Adenylate kinase and AMP signaling networks: metabolic monitoring, signal communication and body energy sensing

scientific article

Adenylate kinase and AMP signaling networks: metabolic monitoring, signal communication and body energy sensing is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.3390/IJMS10041729
P3181OpenCitations bibliographic resource ID3805720
P932PMC publication ID2680645
P698PubMed publication ID19468337
P5875ResearchGate publication ID26239857

P2093author name stringAndre Terzic
Petras Dzeja
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Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathyQ24292259
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylaseQ24299948
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinaseQ24309462
Nicardipine and adenosine "flush cocktail" to prevent no-reflow during rotational atherectomyQ46311656
In situ compartmentation of creatine kinase in intact sarcomeric muscle: the acto-myosin overlap zone as a molecular sieveQ46370911
Adenosine mediation of presynaptic feedback inhibition of glutamate releaseQ46453275
Adenylate kinase of Escherichia coli, a component of the phage T4 dNTP synthetase complexQ46533107
5-aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis.Q46561933
Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activityQ46606786
Constant darkness is a mammalian biological signalQ46639456
A sea urchin sperm flagellar adenylate kinase with triplicated catalytic domainsQ46665496
Structural and functional changes in heart mitochondria from sucrose-fed hypertriglyceridemic rats.Q46684528
Characterizing the lipid-lowering effects and antioxidant mechanisms of tomato pasteQ46715991
Contraction-mediated phosphorylation of AMPK is lower in skeletal muscle of adenylate kinase-deficient miceQ46728828
ADP-regenerating enzyme systems in mitochondria of guinea pig myometrium and heartQ46730574
Rosiglitazone stimulates nitric oxide synthesis in human aortic endothelial cells via AMP-activated protein kinase.Q46731659
Seminal plasma proteins regulate the association of lipids and proteins within detergent-resistant membrane domains of bovine spermatozoaQ46782024
Bioenergetic protection of failing atrial and ventricular myocardium by vasopeptidase inhibitor omapatrilatQ46844264
Opposite pathobiochemical fate of pyruvate kinase and adenylate kinase in aged rat skeletal muscle as revealed by proteomic DIGE analysisQ46873515
Constant darkness is a circadian metabolic signal in mammalsQ46900386
Differentially expressed genes in adipose tissues of high body weight-selected (obese) and unselected (lean) mouse linesQ47288794
Regulation of Mre11/Rad50 by Nbs1: effects on nucleotide-dependent DNA binding and association with ataxia-telangiectasia-like disorder mutant complexes.Q47635097
Mitochondrial energy metabolism in the left ventricular tissue of spontaneously hypertensive rats: abnormalities in both adeninenucleotide and phosphate translocators and enzyme adenylate-kinase and creatine-phosphokinase activitiesQ48031539
Identification of hypoxically inducible mRNAs in HeLa cells using differential-display PCR. Role of hypoxia-inducible factor-1.Q48058964
Neurotrophins, growth-factor-regulated genes and the control of energy balanceQ48365599
Peripherally administered desacetyl alpha-MSH and alpha-MSH both influence postnatal rat growth and associated rat hypothalamic protein expression.Q48462740
Relationship of ATP:AMP phosphotransferase isozymes to tissue respirationQ48826850
Release of adenylate kinase into cerebrospinal fluid during open-heart surgery and its relation to postoperative intellectual functionQ48943339
Characterization of hCINAP, a novel coilin-interacting protein encoded by a transcript from the transcription factor TAFIID32 locusQ24312861
Cloning and expression of human adenylate kinase 2 isozymes: differential expression of adenylate kinase 1 and 2 in human muscle tissuesQ24317549
The crystal structure of human adenylate kinase 6: An adenylate kinase localized to the cell nucleusQ24337291
Deficiency of a plastidial adenylate kinase in Arabidopsis results in elevated photosynthetic amino acid biosynthesis and enhanced growthQ24556656
Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complexQ24604459
Defective metabolic signaling in adenylate kinase AK1 gene knock-out hearts compromises post-ischemic coronary reflowQ24631754
Blocking taste receptor activation of gustducin inhibits gustatory responses to bitter compoundsQ24653917
Human adenylate kinase 2 deficiency causes a profound hematopoietic defect associated with sensorineural deafnessQ24655619
Fructose-induced leptin resistance exacerbates weight gain in response to subsequent high-fat feedingQ24656064
Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injuryQ24657261
Traditional chinese medicine in treatment of metabolic syndromeQ24657961
AMP-activated protein kinase mediates carotid body excitation by hypoxiaQ24676114
ABCC9 mutations identified in human dilated cardiomyopathy disrupt catalytic KATP channel gatingQ24680296
Gene expression profiling of tumours derived from rasV12/E1A-transformed mouse embryonic fibroblasts to identify genes required for tumour developmentQ24795128
Creatine kinase-mediated ATP supply fuels actin-based events in phagocytosisQ27333700
Structure, catalysis and supramolecular assembly of adenylate kinase from maizeQ27748782
Resveratrol improves health and survival of mice on a high-calorie dietQ27860950
The essential protein fap7 is involved in the oxidative stress response of Saccharomyces cerevisiaeQ27931493
Rad50 adenylate kinase activity regulates DNA tethering by Mre11/Rad50 complexesQ27933110
Yeast adenylate kinase is active simultaneously in mitochondria and cytoplasm and is required for non-fermentative growthQ27940096
Myristoylated adenylate kinase-2 of Plasmodium falciparum forms a heterodimer with myristoyltransferaseQ27973663
HIF-1 and human disease: one highly involved factorQ28144179
Subcellular targeting of metabolic enzymes to titin in heart muscle may be mediated by DRAL/FHL-2Q28214815
mTOR integrates amino acid- and energy-sensing pathwaysQ28235076
The AMP-activated protein kinase cascade--a unifying system for energy controlQ28239257
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamusQ28254114
Identification of a novel adenylate kinase system in the brain: cloning of the fourth adenylate kinaseQ28288727
Location and properties of two isoenzymes of cardiac adenylate kinaseQ28366174
The energy hypothesis of sleep revisitedQ28383752
Tissue-specific and developmentally regulated expression of the genes encoding adenylate kinase isozymesQ28567273
Distribution and developmental changes of adenylate kinase isozymes in the rat brain: localization of adenylate kinase 1 in the olfactory bulbQ28571783
Combined cDNA array/RT-PCR analysis of gene expression profile in rat gastrocnemius muscle: relation to its adaptive function in energy metabolism during fastingQ28574809
Skeletal muscle contractile performance and ADP accumulation in adenylate kinase-deficient miceQ45230695
Smoking and human reproduction: the effect of adenylate kinase genetic polymorphismQ45790285
Human cytosolic adenylate kinase allelozymes; purification and characterization.Q45881767
Trypanosoma cruzi: multiple nucleoside diphosphate kinase isoforms in a single cell.Q45900614
Sphingosine-1-phosphate receptors stimulate macrophage plasma-membrane actin assembly via ADP release, ATP synthesis and P2X7R activationQ46143632
Statins activate AMP-activated protein kinase in vitro and in vivoQ46230916
Metabolic monitoring by bacterial mRNAsQ36063382
Adenine nucleoside diphosphates block adaptation of mechanoelectrical transduction in hair cellsQ36194331
AMP-activated protein kinase: a key stress signaling pathway in the heartQ36205350
Fuel sensing and the central nervous system (CNS): implications for the regulation of energy balance and the treatment for obesityQ36207964
Dynamics of nucleotide metabolism as a supporter of life phenomenaQ36259289
Adenylate kinase phosphotransfer communicates cellular energetic signals to ATP-sensitive potassium channelsQ36319041
Glycolysis and sperm motility: does a spoonful of sugar help the flagellum go round?Q36366170
Cardiac system bioenergetics: metabolic basis of the Frank-Starling law.Q36367258
AMPK alterations in cardiac physiology and pathology: enemy or ally?Q36475855
AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissuesQ36482341
The role of AMP-activated protein kinase in mitochondrial biogenesisQ36482349
Metabolic sensing neurons and the control of energy homeostasisQ36561276
Systems biology approaches to metabolic and cardiovascular disorders: network perspectives of cardiovascular metabolismQ36583266
Ecto-5' nucleotidase (CD73)-mediated adenosine generation and signaling in murine cardiac allograft vasculopathyQ36818237
Differential effects of central fructose and glucose on hypothalamic malonyl-CoA and food intake.Q36964213
Role of CFTR's intrinsic adenylate kinase activity in gating of the Cl(-) channel.Q36983790
AMPK/LKB1 signaling in epithelial cell polarity and cell divisionQ36994994
Biochemical topology: From vectorial metabolism to morphogenesisQ37072406
Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways?Q37086284
Regulation of food intake through hypothalamic signaling networks involving mTOR.Q37144986
Enzymatically inactive adenylate kinase 4 interacts with mitochondrial ADP/ATP translocaseQ37177317
Endocrine and metabolic effects of consuming fructose- and glucose-sweetened beverages with meals in obese men and women: influence of insulin resistance on plasma triglyceride responses.Q37198051
The regulation of AMP-activated protein kinase by upstream kinases.Q37249352
AMPK: a key regulator of energy balance in the single cell and the whole organism.Q37249357
Activation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failureQ37259538
AMP-activated protein kinase promotes the differentiation of endothelial progenitor cellsQ37332718
Mapping hypoxia-induced bioenergetic rearrangements and metabolic signaling by 18O-assisted 31P NMR and 1H NMR spectroscopyQ37346693
Nucleotide-gated KATP channels integrated with creatine and adenylate kinases: amplification, tuning and sensing of energetic signals in the compartmentalized cellular environmentQ37383374
The glycogen-binding domain on the AMPK beta subunit allows the kinase to act as a glycogen sensor.Q38357762
Effect of acute and chronic ethanol administration on the content of coenzymes linked to energy transfer in the liver of rats fed standard or low-protein dietQ39252393
Identification of genes that regulate epithelial cell migration using an siRNA screening approachQ39892281
Modulation of cell motility by spatial repositioning of enzymatic ATP/ADP exchange capacityQ39917139
Cytosolic adenylate kinases regulate K-ATP channel activity in human beta-cellsQ40017600
Identification of poly(ADP-ribose) polymerase-1 as the OXPHOS-generated ATP sensor of nuclei of animal cellsQ40036767
AMPK expression and phosphorylation are increased in rodent muscle after chronic leptin treatmentQ78542116
Keystone meeting summary: 'Adipogenesis, obesity, and inflammation' and 'Diabetes mellitus and the control of cellular energy metabolism, ' January 21-26, 2006, Vancouver, CanadaQ80122450
An adenylate kinase is involved in KATP channel regulation of mouse pancreatic beta cellsQ80808981
Ectoadenylate kinase and plasma membrane ATP synthase activities of human vascular endothelial cellsQ83818344
Fatty acids attenuate insulin regulation of 5'-AMP-activated protein kinase and insulin cardioprotection after ischemiaQ83896546
Increase of adenylate kinase isozyme 1 protein during neuronal differentiation in mouse embryonal carcinoma P19 cells and in rat brain primary cultured cellsQ28579228
Mutation of murine adenylate kinase 7 underlies a primary ciliary dyskinesia phenotype.Q28586510
Cellular distribution and developmental expression of AMP-activated protein kinase isoforms in mouse central nervous systemQ28587570
Adenylate kinases 1 and 2 are part of the accessory structures in the mouse sperm flagellumQ28590302
wt p53 dependent expression of a membrane-associated isoform of adenylate kinaseQ28594646
Regulation of cyclic GMP metabolism in toad photoreceptors. Definition of the metabolic events subserving photoexcited and attenuated statesQ28609964
Creatine kinase activity is associated with blood pressureQ29353962
Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chainQ29615210
Biochemical characterization of recombinant hepatitis C virus nonstructural protein 4B: evidence for ATP/GTP hydrolysis and adenylate kinase activity.Q30374365
Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storageQ30445033
Hair bundles are specialized for ATP delivery via creatine kinase.Q30479206
Succinate receptor GPR91 provides a direct link between high glucose levels and renin release in murine and rabbit kidneyQ30482204
Identification of proteins undergoing glutathionylation in oxidatively stressed hepatocytes and hepatoma cellsQ30966258
Proteomic analysis of mdx skeletal muscle: Great reduction of adenylate kinase 1 expression and enzymatic activityQ31027117
Proteome analysis of skeletal muscle from obese and morbidly obese womenQ31163988
Extracellular ATP formation on vascular endothelial cells is mediated by ecto-nucleotide kinase activities via phosphotransfer reactions.Q31812403
Identification of novel lung genes in bronchial epithelium by serial analysis of gene expressionQ33248424
Adenylate kinase 5 autoimmunity in treatment refractory limbic encephalitisQ33282954
Nucleoside monophosphate kinases: structure, mechanism, and substrate specificityQ33602275
Developmental restructuring of the creatine kinase system integrates mitochondrial energetics with stem cell cardiogenesisQ33721600
Dietary nucleotides: effects on the immune and gastrointestinal systems.Q33777620
Energy as a constraint on the coding and processing of sensory informationQ33954048
Adenosine in the central nervous system: release mechanisms and extracellular concentrationsQ33955930
Saliva of the Yellow Fever mosquito, Aedes aegypti, modulates murine lymphocyte functionQ33983036
Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease.Q34007373
Failing energetics in failing heartsQ34027497
Energetic communication between mitochondria and nucleus directed by catalyzed phosphotransfer.Q34099463
Structural features of metabolite-sensing riboswitchesQ34105926
Reversal of thrombin-induced deactivation of CD39/ATPDase in endothelial cells by HMG-CoA reductase inhibition: effects on Rho-GTPase and adenosine nucleotide metabolism.Q34133687
Adenylate kinase 1 deficiency induces molecular and structural adaptations to support muscle energy metabolismQ34174404
Cellular characterization of adenylate kinase and its isoform: two-photon excitation fluorescence imaging and fluorescence correlation spectroscopyQ34179358
Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR functionQ34194696
Oda5p, a novel axonemal protein required for assembly of the outer dynein arm and an associated adenylate kinaseQ34359240
Adenosine deaminase deficiency: metabolic basis of immune deficiency and pulmonary inflammationQ34393135
Severe erythrocyte adenylate kinase deficiency due to homozygous A-->G substitution at codon 164 of human AK1 gene associated with chronic haemolytic anaemiaQ34452591
Roles of static and dynamic domains in stability and catalysis of adenylate kinaseQ34478954
Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1alpha) and HIF-2alpha in stem cellsQ34564866
Adenosinergic cardioprotection: multiple receptors, multiple pathwaysQ34615807
Erythrocyte adenylate kinase deficiency: characterization of recombinant mutant forms and relationship with nonspherocytic hemolytic anemia.Q34657517
Brain glucose sensing, counterregulation, and energy homeostasisQ34663563
Adenylate kinase 1 gene deletion disrupts muscle energetic economy despite metabolic rearrangementQ34682618
UCP2 and UCP3 in muscle controlling body metabolismQ34731848
Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2.Q34891147
A molecular approach to the concerted action of kinases involved in energy homoeostasisQ35053007
Phosphotransfer networks and cellular energeticsQ35131166
Creatine kinase, an ATP-generating enzyme, is required for thrombin receptor signaling to the cytoskeletonQ35375897
On the role of organized multienzyme systems in cellular metabolism: a general synthesisQ35529887
Mitochondrial oxidative metabolism is required for the cardiac differentiation of stem cellsQ35596393
Prevention of fructose-induced hypertension by dietary vitaminsQ35607761
Myosin-dependent transport in neuronsQ35620185
Resveratrol stimulates AMP kinase activity in neuronsQ35758555
A renaissance of metabolite sensing and signaling: from modular domains to riboswitchesQ35877045
Transgenesis and cardiac energetics: new insights into cardiac metabolismQ35879480
The role of endogenous and exogenous AMP in asthma and chronic obstructive pulmonary disease.Q35916249
The AMP-activated protein kinase pathway--new players upstream and downstream.Q35930365
Metabolic regulation of the pancreatic beta-cell ATP-sensitive K+ channel: a pas de deuxQ35961940
Roles of ATP-sensitive K+ channels as metabolic sensors: studies of Kir6.x null miceQ35961964
A novel nuclear-localized protein with special adenylate kinase properties from Caenorhabditis elegans.Q51178811
Adenylate kinase activity in rat liver.Q51193400
Cytoplasmic and mitochondrial forms of yeast adenylate kinase 2 are N-acetylated.Q52519603
Cytosolic adenylates and adenosine release in perfused working heart. Comparison of whole tissue with cytosolic non-aqueous fractionation analyses.Q53887285
An expanded adenylate kinase gene family in the protozoan parasite Trypanosoma cruzi.Q54468113
Identification of unique gene expression patterns within different lesional sites of keloids.Q54546049
Improved glucose homeostasis in mice overexpressing human UCP3: a role for AMP-kinase?Q55162970
Role of energy charge and AMP-activated protein kinase in adipocytes in the control of body fat storesQ60449199
The suppressor of cytokine signaling 3 inhibits leptin activation of AMP-kinase in cultured skeletal muscle of obese humansQ64377667
32P-incorporation in adenosine phosphates of the rat brain after oral application of vincamine for 2 weeks (author's transl)Q67028461
The role of adenylate kinase in dynamic compartmentation of adenine nucleotides in the mitochondrial intermembrane spaceQ68078984
Rat brain synaptosomal ATP:AMP-phosphotransferase activityQ69355052
Interaction of immobilized phosphofructokinase with soluble muscle proteinsQ69992584
Analysis of the effects of ethanol, fructose and nicotinamide on the free nucleotides of rat liver using high performance liquid chromatographyQ70042734
The effect of adenylate kinase activity on the rate and efficiency of energy transport from mitochondria to hexokinaseQ70084875
Myokinase and contractile function of glycerinated muscle fibersQ70139611
Structural relationships in the adenylate kinase familyQ70153716
Functional coupling of creatine phosphokinase and adenylate kinase with adenine nucleotide translocase and its role in regulation of heart mitochondrial respirationQ70168346
Traveling NADH and proton waves during oscillatory glycolysis in vitroQ70889932
Anti-lymphoproliferative activity of brown adipose tissue of hibernating ground squirrels is mainly caused by AMPQ70907924
Suppression of creatine kinase-catalyzed phosphotransfer results in increased phosphoryl transfer by adenylate kinase in intact skeletal muscleQ71143003
Adenylate kinase-catalyzed phosphoryl transfer couples ATP utilization with its generation by glycolysis in intact muscleQ72132147
High-level ATP production by a genetically-engineered Candida yeastQ72272478
Congenital haemolytic anaemia associated with adenylate kinase deficiencyQ72772375
Ultrastructural localization of 5'AMP odorant receptor sites on the dendrites of olfactory receptor neurons of the spiny lobsterQ72831420
Compromised energetics in the adenylate kinase AK1 gene knockout heart under metabolic stressQ73006671
Enzyme adaptations of human skeletal muscle during bicycle short-sprint training and detrainingQ74043179
A case of complete adenylate kinase deficiency due to a nonsense mutation in AK-1 gene (Arg 107 --> Stop, CGA --> TGA) associated with chronic haemolytic anaemiaQ77418362
Extracellular adenosine levels and cellular energy metabolism in ischemically preconditioned rat heartQ77755928
Adenylate kinase-catalyzed phosphotransfer in the myocardium : increased contribution in heart failureQ77807877
AK2 activates a novel apoptotic pathway through formation of a complex with FADD and caspase-10.Q40064206
The role of adenosine in the regulation of coronary blood flowQ40122505
Energy-dependent regulation of cell structure by AMP-activated protein kinaseQ40135869
Cell surface adenylate kinase activity regulates the F(1)-ATPase/P2Y (13)-mediated HDL endocytosis pathway on human hepatocytes.Q40208744
Mitochondrial GTP-AMP Phosphotransferase. 1. Purification and PropertiesQ40216561
Probing the human kinome for kinases involved in pancreatic cancer cell survival and gemcitabine resistanceQ40225449
Extracellular adenosine activates AMP-dependent protein kinase (AMPK).Q40298857
Mimicry of a cellular low energy status blocks tumor cell anabolism and suppresses the malignant phenotypeQ40444041
Proteome characterization of human NK-92 cells identifies novel IFN-alpha and IL-15 target genes.Q40459482
Interaction of creatine kinase and adenylate kinase systems in muscle cellsQ40561393
Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretionQ40590712
The fate of P2Y-related orphan receptors: GPR80/99 and GPR91 are receptors of dicarboxylic acidsQ40723680
Energy metabolism of the heart: from basic concepts to clinical applicationsQ40748839
New strategies for intraoperative myocardial protection.Q40952987
Adenylate kinase: kinetic behavior in intact cells indicates it is integral to multiple cellular processesQ41007419
Smart hydrogels containing adenylate kinase: translating substrate recognition into macroscopic motionQ41058344
Evidence that AMP triggers phosphorylation as well as direct allosteric activation of rat liver AMP-activated protein kinase. A sensitive mechanism to protect the cell against ATP depletionQ41134802
Suppression of adenylate kinase catalyzed phosphotransfer precedes and is associated with glucose-induced insulin secretion in intact HIT-T15 cellsQ41185254
Relationship between bacterial virulence and nucleotide metabolism: a mutation in the adenylate kinase gene renders Yersinia pestis avirulentQ41466163
The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegansQ41711470
Phosphotransfer reactions in the regulation of ATP-sensitive K+ channelsQ41759438
Spatial patterning of metabolism by mitochondria, oxygen, and energy sinks in a model cytoplasmQ41808588
AMP decreases the efficiency of skeletal-muscle mitochondriaQ41842749
Mechanistic insight into control of CFTR by AMPK.Q41856265
The forkhead protein Foxj1 specifies node-like cilia in Xenopus and zebrafish embryosQ42158837
"AMPing up" our understanding of the hypothalamic control of energy balanceQ42430520
Evidence for compartmentalized adenylate kinase catalysis serving a high energy phosphoryl transfer function in rat skeletal muscleQ42479216
Control and function of the homeostatic sleep response by adenosine A1 receptorsQ42573867
Thiazolidinediones can rapidly activate AMP-activated protein kinase in mammalian tissuesQ42805365
Metabolic analysis of senescent human fibroblasts reveals a role for AMP in cellular senescenceQ43003291
5'-Nucleotidase activity and adenosine production in rat liver mitochondriaQ43457993
Directed inhibition of nuclear import in cellular hypertrophy.Q43562703
Changes in glycolytic network and mitochondrial design in creatine kinase-deficient musclesQ43700616
Cellular energetics in the preconditioned state: protective role for phosphotransfer reactions captured by 18O-assisted 31P NMR.Q43754765
The relationship between AMP-activated protein kinase activity and AMP concentration in the isolated perfused rat heartQ43798557
Acute alcohol-induced protection against infarction in rabbit hearts: differences from and similarities to ischemic preconditioningQ43799546
Liver Adenine Nucleotides: Fructose-Induced Depletion and Its Effect on Protein SynthesisQ43848070
Adenylate kinase activity in ejaculated bovine sperm flagella.Q43942174
Coupling of cell energetics with membrane metabolic sensing. Integrative signaling through creatine kinase phosphotransfer disrupted by M-CK gene knock-outQ43967743
A potential role for AMP-activated protein kinase in meiotic induction in mouse oocytes.Q43968526
Metformin improves cardiac functional recovery after ischemia in ratsQ43978119
Adenylate kinase AK1 knockout heart: energetics and functional performance under ischemia-reperfusionQ44068514
Starch content and yield increase as a result of altering adenylate pools in transgenic plantsQ44212617
Actin-ATP hydrolysis is a major energy drain for neurons.Q44270163
Physiological modulation of CFTR activity by AMP-activated protein kinase in polarized T84 cellsQ44273159
Human airway ecto-adenylate kinase. A mechanism to propagate ATP signaling on airway surfacesQ44292829
Failing atrial myocardium: energetic deficits accompany structural remodeling and electrical instabilityQ44355163
Measurement of adenine nucleotides in plasmaQ44407428
Paradoxical absence of M lines and downregulation of creatine kinase in mouse extraocular muscleQ44418910
Impaired Intracellular Energetic Communication in Muscles from Creatine Kinase and Adenylate Kinase (M-CK/AK1) Double Knock-out MiceQ44429281
Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cellsQ44468960
Adenylate metabolism and adenosine formation in the heartQ44506121
Akt activity negatively regulates phosphorylation of AMP-activated protein kinase in the heartQ44532391
Fructose-Fed Rats Are Protected against Ischemia/Reperfusion InjuryQ44611077
Adenosine Biosynthesis in the Collecting DuctQ44618371
Phosphotransfer dynamics in skeletal muscle from creatine kinase gene-deleted miceQ44772222
Two structurally distinct and spatially compartmentalized adenylate kinases are expressed from the AK1 gene in mouse brainQ44772226
Proteomic characterization of isolated retinal pigment epithelium microvilliQ45059134
Metabolic activation of AMP kinase in vascular smooth muscleQ45065640
Intracellular positioning of isoforms explains an unusually large adenylate kinase gene family in the parasite Trypanosoma bruceiQ45228963
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectcatalysisQ82264
heterocyclic compoundQ193430
organic chemistryQ11351
enzymeQ8047
nucleotideQ28745
P304page(s)1729-72
P577publication date2009-04-01
2009-04-17
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleAdenylate kinase and AMP signaling networks: metabolic monitoring, signal communication and body energy sensing
P478volume10

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Q34343389High-energy phosphotransfer in the failing mouse heart: role of adenylate kinase and glycolytic enzymes.
Q92661966Host-Induced Gene Silencing of an Adenylate Kinase Gene Involved in Fungal Energy Metabolism Improves Plant Resistance to Verticillium dahliae
Q34625120Hypoxia impacts large adults first: consequences in a warming world
Q48046169Ichthyophthirius multifiliis impairs splenic enzymes of the phosphoryl transfer network in naturally infected Rhamdia quelen: effects on energetic homeostasis
Q34605857Identification and biochemical characterization of adenylate kinase 1 from Clonorchis sinensis
Q41923686Identification of direct and indirect effectors of the transient receptor potential melastatin 2 (TRPM2) cation channel.
Q91785346Identification of time‑series differentially expressed genes and pathways associated with heart failure post‑myocardial infarction using integrated bioinformatics analysis
Q43300796Identification of two active functional domains of human adenylate kinase 5.
Q40233001Immunization with recombinant schistosome adenylate kinase 1 partially protects mice against Schistosoma japonicum infection
Q47620233Impact of cellular health conditions on the protein folding state in mammalian cells.
Q38235840Inborn errors of metabolism underlying primary immunodeficiencies
Q47850851Inorganic polyphosphate induces accelerated tube formation of HUVEC endothelial cells.
Q41200478Intermittent hypoxic training improves anaerobic performance in competitive swimmers when implemented into a direct competition mesocycle.
Q59138361Intracellular Energy-Transfer Networks and High-Resolution Respirometry: A Convenient Approach for Studying Their Function
Q42868512K(ATP) channels process nucleotide signals in muscle thermogenic response
Q57289904Kinematic Flexibility Analysis: Hydrogen Bonding Patterns Impart a Spatial Hierarchy of Protein Motion
Q35221451LKB1/Mo25/STRAD uniquely impacts sarcomeric contractile function and posttranslational modification
Q36984254Liver Kinase B1 complex acts as a novel modifier of myofilament function and localizes to the Z-disk in cardiac myocytes
Q36295808Long-Term survival of anoxia despite rapid ATP decline in embryos of the annual killifish Austrofundulus limnaeus
Q36249105MAPRE1 as a plasma biomarker for early-stage colorectal cancer and adenomas
Q38678819Magnetic resonance imaging and spectroscopy for differential assessment of liver abnormalities induced by Opisthorchis felineus in an animal model
Q47110867Metabolic remodeling in human colorectal cancer and surrounding tissues: alterations in regulation of mitochondrial respiration and metabolic fluxes
Q42912497Metabolic responses to a 48-h ultra-marathon run in middle-aged male amateur runners.
Q38938409Metabolomic analysis of human oral cancer cells with adenylate kinase 2 or phosphorylate glycerol kinase 1 inhibition
Q84346444Modulation of the hepatocyte rough endoplasmic reticulum single chloride channel by nucleotide-Mg2+ interaction
Q34587047Molecular and functional characterization of a Trypanosoma cruzi nuclear adenylate kinase isoform
Q42636986Molecular system bioenergetics-new aspects of metabolic research
Q64110277Neural control of body-plan axis in regenerating planaria
Q39379407Neuropathogenic role of adenylate kinase-1 in Aβ-mediated tau phosphorylation via AMPK and GSK3β.
Q34510544New crystal structures of adenylate kinase from Streptococcus pneumoniae D39 in two conformations
Q41136916New insights on the regulation of the adenine nucleotide pool of erythrocytes in mouse models
Q42794657On energy circuits in the failing myocardium
Q35130577Oral cancer cells may rewire alternative metabolic pathways to survive from siRNA silencing of metabolic enzymes
Q37620415Pharmacogenomic Characterization and Isobologram Analysis of the Combination of Ascorbic Acid and Curcumin-Two Main Metabolites of Curcuma longa-in Cancer Cells.
Q47948078Polyphosphate as a donor of high-energy phosphate for the synthesis of ADP and ATP.
Q91525559Prognostic and therapeutic potential of Adenylate kinase 2 in lung adenocarcinoma
Q36530448Proliferation of Human Primary Myoblasts Is Associated with Altered Energy Metabolism in Dependence on Ageing In Vivo and In Vitro
Q92247432Protein Changes in Response to Lead Stress of Lead-Tolerant and Lead-Sensitive Industrial Hemp Using SWATH Technology
Q48371760Purine metabolism gene deregulation in Parkinson's disease
Q101237389Qualitative and quantitative differences in endometrial inflammatory gene expression precede the development of bovine uterine disease
Q39289613Rearrangement of energetic and substrate utilization networks compensate for chronic myocardial creatine kinase deficiency
Q34087645Reduced coupling of oxidative phosphorylation in vivo precedes electron transport chain defects due to mild oxidative stress in mice
Q35894385Reticular dysgenesis-associated AK2 protects hematopoietic stem and progenitor cell development from oxidative stress
Q36269062Review of the neuroanatomic landscape implicated in glucose sensing and regulation of nutrient signaling: immunophenotypic localization of diabetes gene Tcf7l2 in the developing murine brain
Q38559463Severe combined immunodeficiency--an update.
Q38730752Simple oxygraphic analysis for the presence of adenylate kinase 1 and 2 in normal and tumor cells.
Q42731964Singular features of trypanosomatids' phosphotransferases involved in cell energy management
Q89602293Snellenius manilae bracovirus suppresses the host immune system by regulating extracellular adenosine levels in Spodoptera litura
Q64232571Soluble and membrane-bound adenylate kinase and nucleotidases augment ATP-mediated inflammation in diabetic retinopathy eyes with vitreous hemorrhage
Q92837739Sputum metabolomic profiling of bronchial asthma based on quadruple time-of-flight mass spectrometry
Q27972936Subcellular localization of adenylate kinases in Plasmodium falciparum
Q43178374Substrate Binding Specifically Modulates Domain Arrangements in Adenylate Kinase
Q28547854Synergistic Effect of Oleanolic Acid on Aminoglycoside Antibiotics against Acinetobacter baumannii
Q37628292The DUSP26 phosphatase activator adenylate kinase 2 regulates FADD phosphorylation and cell growth
Q39122685The HIF-1 transcription complex is essential for translational control of myeloid hematopoietic cell function by maintaining mTOR phosphorylation.
Q28385023The cellular and compartmental profile of mouse retinal glycolysis, tricarboxylic acid cycle, oxidative phosphorylation, and ~P transferring kinases
Q24307438The characterization of human adenylate kinases 7 and 8 demonstrates differences in kinetic parameters and structural organization among the family of adenylate kinase isoenzymes
Q50585293The effect of genetic variability on the correlation between blood glucose and glycated hemoglobin levels.
Q24317654The human adenylate kinase 9 is a nucleoside mono- and diphosphate kinase
Q54986468Thiol/disulfide status regulates the activity of thiol-containing kinases related to energy homeostasis in rat kidney.
Q50930133Transcriptome analysis of cytoplasmic male sterility and restoration in CMS-D8 cotton.
Q88590376Translational regulation by miR-301b upregulates AMP deaminase in diabetic hearts
Q30248230Treatment of nonalcoholic fatty liver disease: role of AMPK.
Q48670285Tyrosine impairs enzymes of energy metabolism in cerebral cortex of rats
Q47172748Uptake of polyphosphate microparticles in vitro (SaOS-2 and HUVEC cells) followed by an increase of the intracellular ATP pool size
Q47787124Water content, adenylate kinase, and mitochondria drive adenylate balance in dehydrating and imbibing seeds

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