| scholarly article | Q13442814 |
| P2093 | author name string | J H Hurley | |
| L M Burden | |||
| Y S Ho | |||
| P2860 | cites work | Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP | Q22008544 |
| Binding of cGMP to both allosteric sites of cGMP-binding cGMP-specific phosphodiesterase (PDE5) is required for its phosphorylation | Q24530647 | ||
| SMART, a simple modular architecture research tool: identification of signaling domains | Q24597380 | ||
| Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A | Q24676441 | ||
| Improved methods for building protein models in electron density maps and the location of errors in these models | Q26776980 | ||
| Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination | Q26778405 | ||
| Processing of X-ray diffraction data collected in oscillation mode | Q26778468 | ||
| Anomalous signal of solvent bromides used for phasing of lysozyme | Q27618330 | ||
| Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains | Q27729819 | ||
| 1.4 A structure of photoactive yellow protein, a cytosolic photoreceptor: unusual fold, active site, and chromophore | Q27730238 | ||
| The structure of crystalline profilin-beta-actin | Q27732069 | ||
| Combination of threading potentials and sequence profiles improves fold recognition. | Q52081617 | ||
| Molecular clocks: mastering time by gene regulation | Q58987847 | ||
| Molecular model of the cyclic GMP-binding domain of the cyclic GMP-gated ion channel | Q67488221 | ||
| Characterization of a purified bovine lung cGMP-binding cGMP phosphodiesterase | Q67669457 | ||
| Identification of key amino acids in a conserved cGMP-binding site of cGMP-binding phosphodiesterases. A putative NKXnD motif for cGMP binding | Q71246713 | ||
| Studies of the molecular mechanism of discrimination between cGMP and cAMP in the allosteric sites of the cGMP-binding cGMP-specific phosphodiesterase (PDE5) | Q73041166 | ||
| Novel approach to phasing proteins: derivatization by short cryo-soaking with halides | Q73427869 | ||
| The crystal structure of a major allergen from plants | Q27734729 | ||
| Structure at 0.85 A resolution of an early protein photocycle intermediate | Q27748967 | ||
| Crystal structure and functional analysis of the HERG potassium channel N terminus: a eukaryotic PAS domain | Q27766251 | ||
| Structure of a biological oxygen sensor: a new mechanism for heme-driven signal transduction | Q27766366 | ||
| Dali: a network tool for protein structure comparison | Q27860617 | ||
| Methods used in the structure determination of bovine mitochondrial F1 ATPase | Q27860644 | ||
| Heterozygous missense mutation in the rod cGMP phosphodiesterase beta-subunit gene in autosomal dominant stationary night blindness | Q28247337 | ||
| PAS: a multifunctional domain family comes to light | Q28255418 | ||
| Pfam 3.1: 1313 multiple alignments and profile HMMs match the majority of proteins | Q28291030 | ||
| Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase | Q28368278 | ||
| Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A | Q28593446 | ||
| SURFNET: a program for visualizing molecular surfaces, cavities, and intermolecular interactions | Q29615882 | ||
| Overcoming expression and purification problems of RhoGDI using a family of "parallel" expression vectors | Q29617999 | ||
| Surprising similarities in structure comparison | Q29620326 | ||
| Threading with explicit models for evolutionary conservation of structure and sequence | Q30794963 | ||
| How photons start vision | Q33562392 | ||
| Cyclic GMP phosphodiesterase-5: target of sildenafil | Q33630333 | ||
| Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions | Q33860484 | ||
| cGMP binding to noncatalytic sites on mammalian rod photoreceptor phosphodiesterase is regulated by binding of its gamma and delta subunits | Q33865353 | ||
| The molecular basis of hypertension | Q33953544 | ||
| Structure of catabolite gene activator protein at 2.9 A resolution suggests binding to left-handed B-DNA. | Q34055138 | ||
| The GAF domain: an evolutionary link between diverse phototransducing proteins. | Q34452640 | ||
| Photoactive yellow protein: a structural prototype for the three-dimensional fold of the PAS domain superfamily. | Q36253543 | ||
| Visual excitation and recovery | Q36652812 | ||
| Control of ligand specificity in cyclic nucleotide-gated channels from rod photoreceptors and olfactory epithelium | Q37614909 | ||
| Identification of a noncatalytic cGMP-binding domain conserved in both the cGMP-stimulated and photoreceptor cyclic nucleotide phosphodiesterases | Q37664394 | ||
| An essential aspartic acid at each of two allosteric cGMP-binding sites of a cGMP-specific phosphodiesterase | Q38287777 | ||
| One amino acid change produces a high affinity cGMP-binding site in cAMP-dependent protein kinase. | Q38339104 | ||
| Molecular mechanisms and therapeutic strategies related to nitric oxide. | Q40413002 | ||
| Phytochromes: photosensory perception and signal transduction | Q40514710 | ||
| Probing domain functions of chimeric PDE6alpha'/PDE5 cGMP-phosphodiesterase. | Q41009849 | ||
| Nitric oxide-cyclic GMP signal transduction system. | Q41100343 | ||
| Regulation of photoreceptor phosphodiesterase catalysis by its non-catalytic cGMP-binding sites | Q42473039 | ||
| Similarity of a chromatic adaptation sensor to phytochrome and ethylene receptors | Q42634176 | ||
| Structure and function studies of the cGMP-stimulated phosphodiesterase | Q43585489 | ||
| Predicted structures of the cGMP binding domains of the cGMP-dependent protein kinase: a key alanine/threonine difference in evolutionary divergence of cAMP and cGMP binding sites | Q43865344 | ||
| A clockwork explosion! | Q47713140 | ||
| CikA, a bacteriophytochrome that resets the cyanobacterial circadian clock | Q47840229 | ||
| The 1996 Albert Lasker Medical Research Awards. Signal transduction using nitric oxide and cyclic guanosine monophosphate | Q48386736 | ||
| P433 | issue | 20 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 5288-99 | |
| P577 | publication date | 2000-10-16 | |
| P1433 | published in | The EMBO Journal | Q1278554 |
| P1476 | title | Structure of the GAF domain, a ubiquitous signaling motif and a new class of cyclic GMP receptor | |
| P478 | volume | 19 |
| Q27652745 | 2.3 A X-ray structure of the heme-bound GAF domain of sensory histidine kinase DosT of Mycobacterium tuberculosis |
| Q41782296 | 5S clavam biosynthesis is controlled by an atypical two-component regulatory system in Streptomyces clavuligerus |
| Q39647700 | A GAF-domain-regulated adenylyl cyclase from Anabaena is a self-activating cAMP switch |
| Q27631238 | A novel snare N-terminal domain revealed by the crystal structure of Sec22b |
| Q39726110 | A two-component regulator of universal stress protein expression and adaptation to oxygen starvation in Mycobacterium smegmatis |
| Q34498057 | ANTAR: an RNA-binding domain in transcription antitermination regulatory proteins |
| Q42241297 | Analysis of the functional conservation of ethylene receptors between maize and Arabidopsis |
| Q46899988 | Analysis of the nitric oxide-sensing non-heme iron center in the NorR regulatory protein. |
| Q24798253 | Ancient conserved domains shared by animal soluble guanylyl cyclases and bacterial signaling proteins |
| Q34655886 | Bacterial growth and cell division: a mycobacterial perspective |
| Q37830693 | Bacterial phytochromes: more than meets the light |
| Q31061113 | Bacterial signal transduction network in a genomic perspective |
| Q38363670 | Binding of cGMP to GAF domains in amphibian rod photoreceptor cGMP phosphodiesterase (PDE). Identification of GAF domains in PDE alphabeta subunits and distinct domains in the PDE gamma subunit involved in stimulation of cGMP binding to GAF domains |
| Q44355336 | Biochemical properties of CikA, an unusual phytochrome-like histidine protein kinase that resets the circadian clock in Synechococcus elongatus PCC 7942. |
| Q28551212 | Cache Domains That are Homologous to, but Different from PAS Domains Comprise the Largest Superfamily of Extracellular Sensors in Prokaryotes |
| Q83322995 | Characterization of the tandem GAF domain of human phosphodiesterase 5 using a cyanobacterial adenylyl cyclase as a reporter enzyme |
| Q35080979 | Characterization of the yehUT two-component regulatory system of Salmonella enterica Serovar Typhi and Typhimurium. |
| Q24649959 | Chloroplast two-component systems: evolution of the link between photosynthesis and gene expression |
| Q34331215 | Comparative analysis of diguanylate cyclase and phosphodiesterase genes in Klebsiella pneumoniae. |
| Q21265030 | Comparative genomic analysis of two-component regulatory proteins in Pseudomonas syringae |
| Q35197965 | Control of eukaryotic membrane fusion by N-terminal domains of SNARE proteins. |
| Q93515647 | Corrigenda |
| Q28487457 | Cross talk between DevS sensor kinase homologue, Rv2027c, and DevR response regulator of Mycobacterium tuberculosis |
| Q27680495 | Crystal structure of an HD-GYP domain cyclic-di-GMP phosphodiesterase reveals an enzyme with a novel trinuclear catalytic iron centre |
| Q27650596 | Crystal structure of the GAF-B domain from human phosphodiesterase 10A complexed with its ligand, cAMP |
| Q34720154 | Cyanobacterial two-component proteins: structure, diversity, distribution, and evolution |
| Q36545487 | Cyanobacteriochromes in full color and three dimensions. |
| Q26850396 | Cyclic di-GMP: the first 25 years of a universal bacterial second messenger |
| Q40698430 | Cyclic diguanylate regulation of Bacillus cereus group biofilm formation |
| Q33571750 | Cyclic nucleotide binding GAF domains from phosphodiesterases: structural and mechanistic insights |
| Q21284279 | Cyclic nucleotide binding proteins in the Arabidopsis thaliana and Oryza sativa genomes |
| Q34467066 | Cyclic nucleotide phosphodiesterases and their role in endocrine cell signaling. |
| Q36334968 | Cyclic nucleotide phosphodiesterases as targets for treatment of haematological malignancies |
| Q28492671 | Dcsbis (PA2771) from Pseudomonas aeruginosa is a highly active diguanylate cyclase with unique activity regulation |
| Q91816956 | Differential impact on motility and biofilm dispersal of closely related phosphodiesterases in Pseudomonas aeruginosa |
| Q38411339 | Dissection of the HOG pathway activated by hydrogen peroxide in Saccharomyces cerevisiae |
| Q37200753 | Distribution, structure and diversity of "bacterial" genes encoding two-component proteins in the Euryarchaeota |
| Q34768956 | Domain architectures of sigma54-dependent transcriptional activators |
| Q42029663 | Effect of point mutations on Herbaspirillum seropedicae NifA activity |
| Q33789962 | Engineering of a red-light-activated human cAMP/cGMP-specific phosphodiesterase. |
| Q28293257 | Ethanolamine activates a sensor histidine kinase regulating its utilization in Enterococcus faecalis |
| Q34084437 | Ethylene hormone receptor action in Arabidopsis |
| Q42025191 | Evidence of in vivo cross talk between the nitrogen-related and fructose-related branches of the carbohydrate phosphotransferase system of Pseudomonas putida |
| Q87610005 | Evolution of PAS domains and PAS-containing genes in eukaryotes |
| Q33627357 | Evolutionary history of redox metal-binding domains across the tree of life |
| Q35807241 | Flagellar radial spoke protein 2 is a calmodulin binding protein required for motility in Chlamydomonas reinhardtii |
| Q35834492 | Free methionine-(R)-sulfoxide reductase from Escherichia coli reveals a new GAF domain function |
| Q27931261 | Functional analysis of free methionine-R-sulfoxide reductase from Saccharomyces cerevisiae |
| Q50715694 | Functional and biochemical analysis of the N-terminal domain of phytochrome A. |
| Q24633361 | Functions and evolution of selenoprotein methionine sulfoxide reductases |
| Q35041198 | GAF domains: cyclic nucleotides come full circle |
| Q36506399 | Gene expression profiles at different stages of human esophageal squamous cell carcinoma |
| Q28085365 | General Stress Signaling in the Alphaproteobacteria |
| Q34334558 | Genetic regulation of biological nitrogen fixation |
| Q90494776 | Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks |
| Q37152109 | Genome features of Leptospira interrogans serovar Copenhageni |
| Q58802857 | Genome-Wide Identification and Characterization of Family Genes in |
| Q33304398 | Genome-wide survey of putative serine/threonine protein kinases in cyanobacteria |
| Q37713921 | Harnessing phytochrome's glowing potential |
| Q89891233 | Highly-regulated, diversifying NTP-based biological conflict systems with implications for emergence of multicellularity |
| Q28365856 | HstK, a cyanobacterial protein with both a serine/threonine kinase domain and a histidine kinase domain: implication for the mechanism of signal transduction |
| Q28854123 | Identification of RamA, a novel LuxR-type transcriptional regulator of genes involved in acetate metabolism of Corynebacterium glutamicum. |
| Q34067409 | Identification of four candidate cGMP targets in Dictyostelium |
| Q44580163 | In silico analysis of the sigma54-dependent enhancer-binding proteins in Pirellula species strain 1. |
| Q42412170 | Integration of rotation and piston motions in coiled-coil signal transduction |
| Q34655655 | Inter-kingdom signalling: communication between bacteria and their hosts |
| Q36421918 | Interaction of Bacillus subtilis CodY with GTP. |
| Q36194934 | Interactions between diatoms and bacteria |
| Q38271925 | Internal sense of direction: sensing and signaling from cytoplasmic chemoreceptors |
| Q33741265 | Iron-based redox switches in biology |
| Q61449530 | Key Players and Individualists of Cyclic-di-GMP Signaling in |
| Q55239768 | Kinome Expansion in the Fusarium oxysporum Species Complex Driven by Accessory Chromosomes. |
| Q34191590 | Ligand-binding PAS domains in a genomic, cellular, and structural context |
| Q50777025 | Light-induced global structural changes in phytochrome A regulating photomorphogenesis in plants. |
| Q44943882 | Longin and GAF domains: structural evolution and adaptation to the subcellular trafficking machinery |
| Q28579640 | Mammalian ykt6 is a neuronal SNARE targeted to a specialized compartment by its profilin-like amino terminal domain |
| Q24336151 | Mechanism for the allosteric regulation of phosphodiesterase 2A deduced from the X-ray structure of a near full-length construct |
| Q36393878 | Members of the IclR family of bacterial transcriptional regulators function as activators and/or repressors |
| Q58708568 | Methionine Sulfoxide Reductases of Archaea |
| Q44371553 | Modeling and mutational analysis of the GAF domain of the cGMP-binding, cGMP-specific phosphodiesterase, PDE5. |
| Q28268016 | Molecular determinants for cyclic nucleotide binding to the regulatory domains of phosphodiesterase 2A |
| Q45032473 | Molecular determinants of cGMP binding to chicken cone photoreceptor phosphodiesterase |
| Q27644084 | Molecular insights into quorum sensing in the human pathogen Pseudomonas aeruginosa from the structure of the virulence regulator LasR bound to its autoinducer |
| Q34293819 | Multiple roles of a conserved GAF domain tyrosine residue in cyanobacterial and plant phytochromes |
| Q39680888 | Mutant forms of the Azotobacter vinelandii transcriptional activator NifA resistant to inhibition by the NifL regulatory protein. |
| Q54430922 | Nitrate signaling by the regulatory gene NIT2 in Chlamydomonas. |
| Q43184106 | Novel arrangement of enhancer sequences for NifA-dependent activation of the hydrogenase gene promoter in Rhizobium leguminosarum bv. viciae |
| Q64120783 | Nucleotide Second Messenger-Based Signaling in Extreme Acidophiles of the Species Complex: Partition Between the Core and Variable Gene Complements |
| Q37873545 | Oxidation-reduction signalling components in regulatory pathways of state transitions and photosystem stoichiometry adjustment in chloroplasts |
| Q75209504 | Phasing on rapidly soaked ions |
| Q34776677 | Phytochrome ancestry: sensors of bilins and light. |
| Q37343084 | Proteome analysis of Plasmodium falciparum extracellular secretory antigens at asexual blood stages reveals a cohort of proteins with possible roles in immune modulation and signaling |
| Q43879654 | Quantitative monitoring of 2-oxoglutarate in Escherichia coli cells by a fluorescence resonance energy transfer-based biosensor |
| Q34579810 | Quinone sensing by the circadian input kinase of the cyanobacterial circadian clock |
| Q44235703 | Radiation response in Deinococcus deserti: IrrE is a metalloprotease that cleaves repressor protein DdrO. |
| Q30885931 | Rapid protein fold determination using unassigned NMR data |
| Q37846550 | Receptor domains of two-component signal transduction systems. |
| Q51723155 | Receptor signal output mediated by the ETR1 N terminus is primarily subfamily I receptor dependent. |
| Q35905342 | Redox-dependent Ligand Switching in a Sensory Heme-binding GAF Domain of the Cyanobacterium Nostoc sp. PCC7120. |
| Q24656979 | Roles of cyclic diguanylate in the regulation of bacterial pathogenesis |
| Q38362889 | Secondary structure and DNA binding by the C-terminal domain of the transcriptional activator NifA from Klebsiella pneumoniae. |
| Q30153489 | Secondary structure and rigidity in model proteins. |
| Q36328080 | Sensor complexes regulating two-component signal transduction |
| Q37707671 | Sensor domains of two-component regulatory systems |
| Q24652869 | Shedding light on adaptation |
| Q27650760 | Solution Structure of the cGMP Binding GAF Domain from Phosphodiesterase 5: INSIGHTS INTO NUCLEOTIDE SPECIFICITY, DIMERIZATION, AND cGMP-DEPENDENT CONFORMATIONAL CHANGE |
| Q43826566 | Specific cGMP binding by the cGMP binding domains of cGMP-binding cGMP specific phosphodiesterase |
| Q27674966 | Structural Mechanism of GAF-Regulated σ54 Activators from Aquifex aeolicus |
| Q27661762 | Structural and Biochemical Characterization of Free Methionine-R-sulfoxide Reductase from Neisseria meningitidis |
| Q90029462 | Structural and functional insight into the Mycobacterium tuberculosis protein PrpR reveals a novel type of transcription factor |
| Q38485080 | Structural and kinetic analysis of free methionine-R-sulfoxide reductase from Staphylococcus aureus: conformational changes during catalysis and implications for the catalytic and inhibitory mechanisms |
| Q61800419 | Structural basis of DSF recognition by its receptor RpfR and its regulatory interaction with the DSF synthase RpfF |
| Q33245450 | Structural classification of bacterial response regulators: diversity of output domains and domain combinations |
| Q34498078 | Structural genomics and signaling domains. |
| Q37549400 | Structural interface parameters are discriminatory in recognising near-native poses of protein-protein interactions |
| Q35084439 | Structural rearrangement accompanying ligand binding in the GAF domain of CodY from Bacillus subtilis. |
| Q33205260 | Structure and expression of maize phytochrome family homeologs. |
| Q35008317 | Structure and signaling mechanism of Per-ARNT-Sim domains |
| Q27670796 | Structures of the PelD Cyclic Diguanylate Effector Involved in Pellicle Formation in Pseudomonas aeruginosa PAO1 |
| Q38848058 | The CasKR two-component system is required for the growth of mesophilic and psychrotolerant Bacillus cereus strains at low temperatures |
| Q45221882 | The Legionella pneumophila Incomplete Phosphotransferase System Is Required for Optimal Intracellular Growth and Maximal Expression of PmrA-Regulated Effectors |
| Q35632122 | The NifL-NifA System: a multidomain transcriptional regulatory complex that integrates environmental signals. |
| Q39680002 | The NorR protein of Escherichia coli activates expression of the flavorubredoxin gene norV in response to reactive nitrogen species |
| Q39394846 | The amino-terminal GAF domain of Azotobacter vinelandii NifA binds 2-oxoglutarate to resist inhibition by NifL under nitrogen-limiting conditions. |
| Q36895687 | The arabidopsis cyclic nucleotide interactome |
| Q34416191 | The autoinducer-2 exporter superfamily |
| Q34047854 | The cAMP-specific phosphodiesterase TbPDE2C is an essential enzyme in bloodstream form Trypanosoma brucei |
| Q43619021 | The catalytic and GAF domains of the rod cGMP phosphodiesterase (PDE6) heterodimer are regulated by distinct regions of its inhibitory gamma subunit |
| Q27639533 | The crystal structure of the quorum sensing protein TraR bound to its autoinducer and target DNA |
| Q33865137 | The cyanobacterial tandem GAF domains from the cyaB2 adenylyl cyclase signal via both cAMP-binding sites |
| Q26864476 | The methionine sulfoxide reduction system: selenium utilization and methionine sulfoxide reductase enzymes and their functions |
| Q28492488 | The phosphodiesterase DipA (PA5017) is essential for Pseudomonas aeruginosa biofilm dispersion |
| Q38225515 | The plant RWP-RK transcription factors: key regulators of nitrogen responses and of gametophyte development |
| Q36445794 | The prenyl-binding protein PrBP/δ: a chaperone participating in intracellular trafficking |
| Q38039049 | The role of bacterial enhancer binding proteins as specialized activators of σ54-dependent transcription |
| Q46952678 | The structure of CodY, a GTP- and isoleucine-responsive regulator of stationary phase and virulence in gram-positive bacteria |
| Q36357907 | The structure of phytochrome: a picture is worth a thousand spectra. |
| Q27641688 | The structure of the periplasmic ligand-binding domain of the sensor kinase CitA reveals the first extracellular PAS domain |
| Q24538689 | The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding |
| Q40412632 | Thermoregulation of Biofilm Formation in Burkholderia pseudomallei Is Disrupted by Mutation of a Putative Diguanylate Cyclase |
| Q44173688 | Three-dimensional structure of non-activated cGMP phosphodiesterase 6 and comparison of its image with those of activated forms |
| Q30331197 | Trends in protein evolution inferred from sequence and structure analysis. |
| Q53734024 | Two histidine kinases can sense different stress cues for activation of the MAPK Hog1 in a fungal insect pathogen. |
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