A critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathy

scientific article

A critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathy is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M109.077610
P3181OpenCitations bibliographic resource ID845630
P932PMC publication ID2856297
P698PubMed publication ID20110366

P50authorAnthony H. FutermanQ41388875
Shifra Ben-DorQ41607461
P2093author name stringAlfred H Merrill
Shifra Ben-Dor
Abraham Nyska
Tamara Berkutzki
Elad L Laviad
Hyejung Park
Racheli Erez-Roman
Yael Pewzner-Jung
Shirley Horn-Saban
Ester Feldmesser
Ori Brenner
Michal Levy
Calanit Raanan
Oshrit Ben-David
Daniela Amann-Zalcenstein
Dorin Holzman
Svantje Braun
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Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant miceQ28512884
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BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosisQ28594183
Sphingolipid functions in Saccharomyces cerevisiaeQ28679249
The significance of digital gene expression profilesQ29614357
Adult ceramide synthase 2 (CERS2)-deficient mice exhibit myelin sheath defects, cerebellar degeneration, and hepatocarcinomasQ30492014
A vital role for glycosphingolipid synthesis during development and differentiationQ30748450
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A critical role for ceramide synthase 2 in liver homeostasis: I. alterations in lipid metabolic pathwaysQ33796283
Implications of apoptosis for toxicity, carcinogenicity, and risk assessment: fumonisin B(1) as an exampleQ34213849
Defects in cell growth regulation by C18:0-ceramide and longevity assurance gene 1 in human head and neck squamous cell carcinomasQ34341991
Differential sensitivity of rat kidney and liver to fumonisin toxicity: organ-specific differences in toxin accumulation and sphingoid base metabolismQ34513658
When do Lasses (longevity assurance genes) become CerS (ceramide synthases)?: Insights into the regulation of ceramide synthesisQ34541094
Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphateQ34731468
De novo N-palmitoylsphingosine synthesis is the major biochemical mechanism of ceramide accumulation following p53 up-regulation.Q34768921
Ceramide synthases and ceramide levels are increased in breast cancer tissueQ34961114
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Sphingolipidomics: high-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometryQ36127968
Disruption of ceramide synthesis by CerS2 down-regulation leads to autophagy and the unfolded protein response.Q36155852
Lipid mediators of insulin resistanceQ36867145
Sorafenib and vorinostat kill colon cancer cells by CD95-dependent and -independent mechanismsQ37268127
Role of very long fatty acid-containing glycosphingolipids in membrane organization and cell signaling: the model of lactosylceramide in neutrophils.Q37328078
Sumoylated PPARalpha mediates sex-specific gene repression and protects the liver from estrogen-induced toxicity in miceQ37363062
Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomasQ40169778
Mass spectrometric identification of increased C16 ceramide levels during apoptosisQ40922788
Characterization of cell-cycle arrest by fumonisin B1 in CV-1 cellsQ41008881
Ceramide biogenesis is required for radiation-induced apoptosis in the germ line of C. elegansQ42936816
Analysis of sphingosine 1-phosphate, ceramides, and other bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometryQ43830323
Comments on R. Karbe and R. L. Kerlin (2002). Cystic degeneration/spongiosis hepatis (Toxicol Pathol 30 (2), 216-227).Q44704100
Multiple adaptive mechanisms to chronic liver disease revealed at early stages of liver carcinogenesis in the Mdr2-knockout miceQ45857462
Classification of proliferative hepatocellular lesions in harlan sprague-dawley rats chronically exposed to dioxin-like compounds.Q46417388
The relationship among microsomal enzyme induction, liver weight and histological change in rat toxicology studiesQ47281524
Fumonisins: fungal toxins that shed light on sphingolipid functionQ47986534
Protection of C. elegans from anoxia by HYL-2 ceramide synthaseQ47995901
Liver gene expression analysis reveals endoplasmic reticulum stress and metabolic dysfunction in SCD1-deficient mice fed a very low-fat diet.Q50082945
Toxicity of fumonisin B1 to B6C3F1 mice: a 14-day gavage study.Q50908586
Toxicology and carcinogenesis studies of fumonisin B1 (cas no. 116355-83-0) in F344/N rats and B6C3F1 mice (feed studies)Q51540082
Incretin receptors for glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide are essential for the sustained metabolic actions of vildagliptin in mice.Q53532607
Regulation of cyclin-dependent kinase inhibitor p21(WAF1/Cip1/Sdi1) gene expression in hepatic regenerationQ73107788
P433issue14
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
ceramidesQ424213
P304page(s)10911-23
P577publication date2010-04-02
P1433published inJournal of Biological ChemistryQ867727
P1476titleA critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathy
P478volume285

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