Abstract is: Darwin Prockop (born August 31, 1929) is an American biochemist and progenitor cell researcher. He has held academic posts at several universities, and has been a faculty member at the Texas A&M Health Science Center since 2008. Prockop has been elected to several academic societies, including the National Academy of Sciences and the Institute of Medicine.
| human | Q5 |
| P2671 | Google Knowledge Graph ID | /g/11b_2lyzsb |
| P269 | IdRef ID | 123469627 |
| P5380 | National Academy of Sciences member ID | 59504 |
| P8189 | National Library of Israel J9U ID | 987007373982905171 |
| P214 | VIAF ID | 91966625 |
| P27 | country of citizenship | United States of America | Q30 |
| P69 | educated at | George Washington University | Q432637 |
| Haverford College | Q579611 | ||
| Brasenose College | Q899030 | ||
| Perelman School of Medicine at the University of Pennsylvania | Q4120165 | ||
| P108 | employer | Tulane University | Q1193547 |
| Perelman School of Medicine at the University of Pennsylvania | Q4120165 | ||
| P101 | field of work | biochemistry | Q7094 |
| P463 | member of | National Academy of Sciences | Q270794 |
| National Academy of Medicine | Q4352382 | ||
| P106 | occupation | scientist | Q901 |
| P21 | sex or gender | male | Q6581097 |
| Q40350326 | A crosstalk between myeloma cells and marrow stromal cells stimulates production of DKK1 and interleukin-6: a potential role in the development of lytic bone disease and tumor progression in multiple myeloma. |
| Q45888478 | A subset of human rapidly self-renewing marrow stromal cells preferentially engraft in mice |
| Q92759285 | Absence of Therapeutic Benefit of the Anti-Inflammatory Protein TSG-6 for Corneal Alkali Injury in a Rat Model |
| Q84753164 | Action at a distance: systemically administered adult stem/progenitor cells (MSCs) reduce inflammatory damage to the cornea without engraftment and primarily by secretion of TNF-α stimulated gene/protein 6 |
| Q38344683 | Adipogenic differentiation of human adult stem cells from bone marrow stroma (MSCs). |
| Q36208443 | Adult bone marrow stem/progenitor cells (MSCs) are preconditioned by microenvironmental "niches" in culture: a two-stage hypothesis for regulation of MSC fate. |
| Q45869862 | Adult stem cells from bone marrow (MSCs) isolated from different strains of inbred mice vary in surface epitopes, rates of proliferation, and differentiation potential |
| Q33715133 | Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: potential therapy for cystic fibrosis |
| Q34068369 | Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammatory properties |
| Q40557435 | An Alizarin red-based assay of mineralization by adherent cells in culture: comparison with cetylpyridinium chloride extraction |
| Q42513510 | Angiogenic effects of human multipotent stromal cell conditioned medium activate the PI3K-Akt pathway in hypoxic endothelial cells to inhibit apoptosis, increase survival, and stimulate angiogenesis |
| Q34165745 | Anti-inflammatory protein TSG-6 reduces inflammatory damage to the cornea following chemical and mechanical injury. |
| Q35112231 | Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF-κB signaling in resident macrophages. |
| Q45876285 | Assays of MSCs with microarrays |
| Q45873052 | Bone marrow progenitor cells contribute to repair and remodeling of the lung and heart in a rat model of progressive pulmonary hypertension. |
| Q37369478 | Cancer cells enter dormancy after cannibalizing mesenchymal stem/stromal cells (MSCs). |
| Q35751008 | Clinical trials with adult stem/progenitor cells for tissue repair: let's not overlook some essential precautions |
| Q40436729 | Comparison of effect of BMP-2, -4, and -6 on in vitro cartilage formation of human adult stem cells from bone marrow stroma |
| Q39191209 | Comparison of the anti-inflammatory effects of induced pluripotent stem cell-derived and bone marrow-derived mesenchymal stromal cells in a murine model of corneal injury. |
| Q48874383 | Cross-talk between human mesenchymal stem/progenitor cells (MSCs) and rat hippocampal slices in LPS-stimulated cocultures: the MSCs are activated to secrete prostaglandin E2. |
| Q38710511 | Data against a Common Assumption: Xenogeneic Mouse Models Can Be Used to Assay Suppression of Immunity by Human MSCs |
| Q47584701 | Defining the risks of mesenchymal stromal cell therapy |
| Q34805642 | Differentiation, cell fusion, and nuclear fusion during ex vivo repair of epithelium by human adult stem cells from bone marrow stroma |
| Q45879029 | Dkk-1-derived synthetic peptides and lithium chloride for the control and recovery of adult stem cells from bone marrow. |
| Q36333354 | Drosha regulates hMSCs cell cycle progression through a miRNA independent mechanism. |
| Q30557479 | Dynamic compaction of human mesenchymal stem/precursor cells into spheres self-activates caspase-dependent IL1 signaling to enhance secretion of modulators of inflammation and immunity (PGE2, TSG6, and STC1). |
| Q36013643 | Engraftment of bone marrow progenitor cells in a rat model of asbestos-induced pulmonary fibrosis |
| Q36372136 | Evolving paradigms for repair of tissues by adult stem/progenitor cells (MSCs). |
| Q45856815 | Expansion of human adult stem cells from bone marrow stroma: conditions that maximize the yields of early progenitors and evaluate their quality |
| Q34634142 | Histamine receptor H1 and dermatopontin: new downstream targets of the vitamin D receptor. |
| Q36167459 | How Wnt signaling affects bone repair by mesenchymal stem cells from the bone marrow |
| Q60952476 | Human induced pluripotent stem cell-derived MGE cell grafting after status epilepticus attenuates chronic epilepsy and comorbidities via synaptic integration |
| Q41810028 | Human mesenchymal stem/stromal cells cultured as spheroids are self-activated to produce prostaglandin E2 that directs stimulated macrophages into an anti-inflammatory phenotype. |
| Q45867011 | Human mesenchymal stromal cells (MSCs) reduce neointimal hyperplasia in a mouse model of flow-restriction by transient suppression of anti-inflammatory cytokines |
| Q24302245 | Human multipotent stromal cells attenuate lipopolysaccharide-induced acute lung injury in mice via secretion of tumor necrosis factor-α-induced protein 6 |
| Q36985192 | Human multipotent stromal cells from bone marrow and microRNA: regulation of differentiation and leukemia inhibitory factor expression. |
| Q45871767 | Human multipotent stromal cells undergo sharp transition from division to development in culture |
| Q42031458 | Human stem/progenitor cells from bone marrow enhance glial differentiation of rat neural stem cells: a role for transforming growth factor β and Notch signaling |
| Q24534272 | Human stem/progenitor cells from bone marrow promote neurogenesis of endogenous neural stem cells in the hippocampus of mice |
| Q36111353 | Identification of the HSPB4/TLR2/NF-κB axis in macrophage as a therapeutic target for sterile inflammation of the cornea. |
| Q34048231 | In vitro cartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis |
| Q24324389 | Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels |
| Q44878272 | Internalized antigens must be removed to prepare hypoimmunogenic mesenchymal stem cells for cell and gene therapy |
| Q33620044 | Intranasal MSC-derived A1-exosomes ease inflammation, and prevent abnormal neurogenesis and memory dysfunction after status epilepticus. |
| Q92326472 | Intranasally Administered Human MSC-Derived Extracellular Vesicles Pervasively Incorporate into Neurons and Microglia in both Intact and Status Epilepticus Injured Forebrain |
| Q27322349 | Intraperitoneally infused human mesenchymal stem cells form aggregates with mouse immune cells and attach to peritoneal organs. |
| Q36401080 | Intravenous mesenchymal stem cells prevented rejection of allogeneic corneal transplants by aborting the early inflammatory response |
| Q91343562 | In Vitro Macrophage Assay Predicts the In Vivo Anti-inflammatory Potential of Exosomes from Human Mesenchymal Stromal Cells |
| Q45877586 | Isolation of a highly clonogenic and multipotential subfraction of adult stem cells from bone marrow stroma |
| Q33659353 | MSC-derived Extracellular Vesicles Attenuate Immune Responses in Two Autoimmune Murine Models: Type 1 Diabetes and Uveoretinitis |
| Q47209508 | Mesenchymal Stromal Cells Inhibit Inflammatory Lymphangiogenesis in the Cornea by Suppressing Macrophage in a TSG-6-Dependent Manner |
| Q35665181 | Mesenchymal stem/stromal cells (MSCs): role as guardians of inflammation |
| Q39048543 | Mesenchymal stem/stromal cells inhibit the NLRP3 inflammasome by decreasing mitochondrial reactive oxygen species |
| Q36459369 | Mesenchymal stem/stromal cells precondition lung monocytes/macrophages to produce tolerance against allo- and autoimmunity in the eye. |
| Q41020605 | Mesenchymal stromal cells protect cancer cells from ROS-induced apoptosis and enhance the Warburg effect by secreting STC1 |
| Q45877224 | Methods and protocols. Preface |
| Q30476644 | Mitochondrial transfer between cells can rescue aerobic respiration |
| Q42853310 | Multipotent human stromal cells improve cardiac function after myocardial infarction in mice without long-term engraftment |
| Q36547021 | Multipotent stromal cells are activated to reduce apoptosis in part by upregulation and secretion of stanniocalcin-1. |
| Q30478228 | Multipotent stromal cells from human marrow home to and promote repair of pancreatic islets and renal glomeruli in diabetic NOD/scid mice. |
| Q36144893 | Non-hematopoietic bone marrow stem cells: molecular control of expansion and differentiation |
| Q45859372 | Novel object recognition in Apoe(-/-) mice improved by neonatal implantation of wild-type multipotential stromal cells |
| Q34582606 | One strategy for cell and gene therapy: harnessing the power of adult stem cells to repair tissues. |
| Q33372606 | Pharmaceutical induction of ApoE secretion by multipotent mesenchymal stromal cells (MSCs). |
| Q37576082 | Phase-directed therapy: TSG-6 targeted to early inflammation improves bleomycin-injured lungs |
| Q39246780 | Preactivation of human MSCs with TNF-α enhances tumor-suppressive activity |
| Q27314509 | Rapidly self-renewing human multipotent marrow stromal cells (hMSC) express sialyl Lewis X and actively adhere to arterial endothelium in a chick embryo model system |
| Q35317290 | Rat adult stem cells (marrow stromal cells) engraft and differentiate in chick embryos without evidence of cell fusion |
| Q37067312 | Reversible commitment to differentiation by human multipotent stromal cells in single-cell-derived colonies |
| Q40220522 | Sarcoma derived from cultured mesenchymal stem cells |
| Q35899925 | Scalable Production of a Multifunctional Protein (TSG-6) That Aggregates with Itself and the CHO Cells That Synthesize It. |
| Q38347790 | Serum deprivation of human marrow stromal cells (hMSCs) selects for a subpopulation of early progenitor cells with enhanced expression of OCT-4 and other embryonic genes. |
| Q33283525 | Short-term exposure of multipotent stromal cells to low oxygen increases their expression of CX3CR1 and CXCR4 and their engraftment in vivo |
| Q46100686 | Small-molecule antagonist of macrophage migration inhibitory factor enhances migratory response of mesenchymal stem cells to bronchial epithelial cells |
| Q24338730 | Sox11 is expressed in early progenitor human multipotent stromal cells and decreases with extensive expansion of the cells |
| Q39549057 | Stanniocalcin-1 attenuates ischemic cardiac injury and response of differentiating monocytes/macrophages to inflammatory stimuli |
| Q27331304 | Stanniocalcin-1 regulates extracellular ATP-induced calcium waves in human epithelial cancer cells by stimulating ATP release from bystander cells |
| Q41974923 | Stanniocalcin-1 rescued photoreceptor degeneration in two rat models of inherited retinal degeneration |
| Q36936307 | Stem/progenitor cells from bone marrow decrease neuronal death in global ischemia by modulation of inflammatory/immune responses |
| Q34601443 | TSG-6 as a biomarker to predict efficacy of human mesenchymal stem/progenitor cells (hMSCs) in modulating sterile inflammation in vivo. |
| Q37071096 | The CD34-like protein PODXL and alpha6-integrin (CD49f) identify early progenitor MSCs with increased clonogenicity and migration to infarcted heart in mice |
| Q28203591 | The Wnt signaling inhibitor dickkopf-1 is required for reentry into the cell cycle of human adult stem cells from bone marrow |
| Q34307885 | Unique characteristics of human mesenchymal stromal/progenitor cells pre-activated in 3-dimensional cultures under different conditions. |
| Q38316400 | Use of differentiating adult stem cells (marrow stromal cells) to identify new downstream target genes for transcription factors |
| Darwin Prockop | wikipedia |
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