The IPL gene on chromosome 11p15.5 is imprinted in humans and mice and is similar to TDAG51, implicated in Fas expression and apoptosis

scientific article

The IPL gene on chromosome 11p15.5 is imprinted in humans and mice and is similar to TDAG51, implicated in Fas expression and apoptosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/HMG/6.12.2021
P698PubMed publication ID9328465

P50authorColum WalshQ62740262
P2093author name stringQ Wang
L Zhao
D Frank
B Tycko
L Yuan
N Qian
D Dao
D O'Keefe
M Keating
P2860cites workAllele specific inactivation of insulin 1 and 2, in the mouse yolk sac, indicates imprintingQ48084682
Imprinted chromosomal regions of the human genome display sex-specific meiotic recombination frequencies.Q51046179
Human KVLQT1 gene shows tissue-specific imprinting and encompasses Beckwith-Wiedemann syndrome chromosomal rearrangements.Q52196602
Relaxation of imprinted genes in human cancer.Q52545355
Parental imprinting of the mouse insulin-like growth factor II gene.Q55052428
IGF2 is parentally imprinted during human embryogenesis and in the Beckwith-Wiedemann syndromeQ70765937
Imprinted genes have few and small intronsQ70972792
Parental genomic imprinting of the human IGF2 geneQ72222239
Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumourQ72703028
Epigenetic lesions at the H19 locus in Wilms' tumour patientsQ72703033
Parental imprinting of the mouse H19 geneQ22122365
Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmiasQ24311437
A novel L23-related gene 40 kb downstream of the imprinted H19 gene is biallelically expressed in mid-fetal and adult human tissuesQ24314602
Monoallelic expression of the human H19 geneQ28184725
Genomic imprinting in mammalian development: a parental tug-of-warQ28278146
Disruption of imprinting caused by deletion of the H19 gene region in miceQ28287765
A novel human homologue of yeast nucleosome assembly protein, 65 kb centromeric to the p57KIP2 gene, is biallelically expressed in fetal and adult tissuesQ28297029
Inherited microdeletions in the Angelman and Prader-Willi syndromes define an imprinting centre on human chromosome 15.Q34314269
The human Achaete-Scute homologue 2 (ASCL2,HASH2) maps to chromosome 11p15.5, close to IGF2 and is expressed in extravillus trophoblasts.Q34428055
Epigenetic changes encompassing the IGF2/H19 locus associated with relaxation of IGF2 imprinting and silencing of H19 in Wilms tumorQ34572727
DNA methylation: evolution of a bacterial immune function into a regulator of gene expression and genome structure in higher eukaryotesQ37581127
Sex, maps, and imprintingQ37623659
Genomic imprinting of p57KIP2, a cyclin-dependent kinase inhibitor, in mouseQ38291049
Genomic imprinting of Mash2, a mouse gene required for trophoblast developmentQ38298288
Polymorphisms in the human apolipoprotein-J/clusterin gene: ethnic variation and distribution in Alzheimer's diseaseQ38352857
Parental imprinting of autosomal mammalian genesQ40672445
Creation of genomic methylation patternsQ40986760
Chromosome 11p15.5 regional imprinting: comparative analysis of KIP2 and H19 in human tissues and Wilms' tumorsQ41178952
Allele-specific replication timing of imprinted gene regionsQ41541045
An extended region of biallelic gene expression and rodent-human synteny downstream of the imprinted H19 gene on chromosome 11p15.5.Q42646441
Parental imprinting of the Mas protooncogene in mouseQ46725382
Identification of Grf1 on mouse chromosome 9 as an imprinted gene by RLGS-M.Q48060772
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectapoptotic processQ14599311
Pleckstrin homology like domain family A member 2Q21122517
P304page(s)2021-2029
P577publication date1997-11-01
P1433published inHuman Molecular GeneticsQ2720965
P1476titleThe IPL gene on chromosome 11p15.5 is imprinted in humans and mice and is similar to TDAG51, implicated in Fas expression and apoptosis
P478volume6

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cites work (P2860)
Q22009166A novel imprinted gene, encoding a RING zinc-finger protein, and overlapping antisense transcript in the Prader-Willi syndrome critical region
Q35096694An extended domain of Kcnq1ot1 silencing revealed by an imprinted fluorescent reporter
Q31147226Antisense transcripts with FANTOM2 clone set and their implications for gene regulation
Q38089794Beckwith-Wiedemann and Silver-Russell syndromes: opposite developmental imbalances in imprinted regulators of placental function and embryonic growth
Q40462752Biallelic expression of Tssc4, Nap1l4, Phlda2 and Osbpl5 in adult cattle.
Q47818769C11orf21, a novel gene within the Beckwith-Wiedemann syndrome region in human chromosome 11p15.5.
Q33285306Cdkn1c (p57Kip2) is the major regulator of embryonic growth within its imprinted domain on mouse distal chromosome 7.
Q33997704Characterisation of marsupial PHLDA2 reveals eutherian specific acquisition of imprinting
Q24647126Characterization of conserved and nonconserved imprinted genes in swine
Q35077074Chromosome-wide analysis of parental allele-specific chromatin and DNA methylation.
Q34241318Death the Fas way: regulation and pathophysiology of CD95 and its ligand
Q33889437Developmental stage-specific imprinting of IPL in domestic pigs (Sus scrofa).
Q42658164Disruption of an imprinted gene cluster by a targeted chromosomal translocation in mice
Q35806688Domain regulation of imprinting cluster in Kip2/Lit1 subdomain on mouse chromosome 7F4/F5: large-scale DNA methylation analysis reveals that DMR-Lit1 is a putative imprinting control region
Q36421376Epigenetic and phenotypic consequences of a truncation disrupting the imprinted domain on distal mouse chromosome 7.
Q34734556Epigenetic regulation of placental endocrine lineages and complications of pregnancy
Q36499262Expression of KCNQ1OT1, CDKN1C, H19, and PLAGL1 and the methylation patterns at the KvDMR1 and H19/IGF2 imprinting control regions is conserved between human and bovine
Q28505485Fetal overgrowth in the Cdkn1c mouse model of Beckwith-Wiedemann syndrome
Q36976941Gain of imprinting at chromosome 11p15: A pathogenetic mechanism identified in human hepatocarcinomas
Q28289659Genes affecting the cell cycle, growth, maintenance, and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling
Q33875930Genetics of Beckwith-Wiedemann syndrome-associated tumors: common genetic pathways
Q39573980Genome-wide assessment of imprinted expression in human cells
Q77809556Genomic imprinting and cancer
Q33721384Genomic imprinting and chromatin insulation in Beckwith-Wiedemann syndrome
Q35037387Genomic imprinting: could the chromatin structure be the driving force?
Q33541538Genomic imprinting: implications for human disease
Q35814612High concentrations of long interspersed nuclear element sequence distinguish monoallelically expressed genes
Q74133538Hot-stop PCR: a simple and general assay for linear quantitation of allele ratios
Q42661390Hypoxia influences expression profile of Pleckstrin homology-like domain, family A, member 2 in Indian catfish, Clarias batrachus (Linnaeus, 1758): a new candidate gene for hypoxia tolerance in fish
Q39741184Identification of Hodgkin and Reed-Sternberg cell-specific genes by gene expression profiling
Q51803860Identification of a putative transcriptome signature common to neuroblastoma and neural crest cells.
Q37543706Imprinting and extraembryonic tissues-mom takes control
Q24291248Inhibition of protein synthesis by the T cell receptor-inducible human TDAG51 gene product
Q41759014Insulin-like growth factor 2 and overgrowth: molecular biology and clinical implications
Q34241144Isolating the role of elevated Phlda2 in asymmetric late fetal growth restriction in mice
Q35943539Lentivirus-mediated PHLDA2 overexpression inhibits trophoblast proliferation, migration and invasion, and induces apoptosis
Q24684284Loss of imprinting of a paternally expressed transcript, with antisense orientation to KVLQT1, occurs frequently in Beckwith-Wiedemann syndrome and is independent of insulin-like growth factor II imprinting
Q56889416Maternal care boosted by paternal imprinting in mammals
Q35877833Maternal inheritance of a promoter variant in the imprinted PHLDA2 gene significantly increases birth weight
Q33774256Multiple mechanisms regulate imprinting of the mouse distal chromosome 7 gene cluster
Q37445958New Perspectives on Genomic Imprinting, an Essential and Multifaceted Mode of Epigenetic Control in the Developing and Adult Brain
Q52624229PHLDA2 is an imprinted gene in cattle.
Q36648088Paternal deletion of the 11p15.5 centromeric-imprinting control region is associated with alteration of imprinted gene expression and recurrent severe intrauterine growth restriction
Q37484070Paternally expressed, imprinted insulin-like growth factor-2 in chorionic villi correlates significantly with birth weight
Q33692490Phosphatidylinositol 3 kinase modulation of trophoblast cell differentiation
Q28206637Phosphoinositide binding by the pleckstrin homology domains of Ipl and Tih1
Q24530568Placental overgrowth in mice lacking the imprinted gene Ipl
Q39709920Quantitative proteomics analysis reveals molecular networks regulated by epidermal growth factor receptor level in head and neck cancer.
Q28589840Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1
Q34303375Regulation of T-cell death-associated gene 51 (TDAG51) expression in human T-cells.
Q36852705Relationship between placental expression of the imprinted PHLDA2 gene, intrauterine skeletal growth and childhood bone mass
Q33575632Rescue of placental phenotype in a mechanistic model of Beckwith-Wiedemann syndrome
Q36748462Structure and sequence of the human fast skeletal troponin T (TNNT3) gene: insight into the evolution of the gene and the origin of the developmentally regulated isoforms.
Q48000452Syntenic organization of the mouse distal chromosome 7 imprinting cluster and the Beckwith-Wiedemann syndrome region in chromosome 11p15.5.
Q24746223TDAG51 is not essential for Fas/CD95 regulation and apoptosis in vivo
Q45130742TIMP1 and SERPIN-A overexpression and TFF3 and CRABP1 underexpression as biomarkers for papillary thyroid carcinoma.
Q39345500TSSC3 overexpression reduces stemness and induces apoptosis of osteosarcoma tumor-initiating cells
Q38848685The expression of the imprinted gene pleckstrin homology-like domain family A member 2 in placental tissues of preeclampsia and its effects on the proliferation, migration and invasion of trophoblast cells JEG-3.
Q29617273The history of cancer epigenetics
Q28593841The imprinted Phlda2 gene modulates a major endocrine compartment of the placenta to regulate placental demands for maternal resources
Q28512597The imprinted Phlda2 gene regulates extraembryonic energy stores
Q36466639The maternally expressed gene Tssc3 regulates the expression of MASH2 transcription factor in mouse trophoblast stem cells through the AKT-Sp1 signaling pathway
Q27007861The origin and evolution of genomic imprinting and viviparity in mammals
Q37284688The placental imprintome and imprinted gene function in the trophoblast glycogen cell lineage
Q81512924Thioredoxin-interacting protein (txnip) is a glucocorticoid-regulated primary response gene involved in mediating glucocorticoid-induced apoptosis
Q58789746Transcription factor ASCL2 is required for development of the glycogen trophoblast cell lineage
Q24681580Transcriptional map of 170-kb region at chromosome 11p15.5: identification and mutational analysis of the BWR1A gene reveals the presence of mutations in tumor samples
Q33523184Transcriptomic profiling of bovine IVF embryos revealed candidate genes and pathways involved in early embryonic development
Q36392021Two distinct mechanisms of silencing by the KvDMR1 imprinting control region
Q28138506Two novel genes in the center of the 11p15 imprinted domain escape genomic imprinting

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