Affinity maturation and hypermutation in a simulation of the humoral immune response

scientific article published on 01 June 1996

Affinity maturation and hypermutation in a simulation of the humoral immune response is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/EJI.1830260626
P698PubMed publication ID8647216

P2093author name stringCelada F
Seiden PE
P2860cites workKinetic and affinity limits on antibodies produced during immune responsesQ34598643
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The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary responseQ36354168
Antigen-driven B cell differentiation in vivoQ36361955
The efficiency of antibody affinity maturation: can the rate of B-cell division be limiting?Q37953676
Evolutionary and somatic selection of the antibody repertoire in the mouse.Q39682090
Cell Selection by Antigen in the Immune ResponseQ39985236
The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacementQ40626080
Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genesQ40858318
Cyclic re-entry of germinal center B cells and the efficiency of affinity maturationQ40858324
A model for simulating cognate recognition and response in the immune systemQ41105464
Domain association in immunoglobulin molecules. The packing of variable domainsQ44715886
Somatic hypermutation in B cells: an optimal control treatment.Q52390653
Maturation of the humoral immune response as an optimization problemQ52443852
Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.Q54608320
Modelling thymic functions in a cellular automatonQ71714654
Hypermutation generating the sheep immunoglobulin repertoire is an antigen-independent processQ72388464
VARIATIONS IN AFFINITIES OF ANTIBODIES DURING THE IMMUNE RESPONSEQ76969494
P433issue6
P304page(s)1350-1358
P577publication date1996-06-01
P1433published inEuropean Journal of ImmunologyQ5412727
P1476titleAffinity maturation and hypermutation in a simulation of the humoral immune response
P478volume26

Reverse relations

cites work (P2860)
Q59657060A high performance simulator of the immune response
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