scholarly article | Q13442814 |
P2093 | author name string | Yu-Cheng Su | |
Steve R Roffler | |||
Talal Salem Al-Qaisi | |||
P2860 | cites work | Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation | Q24300395 |
Somatic hypermutation of the AID transgene in B and non-B cells | Q24535846 | ||
Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase | Q24683335 | ||
Expression of activation-induced cytidine deaminase in human B-cell non-Hodgkin lymphomas | Q28201588 | ||
AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification | Q28208979 | ||
Hypermutation in human cancer genomes: footprints and mechanisms | Q28255066 | ||
Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis | Q28506864 | ||
Genome-wide mutation avalanches induced in diploid yeast cells by a base analog or an APOBEC deaminase | Q28536837 | ||
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme | Q29547201 | ||
Integrity of the AID serine-38 phosphorylation site is critical for class switch recombination and somatic hypermutation in mice | Q30857687 | ||
Estimating Hypermutation Rates from Clonal Tree Data | Q30882543 | ||
Why high-error-rate random mutagenesis libraries are enriched in functional and improved proteins | Q33216570 | ||
Isolation of anti-CD22 Fv with high affinity by Fv display on human cells | Q33246226 | ||
Whole IgG surface display on mammalian cells: Application to isolation of neutralizing chicken monoclonal anti-IL-12 antibodies | Q33295087 | ||
Display and selection of scFv antibodies on HEK-293T cells | Q33474388 | ||
Genome-wide somatic hypermutation | Q33905110 | ||
Modeling and optimization of populations subject to time-dependent mutation | Q33958359 | ||
Clustered and genome-wide transient mutagenesis in human cancers: Hypermutation without permanent mutators or loss of fitness | Q34090613 | ||
Coupling mammalian cell surface display with somatic hypermutation for the discovery and maturation of human antibodies | Q34096649 | ||
The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia | Q34099472 | ||
AID and somatic hypermutation. | Q34118000 | ||
A source of the single-stranded DNA substrate for activation-induced deaminase during somatic hypermutation | Q34133261 | ||
Affinity maturation of anti-TNF-alpha scFv with somatic hypermutation in non-B cells | Q34216459 | ||
Mimicking the germinal center reaction in hybridoma cells to isolate temperature-selective anti-PEG antibodies. | Q34223906 | ||
High affinity humanized antibodies without making hybridomas; immunization paired with mammalian cell display and in vitro somatic hypermutation | Q34482369 | ||
Coupling recombinase-mediated cassette exchange with somatic hypermutation for antibody affinity maturation in CHO cells. | Q51741733 | ||
Somatic hypermutation in B cells: an optimal control treatment. | Q52390653 | ||
Somatic hypermutation of immunoglobulin genes is linked to transcription initiation | Q70934062 | ||
Affinity maturation and hypermutation in a simulation of the humoral immune response | Q71118314 | ||
Stages of germinal center transit are defined by B cell transcription factor coexpression and relative abundance | Q79326749 | ||
Efficient production of Cre-mediated site-directed recombinants through the utilization of the puromycin resistance gene, pac: a transient gene-integration marker for ES cells | Q34651786 | ||
Mammalian cell display and somatic hypermutation in vitro for human antibody discovery | Q34974395 | ||
Vectors bicistronically linking a gene of interest to the SV40 large T antigen in combination with the SV40 origin of replication enhance transient protein expression and luciferase reporter activity | Q35184622 | ||
AIDing antibody diversity by error-prone mismatch repair | Q36173942 | ||
Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin | Q36355399 | ||
Clusters of Multiple Mutations: Incidence and Molecular Mechanisms | Q36455998 | ||
Germinal-center organization and cellular dynamics | Q36459345 | ||
Protein evolution by hypermutation and selection in the B cell line DT40 | Q36471434 | ||
Regulation of activation-induced cytidine deaminase DNA deamination activity in B-cells by Ser38 phosphorylation | Q36519034 | ||
Antibody diversification caused by disrupted mismatch repair and promiscuous DNA polymerases | Q36540495 | ||
The biochemistry of somatic hypermutation | Q37096080 | ||
Evolution of new nonantibody proteins via iterative somatic hypermutation. | Q37627375 | ||
Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination | Q37659903 | ||
Protein engineering: a new frontier for biological therapeutics | Q38286271 | ||
APOBEC3 genes: retroviral restriction factors to cancer drivers | Q38395120 | ||
Protein engineering approaches to chemical biotechnology | Q38927933 | ||
A prevalent cancer susceptibility APOBEC3A hybrid allele bearing APOBEC3B 3'UTR enhances chromosomal DNA damage | Q38949554 | ||
Directed evolution of green fluorescent protein by a new versatile PCR strategy for site-directed and semi-random mutagenesis | Q39572601 | ||
Mutation drift and repertoire shift in the maturation of the immune response | Q39658890 | ||
Evolutionary and somatic selection of the antibody repertoire in the mouse. | Q39682090 | ||
Mobilization of giant piggyBac transposons in the mouse genome | Q39826562 | ||
An ex vivo method for rapid generation of monoclonal antibodies (ADLib system). | Q40150041 | ||
AID mutates a non-immunoglobulin transgene independent of chromosomal position. | Q40303704 | ||
Induction of somatic hypermutation is associated with modifications in immunoglobulin variable region chromatin | Q40625542 | ||
Generation and iterative affinity maturation of antibodies in vitro using hypermutating B-cell lines | Q40697370 | ||
Increased transcription levels induce higher mutation rates in a hypermutating cell line | Q40814374 | ||
AID upmutants isolated using a high-throughput screen highlight the immunity/cancer balance limiting DNA deaminase activity | Q40818553 | ||
High-throughput mutagenesis using a two-fragment PCR approach | Q42339240 | ||
AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts | Q42813803 | ||
Simultaneous surface display and secretion of proteins from mammalian cells facilitate efficient in vitro selection and maturation of antibodies | Q43097910 | ||
Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation | Q44486460 | ||
Modern methods for laboratory diversification of biomolecules | Q47387337 | ||
Somatic hypermutation in the heavy chain locus correlates with transcription | Q47713194 | ||
Clustered Mutation Signatures Reveal that Error-Prone DNA Repair Targets Mutations to Active Genes | Q48016992 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 9413 | |
P577 | publication date | 2018-06-20 | |
P1433 | published in | Scientific Reports | Q2261792 |
P1476 | title | Transient AID expression for in situ mutagenesis with improved cellular fitness. | |
P478 | volume | 8 |
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