| scholarly article | Q13442814 |
| P50 | author | Brian Hemmings | Q4964012 |
| P2093 | author name string | J Park | |
| G L Firestone | |||
| A C Maiyar | |||
| P Buse | |||
| M L Leong | |||
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| 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase | Q24336639 | ||
| A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding | Q25938984 | ||
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| Regulation of protein kinase C zeta by PI 3-kinase and PDK-1 | Q28567633 | ||
| Cell cycle and hormonal control of nuclear-cytoplasmic localization of the serum- and glucocorticoid-inducible protein kinase, Sgk, in mammary tumor cells. A novel convergence point of anti-proliferative and proliferative cell signaling pathways | Q28578871 | ||
| Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha | Q28616168 | ||
| Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B | Q28646376 | ||
| Epithelial sodium channel regulated by aldosterone-induced protein sgk. | Q30650629 | ||
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| Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase | Q36278250 | ||
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| Inefficient homooligomerization contributes to the dependence of myogenin on E2A products for efficient DNA binding | Q38334629 | ||
| Constitutive activation of protein kinase B and phosphorylation of p47phox by a membrane-targeted phosphoinositide 3-kinase | Q41160740 | ||
| p53 stimulates promoter activity of the sgk. serum/glucocorticoid-inducible serine/threonine protein kinase gene in rodent mammary epithelial cells | Q41197877 | ||
| Immediate-early transcriptional regulation and rapid mRNA turnover of a putative serine/threonine protein kinase. | Q41548094 | ||
| Calcium phosphate-mediated gene transfer: a highly efficient transfection system for stably transforming cells with plasmid DNA. | Q44697855 | ||
| Distribution of the messenger RNA for the extracellularly regulated kinases 1, 2 and 3 in rat brain: effects of excitotoxic hippocampal lesions | Q48654288 | ||
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| Differential expression of sgk mRNA, a member of the Ser/Thr protein kinase gene family, in rat brain after CNS injury. | Q52213939 | ||
| Comparison of the specificities of p70 S6 kinase and MAPKAP kinase-1 identifies a relatively specific substrate for p70 S6 kinase: the N-terminal kinase domain of MAPKAP kinase-1 is essential for peptide phosphorylation | Q71584051 | ||
| Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics | Q72772936 | ||
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | glucocorticoid | Q422549 |
| P304 | page(s) | 3024-33 | |
| P577 | publication date | 1999-06-01 | |
| P1433 | published in | The EMBO Journal | Q1278554 |
| P1476 | title | Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway | |
| P478 | volume | 18 |
| Q33237192 | 3-phosphoinositide-dependent protein kinase-1 (PDK1) promotes invasion and activation of matrix metalloproteinases |
| Q28141738 | A 3-phosphoinositide-dependent protein kinase-1 (PDK1) docking site is required for the phosphorylation of protein kinase Czeta (PKCzeta ) and PKC-related kinase 2 by PDK1 |
| Q46983064 | A DAF-16/FoxO3a-dependent longevity signal is initiated by antioxidants |
| Q42461529 | A naturally occurring human Nedd4-2 variant displays impaired ENaC regulation in Xenopus laevis oocytes |
| Q44743329 | A novel defense mechanism that is activated on amyloid-beta insult to mediate cell survival: role of SGK1-STAT1/STAT2 signaling |
| Q93018670 | A novel tumor suppressor protein encoded by circular AKT3 RNA inhibits glioblastoma tumorigenicity by competing with active phosphoinositide-dependent Kinase-1 |
| Q39922852 | A phosphoserine-regulated docking site in the protein kinase RSK2 that recruits and activates PDK1. |
| Q24534951 | A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation |
| Q38134714 | AKT-independent PI3-K signaling in cancer - emerging role for SGK3. |
| Q35050584 | Ablation of SGK1 impairs endothelial cell migration and tube formation leading to decreased neo-angiogenesis following myocardial infarction |
| Q34652990 | Activation of NHE3 by dexamethasone requires phosphorylation of NHE3 at Ser663 by SGK1 |
| Q92740085 | Activation of RSK by phosphomimetic substitution in the activation loop is prevented by structural constraints |
| Q43510705 | Activation of serum- and glucocorticoid-induced protein kinase (Sgk) by cyclic AMP and insulin |
| Q37387798 | Activation of serum/glucocorticoid-induced kinase 1 (SGK1) underlies increased glycogen levels, mTOR activation, and autophagy defects in Lafora disease |
| Q36877807 | Activity of the p110-alpha subunit of phosphatidylinositol-3-kinase is required for activation of epithelial sodium transport |
| Q26851565 | Akt isoforms in vascular disease |
| Q39787858 | Akt regulates basic helix-loop-helix transcription factor-coactivator complex formation and activity during neuronal differentiation |
| Q39460733 | Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells |
| Q38624678 | Aldosterone-stimulated SGK1 activity mediates profibrotic signaling in the mesangium |
| Q35173847 | Aldosterone: its receptor, target genes, and actions |
| Q24669948 | An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis |
| Q46240581 | Association of SGK 1 Gene polymorphisms with type 2 diabetes |
| Q30659210 | BMK1 mediates growth factor-induced cell proliferation through direct cellular activation of serum and glucocorticoid-inducible kinase |
| Q99234018 | Behavioral effects of SGK1 knockout in VTA and dopamine neurons |
| Q37175584 | Blunted IgE-mediated activation of mast cells in mice lacking the serum- and glucocorticoid-inducible kinase SGK3 |
| Q34466975 | Blunted hypertensive effect of combined fructose and high-salt diet in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase SGK1. |
| Q24303630 | COMMD1 downregulates the epithelial sodium channel through Nedd4-2 |
| Q40651121 | Characterization of Insulin Inhibition of Transactivation by a C-terminal Fragment of the Forkhead Transcription Factor Foxo1 in Rat Hepatoma Cells |
| Q22010747 | Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase |
| Q93077812 | Chemogenetic Activation of Prefrontal Cortex in Shank3-Deficient Mice Ameliorates Social Deficits, NMDAR Hypofunction, and Sgk2 Downregulation |
| Q26738964 | Chronic over-nutrition and dysregulation of GSK3 in diseases |
| Q59050007 | Combined 3D QSAR Based Virtual Screening and Molecular Docking Study of Some Selected PDK-1 Kinase Inhibitors |
| Q34777003 | Concerted action of ENaC, Nedd4-2, and Sgk1 in transepithelial Na(+) transport |
| Q35089685 | Concerted roles of SGK1 and the Na+/H+ exchanger regulatory factor 2 (NHERF2) in regulation of NHE3. |
| Q38304968 | Control of cardiac repolarization by phosphoinositide 3-kinase signaling to ion channels |
| Q46421531 | Corticotropin-releasing hormone stimulates SGK-1 kinase expression in cultured hippocampal neurons via CRH-R1. |
| Q27648914 | Crystal structure of the kinase domain of serum and glucocorticoid-regulated kinase 1 in complex with AMP-PNP |
| Q39895269 | DNA-dependent protein kinase-mediated phosphorylation of protein kinase B requires a specific recognition sequence in the C-terminal hydrophobic motif |
| Q35139549 | Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty |
| Q46560760 | Decreased intestinal glucose transport in the sgk3-knockout mouse |
| Q39939547 | Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic. |
| Q39736019 | Dexamethasone and insulin activate serum and glucocorticoid-inducible kinase 1 (SGK1) via different molecular mechanisms in cortical collecting duct cells. |
| Q34666304 | Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR |
| Q40056726 | Differential regulation of serum- and glucocorticoid-inducible kinase 1 (SGK1) splice variants based on alternative initiation of transcription |
| Q44078427 | Differential transcriptional regulation by the alpha- and gamma-catalytic subunit isoforms of cAMP-dependent protein kinase |
| Q40649584 | Differing Roles of Akt and Serum- and Glucocorticoid-regulated Kinase in Glucose Metabolism, DNA Synthesis, and Oncogenic Activity |
| Q40816988 | Disruption of 3-phosphoinositide-dependent kinase 1 (PDK1) signaling by the anti-tumorigenic and anti-proliferative agent n-alpha-tosyl-l-phenylalanyl chloromethyl ketone |
| Q42443342 | Distribution and regulation of expression of serum- and glucocorticoid-induced kinase-1 in the rat kidney |
| Q38364235 | Disturbance of oligodendrocyte function plays a key role in the pathogenesis of schizophrenia and major depressive disorder. |
| Q40096436 | Downregulation of SGK1 by nucleotides in renal tubular epithelial cells |
| Q39130546 | Dynamic change of SGK expression and its role in neuron apoptosis after traumatic brain injury |
| Q41485386 | Dysregulation of epithelial Na+ absorption induced by inhibition of the kinases TORC1 and TORC2. |
| Q37298076 | Effects of Caenorhabditis elegans sgk-1 mutations on lifespan, stress resistance, and DAF-16/FoxO regulation |
| Q41869562 | Effects of mineralocorticoid receptor blockade on glucocorticoid-induced renal injury in adrenalectomized rats |
| Q41665307 | Effects of nominally selective inhibitors of the kinases PI3K, SGK1 and PKB on the insulin-dependent control of epithelial Na+ absorption |
| Q39253544 | Effects of peroxisome proliferator-activated receptor gamma agonists on Na+ transport and activity of the kinase SGK1 in epithelial cells from lung and kidney |
| Q34324055 | Endothelial Na+/H+ exchanger NHE1 participates in redox-sensitive leukocyte recruitment triggered by methylglyoxal |
| Q28576355 | Enrichment enhances the expression of sgk, a glucocorticoid-induced gene, and facilitates spatial learning through glutamate AMPA receptor mediation |
| Q43283870 | Epinephrine-induced hyperpolarization of pancreatic islet cells is sensitive to PI3K-PDK1 signaling |
| Q36159027 | Epithelial Na⁺ channel activity in human airway epithelial cells: the role of serum and glucocorticoid-inducible kinase 1. |
| Q35213503 | Epithelial sodium channel regulation by cell surface-associated serum- and glucocorticoid-regulated kinase 1 |
| Q24685447 | Erythropoietin stimulates phosphorylation and activation of GATA-1 via the PI3-kinase/AKT signaling pathway |
| Q36858524 | Estrogen receptor β regulates endometriotic cell survival through serum and glucocorticoid-regulated kinase activation |
| Q27308641 | Ethanol regulation of serum glucocorticoid kinase 1 expression in DBA2/J mouse prefrontal cortex |
| Q58438131 | Evidence That 3-Phosphoinositide-dependent Protein Kinase-1 Mediates Phosphorylation of p70 S6 Kinasein Vivoat Thr-412 as well as Thr-252 |
| Q39760859 | Evolution of the TOR pathway |
| Q24528133 | Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3 |
| Q42443601 | Expression and distribution of the serum and glucocorticoid regulated kinase and the epithelial sodium channel subunits in the human cornea |
| Q34426269 | Expression and role of serum and glucocorticoid-regulated kinase 2 in the regulation of Na+/H+exchanger 3 in the mammalian kidney |
| Q36838210 | Expression of a novel isoform of Na(+)/H(+) exchanger 3 in the kidney and intestine of banded houndshark, Triakis scyllium |
| Q28565417 | Expression of serum- and glucocorticoid-inducible kinase is regulated in an experience-dependent manner and can cause dendrite growth |
| Q33685686 | Expression of serum- and glucocorticoid-regulated kinase 1 and its association with clinicopathological factors and the survival of patients with adenocarcinoma of the esophagogastric junction |
| Q34165571 | Expression of the serum- and glucocorticoid-inducible protein kinase, Sgk, is a cell survival response to multiple types of environmental stress stimuli in mammary epithelial cells |
| Q37049891 | Forkhead transcription factors and cardiovascular biology |
| Q40410561 | Functional specificity of Sgk1 and Akt1 on ENaC activity |
| Q48708923 | Gene expression in the brain across the sleep-waking cycle |
| Q45145846 | Gene regulation of ENaC subunits by serum- and glucocorticoid-inducible kinase-1. |
| Q28212817 | Glucocorticoid activation of Na(+)/H(+) exchanger isoform 3 revisited. The roles of SGK1 and NHERF2 |
| Q40816743 | Glucocorticoid receptor-mediated protection from apoptosis is associated with induction of the serine/threonine survival kinase gene, sgk-1. |
| Q37389065 | Glucocorticoids can activate the alpha-ENaC gene promoter independently of SGK1. |
| Q40690529 | Hormone-regulated transepithelial Na+ transport in mammalian CCD cells requires SGK1 expression |
| Q36739599 | Hsp90 regulates the phosphorylation and activity of serum- and glucocorticoid-regulated kinase-1. |
| Q42954958 | Hyperaldosteronism and altered expression of an SGK1-dependent sodium transporter in ZDF rats leads to salt dependence of blood pressure |
| Q30876351 | Hyperosmotic stress stimulates promoter activity and regulates cellular utilization of the serum- and glucocorticoid-inducible protein kinase (Sgk) by a p38 MAPK-dependent pathway |
| Q44995332 | Hypotonic activation of volume-sensitive outwardly rectifying chloride channels in cultured PASMCs is modulated by SGK. |
| Q40725936 | Hypotonic induction of SGK1 and Na+ transport in A6 cells |
| Q40197172 | IGF-1 vs insulin: respective roles in modulating sodium transport via the PI-3 kinase/Sgk1 pathway in a cortical collecting duct cell line |
| Q46167735 | IL-1beta-induced cortisol stimulates lung fluid absorption in fetal guinea pigs via SGK-mediated Nedd4-2 inhibition |
| Q40119436 | IL-2 signals through Sgk1 and inhibits proliferation and apoptosis in kidney cancer cells |
| Q34804514 | IL-6 activates serum and glucocorticoid kinase via p38alpha mitogen-activated protein kinase pathway |
| Q24600810 | Identification of a pocket in the PDK1 kinase domain that interacts with PIF and the C-terminal residues of PKA |
| Q40418704 | Identification of calcium-regulated heat-stable protein of 24 kDa (CRHSP24) as a physiological substrate for PKB and RSK using KESTREL. |
| Q40458502 | Identification of different specificity requirements between SGK1 and PKBalpha. |
| Q24528134 | Identification of filamin C as a new physiological substrate of PKBalpha using KESTREL |
| Q28646919 | Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway |
| Q43693180 | Identification of tyrosine phosphorylation sites on 3-phosphoinositide-dependent protein kinase-1 and their role in regulating kinase activity |
| Q40258022 | Impaired intestinal NHE3 activity in the PDK1 hypomorphic mouse |
| Q58437920 | Impaired intestinal and renal glucose transport in PDK-1 hypomorphic mice |
| Q24554299 | Importin-alpha mediates the regulated nuclear targeting of serum- and glucocorticoid-inducible protein kinase (Sgk) by recognition of a nuclear localization signal in the kinase central domain |
| Q39831998 | In vivo role of the PIF-binding docking site of PDK1 defined by knock-in mutation |
| Q35030359 | InAKTivation of insulin/IGF-1 signaling by dephosphorylation |
| Q34182750 | Increased intracellular calcium activates serum and glucocorticoid-inducible kinase 1 (SGK1) through a calmodulin-calcium calmodulin dependent kinase kinase pathway in Chinese hamster ovary cells |
| Q44588830 | Inhibition of PI-3 kinase sensitizes human leukemic cells to histone deacetylase inhibitor-mediated apoptosis through p44/42 MAP kinase inactivation and abrogation of p21(CIP1/WAF1) induction rather than AKT inhibition |
| Q64950400 | Inhibition of SGK1 confers vulnerability to redox dysregulation in cervical cancer. |
| Q28208351 | Inhibition of insulin-induced activation of Akt by a kinase-deficient mutant of the epsilon isozyme of protein kinase C |
| Q64229231 | Insulin ameliorates pulmonary edema through the upregulation of epithelial sodium channel via the PI3K/SGK1 pathway in mice with lipopolysaccharide‑induced lung injury |
| Q42411093 | Insulin regulates adipocyte lipolysis via an Akt-independent signaling pathway |
| Q44170442 | Insulin upregulates the expression of epithelial sodium channel in vitro and in a mouse model of acute lung injury: role of mTORC2/SGK1 pathway |
| Q40803478 | Insulin-stimulated protein kinase B phosphorylation on Ser-473 is independent of its activity and occurs through a staurosporine-insensitive kinase |
| Q30456691 | Intrarenal ghrelin receptors regulate ENaC-dependent sodium reabsorption by a cAMP-dependent pathway |
| Q34184917 | Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy. |
| Q34236816 | Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth |
| Q36334959 | KESTREL: a powerful method for identifying the physiological substrates of protein kinases |
| Q45013882 | Low prevalence of nonconservative mutations of serum and glucocorticoid-regulated kinase (SGK1) gene in hypertensive and renal patients |
| Q37943416 | Mammalian TOR signaling to the AGC kinases |
| Q36445434 | Mechanisms of regulation of epithelial sodium channel by SGK1 in A6 cells |
| Q33819647 | Mineralocorticoid action. |
| Q92726600 | Mitochondrial Permeability Uncouples Elevated Autophagy and Lifespan Extension |
| Q34995907 | Morphine and cocaine increase serum- and glucocorticoid-inducible kinase 1 activity in the ventral tegmental area |
| Q35810566 | Multiple translational isoforms give functional specificity to serum- and glucocorticoid-induced kinase 1. |
| Q40917418 | Ndr protein kinase is regulated by phosphorylation on two conserved sequence motifs |
| Q45171395 | Nedd4-2 phosphorylation induces serum and glucocorticoid-regulated kinase (SGK) ubiquitination and degradation |
| Q42614334 | No-match ORESTES explored as tumor markers |
| Q39968484 | Oncogenic Ras differentially regulates metabolism and anoikis in extracellular matrix-detached cells |
| Q39540837 | Opposite effects of serum- and glucocorticoid-regulated kinase-1 and glucocorticoids on POMC transcription and ACTH release |
| Q27022626 | Organization of the ENaC-regulatory machinery |
| Q39119229 | PDK1 controls upstream PI3K expression and PIP3 generation. |
| Q24297416 | PDK1, the master regulator of AGC kinase signal transduction |
| Q33341346 | PDK2: the missing piece in the receptor tyrosine kinase signaling pathway puzzle |
| Q51116502 | PI3-kinase-dependent electrogenic intestinal transport of glucose and amino acids. |
| Q64083920 | PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene Expression |
| Q39200710 | PI3K signaling in cancer: beyond AKT. |
| Q24304880 | PI3K-dependent phosphorylation of Fbw7 modulates substrate degradation and activity |
| Q51613789 | PI3K/SGK1/GSK3β signaling pathway is involved in inhibition of autophagy in neonatal rat cardiomyocytes exposed to hypoxia/reoxygenation by hydrogen sulfide. |
| Q93159544 | PIK3CA Amplification Associates with Aggressive Phenotype but Not Markers of AKT-MTOR Signaling in Endometrial Carcinoma |
| Q34389540 | PKB/AKT: functional insights from genetic models |
| Q46679218 | PTPN12 promotes resistance to oxidative stress and supports tumorigenesis by regulating FOXO signaling |
| Q34302400 | Pathological role of serum- and glucocorticoid-regulated kinase 1 in adverse ventricular remodeling. |
| Q28182447 | Peroxisomal targeting as a tool for assaying potein-protein interactions in the living cell: cytokine-independent survival kinase (CISK) binds PDK-1 in vivo in a phosphorylation-dependent manner |
| Q40365663 | Phosphatidylinositol 3,4,5-trisphosphate mediates aldosterone stimulation of epithelial sodium channel (ENaC) and interacts with gamma-ENaC. |
| Q46914956 | Phosphoinositide 3-kinase dependent regulation of Kv channels in dendritic cells |
| Q33707626 | Phosphoinositide-dependent phosphorylation of PDK1 regulates nuclear translocation |
| Q33967145 | Phosphopeptide screen uncovers novel phosphorylation sites of Nedd4-2 that potentiate its inhibition of the epithelial Na+ channel |
| Q31100056 | Phosphoprotein analysis using antibodies broadly reactive against phosphorylated motifs |
| Q92147833 | Phosphorylation at distinct subcellular locations underlies specificity in mTORC2-mediated activation of SGK1 and Akt |
| Q24534668 | Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression |
| Q42200194 | Phosphorylation of Rictor at Thr1135 impairs the Rictor/Cullin-1 complex to ubiquitinate SGK1. |
| Q58604019 | Phosphorylation of cardiac voltage-gated sodium channel: potential players with multiple dimensions |
| Q28207530 | Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells |
| Q22254023 | Phosphorylation of protein kinase N by phosphoinositide-dependent protein kinase-1 mediates insulin signals to the actin cytoskeleton |
| Q58169387 | Phosphorylation of ser246residue in integrin‐linked kinase 1 by serum‐ and glucocorticoid‐induced kinase 1 is required to form a protein‐protein complex with 14–3–3 |
| Q33927227 | Plasma corticosterone activates SGK1 and induces morphological changes in oligodendrocytes in corpus callosum |
| Q27346904 | Prohibitin-mediated lifespan and mitochondrial stress implicate SGK-1, insulin/IGF and mTORC2 in C. elegans |
| Q44658837 | Prolongation of insulin-induced activation of mitogen-activated protein kinases ERK 1/2 and phosphatidylinositol 3-kinase by vanadyl sulfate, a protein tyrosine phosphatase inhibitor |
| Q34203135 | Properties and regulation of glutamine transporter SN1 by protein kinases SGK and PKB. |
| Q34675892 | Protein kinase A-alpha directly phosphorylates FoxO1 in vascular endothelial cells to regulate expression of vascular cellular adhesion molecule-1 mRNA. |
| Q35222208 | Protein kinase B/Akt phosphorylation of PDE3A and its role in mammalian oocyte maturation |
| Q51974609 | Protein kinase CK2 impairs spatial memory formation through differential cross talk with PI-3 kinase signaling: activation of Akt and inactivation of SGK1. |
| Q24551018 | Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a) |
| Q74236515 | Putative role of the phosphatidylinositol 3-kinase-Akt signaling pathway in the survival of granulosa cells |
| Q34816365 | Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids. |
| Q40853905 | Rapid upregulation of serum and glucocorticoid-regulated kinase (sgk) gene expression by corticosteroids in vivo |
| Q48398988 | Region-specific transcriptional changes following the three antidepressant treatments electro convulsive therapy, sleep deprivation and fluoxetine |
| Q35261898 | Regression of glomerular and tubulointerstitial injuries by dietary salt reduction with combination therapy of angiotensin II receptor blocker and calcium channel blocker in Dahl salt-sensitive rats |
| Q28205154 | Regulation and physiological roles of serum- and glucocorticoid-induced protein kinase isoforms |
| Q40048813 | Regulation of 3-phosphoinositide-dependent protein kinase-1 (PDK1) by Src involves tyrosine phosphorylation of PDK1 and Src homology 2 domain binding |
| Q46387238 | Regulation of GluR1 abundance in murine hippocampal neurones by serum- and glucocorticoid-inducible kinase 3. |
| Q44811028 | Regulation of Na+ transport by aldosterone: signaling convergence and cross talk between the PI3-K and MAPK1/2 cascades |
| Q36579586 | Regulation of NaCl transport in the renal collecting duct: lessons from cultured cells |
| Q37340702 | Regulation of OSR1 and the sodium, potassium, two chloride cotransporter by convergent signals. |
| Q42472971 | Regulation of basal gastric acid secretion by the glycogen synthase kinase GSK3. |
| Q24669638 | Regulation of cytokine-independent survival kinase (CISK) by the Phox homology domain and phosphoinositides |
| Q42510576 | Regulation of epithelial sodium channel activity through a region of the carboxyl terminus of the alpha -subunit. Evidence for intracellular kinase-mediated reactions |
| Q37005273 | Regulation of gastric acid secretion by PKB/Akt2 |
| Q42480447 | Regulation of gastric acid secretion by the serum and glucocorticoid inducible kinase isoform SGK3. |
| Q44912987 | Regulation of glucose transporter SGLT1 by ubiquitin ligase Nedd4-2 and kinases SGK1, SGK3, and PKB. |
| Q47882867 | Regulation of intestinal phosphate cotransporter NaPi IIb by ubiquitin ligase Nedd4-2 and by serum- and glucocorticoid-dependent kinase 1. |
| Q37067582 | Regulation of psychostimulant-induced signaling and gene expression in the striatum |
| Q48893193 | Regulation of sgk by aldosterone and its effects on the epithelial Na(+) channel |
| Q34760609 | Regulation of the FoxO family of transcription factors by phosphatidylinositol-3 kinase-activated signaling |
| Q38369684 | Regulation of the cardiac Na+ channel NaV1.5 by post-translational modifications. |
| Q35013324 | Regulation of the epithelial sodium channel by accessory proteins |
| Q27007073 | Regulation of αENaC transcription |
| Q50649543 | Renal Ca2+ handling in sgk1 knockout mice. |
| Q36175870 | Renal tubular transport and the genetic basis of hypertensive disease |
| Q37375772 | Rescue of DeltaF508-CFTR by the SGK1/Nedd4-2 signaling pathway |
| Q34125987 | Rictor Forms a Complex with Cullin-1 to Promote SGK1 Ubiquitination and Destruction |
| Q37111299 | Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans |
| Q42523497 | Role of PKC isoforms in glucose transport in 3T3-L1 adipocytes: insignificance of atypical PKC. |
| Q44185240 | Role of SGK in hormonal regulation of epithelial sodium channel in A6 cells |
| Q42654050 | Role of SGK1 in nitric oxide inhibition of ENaC in Na+-transporting epithelia |
| Q35980264 | Role of Sgk1 in salt and potassium homeostasis. |
| Q35206813 | Role of serum- and glucocorticoid-inducible kinase-1 in regulating torsion-induced apoptosis in rats |
| Q40264478 | Role of the Phox homology domain and phosphorylation in activation of serum and glucocorticoid-regulated kinase-3. |
| Q42515487 | Role of the serum and glucocorticoid inducible kinase SGK1 in glucocorticoid stimulation of gastric acid secretion. |
| Q54977590 | SGK1 Inhibits Autophagy in Murine Muscle Tissue. |
| Q39940605 | SGK1 activity in Na+ absorbing airway epithelial cells monitored by assaying NDRG1-Thr346/356/366 phosphorylation. |
| Q46456467 | SGK1 dependence of insulin induced hypokalemia |
| Q44723659 | SGK1 increases Na,K-ATP cell-surface expression and function in Xenopus laevis oocytes. |
| Q35651474 | SGK1 inhibits cellular apoptosis and promotes proliferation via the MEK/ERK/p53 pathway in colitis |
| Q37182195 | SGK1 is modulated by resistin in vascular smooth muscle cells and in the aorta following diet-induced obesity |
| Q28582941 | SGK1 phosphorylation of IkappaB Kinase alpha and p300 Up-regulates NF-kappaB activity and increases N-Methyl-D-aspartate receptor NR2A and NR2B expression |
| Q45243196 | SGK1, a potential regulator of c-fms related breast cancer aggressiveness |
| Q37680918 | SGK1-sensitive renal tubular glucose reabsorption in diabetes. |
| Q30399129 | SGK1: The Dark Side of PI3K Signaling |
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| Q34496137 | Serine/threonine protein kinase SGK1 in glucocorticoid-dependent transdifferentiation of pancreatic acinar cells to hepatocytes. |
| Q40974306 | Serum Glucocorticoid-Regulated Kinase 1 Blocks CKD-Induced Muscle Wasting Via Inactivation of FoxO3a and Smad2/3. |
| Q43010069 | Serum and glucocorticoid-inducible kinase 1 (SGK1) is necessary for vascular remodeling during angiogenesis |
| Q37477760 | Serum and glucocorticoid-regulated kinase 1 (SGK1) activation in breast cancer: requirement for mTORC1 activity associates with ER-alpha expression |
| Q34623277 | Serum and glucocorticoid-regulated kinase 1 promotes vascular smooth muscle cell proliferation via regulation of β-catenin dynamics |
| Q30571493 | Serum and glucocorticoid-regulated kinase 1 regulates neutrophil clearance during inflammation resolution. |
| Q98733563 | Serum- and glucocorticoid- inducible kinase 2, SGK2, is a novel autophagy regulator and modulates platinum drugs response in cancer cells |
| Q34576663 | Serum- and glucocorticoid-dependent kinase, cell volume, and the regulation of epithelial transport. |
| Q35340637 | Serum- and glucocorticoid-induced kinase 3 in recycling endosomes mediates acute activation of Na+/H+ exchanger NHE3 by glucocorticoids |
| Q37289311 | Serum- and glucocorticoid-induced protein kinase 1 (SGK1) is regulated by store-operated Ca2+ entry and mediates cytoprotection against necrotic cell death |
| Q28578841 | Serum- and glucocorticoid-inducible kinase 1 (SGK1) increases neurite formation through microtubule depolymerization by SGK1 and by SGK1 phosphorylation of tau |
| Q90313205 | Serum- and glucocorticoid-inducible kinase 1 activity reduces dendritic spines in dorsal hippocampus |
| Q92932383 | Serum- and glucocorticoid-inducible kinase 1 and the response to cell stress |
| Q40034016 | Serum- and glucocorticoid-inducible kinase 1 enhances zif268 expression through the mediation of SRF and CREB1 associated with spatial memory formation. |
| Q37950886 | Serum- and glucocorticoid-inducible kinase 1 in the regulation of renal and extrarenal potassium transport |
| Q34515800 | Serum- and glucocorticoid-inducible kinase SGK phosphorylates and negatively regulates B-Raf |
| Q37019203 | Serum- and glucocorticoid-inducible kinase sgk2 stimulates the transport activity of human organic anion transporters 1 by enhancing the stability of the transporter |
| Q41842574 | Serum- and glucocorticoid-regulated kinase 1 is upregulated following unilateral ureteral obstruction causing epithelial-mesenchymal transition |
| Q33292348 | Serum/glucocorticoid-inducible kinase can phosphorylate the cyclic AMP response element binding protein, CREB. |
| Q39561471 | Serum/glucocorticoid-regulated kinase 1 (SGK1) is a prominent target gene of the transcriptional response to cytokines in multiple myeloma and supports the growth of myeloma cells. |
| Q54331309 | Sgk1 sensitivity of Na(+)/H(+) exchanger activity and cardiac remodeling following pressure overload. |
| Q34831355 | Signalling, cell cycle and pluripotency in embryonic stem cells |
| Q38282527 | Sodium chloride, SGK1, and Th17 activation |
| Q47655027 | Stimulation of the epithelial sodium channel (ENaC) by the serum- and glucocorticoid-inducible kinase (Sgk) involves the PY motifs of the channel but is independent of sodium feedback inhibition |
| Q38895048 | Strong association of serum- and glucocorticoid-regulated kinase 1 with peripheral and adipose tissue inflammation in obesity |
| Q47651331 | Structural basis of membrane targeting by the Phox homology domain of cytokine-independent survival kinase (CISK-PX). |
| Q40187398 | Subcellular location of serum- and glucocorticoid-induced kinase-1 in renal and mammary epithelial cells |
| Q36530922 | Sustained postexercise increases in AS160 Thr642 and Ser588 phosphorylation in skeletal muscle without sustained increases in kinase phosphorylation |
| Q38113583 | Targeting phosphatidylinositol 3-kinase signaling in acute myelogenous leukemia |
| Q40819524 | The ERK MAP kinase pathway mediates induction of SGK (serum- and glucocorticoid-inducible kinase) by growth factors |
| Q40267610 | The N-terminus of the serum- and glucocorticoid-inducible kinase Sgk1 specifies mitochondrial localization and rapid turnover |
| Q34155123 | The Na(+)/H(+) exchanger regulatory factor 2 mediates phosphorylation of serum- and glucocorticoid-induced protein kinase 1 by 3-phosphoinositide-dependent protein kinase 1. |
| Q24531972 | The PI3K-PDK1 connection: more than just a road to PKB |
| Q28345841 | The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB. |
| Q91962615 | The Upstream Pathway of mTOR-Mediated Autophagy in Liver Diseases |
| Q38370773 | The activity of the androgen receptor variant AR-V7 is regulated by FOXO1 in a PTEN-PI3K-AKT-dependent way. |
| Q60921637 | The chemical diversity and structure-based discovery of allosteric modulators for the PIF-pocket of protein kinase PDK1 |
| Q34116818 | The complexes of mammalian target of rapamycin. |
| Q27937052 | The conserved Pkh-Ypk kinase cascade is required for endocytosis in yeast |
| Q27022601 | The epithelial sodium channel δ-subunit: new notes for an old song |
| Q47804413 | The mTOR kinase inhibitor everolimus synergistically enhances the anti-tumor effect of the Bruton's tyrosine kinase (BTK) inhibitor PLS-123 on Mantle cell lymphoma |
| Q39680087 | The neuronal-specific SGK1.1 kinase regulates {delta}-epithelial Na+ channel independently of PY motifs and couples it to phospholipase C signaling |
| Q29547860 | The phosphatidylinositol 3-Kinase AKT pathway in human cancer |
| Q43884355 | The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria |
| Q37200384 | The phosphatidylinositol 3-kinases (PI3K) inhibitor GS-1101 synergistically potentiates histone deacetylase inhibitor-induced proliferation inhibition and apoptosis through the inactivation of PI3K and extracellular signal-regulated kinase pathways. |
| Q37454384 | The phosphoinositide 3-kinase pathway in human cancer: genetic alterations and therapeutic implications. |
| Q57272881 | The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells |
| Q34365414 | The role of SGK1 in hormone-regulated sodium transport |
| Q27007093 | The role of the ENaC-regulatory complex in aldosterone-mediated sodium transport |
| Q24297640 | The serine/threonine kinases SGK2 and SGK3 are potent stimulators of the epithelial Na+ channel alpha,beta,gamma-ENaC |
| Q36934467 | The serum- and glucocorticoid-induced protein kinase-1 (Sgk-1) mitochondria connection: identification of the IF-1 inhibitor of the F(1)F(0)-ATPase as a mitochondria-specific binding target and the stress-induced mitochondrial localization of endoge |
| Q36174649 | The stimulus-dependent co-localization of serum- and glucocorticoid-regulated protein kinase (Sgk) and Erk/MAPK in mammary tumor cells involves the mutual interaction with the importin-alpha nuclear import protein |
| Q38042938 | Therapeutic targeting of the phosphatidylinositol 3-kinase signaling pathway: novel targeted therapies and advances in the treatment of colorectal cancer |
| Q45091970 | Tissue-specific expression of the transcriptionally regulated serum and glucocorticoid-inducible protein kinase (Sgk) during mouse embryogenesis |
| Q33949444 | Two splice variants of protein kinase B gamma have different regulatory capacity depending on the presence or absence of the regulatory phosphorylation site serine 472 in the carboxyl-terminal hydrophobic domain |
| Q28221408 | Ubiquitin modification of serum and glucocorticoid-induced protein kinase-1 (SGK-1) |
| Q39660079 | Ubiquitin-proteasome degradation of serum- and glucocorticoid-regulated kinase-1 (SGK-1) is mediated by the chaperone-dependent E3 ligase CHIP |
| Q34694707 | Ultrasensitive and absolute quantification of the phosphoinositide 3-kinase/Akt signal transduction pathway by mass spectrometry |
| Q50641642 | Upregulation of HERG channels by the serum and glucocorticoid inducible kinase isoform SGK3. |
| Q33900653 | WNK1 activates SGK1 to regulate the epithelial sodium channel. |
| Q27934191 | Yeast protein kinases and the RHO1 exchange factor TUS1 are novel components of the cell integrity pathway in yeast |
| Q35182926 | mSIN1 protein mediates SGK1 protein interaction with mTORC2 protein complex and is required for selective activation of the epithelial sodium channel |
| Q24324148 | mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1) |
| Q33834293 | mTOR complex-2 activates ENaC by phosphorylating SGK1. |
| Q35242354 | mTORC2 regulates renal tubule sodium uptake by promoting ENaC activity |
| Q28583307 | sgk, a primary glucocorticoid-induced gene, facilitates memory consolidation of spatial learning in rats |
| Q40752362 | sgk: an essential convergence point for peptide and steroid hormone regulation of ENaC-mediated Na+ transport |
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