Cdkn1c (p57Kip2) is the major regulator of embryonic growth within its imprinted domain on mouse distal chromosome 7.

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Cdkn1c (p57Kip2) is the major regulator of embryonic growth within its imprinted domain on mouse distal chromosome 7. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1186/1471-213X-7-53
P932PMC publication ID1891291
P698PubMed publication ID17517131
P5875ResearchGate publication ID6315767

P50authorAzim SuraniQ793786
Rosalind JohnQ52693633
Simon J. TunsterQ55816320
P2093author name stringSheila C Barton
Michelle D Wood
Stuart C Andrews
P2860cites workIMPT1, an imprinted gene similar to polyspecific transporter and multi-drug resistance genesQ24317066
The IPL gene on chromosome 11p15.5 is imprinted in humans and mice and is similar to TDAG51, implicated in Fas expression and apoptosisQ24318274
Placental overgrowth in mice lacking the imprinted gene IplQ24530568
Imprinting of the gene encoding a human cyclin-dependent kinase inhibitor, p57KIP2, on chromosome 11p15Q24568014
Association of in vitro fertilization with Beckwith-Wiedemann syndrome and epigenetic alterations of LIT1 and H19Q24615581
Beckwith-Wiedemann syndrome and assisted reproduction technology (ART)Q24678681
New p57KIP2 mutations in Beckwith-Wiedemann syndromeQ28252299
Genomic imprinting in mammalian development: a parental tug-of-warQ28278146
An imprinted gene p57KIP2 is mutated in Beckwith-Wiedemann syndromeQ28292249
Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distributionQ28300442
p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor geneQ28300451
p57(Kip2) cooperates with Nurr1 in developing dopamine cellsQ28587845
Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1Q28589840
Loss of the maternal H19 gene induces changes in Igf2 methylation in both cis and transQ28594559
A gene expression atlas of the central nervous system based on bacterial artificial chromosomesQ29617753
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)Q29619910
Genomic imprinting of IGF2, p57(KIP2) and PEG1/MEST in a marsupial, the tammar wallabyQ33210926
Children after in vitro fertilization. An overview of the literatureQ33688184
Imprinted Nesp55 influences behavioral reactivity to novel environmentsQ33724476
Epigenotype-phenotype correlations in Beckwith-Wiedemann syndromeQ33927299
Genomic imprinting, mammalian evolution, and the mystery of egg-laying mammals.Q33967141
Monotreme IGF2 expression and ancestral origin of genomic imprintingQ34085483
Placental-specific IGF-II is a major modulator of placental and fetal growth.Q34135795
Differential activity of maternally and paternally derived chromosome regions in miceQ34198480
Xlr3b is a new imprinted candidate for X-linked parent-of-origin effects on cognitive function in miceQ34420540
Interactions between imprinting effects in the mouseQ34567123
Disruption of the imprinted Grb10 gene leads to disproportionate overgrowth by an Igf2-independent mechanismQ35167917
Oppositely imprinted genes p57(Kip2) and igf2 interact in a mouse model for Beckwith-Wiedemann syndromeQ35209963
Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2.Q35211749
Coding mutations in p57KIP2 are present in some cases of Beckwith-Wiedemann syndrome but are rare or absent in Wilms tumorsQ35249129
Low frequency of p57KIP2 mutation in Beckwith-Wiedemann syndromeQ35249196
Imprinting and assisted reproductive technology.Q36088926
Imprinted genes and their role in human fetal growth.Q36436584
Imprinted genes in placental growth and obstetric disordersQ36436588
Regulation of growth and metabolism by imprinted genesQ36436592
Phenotypic alterations in insulin-deficient mutant mice.Q36766264
The centromeric 11p15 imprinting centre is also involved in Silver-Russell syndromeQ37004473
Genomic imprinting and the strange case of the insulin-like growth factor II receptorQ37165552
Genomic imprinting of p57KIP2, a cyclin-dependent kinase inhibitor, in mouseQ38291049
Genomic imprinting of Mash2, a mouse gene required for trophoblast developmentQ38298288
Preterm delivery, low birthweight and small-for-gestational-age in liveborn singleton babies resulting from in-vitro fertilizationQ38977654
The role of the insulin-like growth factors in the central nervous systemQ41301869
IGF-I is required for normal embryonic growth in miceQ41510465
A role for the Ras signalling pathway in synaptic transmission and long-term memoryQ42833586
The two-domain hypothesis in Beckwith-Wiedemann syndromeQ43204600
Non-imprinted Igf2r expression decreases growth and rescues the Tme mutation in mice.Q43580738
Exposure of mouse preimplantation embryos to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) alters the methylation status of imprinted genes H19 and Igf2.Q44762564
The imprinted signaling protein XL alpha s is required for postnatal adaptation to feeding.Q44992718
Low and very low birth weight in infants conceived with use of assisted reproductive technologyQ47191285
A human p57(KIP2) transgene is not activated by passage through the maternal mouse germlineQ47915161
Abnormal maternal behaviour and growth retardation associated with loss of the imprinted gene MestQ48016474
Regulation of maternal behavior and offspring growth by paternally expressed Peg3.Q48243147
Cellular pattern of type-I insulin-like growth factor receptor gene expression during maturation of the rat brain: comparison with insulin-like growth factors I and II.Q48549457
A transgenic approach to studying imprinted genes: modified BACs and PACsQ48555883
Imprinted expression of neuronatin from modified BAC transgenes reveals regulation by distinct and distant enhancersQ48560971
Distant cis-elements regulate imprinted expression of the mouse p57( Kip2) (Cdkn1c) gene: implications for the human disorder, Beckwith--Wiedemann syndrome.Q48561025
Neurobehavioral and electroencephalographic abnormalities in Ube3a maternal-deficient miceQ48661423
Disruption of imprinting in cloned mouse fetuses from embryonic stem cells.Q52099573
p57(Kip2) regulates progenitor cell proliferation and amacrine interneuron development in the mouse retina.Q52166705
Imprinting and the initiation of gene silencing in the germ line.Q52187741
Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development.Q52195138
Parental imprinting of the mouse insulin-like growth factor II gene.Q55052428
Embryological and molecular investigations of parental imprinting on mouse chromosome 7.Q55052972
The two-domain hypothesis in Beckwith–Wiedemann syndrome: autonomous imprinting of the telomeric domain of the distal chromosome 7 clusterQ58134238
Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith–Wiedemann syndromeQ58236969
Allelic expression of IGF2 in marsupials and birdsQ73285233
Mice lacking a CDK inhibitor, p57Kip2, exhibit skeletal abnormalities and growth retardationQ73580769
Genetics of mouse growthQ77684683
Epigenetic risks related to assisted reproductive technologies: epigenetics, imprinting, ART and icebergs?Q79330767
Placental growth retardation due to loss of imprinting of Phlda2Q80489018
P407language of work or nameEnglishQ1860
P304page(s)53
P577publication date2007-05-21
P1433published inBMC Developmental BiologyQ15761839
P1476titleCdkn1c (p57Kip2) is the major regulator of embryonic growth within its imprinted domain on mouse distal chromosome 7.
P478volume7

Reverse relations

cites work (P2860)
Q48238419A p57 conditional mutant allele that allows tracking of p57-expressing cells
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Q35952569Cdkn1c Boosts the Development of Brown Adipose Tissue in a Murine Model of Silver Russell Syndrome
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Q92563376Imprinted Cdkn1c genomic locus cell-autonomously promotes cell survival in cerebral cortex development
Q37033645Knockdown of CDKN1C (p57(kip2)) and PHLDA2 results in developmental changes in bovine pre-implantation embryos
Q58745215Loss of Imprinting of Protects against Age and Diet-Induced Obesity
Q39388927Mutations in the PCNA-binding site of CDKN1C inhibit cell proliferation by impairing the entry into S phase
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Q81152665Neonatal diabetes mellitus
Q35737547Partial Loss of Genomic Imprinting Reveals Important Roles for Kcnq1 and Peg10 Imprinted Domains in Placental Development
Q28591355Partial loss of Ascl2 function affects all three layers of the mature placenta and causes intrauterine growth restriction
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Q37634526Visualizing Changes in Cdkn1c Expression Links Early-Life Adversity to Imprint Mis-regulation in Adults

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