Tumor necrosis factor receptor-associated factor 6 is an intranuclear transcriptional coactivator in osteoclasts

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Tumor necrosis factor receptor-associated factor 6 is an intranuclear transcriptional coactivator in osteoclasts is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M802525200
P932PMC publication ID2662164
P698PubMed publication ID18768464

P50authorSteven L. TeitelbaumQ42404516
P2093author name stringJikun Zha
Haibo Zhao
F Patrick Ross
Shuting Bai
P2860cites workDe-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signallingQ24299573
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activationQ24311588
Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activationQ24321363
The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytesQ24338639
TRAF6-mediated ubiquitination regulates nuclear translocation of NRIF, the p75 receptor interactorQ27919684
Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient miceQ28140546
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chainQ28142613
Identification of the LIM protein FHL2 as a coactivator of beta-cateninQ28216665
Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrenceQ28277232
Proline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor enhances androgen receptor functions through LIM-only coactivator, four-and-a-half LIM-only protein 2Q28280935
The LIM protein, Limd1, regulates AP-1 activation through an interaction with Traf6 to influence osteoclast developmentQ28512132
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signalingQ28513445
FHL2 inhibits the activated osteoclast in a TRAF6-dependent mannerQ34014506
TRAF6, a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology.Q34272380
The multifunctional roles of the four-and-a-half-LIM only protein FHL2.Q34481193
Proteasome-dependent down-regulation of activated Stat5A in the nucleusQ35848923
Normal and transforming functions of RUNX1: a perspectiveQ36297312
The molecular understanding of osteoclast differentiationQ36650749
Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1)Q36671577
TNF-alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligandQ37413745
Lysine 63 polyubiquitination of the nerve growth factor receptor TrkA directs internalization and signalingQ40358414
Interaction and functional cooperation between the LIM protein FHL2, CBP/p300, and beta-cateninQ40486121
IL-3 expression by myeloma cells increases both osteoclast formation and growth of myeloma cellsQ40616669
IL-1 mediates TNF-induced osteoclastogenesisQ40909592
The HIV protease inhibitor ritonavir blocks osteoclastogenesis and function by impairing RANKL-induced signalingQ41062466
RANK-mediated amplification of TRAF6 signaling leads to NFATc1 induction during osteoclastogenesis.Q41107411
The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts.Q41649459
A RANK/TRAF6-dependent signal transduction pathway is essential for osteoclast cytoskeletal organization and resorptive functionQ42811314
AML1(-/-) embryos do not express certain hematopoiesis-related gene transcripts including those of the PU.1 gene.Q52182382
Interleukin-17F signaling requires ubiquitination of interleukin-17 receptor via TRAF6.Q55043532
The HIV protease inhibitor ritonavir blocks osteoclastogenesis and function by impairing RANKL-induced signalingQ56101150
P433issue45
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
P304page(s)30861-7
P577publication date2008-11-07
P1433published inJournal of Biological ChemistryQ867727
P1476titleTumor necrosis factor receptor-associated factor 6 is an intranuclear transcriptional coactivator in osteoclasts
P478volume283