Cancer Evolution and the Limits of Predictability in Precision Cancer Medicine

scientific article

Cancer Evolution and the Limits of Predictability in Precision Cancer Medicine is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.TRECAN.2015.11.003
P3181OpenCitations bibliographic resource ID2575881
P932PMC publication ID4756277
P698PubMed publication ID26949746
P5875ResearchGate publication ID292346746

P50authorLouise J BarberQ57334442
Marco GerlingerQ30347474
Andrea SottorivaQ39031024
P2093author name stringMatthew Ashenden
Matthew N Davies
Kamil A Lipinski
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ALK inhibitors in non-small cell lung cancer: crizotinib and beyondQ34431889
Spatial and temporal diversity in genomic instability processes defines lung cancer evolutionQ34442770
The architecture and evolution of cancer neochromosomesQ34454339
Timing and heterogeneity of mutations associated with drug resistance in metastatic cancersQ34525966
Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution.Q34946877
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Paradoxical relationship between chromosomal instability and survival outcome in cancerQ34988001
Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemiaQ34997508
A functional landscape of resistance to ALK inhibition in lung cancerQ35438912
Systematic evaluation of the prognostic impact and intratumour heterogeneity of clear cell renal cell carcinoma biomarkersQ35540073
The evolutionary history of lethal metastatic prostate cancerQ35548366
Tumor clone dynamics in lethal prostate cancerQ35575930
Studying clonal dynamics in response to cancer therapy using high-complexity barcoding.Q35596310
Evidence for multiple adaptive peaks from populations of bacteria evolving in a structured habitatQ35760235
APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and HeterogeneityQ35836909
Subclonal diversification of primary breast cancer revealed by multiregion sequencingQ35847434
A Big Bang model of human colorectal tumor growthQ36074227
The Allelic Context of the C797S Mutation Acquired upon Treatment with Third-Generation EGFR Inhibitors Impacts Sensitivity to Subsequent Treatment StrategiesQ36104980
Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencingQ36256943
Effect of mutation order on myeloproliferative neoplasmsQ36320344
Predictability of evolution depends nonmonotonically on population sizeQ36535179
Evolution and impact of subclonal mutations in chronic lymphocytic leukemiaQ36619124
Impact of deleterious passenger mutations on cancer progressionQ36637272
Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics.Q36673354
Molecular and genetic properties of tumors associated with local immune cytolytic activityQ36869059
Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution.Q36892577
Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution.Q36991078
Exploiting ecological principles to better understand cancer progression and treatment.Q37561441
Acquired resistance and clonal evolution in melanoma during BRAF inhibitor therapyQ37606223
Genomic medicine frontier in human solid tumors: prospects and challengesQ38099305
Universality and predictability in molecular quantitative genetics.Q38167547
Empirical fitness landscapes and the predictability of evolutionQ38218962
Molecular mechanisms of resistance in epidermal growth factor receptor-mutant lung adenocarcinomasQ38245208
Cancer: evolution within a lifetimeQ38257835
Resistance to anti-EGFR therapy in colorectal cancer: from heterogeneity to convergent evolutionQ38257912
Dissecting cancer evolution at the macro-heterogeneity and micro-heterogeneity scale.Q38305991
Mapping spatial heterogeneity in the tumor microenvironment: a new era for digital pathology.Q38323254
A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneityQ38843089
Prospective derivation of a living organoid biobank of colorectal cancer patients.Q38877277
Heterogeneity Underlies the Emergence of EGFRT790 Wild-Type Clones Following Treatment of T790M-Positive Cancers with a Third-Generation EGFR InhibitorQ38880070
Clinical relevance of KRAS-mutated subclones detected with picodroplet digital PCR in advanced colorectal cancer treated with anti-EGFR therapyQ40224084
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Tracking the clonal origin of lethal prostate cancerQ41762568
The effect of one additional driver mutation on tumor progression.Q41846748
Deterministic and stochastic regimes of asexual evolution on rugged fitness landscapesQ42041571
Human mutation rate associated with DNA replication timingQ42085559
Cancer stem cells as 'units of selection'.Q42108136
Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.Q42183079
APOBEC-mediated cytosine deamination links PIK3CA helical domain mutations to human papillomavirus-driven tumor developmentQ42213577
Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencingQ43118556
Tumor burden is predictive of survival in patients with non-small-cell lung cancer and with activating epidermal growth factor receptor mutations who receive gefitinibQ43795365
Genetic variegation of clonal architecture and propagating cells in leukaemiaQ44426152
The molecular diversity of adaptive convergence.Q46185374
Finding of kinase domain mutations in patients with chronic phase chronic myeloid leukemia responding to imatinib may identify those at high risk of disease progressionQ46470629
Acquired resistance to crizotinib from a mutation in CD74-ROS1.Q46932181
Whole-genome characterization of chemoresistant ovarian cancerQ50272478
P433issue1
P304page(s)49-63
P577publication date2016-01-01
P1433published inTrends in cancerQ27726777
P1476titleCancer Evolution and the Limits of Predictability in Precision Cancer Medicine
P478volume2

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