scholarly article | Q13442814 |
P819 | ADS bibcode | 2014PNAS..111E.988Z |
P356 | DOI | 10.1073/PNAS.1320486111 |
P932 | PMC publication ID | 3964074 |
P698 | PubMed publication ID | 24591601 |
P5875 | ResearchGate publication ID | 260486621 |
P50 | author | Javier M Di Noia | Q58227120 |
Stephen P Methot | Q59599651 | ||
Anne Durandy | Q42348498 | ||
P2093 | author name string | Kohsuke Imai | |
Paul Foster | |||
Mani Larijani | |||
Anne-Marie Patenaude | |||
Heather Fifield | |||
Anil K Eranki | |||
Ramiro E Verdun | |||
Astrid Zahn | |||
Elena M Cortizas | |||
P2860 | cites work | Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2) | Q24290325 |
Human CtIP promotes DNA end resection | Q24646062 | ||
Activation-induced cytidine deaminase initiates immunoglobulin gene conversion and hypermutation by a common intermediate | Q24802780 | ||
AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification | Q28208979 | ||
Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig Loci in activated B cells | Q42630118 | ||
AID mutant analyses indicate requirement for class-switch-specific cofactors | Q42798287 | ||
AID is required for c-myc/IgH chromosome translocations in vivo | Q45021537 | ||
Differences in the enzymatic efficiency of human and bony fish AID are mediated by a single residue in the C terminus modulating single-stranded DNA binding | Q45167924 | ||
AID constrains germinal center size by rendering B cells susceptible to apoptosis. | Q45991820 | ||
Analysis of class switch recombination and somatic hypermutation in patients affected with autosomal dominant hyper-IgM syndrome type 2. | Q46490209 | ||
RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination | Q47765927 | ||
Alternative end-joining and classical nonhomologous end-joining pathways repair different types of double-strand breaks during class-switch recombination. | Q53085728 | ||
Rag mutations reveal robust alternative end joining | Q59098597 | ||
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis | Q28274000 | ||
AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching | Q28366125 | ||
Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation | Q28586304 | ||
53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination. | Q29465548 | ||
Clinical, immunologic and genetic analysis of 29 patients with autosomal recessive hyper-IgM syndrome due to Activation-Induced Cytidine Deaminase deficiency | Q33359560 | ||
Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4. | Q33656097 | ||
53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination | Q33794964 | ||
The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia | Q34099472 | ||
Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis | Q34303405 | ||
Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90. | Q34340626 | ||
Impaired induction of DNA lesions during immunoglobulin class-switch recombination in humans influences end-joining repair | Q34438294 | ||
RPA accumulation during class switch recombination represents 5'-3' DNA-end resection during the S-G2/M phase of the cell cycle | Q34537165 | ||
The AID-induced DNA damage response in chromatin | Q34715036 | ||
Mechanism and regulation of class switch recombination | Q34764888 | ||
The RAG2 C terminus suppresses genomic instability and lymphomagenesis | Q35216006 | ||
REG-γ associates with and modulates the abundance of nuclear activation-induced deaminase | Q35669089 | ||
A structural basis for the biochemical behavior of activation-induced deoxycytidine deaminase class-switch recombination-defective hyper-IgM-2 mutants | Q36201805 | ||
CtIP promotes microhomology-mediated alternative end joining during class-switch recombination | Q36316904 | ||
AID from bony fish catalyzes class switch recombination | Q36403021 | ||
Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching | Q36547669 | ||
Pathophysiology of B-cell intrinsic immunoglobulin class switch recombination deficiencies | Q36845690 | ||
The biochemistry of somatic hypermutation | Q37096080 | ||
The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination | Q37115233 | ||
S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase | Q37164427 | ||
A portable hot spot recognition loop transfers sequence preferences from APOBEC family members to activation-induced cytidine deaminase. | Q37371679 | ||
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion | Q37587676 | ||
A DNA break- and phosphorylation-dependent positive feedback loop promotes immunoglobulin class-switch recombination. | Q37733531 | ||
Classical and alternative end-joining pathways for repair of lymphocyte-specific and general DNA double-strand breaks | Q38051860 | ||
14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination. | Q39664674 | ||
Antibody class switching mediated by yeast endonuclease-generated DNA breaks. | Q40196054 | ||
The double-edged sword of activation-induced cytidine deaminase. | Q40474265 | ||
C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion. | Q40627624 | ||
AID upmutants isolated using a high-throughput screen highlight the immunity/cancer balance limiting DNA deaminase activity | Q40818553 | ||
Clonal selection and learning in the antibody system | Q41002744 | ||
Active nuclear import and cytoplasmic retention of activation-induced deaminase | Q41792388 | ||
AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected]. | Q41870415 | ||
AID associates with single-stranded DNA with high affinity and a long complex half-life in a sequence-independent manner. | Q42101206 | ||
Separation of function between isotype switching and affinity maturation in vivo during acute immune responses and circulating autoantibodies in UNG-deficient mice | Q42438365 | ||
P433 | issue | 11 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | E988-97 | |
P577 | publication date | 2014-03-03 | |
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination | |
P478 | volume | 111 |
Q52723490 | A licensing step links AID to transcription elongation for mutagenesis in B cells. |
Q41995688 | AID Biology: A pathological and clinical perspective |
Q57292354 | AIMP3 Deletion Induces Acute Radiation Syndrome-like Phenotype in Mice |
Q36304376 | Activation-Induced Cytidine Deaminase Expression in Human B Cell Precursors Is Essential for Central B Cell Tolerance |
Q40090064 | Activation-induced cytidine deaminase targets SUV4-20-mediated histone H4K20 trimethylation to class-switch recombination sites |
Q35768862 | Cell Cycle Regulates Nuclear Stability of AID and Determines the Cellular Response to AID. |
Q38982117 | Chromatin reader Brd4 functions in Ig class switching as a repair complex adaptor of nonhomologous end-joining |
Q35289306 | Consecutive interactions with HSP90 and eEF1A underlie a functional maturation and storage pathway of AID in the cytoplasm. |
Q90057553 | Current insights into the mechanism of mammalian immunoglobulin class switch recombination |
Q37395827 | Decreased somatic hypermutation induces an impaired peripheral B cell tolerance checkpoint |
Q47404983 | Depletion of recombination-specific cofactors by the C-terminal mutant of the activation-induced cytidine deaminase causes the dominant negative effect on class switch recombination |
Q36710679 | Functional requirements of AID's higher order structures and their interaction with RNA-binding proteins |
Q35590309 | Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase |
Q27001131 | IgH chain class switch recombination: mechanism and regulation |
Q40926418 | Increased serum IgM, immunodeficiency, and autoimmunity: A clinical series |
Q35744148 | Individual substitution mutations in the AID C terminus that ablate IgH class switch recombination |
Q48256770 | Main steps in DNA double-strand break repair: an introduction to homologous recombination and related processes. |
Q42837072 | Mismatch repair proteins and AID activity are required for the dominant negative function of C-terminally deleted AID in class switching |
Q40093841 | Molecular characterization of AID-mediated reduction of hepatitis B virus transcripts |
Q39077274 | RNA Exosome and Non-coding RNA-Coupled Mechanisms in AID-Mediated Genomic Alterations |
Q36955793 | The SAGA Deubiquitination Module Promotes DNA Repair and Class Switch Recombination through ATM and DNAPK-Mediated γH2AX Formation. |
Q55491385 | Transient AID expression for in situ mutagenesis with improved cellular fitness. |
Q37346703 | UNG protects B cells from AID-induced telomere loss. |
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