scholarly article | Q13442814 |
P2093 | author name string | Ulrich Bierbach | |
Jayati Roy Choudhury | |||
P2860 | cites work | Equilibrium constants for the binding of an homologous series of monofunctional and bifunctional intercalating diacridines to calf thymus DNA | Q44534851 |
Unprecedented monofunctional metalation of adenine nucleobase in guanine- and thymine-containing dinucleotide sequences by a cytotoxic platinum-acridine hybrid agent | Q44540150 | ||
Design, synthesis, and biological properties of new bis(acridine-4-carboxamides) as anticancer agents | Q44635868 | ||
Metal-intercalator-mediated self-association and one-dimensional aggregation in the structure of the excised major DNA adduct of a platinum-acridine agent | Q44834538 | ||
Novel DNA bis-intercalation by MLN944, a potent clinical bisphenazine anticancer drug | Q45022876 | ||
Duplex-promoted platination of adenine-N3 in the minor groove of DNA: challenging a longstanding bioinorganic paradigm | Q45237706 | ||
Solution structural study of a DNA duplex containing the guanine-N7 adduct formed by a cytotoxic platinum-acridine hybrid agent | Q46441863 | ||
DNA minor groove adducts formed by a platinum-acridine conjugate inhibit association of tata-binding protein with its cognate sequence | Q46651162 | ||
Design of a sequence-specific DNA bisintercalator | Q46802972 | ||
Sequence-selective intercalation of antitumour bis-naphthalimides into DNA. Evidence for an approach via the major groove. | Q50536738 | ||
Potential antitumor agents. 34. Quantitative relationships between DNA binding and molecular structure for 9-anilinoacridines substituted in the anilino ring. | Q52435495 | ||
Theoretical aspects of DNA-protein interactions: co-operative and non-co-operative binding of large ligands to a one-dimensional homogeneous lattice. | Q52904158 | ||
Improved nearest-neighbor parameters for predicting DNA duplex stability | Q71099199 | ||
TATA element recognition by the TATA box-binding protein has been conserved throughout evolution | Q27620828 | ||
Solution structure of a quinomycin bisintercalator-DNA complex | Q27730362 | ||
Solution structure of a complex between [N-MeCys3,N-MeCys7]TANDEM and [d(GATATC)]2 | Q27732103 | ||
How proteins recognize the TATA box | Q27733301 | ||
Unique base-step recognition by a platinum-acridinylthiourea conjugate leads to a DNA damage profile complementary to that of the anticancer drug cisplatin | Q31084224 | ||
Biophysical characterization and molecular modeling of the coordinative-intercalative DNA monoadduct of a platinum-acridinylthiourea agent in a site-specifically modified dodecamer | Q33199658 | ||
Hairpin-duplex equilibrium reflected in the A-->B transition in an undecamer quasi-palindrome present in the locus control region of the human beta-globin gene cluster | Q33987083 | ||
DNA polyintercalating drugs: DNA binding of diacridine derivatives | Q35084755 | ||
Circular dichroism spectroscopy of DNA | Q35402010 | ||
Platinum-intercalator conjugates: from DNA-targeted cisplatin derivatives to adenine binding complexes as potential modulators of gene regulation | Q35972641 | ||
The complexities of eukaryotic transcription initiation: regulation of preinitiation complex assembly | Q36924748 | ||
Site selective bis-intercalation of a homodimeric thiazole orange dye in DNA oligonucleotides | Q38297719 | ||
DNA unwinding produced by site-specific intrastrand cross-links of the antitumor drug cis-diamminedichloroplatinum(II). | Q38333904 | ||
Drug--DNA interactions. | Q38335482 | ||
Unusual intercalation of acridin-9-ylthiourea into the 5'-GA/TC DNA base step from the minor groove: implications for the covalent DNA adduct profile of a novel platinum-intercalator conjugate | Q38352682 | ||
DNA bifunctional intercalators. 1. Synthesis and conformational properties of an ethidium homodimer and of an acridine ethidium heterodimer | Q39225649 | ||
Echinomycin: the first bifunctional intercalating agent in clinical trials | Q39839425 | ||
Platinum-acridinylthiourea conjugates show cell line-specific cytotoxic enhancement in H460 lung carcinoma cells compared to cisplatin | Q40422200 | ||
A non-crosslinking platinum-acridine hybrid agent shows enhanced cytotoxicity compared to clinical BCNU and cisplatin in glioblastoma cells. | Q40480043 | ||
Structure-activity relationships in platinum-acridinylthiourea conjugates: effect of the thiourea nonleaving group on drug stability, nucleobase affinity, and in vitro cytotoxicity. | Q40569554 | ||
Bisintercalating threading diacridines: relationships between DNA binding, cytotoxicity, and cell cycle arrest | Q40608732 | ||
Optical absorbance and fluorescence techniques for measuring DNA-drug interactions | Q41667622 | ||
Stacking interactions and intercalative DNA binding | Q41756791 | ||
Proton exchange in DNA-luzopeptin and DNA-echinomycin bisintercalation complexes: rates and processes of base-pair opening. | Q42598667 | ||
DNA Bifunctional intercalators. 2. Fluorescence properties and DNA binding interaction of an ethidium homodimer and an acridine ethidium heterodimer | Q43649070 | ||
Design, synthesis, and biological activity of a novel non-cisplatin-type platinum-acridine pharmacophore | Q43812059 | ||
Mechanism of action of non-cisplatin type DNA-targeted platinum anticancer agents: DNA interactions of novel acridinylthioureas and their platinum conjugates | Q44068264 | ||
Bis(acridinylthiourea)platinum(II) complexes: synthesis, DNA affinity, and biological activity in glioblastoma cells | Q44345465 | ||
P433 | issue | 17 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | platinum | Q880 |
P304 | page(s) | 5622-5632 | |
P577 | publication date | 2005-09-28 | |
P1433 | published in | Nucleic Acids Research | Q135122 |
P1476 | title | Characterization of the bisintercalative DNA binding mode of a bifunctional platinum-acridine agent | |
P478 | volume | 33 |
Q38736001 | A review on acridinylthioureas and its derivatives: biological and cytotoxic activity |
Q42271885 | Complexes of Pd(II) and Pt(II) with 9-aminoacridine: reactions with DNA and study of their antiproliferative activity. |
Q33300909 | Direct observation of the reversible unwinding of a single DNA molecule caused by the intercalation of ethidium bromide |
Q34148697 | Influence of temperature and interactions with ligands on dissociation of dsDNA and ligand-dsDNA complexes of various types of binding. An electrochemical study. |
Q38271731 | Metal complex interactions with DNA. |
Q38573079 | NALDB: nucleic acid ligand database for small molecules targeting nucleic acid. |
Q37219550 | Replacement of a thiourea-S with an amidine-NH donor group in a platinum-acridine antitumor compound reduces the metal's reactivity with cysteine sulfur |
Q36710624 | Structural basis for DNA cleavage by the potent antiproliferative agent (-)-lomaiviticin A |
Q36340171 | Synthesis, aqueous reactivity, and biological evaluation of carboxylic acid ester-functionalized platinum-acridine hybrid anticancer agents |
Q52372388 | The effect of geometric isomerism on the anticancer activity of the monofunctional platinum complex trans-[Pt(NH3)2(phenanthridine)Cl]NO3. |
Q37230414 | Tuning the DNA conformational perturbations induced by cytotoxic platinum-acridine bisintercalators: effect of metal cis/trans isomerism and DNA threading groups |
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