| scholarly article | Q13442814 |
| P2093 | author name string | I Gout | |
| A M Davies | |||
| G Middleton | |||
| L B Drobot | |||
| N N Ninkina | |||
| M Waterfield | |||
| G Matsuka | |||
| V Filonenko | |||
| J Adu | |||
| V L Buchman | |||
| P2860 | cites work | CMS: an adapter molecule involved in cytoskeletal rearrangements | Q22009896 |
| Cloning and characterization of a novel adaptor protein, CIN85, that interacts with c-Cbl | Q22253208 | ||
| The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
| P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase | Q24322705 | ||
| Interaction of the p85 subunit of PI 3-kinase and its N-terminal SH2 domain with a PDGF receptor phosphorylation site: structural features and analysis of conformational changes | Q24337412 | ||
| Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression system | Q24527428 | ||
| Identification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast | Q24533315 | ||
| The scanning model for translation: an update | Q24679648 | ||
| Crystal structure of a phosphatidylinositol 3-phosphate-specific membrane-targeting motif, the FYVE domain of Vps27p | Q27618582 | ||
| Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains | Q27933286 | ||
| Signaling by distinct classes of phosphoinositide 3-kinases | Q28139034 | ||
| Signalling through phosphoinositide 3-kinases: the lipids take centre stage | Q28141934 | ||
| FYVE fingers bind PtdIns(3)P | Q28279043 | ||
| A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts | Q28282813 | ||
| Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation | Q28286516 | ||
| Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE finger | Q28289331 | ||
| Direct association of Grb2 with the p85 subunit of phosphatidylinositol 3-kinase | Q28302000 | ||
| Akt signaling: linking membrane events to life and death decisions | Q28302851 | ||
| Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunit | Q28508052 | ||
| Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN | Q28513537 | ||
| Differential splicing creates a diversity of transcripts from a neurospecific developmentally regulated gene encoding a protein with new zinc-finger motifs | Q28573433 | ||
| Phosphorylation of cbl after stimulation of Nb2 cells with prolactin and its association with phosphatidylinositol 3-kinase | Q28578666 | ||
| Specificity and promiscuity in phosphoinositide binding by pleckstrin homology domains | Q28584046 | ||
| p21 ras and phosphatidylinositol-3 kinase are required for survival of wild-type and NF1 mutant sensory neurons | Q28587133 | ||
| Persyn, a member of the synuclein family, has a distinct pattern of expression in the developing nervous system | Q28594866 | ||
| New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway | Q29616144 | ||
| Phosphoinositide kinases | Q29618047 | ||
| The GTPase dynamin binds to and is activated by a subset of SH3 domains | Q29618141 | ||
| Intermolecular interactions of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase. | Q30175781 | ||
| Identification of amino acid residues required for a specific interaction between Src-tyrosine kinase and proline-rich region of phosphatidylinositol-3' kinase | Q30176742 | ||
| p120cbl is a cytosolic adapter protein that associates with phosphoinositide 3-kinase in response to epidermal growth factor in PC12 and other cells | Q30192709 | ||
| Recognition and specificity in protein tyrosine kinase-mediated signalling | Q30192978 | ||
| Association of phosphatidylinositol 3-kinase with SHC in chronic myelogeneous leukemia cells. | Q30193531 | ||
| Identification of two SH3-binding motifs in the regulatory subunit of phosphatidylinositol 3-kinase. | Q30194566 | ||
| A region of the 85-kilodalton (kDa) subunit of phosphatidylinositol 3-kinase binds the 110-kDa catalytic subunit in vivo | Q30194817 | ||
| The v-Src SH3 Domain Binds Phosphatidylinositol 3'-Kinase | Q30194840 | ||
| Src-homology 3 domain of protein kinase p59fyn mediates binding to phosphatidylinositol 3-kinase in T cells | Q30194870 | ||
| The role of phosphoinositide 3-kinase lipid products in cell function | Q33543235 | ||
| PTEN: a tumour suppressor that functions as a phospholipid phosphatase | Q33594251 | ||
| Phosphoinositide binding domains: embracing 3-phosphate | Q33684004 | ||
| A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains | Q34436541 | ||
| Ras signalling and apoptosis | Q34746668 | ||
| Phosphatidylinositol 3-kinase activation is mediated by high-affinity interactions between distinct domains within the p110 and p85 subunits | Q36642568 | ||
| Identification of an early endosomal protein regulated by phosphatidylinositol 3-kinase. | Q36655286 | ||
| The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity | Q36745695 | ||
| Phosphoinositide 3-kinases: a conserved family of signal transducers | Q38556727 | ||
| PI 3-kinase: structural and functional analysis of intersubunit interactions | Q40790710 | ||
| The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells | Q40993616 | ||
| Lack of correlation between activation of Jun-NH2-terminal kinase and induction of apoptosis after detachment of epithelial cells | Q41075653 | ||
| Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase | Q41078571 | ||
| Expression and function of TrkB variants in developing sensory neurons. | Q41078653 | ||
| Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase. | Q41105131 | ||
| Signal transduction by the neurotrophin receptors | Q41382912 | ||
| Using structure to define the function of phosphoinositide 3-kinase family members | Q41554112 | ||
| PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond | Q41596068 | ||
| Nerve growth factor promotes the activation of phosphatidylinositol 3-kinase and its association with the trk tyrosine kinase | Q41607684 | ||
| Mechanism of activation and function of protein kinase B. | Q41732739 | ||
| Mechanisms and consequences of activation of protein kinase B/Akt | Q41751003 | ||
| Purification and characterization of a phosphatidylinositol 3-kinase complex from bovine brain by using phosphopeptide affinity columns | Q41787609 | ||
| Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway | Q42618265 | ||
| Requirement for phosphoinositide 3-OH kinase in growth hormone signalling to the mitogen-activated protein kinase and p70s6k pathways | Q42814203 | ||
| Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC. | Q42824933 | ||
| Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons | Q42840914 | ||
| A functional PtdIns(3)P-binding motif | Q47713511 | ||
| Differential mRNA expression and subcellular locations of PI3-kinase isoforms in sympathetic and sensory neurons | Q48229900 | ||
| The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis | Q48301831 | ||
| Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway | Q48617330 | ||
| In sympathetic but not sensory neurones, phosphoinositide-3 kinase is important for NGF-dependent survival and the retrograde transport of 125I-betaNGF. | Q48660267 | ||
| Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells. | Q52177288 | ||
| [Cloning of genes, differentially expressed in the cerebellum during postnatal rat development] | Q52200689 | ||
| Structure and function of phosphoinositide 3-kinases. | Q52532836 | ||
| Phosphatidylinositol 3-Phosphate Recognition by the FYVE Domain | Q57800410 | ||
| Congenital nephrotic syndrome in mice lacking CD2-associated protein | Q57962338 | ||
| The role of PI 3-kinase in insulin action | Q58438150 | ||
| Phosphatidylinositol 3-kinase is activated by nerve growth factor and epidermal growth factor in PC12 cells | Q67854270 | ||
| Role of transforming growth factor-beta isoforms in regulating the expression of nerve growth factor and neurotrophin-3 mRNA levels in embryonic cutaneous cells at different stages of development | Q72106583 | ||
| Activation of phosphatidylinositol 3-kinase through glycoprotein 130 induces protein kinase B and p70 S6 kinase phosphorylation in cardiac myocytes | Q74450488 | ||
| Granulocyte-macrophage colony-stimulating factor-activated signaling pathways in human neutrophils. Involvement of Jak2 in the stimulation of phosphatidylinositol 3-kinase | Q74456595 | ||
| P433 | issue | 15 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 4015-25 | |
| P577 | publication date | 2000-08-01 | |
| P1433 | published in | The EMBO Journal | Q1278554 |
| P1476 | title | Negative regulation of PI 3-kinase by Ruk, a novel adaptor protein | |
| P478 | volume | 19 |
| Q39661773 | A Novel Interaction of the Catalytic Subunit of Protein Phosphatase 2A with the Adaptor Protein CIN85 Suppresses Phosphatase Activity and Facilitates Platelet Outside-in αIIbβ3 Integrin Signaling |
| Q33748546 | A draft of the human septin interactome |
| Q35949097 | A novel function of eIF2alpha kinases as inducers of the phosphoinositide-3 kinase signaling pathway |
| Q44533045 | A screen for E3 ubiquitination ligases that genetically interact with the adaptor protein Cindr during Drosophila eye patterning |
| Q91625840 | ARAP1 Bridges Actin Dynamics and AP-3-Dependent Membrane Traffic in Bone-Digesting Osteoclasts |
| Q30155872 | ARAP1 association with CIN85 affects epidermal growth factor receptor endocytic trafficking |
| Q27639151 | Accessory protein recruitment motifs in clathrin-mediated endocytosis |
| Q33319299 | Adaptor protein Ruk/CIN85 is associated with a subset of COPI-coated membranes of the Golgi complex |
| Q28201193 | Alix (ALG-2-interacting protein X), a protein involved in apoptosis, binds to endophilins and induces cytoplasmic vacuolization |
| Q48159162 | Alix, a protein regulating endosomal trafficking, is involved in neuronal death. |
| Q37527117 | Alix/AIP1 antagonizes epidermal growth factor receptor downregulation by the Cbl-SETA/CIN85 complex. |
| Q37381597 | Altered glycosylation of MUC1 influences its association with CIN85: the role of this novel complex in cancer cell invasion and migration. |
| Q39405747 | Amyloid precursor protein and endosomal-lysosomal dysfunction in Alzheimer's disease: inseparable partners in a multifactorial disease |
| Q50764827 | Association of CD2AP with dynamic actin on vesicles in podocytes. |
| Q30164651 | Atypical recognition consensus of CIN85/SETA/Ruk SH3 domains revealed by target-assisted iterative screening |
| Q40047113 | Binding of influenza A virus NS1 protein to the inter-SH2 domain of p85 suggests a novel mechanism for phosphoinositide 3-kinase activation |
| Q42479754 | CD2-associated protein (CD2AP) expression in podocytes rescues lethality of CD2AP deficiency |
| Q35806658 | CD2AP regulates SUMOylation of CIN85 in podocytes |
| Q53578450 | CD2AP/CIN85 balance determines receptor tyrosine kinase signaling response in podocytes. |
| Q28206219 | CD2AP/CMS regulates endosome morphology and traffic to the degradative pathway through its interaction with Rab4 and c-Cbl |
| Q24337144 | CIN85 associates with multiple effectors controlling intracellular trafficking of epidermal growth factor receptors |
| Q41789207 | CIN85 drives B cell responses by linking BCR signals to the canonical NF-kappaB pathway |
| Q30010282 | CIN85 interacting proteins in B cells-specific role for SHIP-1. |
| Q24338648 | CIN85 is localized at synapses and forms a complex with S-SCAM via dendrin |
| Q30009137 | CIN85 modulates TGFβ signaling by promoting the presentation of TGFβ receptors on the cell surface |
| Q42122822 | CIN85 modulates the down-regulation of Fc gammaRIIa expression and function by c-Cbl in a PKC-dependent manner in human neutrophils |
| Q24304461 | CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases |
| Q24294662 | CIN85, a Cbl-interacting protein, is a component of AMAP1-mediated breast cancer invasion machinery |
| Q30165181 | CIN85/CMS family of adaptor molecules |
| Q39705571 | CIN85/RukL is a novel binding partner of nephrin and podocin and mediates slit diaphragm turnover in podocytes |
| Q27006034 | Capping protein regulators fine-tune actin assembly dynamics |
| Q35818355 | Cargo- and compartment-selective endocytic scaffold proteins |
| Q28207179 | Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors |
| Q24535794 | Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors |
| Q35046114 | Differential effects of P2Y1 and P2Y12 nucleotide receptors on ERK1/ERK2 and phosphatidylinositol 3-kinase signalling and cell proliferation in serum-deprived and nonstarved glioma C6 cells |
| Q30164745 | Epidermal growth factor receptor signaling intensity determines intracellular protein interactions, ubiquitination, and internalization |
| Q28363309 | Expression of the splice variants of the p85alpha regulatory subunit of phosphoinositide 3-kinase in muscle and adipose tissue of healthy subjects and type 2 diabetic patients |
| Q61701718 | Germline deletion of CIN85 in humans with X chromosome-linked antibody deficiency |
| Q57469888 | Human Cytomegalovirus UL135 Interacts with Host Adaptor Proteins To Regulate Epidermal Growth Factor Receptor and Reactivation from Latency |
| Q51190791 | Human homologue of SETA binding protein 1 interacts with cathepsin B and participates in TNF-Induced apoptosis in ovarian cancer cells. |
| Q36967926 | Identification of a novel inhibitory actin-capping protein binding motif in CD2-associated protein. |
| Q30164615 | Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors. |
| Q24321346 | Intersectin 1 forms a complex with adaptor protein Ruk/CIN85 in vivo independently of epidermal growth factor stimulation |
| Q35635353 | JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis |
| Q47407638 | JNK is antagonized to ensure the correct number of interommatidial cells pattern the Drosophila retina |
| Q28190350 | Linking the T Cell Surface Protein CD2 to the Actin-capping Protein CAPZ via CMS and CIN85 |
| Q37968309 | Multiple roles for the p85α isoform in the regulation and function of PI3K signalling and receptor trafficking |
| Q35094638 | Niemann-Pick Type C disease and Alzheimer's disease: the APP-endosome connection fattens up. |
| Q24318683 | Novel insights into the mechanisms of CIN85 SH3 domains binding to Cbl proteins: solution-based investigations and in vivo implications |
| Q30165213 | Organization of the mouse Ruk locus and expression of isoforms in mouse tissues |
| Q30160111 | Overexpression of CIN85 suppresses the growth of herpes simplex virus in HeLa cells |
| Q24304468 | PI3K is negatively regulated by PIK3IP1, a novel p110 interacting protein |
| Q34481485 | Phosphoinositide 3-kinase inhibition in cancer treatment |
| Q28115076 | Phosphorylation of human tristetraprolin in response to its interaction with the Cbl interacting protein CIN85 |
| Q30157225 | Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS. |
| Q24812891 | Regulation of mouse hepatic genes in response to diet induced obesity, insulin resistance and fasting induced weight reduction |
| Q36228479 | Regulation of phosphatidylinositol 3-kinase by polyisoprenyl phosphates in neutrophil-mediated tissue injury. |
| Q24323622 | Rho mediates endocytosis of epidermal growth factor receptor through phosphorylation of endophilin A1 by Rho-kinase |
| Q42947803 | Role of PI 3-kinase, Akt and Bcl-2-related proteins in sustaining the survival of neurotrophic factor-independent adult sympathetic neurons |
| Q28215630 | Ruk is ubiquitinated but not degraded by the proteasome |
| Q38346586 | SAM68: a downstream target of angiotensin II signaling in vascular smooth muscle cells in genetic hypertension |
| Q30010215 | SOX10 regulates expression of the SH3-domain kinase binding protein 1 (Sh3kbp1) locus in Schwann cells via an alternative promoter |
| Q30160396 | Src phosphorylation of Alix/AIP1 modulates its interaction with binding partners and antagonizes its activities |
| Q35006094 | Structures, functions and molecular evolution of the penta-EF-hand Ca2+-binding proteins |
| Q36232734 | T-cell activation and immunologic synapse |
| Q24308624 | The ALG-2-interacting protein Alix associates with CHMP4b, a human homologue of yeast Snf7 that is involved in multivesicular body sorting |
| Q28277251 | The Cbl interactome and its functions |
| Q36534633 | The Drosophila CD2AP/CIN85 orthologue Cindr regulates junctions and cytoskeleton dynamics during tissue patterning |
| Q27714533 | The adaptor protein CIN85 assembles intracellular signaling clusters for B cell activation |
| Q30155954 | The interactome of a PTB domain-containing adapter protein, Odin, revealed by SILAC |
| Q36119393 | The ubiquitin-proteasome system and the autophagic-lysosomal system in Alzheimer disease |
| Q35791541 | Up-regulation of ALG-2 in hepatomas and lung cancer tissue |
| Q34415888 | p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes |
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