Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer

scientific article

Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1158/2159-8290.CD-12-0558
P3181OpenCitations bibliographic resource ID254072
P932PMC publication ID4078408
P698PubMed publication ID23729478

P50authorVictor VelculescuQ7926425
Francesco GalimiQ84074916
Giorgia MigliardiQ84074917
Livio TrusolinoQ88370775
Sebastijan HoborQ114382104
Mark SausenQ116781886
Andrea CassingenaQ117234514
Marcello GambacortaQ117804625
Calogero LauricellaQ117805144
Elisa ScalaQ117805150
Davide ZecchinQ117805151
Federica Di NicolantonioQ28321686
Alberto BardelliQ28321691
Andrea Sartore-BianchiQ28321693
Salvatore SienaQ28321703
Paolo M. ComoglioQ37381902
Andrea BertottiQ37831180
Silvio Marco VeroneseQ39051644
Luis Alberto Diaz JrQ52152141
Giulia SiravegnaQ56862949
Simona CorsoQ56872439
Silvia GiordanoQ56872444
Emanuele ValtortaQ57018578
Giorgio CortiQ58376404
A AmatuQ82728305
P2093author name stringTimothy Perera
Carlo Zanon
Maria Apicella
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PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximabQ38584695
Inhibition of MEK and PI3K/mTOR suppresses tumor growth but does not cause tumor regression in patient-derived xenografts of RAS-mutant colorectal carcinomasQ39384830
Nuclear EGFR contributes to acquired resistance to cetuximabQ39812008
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Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-METQ41152225
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Mutant Met-mediated transformation is ligand-dependent and can be inhibited by HGF antagonistsQ42810535
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Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort studyQ46465639
Randomized phase II trial of the clinical and biological effects of two dose levels of gefitinib in patients with recurrent colorectal adenocarcinomaQ46856639
A colon cancer cell line (LIM1215) derived from a patient with inherited nonpolyposis colorectal cancer.Q52832708
Is there a role for IGF1R and c-MET pathways in resistance to cetuximab in metastatic colorectal cancer?Q54361260
Genetic and Expression Analysis of MET, MACC1, and HGF in Metastatic Colorectal Cancer: Response to Met Inhibition in Patient Xenografts and Pathologic CorrelationsQ56688160
c-Met autocrine activation induces development of malignant melanoma and acquisition of the metastatic phenotypeQ77583076
Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistance escaping treatment by the anti-EGFR monoclonal antibody cetuximabQ81098062
Genetic heterogeneity and cancer drug resistanceQ83791245
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectcolorectal cancerQ188874
colorectal carcinomaQ25493920
P304page(s)658-673
P577publication date2013-06-02
P1433published inCancer DiscoveryQ15724440
P1476titleAmplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer
P478volume3

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