does genetics tell us about imprinting and the placenta connection?

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