| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1045627677 |
| P356 | DOI | 10.1038/NRC3816 |
| P3181 | OpenCitations bibliographic resource ID | 872195 |
| P932 | PMC publication ID | 4280484 |
| P698 | PubMed publication ID | 25568919 |
| P50 | author | Dmitry A. Gordenin | Q55130852 |
| P2093 | author name string | Steven A Roberts | |
| P2860 | cites work | Population stratification of a common APOBEC gene deletion polymorphism | Q21563457 |
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| Mutational heterogeneity in cancer and the search for new cancer-associated genes | Q24606956 | ||
| Melanoma genome sequencing reveals frequent PREX2 mutations | Q24610463 | ||
| Aristolochic acid-associated urothelial cancer in Taiwan | Q24616582 | ||
| Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas | Q24617520 | ||
| Mutational processes molding the genomes of 21 breast cancers | Q24620915 | ||
| A comprehensive catalogue of somatic mutations from a human cancer genome | Q24628532 | ||
| Comprehensive molecular characterization of human colon and rectal cancer | Q24630415 | ||
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| Comprehensive genomic characterization defines human glioblastoma genes and core pathways | Q24656128 | ||
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| Comprehensive molecular characterization of urothelial bladder carcinoma | Q28306864 | ||
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| Switching from high-fidelity replicases to low-fidelity lesion-bypass polymerases | Q35804585 | ||
| Mismatch repair and DNA damage signalling | Q35848516 | ||
| Evidence for mutation showers | Q35850189 | ||
| Lack of recognition by global-genome nucleotide excision repair accounts for the high mutagenicity and persistence of aristolactam-DNA adducts | Q35860570 | ||
| Oxidative DNA damage and disease: induction, repair and significance | Q35876708 | ||
| Genotoxicity of tobacco smoke and tobacco smoke condensate: a review | Q35968076 | ||
| Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions. | Q35992079 | ||
| A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers | Q36129157 | ||
| A role for AID in chromosome translocations between c-myc and the IgH variable region. | Q36229681 | ||
| Mutagenesis at methylated CpG sequences. | Q36434842 | ||
| Translesion synthesis DNA polymerases and control of genome stability | Q36486621 | ||
| Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability | Q36580560 | ||
| CRAVAT: cancer-related analysis of variants toolkit | Q36638544 | ||
| Somatic hypermutation: activation-induced deaminase for C/G followed by polymerase eta for A/T. | Q36693193 | ||
| Two Mechanisms Produce Mutation Hotspots at DNA Breaks in Escherichia coli | Q36713351 | ||
| A common deletion in the APOBEC3 genes and breast cancer risk | Q36769624 | ||
| Genomic landscape of non-small cell lung cancer in smokers and never-smokers | Q36851245 | ||
| A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy | Q48582050 | ||
| Low fidelity DNA synthesis by human DNA polymerase-eta | Q50335566 | ||
| Chromatin organization is a major influence on regional mutation rates in human cancer cells | Q52837652 | ||
| Frequent POLE1 p.S297F mutation in Chinese patients with ovarian endometrioid carcinoma | Q54381457 | ||
| Novel Mutagenic Properties of Abasic Sites inSaccharomyces cerevisiae | Q54606410 | ||
| Aristolochic acids | Q54726929 | ||
| Somatic mutation hotspots correlate with DNA polymerase eta error spectrum. | Q55034838 | ||
| Multiple Mechanisms Control Chromosome Integrity after Replication Fork Uncoupling and Restart at Irreparable UV Lesions | Q58883733 | ||
| Abstract 5461: The role of gene body cytosine modifications in MGMT expression and sensitivity to temozolomide | Q60136814 | ||
| DNA deaminases AID and APOBEC3G act processively on single-stranded DNA | Q61762218 | ||
| Radiation | Q85558912 | ||
| Evidence of associations of APOBEC3B gene deletion with susceptibility to persistent HBV infection and hepatocellular carcinoma | Q85615153 | ||
| DNA damage response as an anti-cancer barrier: damage threshold and the concept of 'conditional haploinsufficiency'. | Q36910861 | ||
| Progress and challenges in selected areas of tobacco carcinogenesis | Q36916827 | ||
| Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity | Q36918993 | ||
| Punctuated evolution of prostate cancer genomes | Q36950514 | ||
| The biochemistry of somatic hypermutation | Q37096080 | ||
| APOBEC3 deletion polymorphism is associated with breast cancer risk among women of European ancestry | Q37205864 | ||
| An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers | Q37211712 | ||
| Oxidative stress-induced mutagenesis in single-strand DNA occurs primarily at cytosines and is DNA polymerase zeta-dependent only for adenines and guanines | Q37236755 | ||
| AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations | Q37269390 | ||
| The choice of nucleotide inserted opposite abasic sites formed within chromosomal DNA reveals the polymerase activities participating in translesion DNA synthesis | Q37302944 | ||
| Hepatitis C virus induces a mutator phenotype: enhanced mutations of immunoglobulin and protooncogenes | Q37356991 | ||
| The landscape of microsatellite instability in colorectal and endometrial cancer genomes | Q37412188 | ||
| Hypermutation of the inactive X chromosome is a frequent event in cancer | Q37503144 | ||
| Heterogeneity of genomic evolution and mutational profiles in multiple myeloma | Q37528285 | ||
| APOBEC3B is an enzymatic source of mutation in breast cancer. | Q37533713 | ||
| MLH1-silenced and non-silenced subgroups of hypermutated colorectal carcinomas have distinct mutational landscapes | Q37588178 | ||
| Mechanisms of base substitution mutagenesis in cancer genomes | Q37689834 | ||
| Exploring the Genomes of Cancer Cells: Progress and Promise | Q37857590 | ||
| Similarities and differences between "uncapped" telomeres and DNA double-strand breaks. | Q37971853 | ||
| Mutations arising during repair of chromosome breaks | Q38059260 | ||
| DNA base damage by reactive oxygen species, oxidizing agents, and UV radiation. | Q38078916 | ||
| Translesion DNA synthesis and mutagenesis in eukaryotes | Q38086224 | ||
| The evolution of the unstable cancer genome | Q38198432 | ||
| Mismatch repair deficient human cells: spontaneous and MNNG-induced mutational spectra in the HPRT gene | Q38311693 | ||
| RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia | Q38367298 | ||
| Certain imidazotetrazines escape O6-methylguanine-DNA methyltransferase and mismatch repair. | Q39514906 | ||
| Is there any genetic instability in human cancer? | Q39683908 | ||
| DNA replication timing and higher-order nuclear organization determine single-nucleotide substitution patterns in cancer genomes | Q40015551 | ||
| APOBEC3G DNA deaminase acts processively 3' --> 5' on single-stranded DNA. | Q40290523 | ||
| Reactions of oxyl radicals with DNA. | Q40456587 | ||
| Distribution and repair of photolesions in DNA: genetic consequences and the role of sequence context | Q40854412 | ||
| Hypermutability and mismatch repair deficiency in RER+ tumor cells | Q41508298 | ||
| Mutagenesis by hydrogen peroxide treatment of mammalian cells: a molecular analysis | Q41745214 | ||
| Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome | Q41870312 | ||
| Identification of higher-order functional domains in the human ENCODE regions | Q41981321 | ||
| Human mutation rate associated with DNA replication timing | Q42085559 | ||
| APOBEC-mediated cytosine deamination links PIK3CA helical domain mutations to human papillomavirus-driven tumor development | Q42213577 | ||
| Reply: Is There Any Genetic Instability in Human Cancer? | Q42595433 | ||
| Clues to the pathogenesis of familial colorectal cancer | Q42622043 | ||
| In situ analyses of genome instability in breast cancer | Q46051522 | ||
| Mutation spectrum of copper-induced DNA damage | Q46488384 | ||
| Functional uncoupling of twin polymerases: mechanism of polymerase dissociation from a lagging-strand block. | Q47968713 | ||
| The Origin and Evolution of Mutations in Acute Myeloid Leukemia | Q29614630 | ||
| The life history of 21 breast cancers | Q29614642 | ||
| Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia | Q29614659 | ||
| DNA replication fidelity | Q29616841 | ||
| Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations | Q30040534 | ||
| High-resolution characterization of a hepatocellular carcinoma genome | Q31005512 | ||
| Cutting edge: DGYW/WRCH is a better predictor of mutability at G:C bases in Ig hypermutation than the widely accepted RGYW/WRCY motif and probably reflects a two-step activation-induced cytidine deaminase-triggered process | Q33198930 | ||
| Changes in the expression of telomere maintenance genes suggest global telomere dysfunction in B-chronic lymphocytic leukemia | Q33310158 | ||
| Splenic marginal zone lymphomas are characterized by loss of interstitial regions of chromosome 7q, 7q31.32 and 7q36.2 that include the protection of telomere 1 (POT1) and sonic hedgehog (SHH) genes | Q33336192 | ||
| Nonnegative matrix factorization: an analytical and interpretive tool in computational biology | Q33354938 | ||
| Epidemiology of doublet/multiplet mutations in lung cancers: evidence that a subset arises by chronocoordinate events | Q33384115 | ||
| Hypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae. | Q33385991 | ||
| Hypermutable non-synonymous sites are under stronger negative selection | Q33388221 | ||
| The role of gene body cytosine modifications in MGMT expression and sensitivity to temozolomide | Q33578787 | ||
| Functions and regulation of the APOBEC family of proteins | Q33595661 | ||
| Break-induced replication repair of damaged forks induces genomic duplications in human cells. | Q33719358 | ||
| Whole-genome reconstruction and mutational signatures in gastric cancer. | Q33751188 | ||
| Mutation signatures of carcinogen exposure: genome-wide detection and new opportunities for cancer prevention | Q33772624 | ||
| Break-induced replication is highly inaccurate | Q33828325 | ||
| Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment | Q33865925 | ||
| Ultraviolet radiation accelerates BRAF-driven melanomagenesis by targeting TP53 | Q33955442 | ||
| Reduced local mutation density in regulatory DNA of cancer genomes is linked to DNA repair | Q33976821 | ||
| INDUCTION OF SPECIFIC MUTATIONS WITH 5-BROMOURACIL. | Q33994694 | ||
| A time-invariant principle of genome evolution | Q34059478 | ||
| Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer | Q34062924 | ||
| Clustered and genome-wide transient mutagenesis in human cancers: Hypermutation without permanent mutators or loss of fitness | Q34090613 | ||
| The mutation spectrum revealed by paired genome sequences from a lung cancer patient | Q34117627 | ||
| AID and somatic hypermutation. | Q34118000 | ||
| A single-strand specific lesion drives MMS-induced hyper-mutability at a double-strand break in yeast | Q34153868 | ||
| Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers | Q34154480 | ||
| Chromosome catastrophes involve replication mechanisms generating complex genomic rearrangements | Q34217081 | ||
| Theoretical analysis of mutation hotspots and their DNA sequence context specificity | Q34218124 | ||
| R Loops: From Transcription Byproducts to Threats to Genome Stability | Q34271508 | ||
| Absolute quantification of somatic DNA alterations in human cancer | Q34271693 | ||
| Differential relationship of DNA replication timing to different forms of human mutation and variation | Q34313413 | ||
| DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis | Q34340260 | ||
| Evidence for APOBEC3B mutagenesis in multiple human cancers | Q34357412 | ||
| Genome-wide mutational signatures of aristolochic acid and its application as a screening tool | Q34362611 | ||
| Mutational signature of aristolochic acid exposure as revealed by whole-exome sequencing | Q34362617 | ||
| Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma | Q34391844 | ||
| Mutations induced by ultraviolet light | Q34400112 | ||
| The relative roles in vivo of Saccharomyces cerevisiae Pol eta, Pol zeta, Rev1 protein and Pol32 in the bypass and mutation induction of an abasic site, T-T (6-4) photoadduct and T-T cis-syn cyclobutane dimer | Q34570808 | ||
| Uracil in DNA and its processing by different DNA glycosylases | Q34600267 | ||
| DNA end resection—Unraveling the tail | Q34612802 | ||
| Microsatellite instability in colorectal cancer-the stable evidence | Q34616565 | ||
| DNA replication timing | Q34654036 | ||
| Aristolochic acid as a probable human cancer hazard in herbal remedies: a review. | Q34731630 | ||
| Break-induced replication is a source of mutation clusters underlying kataegis | Q34757099 | ||
| Balancing AID and DNA repair during somatic hypermutation | Q34966633 | ||
| Damage-induced localized hypermutability. | Q35002361 | ||
| Evidence that pyrimidine dimers in DNA can give rise to tumors | Q35052642 | ||
| Emerging landscape of oncogenic signatures across human cancers | Q35058708 | ||
| Patterns and processes of somatic mutations in nine major cancers | Q35097963 | ||
| Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers | Q35345680 | ||
| Structure, function and evolution of CpG island promoters | Q35541032 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 786-800 | |
| P577 | publication date | 2014-12-01 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Nature Reviews Cancer | Q641657 |
| P1476 | title | Hypermutation in human cancer genomes: footprints and mechanisms | |
| P478 | volume | 14 |
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| Q42265689 | *K-means and cluster models for cancer signatures |
| Q27704805 | 1.92 Angstrom Zinc-Free APOBEC3F Catalytic Domain Crystal Structure |
| Q37739072 | A Novel Regulator of Activation-Induced Cytidine Deaminase/APOBECs in Immunity and Cancer: Schrödinger's CATalytic Pocket |
| Q90212126 | A Rabbit Monoclonal Antibody against the Antiviral and Cancer Genomic DNA Mutating Enzyme APOBEC3B |
| Q42363667 | A network of epigenetic modifiers and DNA repair genes controls tissue-specific copy number alteration preference. |
| Q91666298 | A practical guide for mutational signature analysis in hematological malignancies |
| Q39429299 | A weighted exact test for mutually exclusive mutations in cancer |
| Q35836909 | APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity |
| Q47555165 | APOBEC mutagenesis in drug resistance and immune escape in HIV and cancer evolution |
| Q36278984 | APOBEC-Induced Cancer Mutations Are Uniquely Enriched in Early-Replicating, Gene-Dense, and Active Chromatin Regions |
| Q36506737 | APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication |
| Q38742812 | APOBEC3A associates with human papillomavirus genome integration in oropharyngeal cancers. |
| Q40063761 | APOBEC3A is an oral cancer prognostic biomarker in Taiwanese carriers of an APOBEC deletion polymorphism |
| Q50000508 | APOBEC3A/B deletion polymorphism and cancer risk |
| Q54202903 | APOBEC3B Nuclear Localization Requires two Distinct N-Terminal Domain Surfaces |
| Q52562762 | APOBEC3B and APOBEC mutational signature as potential predictive markers for immunotherapy response in non-small cell lung cancer. |
| Q38870507 | APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast. |
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| Q46844461 | Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B. |
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| Q42575965 | Correlation of Apobec Mrna Expression with overall Survival and pd-l1 Expression in Urothelial Carcinoma |
| Q52719995 | Correlation of gene expression and associated mutation profiles of APOBEC3A, APOBEC3B, REV1, UNG, and FHIT with chemosensitivity of cancer cell lines to drug treatment |
| Q57183364 | CpG binding protein (CFP1) occupies open chromatin regions of active genes, including enhancers and non-CpG islands |
| Q58602209 | Criticality in tumor evolution and clinical outcome |
| Q36301232 | Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain |
| Q90419584 | Current Perspectives in Cancer Immunotherapy |
| Q46665792 | DNA polymerase η mutational signatures are found in a variety of different types of cancer |
| Q38261732 | Degradation of the cancer genomic DNA deaminase APOBEC3B by SIV Vif |
| Q41006849 | Detection of hypermutated human papillomavirus type 16 genome by Next-Generation Sequencing |
| Q49347721 | Determinants and clinical implications of chromosomal instability in cancer |
| Q28547015 | Disruption of Transcriptional Coactivator Sub1 Leads to Genome-Wide Re-distribution of Clustered Mutations Induced by APOBEC in Active Yeast Genes |
| Q53820712 | Distinctive types of postzygotic single-nucleotide mosaicisms in healthy individuals revealed by genome-wide profiling of multiple organs. |
| Q36319724 | Epigenomic annotation of noncoding mutations identifies mutated pathways in primary liver cancer |
| Q41233203 | Error-prone DNA polymerase and oxidative stress increase the incidences of A to G mutations in tumors |
| Q90228034 | Error-prone bypass of DNA lesions during lagging-strand replication is a common source of germline and cancer mutations |
| Q64108588 | Errors in translational decoding: tRNA wobbling or misincorporation? |
| Q39022234 | Eukaryotic DNA Polymerases in Homologous Recombination |
| Q90362956 | Fighting Against Promoter DNA Hyper-Methylation: Protective Histone Modification Profiles of Stress-Resistant Intestinal Stem Cells |
| Q98289858 | Finding new cancer epigenetic and genetic biomarkers from cell-free DNA by combining SALP-seq and machine learning |
| Q39336400 | From Telomere Crisis via Dicentric Chromosomes to Kataegis and Chromothripsis |
| Q38943944 | Functions and Malfunctions of Mammalian DNA-Cytosine Deaminases |
| Q89480630 | GC content elevates mutation and recombination rates in the yeast Saccharomyces cerevisiae |
| Q26801374 | Genetic instability in the tumor microenvironment: a new look at an old neighbor |
| Q47982607 | Genome-wide maps of alkylation damage, repair, and mutagenesis in yeast reveal mechanisms of mutational heterogeneity. |
| Q38779428 | Genomic pathobiology of gastric carcinoma |
| Q40150522 | Heat shock proteins stimulate APOBEC-3-mediated cytidine deamination in the hepatitis B virus |
| Q36948373 | High-Grade Neuroendocrine Colorectal Carcinomas: A Retrospective Study of 100 Patients |
| Q48271035 | Human DNA Repair Genes Possess Potential G-Quadruplex Sequences in Their Promoters and 5'-Untranslated Regions. |
| Q38721814 | Human Papillomavirus 16 E6 Upregulates APOBEC3B via the TEAD Transcription Factor |
| Q47655313 | Hypermutation and microsatellite instability in gastrointestinal cancers |
| Q42319791 | Identification of outcome-related driver mutations in cancer using conditional co-occurrence distributions. |
| Q38907925 | Immune checkpoint inhibition and its relationship with hypermutation phenoytype as a potential treatment for Glioblastoma |
| Q64114653 | Integrated structural variation and point mutation signatures in cancer genomes using correlated topic models |
| Q28088334 | Invasive Bladder Cancer: Genomic Insights and Therapeutic Promise |
| Q90631641 | Landscape of Mitochondria Genome and Clinical Outcomes in Stage 1 Lung Adenocarcinoma |
| Q88013125 | Landscape of Tumor Mutation Load, Mismatch Repair Deficiency, and PD-L1 Expression in a Large Patient Cohort of Gastrointestinal Cancers |
| Q35656749 | Local DNA dynamics shape mutational patterns of mononucleotide repeats in human genomes |
| Q64106752 | Location analysis of 8-oxo-7,8-dihydroguanine in DNA by polymerase-mediated differential coding |
| Q47135439 | MEN1 gene mutation with parathyroid carcinoma: first report of a familial case. |
| Q55147779 | Modeling cancer rearrangement landscapes. |
| Q57173759 | Modeling the Embrace of a Mutator: APOBEC Selection of Nucleic Acid Ligands |
| Q28070038 | Molecular Diagnostics for Precision Medicine in Colorectal Cancer: Current Status and Future Perspective |
| Q64119975 | Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories |
| Q91895408 | Molecular model linking Th2 polarized M2 tumour-associated macrophages with deaminase-mediated cancer progression mutation signatures |
| Q33740850 | MosaicHunter: accurate detection of postzygotic single-nucleotide mosaicism through next-generation sequencing of unpaired, trio, and paired samples |
| Q36013147 | Mutation Processes in 293-Based Clones Overexpressing the DNA Cytosine Deaminase APOBEC3B. |
| Q89059642 | Mutation Signatures Including APOBEC in Cancer Cell Lines |
| Q36565742 | Mutation pattern is an influential factor on functional mutation rates in cancer |
| Q90058009 | Mutation signatures specific to DNA alkylating agents in yeast and cancers |
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| Q55060101 | Mutational signatures and mutable motifs in cancer genomes. |
| Q94483849 | Mutational signatures are jointly shaped by DNA damage and repair |
| Q91853012 | Mutational signatures of redox stress in yeast single-strand DNA and of aging in human mitochondrial DNA share a common feature |
| Q59354957 | Mutations in and nucleotide excision repair genes are correlated with prognosis of hepatitis B virus-associated hepatocellular carcinoma |
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| Q34554690 | Prostate cancer: Clinical hallmarks in whole cancer genomes |
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| Q49388555 | Recombination Is Responsible for the Increased Recovery of Drug-Resistant Mutants with Hypermutated Genomes in Resting Yeast Diploids Expressing APOBEC Deaminases. |
| Q28067125 | Repair of DNA Double-Strand Breaks in Heterochromatin |
| Q92488841 | Repair of base damage within break-induced replication intermediates promotes kataegis associated with chromosome rearrangements |
| Q46424290 | Sequencing the Mouse Genome for the Oxidatively Modified Base 8-Oxo-7,8-dihydroguanine by OG-Seq. |
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