Platelet-derived growth factor-BB-mediated glycosaminoglycan synthesis is transduced through Akt

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Platelet-derived growth factor-BB-mediated glycosaminoglycan synthesis is transduced through Akt is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1042/BJ3630019
P8608Fatcat IDrelease_vmcrjq7eu5atpiiioql3yqw54e
P932PMC publication ID1222446
P698PubMed publication ID11903042
P5875ResearchGate publication ID11461058

P2093author name stringJinxia Wang
Martin Post
Nicholas J Cartel
P2860cites workAKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomasQ24294176
Further evidence that the inhibition of glycogen synthase kinase-3beta by IGF-1 is mediated by PDK1/PKB-induced phosphorylation of Ser-9 and not by dephosphorylation of Tyr-216Q24309035
Mechanism of activation of protein kinase B by insulin and IGF-1Q24309528
TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor betaQ24310394
AH/PH domain-mediated interaction between Akt molecules and its potential role in Akt regulationQ24317438
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphateQ24317714
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphataseQ24322705
A family of putative tumor suppressors is structurally and functionally conserved in humans and yeastQ24336385
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machineryQ27860586
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase BQ27860731
A putative modular domain present in diverse signaling proteinsQ28269473
Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)Q28297419
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphateQ28301966
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTENQ28513537
Molecular cloning and characterization of a new member of the RAC protein kinase family: association of the pleckstrin homology domain of three types of RAC protein kinase with protein kinase C subspecies and beta gamma subunits of G proteinsQ28569131
PDGF-induced glycosaminoglycan synthesis is mediated via phosphatidylinositol 3-kinaseQ28583835
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase BalphaQ28616168
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinaseQ29618387
Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamilyQ30844287
Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C familiesQ33267524
PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.Q33860504
Nonneuronal expression of Rab3A: induction during adipogenesis and association with different intracellular membranes than Rab3DQ34318760
The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion moleculeQ34620069
A biosynthetic regulated secretory pathway in constitutive secretory cellsQ36237102
Protein kinase C mu is located at the Golgi compartmentQ36822342
Proteoglycans: structures and interactionsQ37285263
Phosphoinositide 3-kinases: a conserved family of signal transducersQ38556727
Rab proteins in regulated exocytosisQ40664339
Akt is a direct target of the phosphatidylinositol 3-kinase. Activation by growth factors, v-src and v-Ha-ras, in Sf9 and mammalian cellsQ41149851
Phosphatidylinositol 3-kinase activity is required at a postendocytic step in platelet-derived growth factor receptor traffickingQ41336419
Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinaseQ41608842
Inositol lipid 5-phosphatases--traffic signals and signal traffic.Q41661205
MAP2 kinase and 70K S6 kinase lie on distinct signalling pathwaysQ41699190
Mechanisms and consequences of activation of protein kinase B/AktQ41751003
Expression of Rab3D N135I inhibits regulated secretion of ACTH in AtT-20 cellsQ42796089
Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.Q42991716
The SH2-like Akt homology (AH) domain of c-akt is present in multiple copies in the genome of vertebrate and invertebrate eucaryotes. Cloning and characterization of the Drosophila melanogaster c-akt homolog Dakt1.Q48085905
A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like regionQ48205638
Spatial and temporal differences in fibroblast behavior in fetal rat lung.Q52234961
The proteins encoded by c-akt and v-akt differ in post-translational modification, subcellular localization and oncogenic potential.Q54654741
p70s6k function is essential for G1 progressionQ59054463
Differential effect of platelet-derived growth factor on glycosaminoglycan synthesis by fetal rat lung cellsQ67567294
Fetal lung epithelial cells express receptors for platelet-derived growth factorQ72850359
The immunosuppressant rapamycin induces inactivation of p70s6k through dephosphorylation of a novel set of sitesQ72865321
Evidence for a symmetrical requirement for Rab5-GTP in in vitro endosome-endosome fusionQ77332986
P433issue1
Pt 1
P407language of work or nameEnglishQ1860
P304page(s)19
19-28
P577publication date2002-04-01
P1433published inBiochemical JournalQ864221
P1476titlePlatelet-derived growth factor-BB-mediated glycosaminoglycan synthesis is transduced through Akt
P478volume363

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cites work (P2860)
Q45091448Abrogation of apoptosis through PDGF-BB-induced sulfated glycosaminoglycan synthesis and secretion
Q54560927TGF-β stimulates biglycan core protein synthesis but not glycosaminoglycan chain elongation via Akt phosphorylation in vascular smooth muscle.

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