| scholarly article | Q13442814 |
| P50 | author | Adriana Haimovitz-Friedman | Q63367471 |
| P2093 | author name string | Shai Shaham | |
| Richard Allan | |||
| Richard Kolesnick | |||
| Zvi Fuks | |||
| Carine W Maurer | |||
| Diane D Lu | |||
| Xianglei Yin | |||
| Xinzhu Deng | |||
| P2860 | cites work | Necessary role for the Lag1p motif in (dihydro)ceramide synthase activity | Q24301554 |
| The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9 | Q28272159 | ||
| C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage | Q28298792 | ||
| C. elegans dynamin-related protein DRP-1 controls severing of the mitochondrial outer membrane | Q29620388 | ||
| When do Lasses (longevity assurance genes) become CerS (ceramide synthases)?: Insights into the regulation of ceramide synthesis | Q34541094 | ||
| Physiological and pathophysiological aspects of ceramide | Q36341274 | ||
| Biophysics of sphingolipids I. Membrane properties of sphingosine, ceramides and other simple sphingolipids. | Q36637060 | ||
| Nonapoptotic role for Apaf-1 in the DNA damage checkpoint | Q40043968 | ||
| Loss of sphingosine kinase-1 activates the intrinsic pathway of programmed cell death: modulation of sphingolipid levels and the induction of apoptosis. | Q40310350 | ||
| Caenorhabditis elegans ABL-1 antagonizes p53-mediated germline apoptosis after ionizing irradiation | Q40531878 | ||
| Ceramide in apoptosis--does it really matter? | Q40995773 | ||
| The 55-kDa tumor necrosis factor receptor induces clustering of mitochondria through its membrane-proximal region | Q41041349 | ||
| Conversion of dihydroceramide into ceramide: involvement of a desaturase | Q42987974 | ||
| Disruption of the CED-9.CED-4 complex by EGL-1 is a critical step for programmed cell death in Caenorhabditis elegans. | Q47069096 | ||
| Structural, biochemical, and functional analyses of CED-9 recognition by the proapoptotic proteins EGL-1 and CED-4. | Q47069176 | ||
| Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis | Q47069226 | ||
| Translocation of C. elegans CED-4 to nuclear membranes during programmed cell death | Q47069246 | ||
| A conserved checkpoint pathway mediates DNA damage--induced apoptosis and cell cycle arrest in C. elegans | Q47069275 | ||
| CED-4 forms a 2 : 2 heterotetrameric complex with CED-9 until specifically displaced by EGL-1 or CED-13 | Q58072502 | ||
| P433 | issue | 5898 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Caenorhabditis elegans | Q91703 |
| ceramides | Q424213 | ||
| apoptotic process | Q14599311 | ||
| P304 | page(s) | 110-115 | |
| P577 | publication date | 2008-10-01 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Ceramide biogenesis is required for radiation-induced apoptosis in the germ line of C. elegans | |
| P478 | volume | 322 |
| Q24634622 | A critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathy |
| Q36864868 | A novel sphingolipid-TORC1 pathway critically promotes postembryonic development in Caenorhabditis elegans |
| Q47712397 | A search for ceramide binding proteins using bifunctional lipid analogs yields CERT-related protein StarD7. |
| Q27317086 | ASM-3 acid sphingomyelinase functions as a positive regulator of the DAF-2/AGE-1 signaling pathway and serves as a novel anti-aging target |
| Q38009932 | Anti-apoptotic and anti-oxidative mechanisms of minocycline against sphingomyelinase/ceramide neurotoxicity: implication in Alzheimer's disease and cerebral ischemia |
| Q33552843 | Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways |
| Q93081361 | Associations of circulating very-long-chain saturated fatty acids and incident type 2 diabetes: a pooled analysis of prospective cohort studies |
| Q36813008 | BAK activation is necessary and sufficient to drive ceramide synthase-dependent ceramide accumulation following inhibition of BCL2-like proteins |
| Q92504639 | Biosynthesis of long chain base in sphingolipids in animals, plants and fungi |
| Q57295410 | C-ceramide is a natural regulatory ligand of p53 in cellular stress response |
| Q35106336 | C. elegans CEP-1/p53 and BEC-1 are involved in DNA repair |
| Q33915292 | Caenorhabditis elegans pathways that surveil and defend mitochondria |
| Q57495845 | Cardiovascular Implications of Sphingomyelin Presence in Biological Membranes |
| Q37120912 | Cell biology. Ceramides--friend or foe in hypoxia? |
| Q90642065 | Ceramide Signaling and p53 Pathways |
| Q37970353 | Ceramide and mitochondria in ischemic brain injury. |
| Q37797406 | Ceramide in stress response |
| Q41488650 | Ceramide phosphoethanolamine synthase SMSr is a target of caspase-6 during apoptotic cell death. |
| Q34963246 | Ceramide synthase-dependent ceramide generation and programmed cell death: involvement of salvage pathway in regulating postmitochondrial events |
| Q41995354 | Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells |
| Q38472485 | Ceramide synthases in mammalians, worms, and insects: emerging schemes |
| Q33703218 | Ceramide synthesis regulates T cell activity and GVHD development |
| Q36946878 | Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy |
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| Q37625507 | Death upon a kiss: mitochondrial outer membrane composition and organelle communication govern sensitivity to BAK/BAX-dependent apoptosis |
| Q41259681 | Developmental abnormality induced by strong static magnetic field in Caenorhabditis elegans |
| Q34575828 | Developmentally regulated ceramide synthase 6 increases mitochondrial Ca2+ loading capacity and promotes apoptosis |
| Q35006514 | Distribution and functions of sterols and sphingolipids |
| Q61797549 | Effects of Co γ Irradiation on the Reproductive Function of |
| Q42142132 | Endothelial cells regulate p53-dependent apoptosis of neural progenitors after irradiation |
| Q30505349 | Evidence that CED-9/Bcl2 and CED-4/Apaf-1 localization is not consistent with the current model for C. elegans apoptosis induction |
| Q38240473 | Exploring the link between ceramide and ionizing radiation |
| Q27310570 | Functional loss of two ceramide synthases elicits autophagy-dependent lifespan extension in C. elegans |
| Q30301364 | Genetic loci associated with circulating levels of very long-chain saturated fatty acids |
| Q30823934 | Glucose or Altered Ceramide Biosynthesis Mediate Oxygen Deprivation Sensitivity Through Novel Pathways Revealed by Transcriptome Analysis in Caenorhabditis elegans. |
| Q92043665 | High-glucose diets induce mitochondrial dysfunction in Caenorhabditis elegans |
| Q34568175 | Hydrophobic analogues of rhodamine B and rhodamine 101: potent fluorescent probes of mitochondria in living C. elegans |
| Q28590499 | Identification and characterization of murine mitochondria-associated neutral sphingomyelinase (MA-nSMase), the mammalian sphingomyelin phosphodiesterase 5 |
| Q24632632 | In vivo delivery of FTY720 prevents radiation-induced ovarian failure and infertility in adult female nonhuman primates |
| Q44697049 | Increased radiation sensitivity of head and neck squamous cell carcinoma with sphingosine kinase 1 inhibition. |
| Q34276549 | Inhibition of ceramide biosynthesis preserves photoreceptor structure and function in a mouse model of retinitis pigmentosa. |
| Q90418460 | Intricate role of mitochondrial lipid in mitophagy and mitochondrial apoptosis: its implication in cancer therapeutics |
| Q39347185 | Ionizing radiations increase the activity of the cell surface glycohydrolases and the plasma membrane ceramide content. |
| Q47696246 | Lipid and Carbohydrate Metabolism in Caenorhabditis elegans |
| Q47615458 | Lipotoxic very-long-chain ceramides cause mitochondrial dysfunction, oxidative stress, and cell death in cardiomyocytes |
| Q36534308 | Localized sphingolipid signaling at presynaptic terminals is regulated by calcium influx and promotes recruitment of priming factors |
| Q41952712 | Loss of Sphingosine Kinase Alters Life History Traits and Locomotor Function in Caenorhabditis elegans |
| Q35149996 | Many ceramides. |
| Q34330398 | Membranes in balance: mechanisms of sphingolipid homeostasis |
| Q33939529 | Mitochondrial ceramide-rich macrodomains functionalize Bax upon irradiation |
| Q90172536 | Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress |
| Q47133063 | Monitoring Changes in the Oligomeric State of a Candidate Endoplasmic Reticulum (ER) Ceramide Sensor by Single-molecule Photobleaching |
| Q92092802 | Monte-Carlo dosimetry and real-time imaging of targeted irradiation consequences in 2-cell stage Caenorhabditis elegans embryo |
| Q97643468 | NFYB-1 regulates mitochondrial function and longevity via lysosomal prosaposin |
| Q98664985 | NRIP3 upregulation confers resistance to chemoradiotherapy in ESCC via RTF2 removal by accelerating ubiquitination and degradation of RTF2 |
| Q37682750 | Non-apoptotic cell death in Caenorhabditis elegans |
| Q33877282 | Novel Mutations in Synaptic Transmission Genes Suppress Neuronal Hyperexcitation in Caenorhabditis elegans |
| Q35107592 | Novel pathway of ceramide production in mitochondria: thioesterase and neutral ceramidase produce ceramide from sphingosine and acyl-CoA. |
| Q37005492 | Off-target function of the Sonic hedgehog inhibitor cyclopamine in mediating apoptosis via nitric oxide-dependent neutral sphingomyelinase 2/ceramide induction |
| Q34921734 | Oxidized phospholipids induce ceramide accumulation in RAW 264.7 macrophages: role of ceramide synthases |
| Q28751278 | Phylogeny and function of the invertebrate p53 superfamily |
| Q48768250 | Principles of radiobiology of stereotactic radiosurgery and clinical applications in the central nervous system. |
| Q37090144 | Pro-crossover factors regulate damage-dependent apoptosis in the Caenorhabditis elegans germ line |
| Q92659591 | Probiotic Bacillus subtilis Protects against α-Synuclein Aggregation in C. elegans |
| Q90010298 | Prokaryotic and Mitochondrial Lipids: A Survey of Evolutionary Origins |
| Q39088175 | Radiation-induced acid ceramidase confers prostate cancer resistance and tumor relapse |
| Q35988918 | Recruitment of sphingosine kinase to presynaptic terminals by a conserved muscarinic signaling pathway promotes neurotransmitter release |
| Q37262173 | Regulation of ceramide generation during macrophage apoptosis by ASMase and de novo synthesis |
| Q35633868 | Regulation of ceramide synthase-mediated crypt epithelium apoptosis by DNA damage repair enzymes |
| Q35223807 | Results of a phase II trial of gemcitabine plus doxorubicin in patients with recurrent head and neck cancers: serum C₁₈-ceramide as a novel biomarker for monitoring response |
| Q27319572 | Ribosome synthesis and MAPK activity modulate ionizing radiation-induced germ cell apoptosis in Caenorhabditis elegans |
| Q35225101 | Role of sphingolipids in murine radiation-induced lung injury: protection by sphingosine 1-phosphate analogs |
| Q36489335 | SIRT3 Deacetylates Ceramide Synthases: IMPLICATIONS FOR MITOCHONDRIAL DYSFUNCTION AND BRAIN INJURY. |
| Q41612718 | Spatial function of the oxidative DNA damage response in radiation induced bystander effects in intra- and inter-system of Caenorhabditis elegans |
| Q36422392 | Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis |
| Q49950035 | Sphingolipid metabolism in cancer signalling and therapy. |
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| Q38809404 | Sphingolipids in mitochondria. |
| Q48154081 | Starvation-Induced Stress Response Is Critically Impacted by Ceramide Levels in Caenorhabditis elegans |
| Q57179631 | Structure and conserved function of iso-branched sphingoid bases from the nematode |
| Q28474884 | The Caenorhabditis elegans homolog of Gen1/Yen1 resolvases links DNA damage signaling to DNA double-strand break repair |
| Q36602674 | The role of mitochondria in apoptosis*. |
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