IEX-1: a new ERK substrate involved in both ERK survival activity and ERK activation

scientific article

IEX-1: a new ERK substrate involved in both ERK survival activity and ERK activation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/EMBOJ/CDF488
P3181OpenCitations bibliographic resource ID2869107
P932PMC publication ID129026
P698PubMed publication ID12356731
P5875ResearchGate publication ID11100268

P2093author name stringClaire Letourneux
Françoise Porteu
Josefina Garcia
Yunbin Ye
Guillaume Pezeron
Valérie Arranz
P2860cites workInteraction of mitogen-activated protein kinases with the kinase interaction motif of the tyrosine phosphatase PTP-SL provides substrate specificity and retains ERK2 in the cytoplasmQ22010423
JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathwayQ22010669
Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK-dependent phosphorylationQ22011000
Cloning and characterization of a family of proteins associated with MplQ24292135
Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranesQ24317668
MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substratesQ24322852
IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survivalQ24323200
Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic miceQ24530757
Survival function of ERK1/2 as IL-3-activated, staurosporine-resistant Bcl2 kinasesQ37109460
The proliferation-associated early response gene p22/PRG1 is a novel p53 target geneQ38336616
Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: molecular characterization of the involved signaling pathway.Q39451489
Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entryQ40976467
Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinaseQ41115678
Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factorQ41978360
Genomic structure, cDNA sequence, and expression of gly96, a growth factor-inducible immediate-early gene encoding a short-lived glycosylated proteinQ42811388
Desensitization of Ras Activation by a Feedback Disassociation of the SOS-Grb2 ComplexQ42824495
Expression of the NF-kappa B target gene IEX-1 (p22/PRG1) does not prevent cell death but instead triggers apoptosis in Hela cellsQ43539821
Inhibition of JNK activation through NF-kappaB target genesQ43802523
Respiratory syncytial virus infection induces expression of the anti-apoptosis gene IEX-1L in human respiratory epithelial cells.Q44750390
A MAP kinase docking site is required for phosphorylation and activation of p90(rsk)/MAPKAP kinase-1.Q48922580
Catalytic Activation of the Phosphatase MKP-3 by ERK2 Mitogen-Activated Protein KinaseQ60164205
Mullerian inhibiting substance inhibits breast cancer cell growth through an NFkappa B-mediated pathwayQ73939153
PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif.Q24533479
Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1Q24617367
Activation mechanism of the MAP kinase ERK2 by dual phosphorylationQ27743261
Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activationQ28131755
Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanismsQ28137802
Activation of NF-kappa B by XIAP, the X chromosome-linked inhibitor of apoptosis, in endothelial cells involves TAK1Q28144306
Mammalian MAP kinase signalling cascadesQ28204140
Distinct binding determinants for ERK2/p38alpha and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1Q28208304
Mechanism of desensitization of the epidermal growth factor receptor protein-tyrosine kinaseQ28208617
An immediate response of ribosomal transcription to growth factor stimulation in mammals is mediated by ERK phosphorylation of UBFQ28210345
Identification of an extracellular signal-regulated kinase (ERK) docking site in ribosomal S6 kinase, a sequence critical for activation by ERK in vivoQ28294928
IEX-1, an immediate early gene, increases the rate of apoptosis in keratinocytesQ28508741
Regulation of carbamoyl phosphate synthetase by MAP kinaseQ28578262
Reconstitution of mitogen-activated protein kinase phosphorylation cascades in bacteria. Efficient synthesis of active protein kinasesQ28579710
Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localizationQ28609061
Growth factor-stimulated MAP kinase induces rapid retrophosphorylation and inhibition of MAP kinase kinase (MEK1)Q28609139
Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2Q28609906
Identification of novel MAP kinase pathway signaling targets by functional proteomics and mass spectrometryQ28679059
Regulation of transcription by MAP kinase cascadesQ29618477
A conserved docking motif in MAP kinases common to substrates, activators and regulatorsQ29619999
The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domainQ29620270
Mitogen-activated protein kinases: specific messages from ubiquitous messengersQ30303652
Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II.Q30460881
The Elk-1 ETS-domain transcription factor contains a mitogen-activated protein kinase targeting motif.Q33770637
NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1.Q33959017
Thrombopoietin-mediated sustained activation of extracellular signal-regulated kinase in UT7-Mpl cells requires both Ras-Raf-1- and Rap1-B-Raf-dependent pathwaysQ33967880
Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signalsQ34336994
Identification and characterization of a radiation-inducible glycosylated human early-response gene.Q34375596
PRG1: a novel early-response gene transcriptionally induced by pituitary adenylate cyclase activating polypeptide in a pancreatic carcinoma cell lineQ34382916
A novel immediate early response gene, IEX-1, is induced by ultraviolet radiation in human keratinocytesQ34486211
Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinaseQ35186927
Phosphorylation and association with the transcription factor Atf1 regulate localization of Spc1/Sty1 stress-activated kinase in fission yeast.Q35200411
Growth factor-induced p42/p44 MAPK nuclear translocation and retention requires both MAPK activation and neosynthesis of nuclear anchoring proteinsQ36288233
Control of thrombopoietin-induced megakaryocytic differentiation by the mitogen-activated protein kinase pathwayQ36571164
P433issue19
P407language of work or nameEnglishQ1860
P304page(s)5151-63
P577publication date2002-10-01
P1433published inThe EMBO JournalQ1278554
P1476titleIEX-1: a new ERK substrate involved in both ERK survival activity and ERK activation
P478volume21

Reverse relations

cites work (P2860)
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