review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Deric L Wheeler | |
Emily F Dunn | |||
Mari Iida | |||
P2860 | cites work | Cloning of FRK, a novel human intracellular SRC-like tyrosine kinase-encoding gene | Q24305125 |
Rak, a novel nuclear tyrosine kinase expressed in epithelial cells | Q24311867 | ||
Src phosphorylation of the epidermal growth factor receptor at novel sites mediates receptor interaction with Src and P85 alpha | Q24328857 | ||
Activation of the pp60c-src protein kinase is an early event in colonic carcinogenesis | Q24559903 | ||
Increased pp60c-src tyrosyl kinase activity in human neuroblastomas is associated with amino-terminal tyrosine phosphorylation of the src gene product | Q24611377 | ||
Increase in activity and level of pp60c-src in progressive stages of human colorectal cancer | Q24618378 | ||
pp60c-src activation in human colon carcinoma | Q24623701 | ||
Tyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer | Q24803054 | ||
Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants | Q24810573 | ||
PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. | Q27824819 | ||
Focal adhesion kinase enhances signaling through the Shc/extracellular signal-regulated kinase pathway in anaplastic astrocytoma tumor biopsy samples | Q28216057 | ||
Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways | Q28274882 | ||
Lack of mutation at codon 531 of SRC in advanced colorectal cancers from Italian patients | Q28346761 | ||
c-Src-null mice exhibit defects in normal mammary gland development and ERalpha signaling | Q28504741 | ||
Modular binding domains in signal transduction proteins | Q29617351 | ||
Regulation, substrates and functions of src | Q30014830 | ||
Src protein-tyrosine kinase structure and regulation | Q30160814 | ||
Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation | Q30164947 | ||
iyk, a novel intracellular protein tyrosine kinase differentially expressed in the mouse mammary gland and intestine | Q30193510 | ||
STAT5b, a Mediator of Synergism between c-Src and the Epidermal Growth Factor Receptor | Q30310214 | ||
c-Src and cooperating partners in human cancer | Q30434520 | ||
Src family kinases, key regulators of signal transduction | Q30434839 | ||
Mechanism of biological synergy between cellular Src and epidermal growth factor receptor | Q30454480 | ||
Characterization of human epidermal growth factor receptor and c-Src interactions in human breast tumor cells | Q30472067 | ||
A phase I study of erlotinib in combination with gemcitabine and radiation in locally advanced, non-operable pancreatic adenocarcinoma | Q33376728 | ||
Activation of Src kinase in primary colorectal carcinoma: an indicator of poor clinical prognosis | Q34119101 | ||
Elevated c-Src tyrosine kinase activity in premalignant epithelia of ulcerative colitis | Q34124381 | ||
Characterization of protein tyrosine kinases from human breast cancer: involvement of the c-src oncogene product. | Q34250172 | ||
Cloning of BSK, a murine FRK homologue with a specific pattern of tissue distribution. | Q34317180 | ||
Tyr527 is phosphorylated in pp60c-src: implications for regulation | Q34383180 | ||
c-Src protein expression is increased in human breast cancer. An immunohistochemical and biochemical analysis | Q34414942 | ||
A protein tyrosine kinase involved in regulation of pp60c-src function | Q34419128 | ||
Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells | Q34460378 | ||
Activating SRC mutation in a subset of advanced human colon cancers | Q34492512 | ||
Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src | Q34580219 | ||
Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy | Q34674928 | ||
Alterations in the level of phosphotyrosine signal transduction constituents in human parotid tumors | Q71084428 | ||
Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice | Q71606712 | ||
Focal adhesion kinase in the brain: novel subcellular localization and specific regulation by Fyn tyrosine kinase in mutant mice | Q71706890 | ||
No evidence of correlation between mutation at codon 531 of src and the risk of colon cancer in Chinese | Q73515410 | ||
Lack of activating c-SRC mutations at codon 531 in rectal cancer | Q74223535 | ||
Overexpression and activation of the tyrosine kinase Src in human pancreatic carcinoma | Q74237835 | ||
Overexpression of c-Src in areas of hyperproliferation in head and neck cancer, premalignant lesions and benign mucosal disorders | Q74489505 | ||
STAT3 activation abrogates growth factor dependence and contributes to head and neck squamous cell carcinoma tumor growth in vivo | Q74649686 | ||
Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistance escaping treatment by the anti-EGFR monoclonal antibody cetuximab | Q81098062 | ||
Epidermal growth factor receptor expression, signal pathway, and inhibitors in non-small cell lung cancer | Q34992253 | ||
Nonreceptor Protein Tyrosine Kinases Associated with Neuronal Development | Q35212606 | ||
Antiangiogenic and antitumor effects of SRC inhibition in ovarian carcinoma | Q35456086 | ||
Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo | Q35676433 | ||
Receptor mechanisms of rapid extranuclear signalling initiated by steroid hormones | Q35830320 | ||
The SRC-induced mesenchymal state in late-stage colon cancer cells | Q36155027 | ||
A transmissible avian neoplasm. (Sarcoma of the common fowl) by Peyton Rous, M.D., Experimental Medicine for Sept. 1, 1910, vol. 12, pp.696-705 | Q36342899 | ||
Treatment for advanced tumors: SRC reclaims center stage | Q36420034 | ||
Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity | Q36644521 | ||
The Src signaling pathway: a potential target in melanoma and other malignancies | Q36675509 | ||
CEACAM6 is a determinant of pancreatic adenocarcinoma cellular invasiveness | Q36695688 | ||
Src, chemoresistance and epithelial to mesenchymal transition: are they related? | Q36757204 | ||
Preclinical evaluation of dasatinib, a potent Src kinase inhibitor, in melanoma cell lines | Q36940730 | ||
Inhibition of Src family kinases with dasatinib blocks migration and invasion of human melanoma cells | Q37401245 | ||
src expression in small-cell lung carcinoma and other neuroendocrine malignancies | Q37900034 | ||
Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells | Q38353138 | ||
Src kinases mediate STAT growth pathways in squamous cell carcinoma of the head and neck | Q38354192 | ||
Inhibition of Src tyrosine kinase reverts chemoresistance toward 5-fluorouracil in human pancreatic carcinoma cells: an involvement of epidermal growth factor receptor signaling | Q39939411 | ||
Combined inhibition of c-Src and epidermal growth factor receptor abrogates growth and invasion of head and neck squamous cell carcinoma | Q39966334 | ||
Dasatinib inhibits migration and invasion in diverse human sarcoma cell lines and induces apoptosis in bone sarcoma cells dependent on SRC kinase for survival | Q40158315 | ||
Cooperative action of tamoxifen and c-Src inhibition in preventing the growth of estrogen receptor-positive human breast cancer cells | Q40195766 | ||
CHK negatively regulates Lyn kinase and suppresses pancreatic cancer cell invasion. | Q40211304 | ||
Mechanism for Src activation by the CCK2 receptor: Patho-physiological functions of this receptor in pancreas | Q40250328 | ||
Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival | Q40272854 | ||
Dasatinib (BMS-354825) tyrosine kinase inhibitor suppresses invasion and induces cell cycle arrest and apoptosis of head and neck squamous cell carcinoma and non-small cell lung cancer cells | Q40366043 | ||
Inhibition of SRC tyrosine kinase impairs inherent and acquired gemcitabine resistance in human pancreatic adenocarcinoma cells | Q40568614 | ||
Lyn is a target gene for prostate cancer: sequence-based inhibition induces regression of human tumor xenografts | Q40590762 | ||
Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability | Q41714210 | ||
Analysis of the c-src gene product structure, abundance, and protein kinase activity in human neuroblastoma and glioblastoma cells | Q41820222 | ||
Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome-positive leukemia | Q42538832 | ||
Inhibition of SRC tyrosine kinase as treatment for human pancreatic cancer growing orthotopically in nude mice. | Q42820743 | ||
Inducible expression of endothelial PAS domain protein-1 by hypoxia in human lung adenocarcinoma A549 cells. Role of Src family kinases-dependent pathway | Q43829206 | ||
c-Yes tyrosine kinase activity in human colon carcinoma | Q44055120 | ||
Src family kinase activity is required for signal tranducer and activator of transcription 3 and focal adhesion kinase phosphorylation and vascular endothelial growth factor signaling in vivo and for anchorage-dependent and -independent growth of hu | Q44441901 | ||
Natural history and functional divergence of protein tyrosine kinases | Q44646845 | ||
siRNA directed against c-Src enhances pancreatic adenocarcinoma cell gemcitabine chemosensitivity | Q44933975 | ||
Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays. | Q45198729 | ||
Elevated c-yes tyrosine kinase activity in premalignant lesions of the colon | Q46090920 | ||
Overexpression of CEACAM6 promotes insulin-like growth factor I-induced pancreatic adenocarcinoma cellular invasiveness | Q47314747 | ||
Coexpression of IGF-1R and c-Src proteins in human pancreatic ductal adenocarcinoma | Q47375627 | ||
Expression of the lck tyrosine kinase gene in human colon carcinoma and other non-lymphoid human tumor cell lines | Q48339399 | ||
Expression of pp60c-src protein kinase in adult and fetal human tissue: high activities in some sarcomas and mammary carcinomas. | Q52282036 | ||
Estradiol activation of human colon carcinoma-derived Caco-2 cell growth. | Q53451027 | ||
Mutation of the SRC gene in endometrial carcinoma. | Q54964350 | ||
P433 | issue | 7 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 667-78 | |
P577 | publication date | 2009-07-01 | |
P1433 | published in | Oncologist | Q2122327 |
P1476 | title | The role of Src in solid tumors | |
P478 | volume | 14 |
Q35020469 | 1'-Acetoxychavicol acetate suppresses angiogenesis-mediated human prostate tumor growth by targeting VEGF-mediated Src-FAK-Rho GTPase-signaling pathway |
Q38829046 | 4-Hydroxynonenal activates Src through a non-canonical pathway that involves EGFR/PTP1B. |
Q39532016 | A HIF-regulated VHL-PTP1B-Src signaling axis identifies a therapeutic target in renal cell carcinoma |
Q28486292 | A comprehensive, multi-scale dynamical model of ErbB receptor signal transduction in human mammary epithelial cells |
Q50041888 | A first-in-human phase I study to determine the maximum tolerated dose of the oral Src/ABL inhibitor AZD0424. |
Q35007768 | A novel piperazine derivative potently induces caspase-dependent apoptosis of cancer cells via inhibition of multiple cancer signaling pathways |
Q54977394 | A receptor tyrosine kinase ROR1 inhibitor (KAN0439834) induced significant apoptosis of pancreatic cells which was enhanced by erlotinib and ibrutinib. |
Q46752829 | AC-93253 iodide, a novel Src inhibitor, suppresses NSCLC progression by modulating multiple Src-related signaling pathways |
Q24310234 | Activation of Src and transformation by an RPTPα splice mutant found in human tumours |
Q35680450 | Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine (PP2). |
Q35230410 | Adenovirus-mediated delivery of bFGF small interfering RNA reduces STAT3 phosphorylation and induces the depolarization of mitochondria and apoptosis in glioma cells U251. |
Q35818491 | Advances in small-molecule drug discovery for triple-negative breast cancer. |
Q26866135 | Androgen receptor activation in castration-recurrent prostate cancer: the role of Src-family and Ack1 tyrosine kinases |
Q38959078 | Antitumor activity of miR-1280 in melanoma by regulation of Src. |
Q33792131 | Augmentation of the anticancer activity of CYT997 in human prostate cancer by inhibiting Src activity. |
Q36974035 | Aurora-A recruitment and centrosomal maturation are regulated by a Golgi-activated pool of Src during G2 |
Q64298950 | Bisphenol A induces human uterine leiomyoma cell proliferation through membrane-associated ERα36 via nongenomic signaling pathways |
Q37785505 | Bone Metastases: Molecular Mechanisms and Novel Therapeutic Interventions |
Q39536531 | Calmodulin mediates Fas-induced FADD-independent survival signaling in pancreatic cancer cells via activation of Src-extracellular signal-regulated kinase (ERK). |
Q35605121 | Cellular settings mediating Src Substrate switching between focal adhesion kinase tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) tyrosine 734 |
Q34812100 | Combined blockade of Src kinase and epidermal growth factor receptor with gemcitabine overcomes STAT3-mediated resistance of inhibition of pancreatic tumor growth |
Q50636410 | Computational approaches to find the active binding sites of biological targets against busulfan. |
Q44476621 | Covalently grafted VEGF(165) in hydrogel models upregulates the cellular pathways associated with angiogenesis |
Q41292352 | Csk-homologous kinase (Chk) is an efficient inhibitor of Src-family kinases but a poor catalyst of phosphorylation of their C-terminal regulatory tyrosine |
Q35955373 | Cyr61 as mediator of Src signaling in triple negative breast cancer cells. |
Q92336304 | Dasatinib can enhance paclitaxel and gemcitabine inhibitory activity in human pancreatic cancer cells |
Q35919774 | Dasatinib enhances antitumor activity of paclitaxel in ovarian cancer through Src signaling |
Q93350819 | Dasatinib sensitises triple negative breast cancer cells to chemotherapy by targeting breast cancer stem cells |
Q41851428 | Detection of candidate biomarkers of prostate cancer progression in serum: a depletion-free 3D LC/MS quantitative proteomics pilot study. |
Q48016221 | Disrupting the intramolecular interaction between proto-oncogene c-Src SH3 domain and its self-binding peptide PPII with rationally designed peptide ligands |
Q35166355 | Dissecting the cell to nucleus, perinucleus and cytosol. |
Q30009457 | Distinct effects of the mesenchymal dysplasia gene variant of murine Patched-1 protein on canonical and non-canonical Hedgehog signaling pathways |
Q49355253 | Down-regulation of long non-coding RNA ESCCAL_1 inhibits tumor growth of esophageal squamous cell carcinoma in a xenograft mouse model |
Q39363894 | EMT phenotype is induced by increased Src kinase activity via Src-mediated caspase-8 phosphorylation |
Q35904126 | Early Candidate Biomarkers of Non-Small Cell Lung Cancer Are Screened and Identified in Premalignant Lung Lesions |
Q37876194 | Emerging therapeutic approaches in the management of metastatic castration-resistant prostate cancer |
Q37658767 | Emerging therapeutic targets in breast cancer bone metastasis |
Q36228352 | Emerging treatment options for patients with recurrent advanced thymic epithelial tumors |
Q38265286 | Endocytosis and the Src family of non-receptor tyrosine kinases |
Q48442965 | FRK controls migration and invasion of human glioma cells by regulating JNK/c-Jun signaling |
Q26751070 | Filopodia and Viruses: An Analysis of Membrane Processes in Entry Mechanisms |
Q83640823 | First report of the safety, tolerability, and pharmacokinetics of the Src kinase inhibitor saracatinib (AZD0530) in Japanese patients with advanced solid tumours |
Q37826274 | Future directions in castrate-resistant prostate cancer therapy. |
Q51162378 | GAK is phosphorylated by c-Src and translocated from the centrosome to chromatin at the end of telophase. |
Q90240391 | Generation of the configurational ensemble of an intrinsically disordered protein from unbiased molecular dynamics simulation |
Q91677972 | Glycosylation and metastases |
Q26827975 | Growth factor and signaling pathways and their relevance to prostate cancer therapeutics |
Q37774602 | Growth factor signaling pathways as targets for prevention of epithelial carcinogenesis. |
Q38977467 | Growth hormone-releasing hormone antagonists abolish the transactivation of human epidermal growth factor receptors in advanced prostate cancer models. |
Q42676688 | Growth inhibitory effect of the Src inhibitor dasatinib in combination with anticancer agents on uterine cervical adenocarcinoma cells |
Q35665700 | Identification of a Src tyrosine kinase/SIAH2 E3 ubiquitin ligase pathway that regulates C/EBPδ expression and contributes to transformation of breast tumor cells |
Q50420907 | Impact of Phosphoproteomics in the Era of Precision Medicine for Prostate Cancer. |
Q28481644 | In silico investigation of potential SRC kinase ligands from traditional Chinese medicine |
Q37286158 | In silico profiling for secondary metabolites from Lepidium meyenii (maca) by the pharmacophore and ligand-shape-based joint approach |
Q36048506 | Increased Expression of Eps15 Homology Domain 1 is Associated with Poor Prognosis in Resected Small Cell Lung Cancer |
Q52407848 | Integrative network-based approach identifies central genetic and transcriptomic elements in triple-negative breast cancer. |
Q39389243 | Integrin α9β1 promotes malignant tumor growth and metastasis by potentiating epithelial-mesenchymal transition |
Q39078976 | KRAS, NRAS and BRAF mutations in colorectal cancer and melanoma |
Q46965482 | Label-free fluorescence detection of kinase activity using a gold nanoparticle based indicator displacement assay |
Q100316284 | Loss of desmoglein-2 promotes gallbladder carcinoma progression and resistance to EGFR-targeted therapy through Src kinase activation |
Q91312842 | MCL-1 antagonism enhances the anti-invasive effects of dasatinib in pancreatic adenocarcinoma |
Q39365750 | MED28 regulates MEK1-dependent cellular migration in human breast cancer cells |
Q39014809 | Manganese superoxide dismutase-mediated inside-out signaling in HaCaT human keratinocytes and SKH-1 mouse skin |
Q39360651 | Multidrug-resistant cells overexpressing P-glycoprotein are susceptible to DNA crosslinking agents due to attenuated Src/nuclear EGFR cascade-activated DNA repair activity |
Q47373137 | Myeloid cell leukemia 1 (MCL-1), an unexpected modulator of protein kinase signaling during invasion. |
Q38766296 | N-Myristoyltransferase Inhibition Induces ER-Stress, Cell Cycle Arrest, and Apoptosis in Cancer Cells |
Q55014166 | NDRG3 facilitates colorectal cancer metastasis through activating Src phosphorylation. |
Q38591976 | Non-HER2 signaling pathways activated in resistance to anti-HER2 therapy in breast cancer. |
Q38764510 | Novel therapeutic approaches in chondrosarcoma. |
Q42619130 | Oncogenic K-Ras upregulates ITGA6 expression via FOSL1 to induce anoikis resistance and synergizes with αV-Class integrins to promote EMT. |
Q41425790 | Overexpression and knock-down studies highlight that a disintegrin and metalloproteinase 28 controls proliferation and migration in human prostate cancer |
Q33872677 | PRL-3 engages the focal adhesion pathway in triple-negative breast cancer cells to alter actin structure and substrate adhesion properties critical for cell migration and invasion |
Q97539498 | Pharmacophore-based virtual screening for the identification of the novel Src inhibitor SJG-136 against lung cancer cell growth and motility |
Q85076690 | Phase I open-label study of cediranib, an oral inhibitor of VEGF signalling, in combination with the oral Src inhibitor saracatinib in patients with advanced solid tumours |
Q35998482 | Phase I study of saracatinib (AZD0530) in combination with paclitaxel and/or carboplatin in patients with solid tumours |
Q35618896 | Plakophilin-2 induced EGFR phosphorylation: a focus on the intracellular activators of EGFR |
Q64266760 | Plasma proteomic and autoantibody profiles reveal the proteomic characteristics involved in longevity families in Bama, China |
Q34049494 | Posttranscriptional deregulation of Src due to aberrant miR34a and miR203 contributes to gastric cancer development |
Q47704805 | Preclinical modeling of EGFR-specific antibody resistance: oncogenic and immune-associated escape mechanisms. |
Q33832775 | Promotion of Tumor Invasion by Tumor-Associated Macrophages: The Role of CSF-1-Activated Phosphatidylinositol 3 Kinase and Src Family Kinase Motility Signaling |
Q26852215 | Protein-intrinsic and signaling network-based sources of resistance to EGFR- and ErbB family-targeted therapies in head and neck cancer |
Q42679012 | Proteomic profiling of human HepG2 cells treated with hesperidin using antibody array |
Q39415481 | Proteomics analysis of in vitro protein methylation during Src-induced transformation |
Q35116243 | Proteomics: a strategy to understand the novel targets in protein misfolding and cancer therapy |
Q37702696 | Regulation of Src trafficking and activation by the endocytic regulatory proteins MICAL-L1 and EHD1 |
Q27016629 | Resistance and escape from antiangiogenesis therapy: clinical implications and future strategies |
Q35867945 | Retinoic acid reduces migration of human breast cancer cells: role of retinoic acid receptor beta |
Q36413425 | Rhodomycin A, a novel Src-targeted compound, can suppress lung cancer cell progression via modulating Src-related pathways |
Q38647185 | Role of Forkhead Box Class O proteins in cancer progression and metastasis |
Q39479158 | Role of Src in breast cancer cell migration and invasion in a breast cell/bone-derived cell microenvironment |
Q38889500 | Role of cannabinoid receptor CB2 in HER2 pro-oncogenic signaling in breast cancer |
Q39640693 | Role of lymphocyte-specific protein tyrosine kinase (LCK) in the expansion of glioma-initiating cells by fractionated radiation |
Q41637864 | SRC is dephosphorylated at tyrosine 530 in human colon carcinomas |
Q42845234 | SRC kinases in tumor therapy |
Q34993806 | Shikonin induces apoptosis and inhibits migration of ovarian carcinoma cells by inhibiting the phosphorylation of Src and FAK. |
Q26764899 | Signaling Pathways in Thyroid Cancer and Their Therapeutic Implications |
Q46976280 | Silencing Aurora A leads to re-sensitization of breast cancer cells to Taxol through downregulation of SRC-mediated ERK and mTOR pathways |
Q39411794 | Small molecules as activators in medicinal chemistry (2000-2016). |
Q35214722 | Src family kinases and paclitaxel sensitivity |
Q90183151 | Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophy |
Q64269707 | Src inhibition induces melanogenesis in human G361 cells |
Q49787703 | Src is the primary target of aripiprazole, an atypical antipsychotic drug, in its anti-tumor action |
Q37185828 | Src kinases in chondrosarcoma chemoresistance and migration: dasatinib sensitises to doxorubicin in TP53 mutant cells |
Q39584882 | Src: a potential target for the treatment of triple-negative breast cancer |
Q37792074 | Superoxide anion and hydrogen peroxide-induced signaling and damage in angiotensin II and aldosterone action |
Q89441853 | Synergistic Anti-Cancer Effects of AKT and SRC Inhibition in Human Pancreatic Cancer Cells |
Q47222861 | Syntenin mediates SRC function in exosomal cell-to-cell communication |
Q40591054 | Systematic Functional Characterization of Resistance to PI3K Inhibition in Breast Cancer |
Q36253834 | Targeted Inhibition of Src Kinase Signaling Attenuates Pancreatic Tumorigenesis |
Q30008759 | Targeting Self-Binding Peptides as a Novel Strategy To Regulate Protein Activity and Function: A Case Study on the Proto-oncogene Tyrosine Protein Kinase c-Src |
Q37506032 | Targeting the LKB1 tumor suppressor |
Q35896180 | The Notch-mediated hyperplasia circuitry in Drosophila reveals a Src-JNK signaling axis |
Q33881060 | The Src family kinase inhibitor dasatinib delays pain-related behaviour and conserves bone in a rat model of cancer-induced bone pain |
Q36526282 | The Src substrate SKAP2 regulates actin assembly by interacting with WAVE2 and cortactin proteins |
Q64055729 | The expression of Eps15 homology domain 1 is negatively correlated with disease-free survival and overall survival of osteosarcoma patients |
Q28243414 | The interaction between caveolin-1 and Rho-GTPases promotes metastasis by controlling the expression of alpha5-integrin and the activation of Src, Ras and Erk |
Q26852764 | The mechanistic basis of arsenicosis: pathogenesis of skin cancer |
Q26782593 | The molecular effect of metastasis suppressors on Src signaling and tumorigenesis: new therapeutic targets |
Q26853018 | The molecular rationale of Src inhibition in colorectal carcinomas |
Q35832242 | The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1. |
Q35829847 | The use of single-agent dasatinib in molecularly unselected non-small-cell lung cancer patients |
Q37295514 | Trivanillic polyphenols with anticancer cytostatic effects through the targeting of multiple kinases and intracellular Ca2+ release |
Q46915997 | Understanding and targeting resistance mechanisms in NSCLC. |
Q93048656 | Using Small-Angle Scattering Data and Parametric Machine Learning to Optimize Force Field Parameters for Intrinsically Disordered Proteins |
Q36054625 | Yes and Lyn play a role in nuclear translocation of the epidermal growth factor receptor |
Q92276482 | c-Cbl: An Important Regulator and a Target in Angiogenesis and Tumorigenesis |
Q38929142 | c-Src mediated tyrosine phosphorylation of plakophilin 3 as a new mechanism to control desmosome composition in cells exposed to oxidative stress |
Q35228579 | miR-203 suppresses the proliferation and migration and promotes the apoptosis of lung cancer cells by targeting SRC. |
Q36294199 | miR-27b-3p suppresses cell proliferation through targeting receptor tyrosine kinase like orphan receptor 1 in gastric cancer |
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