| scholarly article | Q13442814 |
| P356 | DOI | 10.1038/88732 |
| P698 | PubMed publication ID | 11376340 |
| P50 | author | Igor B. Rogozin | Q45324573 |
| P2093 | author name string | Matsuda T | |
| Kunkel TA | |||
| Bebenek K | |||
| Pavlov YI | |||
| P2860 | cites work | hRAD30 mutations in the variant form of xeroderma pigmentosum | Q22010237 |
| The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta | Q28115711 | ||
| DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes | Q28190856 | ||
| Use of mutation spectra analysis software. | Q30327814 | ||
| Towards an understanding of somatic hypermutation | Q32067279 | ||
| Somatic hypermutation and the three R's: repair, replication and recombination | Q33545735 | ||
| The expanding polymerase universe | Q34186298 | ||
| Modifying the sequence of an immunoglobulin V-gene alters the resulting pattern of hypermutation | Q35939989 | ||
| Somatic mutation of immunoglobulin lambda chains: a segment of the major intron hypermutates as much as the complementarity-determining regions | Q35994757 | ||
| The many faces of DNA polymerases: strategies for mutagenesis and for mutational avoidance | Q36099918 | ||
| Bridging the gap: a family of novel DNA polymerases that replicate faulty DNA. | Q36182449 | ||
| Both DNA strands of antibody genes are hypermutation targets | Q36220380 | ||
| Analysis of somatic mutations in kappa transgenes | Q36352010 | ||
| Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene | Q36354162 | ||
| Error-prone candidates vie for somatic mutation | Q36368573 | ||
| The role of DNA repair in somatic hypermutation of immunoglobulin genes | Q36400909 | ||
| A hypermutable insert in an immunoglobulin transgene contains hotspots of somatic mutation and sequences predicting highly stable structures in the RNA transcript | Q36404086 | ||
| Analysis of somatic hypermutation in mouse Peyer's patches using immunoglobulin kappa light-chain transgenes | Q36618119 | ||
| Defect in IgV gene somatic hypermutation in common variable immuno-deficiency syndrome | Q36639355 | ||
| Somatic diversification of chicken immunoglobulin light chains by point mutations | Q37740428 | ||
| Mutation drift and repertoire shift in the maturation of the immune response | Q39658890 | ||
| Somatic hypermutation | Q40404787 | ||
| Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes | Q40840741 | ||
| Clonal selection and learning in the antibody system | Q41002744 | ||
| Somatic hypermutagenesis in immunoglobulin genes. I. Correlation between somatic mutations and repeats. Somatic mutation properties and clonal selection | Q41893302 | ||
| Distribution of mutations around rearranged heavy-chain antibody variable-region genes | Q41966971 | ||
| Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis | Q43586184 | ||
| Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene | Q45345090 | ||
| Critical test of hot spot motifs for immunoglobulin hypermutation | Q46452104 | ||
| Mutation, selection, and memory in B lymphocytes of exothermic vertebrates | Q46898159 | ||
| The 5' boundary of somatic hypermutation in a V kappa gene is in the leader intron | Q48081907 | ||
| Low fidelity DNA synthesis by human DNA polymerase-eta | Q50335566 | ||
| The subclass approach for mutational spectrum analysis: application of the SEM algorithm. | Q52239120 | ||
| DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation | Q57198273 | ||
| The Targeting of Somatic Hypermutation Closely Resembles That of Meiotic Mutation | Q57234192 | ||
| Somatic hypermutagenesis in immunoglobulin genes. III. Somatic mutations in the chicken light chain locus | Q58003468 | ||
| Pecularities of immunoglobulin gene structures as a basis for somatic mutation emergence | Q58003511 | ||
| Origin of Antibody Variation | Q59057486 | ||
| Codon bias targets mutation. | Q59081204 | ||
| Hypermutation generating the sheep immunoglobulin repertoire is an antigen-independent process | Q72388464 | ||
| Somatic hypermutation of VkappaJkappa rearrangements: targeting of RGYW motifs on both DNA strands and preferential selection of mutated codons within RGYW motifs | Q73281807 | ||
| Proofreading of DNA polymerase eta-dependent replication errors | Q73288765 | ||
| Multiple sequences from downstream of the J kappa cluster can combine to recruit somatic hypermutation to a heterologous, upstream mutation domain | Q74251724 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 530-536 | |
| P577 | publication date | 2001-06-01 | |
| P1433 | published in | Nature Immunology | Q1071725 |
| P1476 | title | Somatic mutation hotspots correlate with DNA polymerase eta error spectrum. | |
| P478 | volume | 2 |
| Q28587504 | 129-derived strains of mice are deficient in DNA polymerase iota and have normal immunoglobulin hypermutation |
| Q53250439 | A model of liver carcinogenesis originating from hepatic progenitor cells with accumulation of genetic alterations. |
| Q37406038 | A real-time fluorescence method for enzymatic characterization of specialized human DNA polymerases |
| Q33346216 | A regulatory role for NBS1 in strand-specific mutagenesis during somatic hypermutation |
| Q36211150 | A role for the MutL mismatch repair Mlh3 protein in immunoglobulin class switch DNA recombination and somatic hypermutation |
| Q24318524 | A unique error signature for human DNA polymerase nu |
| Q28590572 | ADAR1 protein induces adenosine-targeted DNA mutations in senescent Bcl6 gene-deficient cells |
| Q34770418 | AID and mismatch repair in antibody diversification |
| Q28208979 | AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification |
| Q24531345 | AID-GFP chimeric protein increases hypermutation of Ig genes with no evidence of nuclear localization |
| Q36845671 | AID-initiated purposeful mutations in immunoglobulin genes |
| Q40463112 | ASFV DNA polymerse X is extremely error-prone under diverse assay conditions and within multiple DNA sequence contexts |
| Q36399387 | Absence of DNA polymerase eta reveals targeting of C mutations on the nontranscribed strand in immunoglobulin switch regions |
| Q36214679 | Activation induced deaminase mutational signature overlaps with CpG methylation sites in follicular lymphoma and other cancers |
| Q57112529 | Activation-induced cytidine deaminase (AID) is strongly expressed in the fetal bovine ileal Peyer's patch and spleen and is associated with expansion of the primary antibody repertoire in the absence of exogenous antigens |
| Q24683335 | Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase |
| Q28217205 | Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas |
| Q40566152 | Activation-induced cytosine deaminase (AID) is actively exported out of the nucleus but retained by the induction of DNA breaks |
| Q42944652 | Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutation |
| Q33299999 | Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA. |
| Q35980902 | Altered Ig hypermutation pattern and frequency in complementary mouse models of DNA polymerase ζ activity |
| Q57540787 | Altered spectrum of somatic hypermutation in common variable immunodeficiency disease characteristic of defective repair of mutations |
| Q27666908 | An Insertion Mutation That Distorts Antibody Binding Site Architecture Enhances Function of a Human Antibody |
| Q37162837 | Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting. |
| Q91808144 | Antibody Structure and Function: The Basis for Engineering Therapeutics |
| Q36540495 | Antibody diversification caused by disrupted mismatch repair and promiscuous DNA polymerases |
| Q58781552 | Beyond Hot Spots: Biases in Antibody Somatic Hypermutation and Implications for Vaccine Design |
| Q40329923 | Biased dA/dT somatic hypermutation as regulated by the heavy chain intronic iEmu enhancer and 3'Ealpha enhancers in human lymphoblastoid B cells |
| Q28538764 | Biochemical analysis of DNA polymerase η fidelity in the presence of replication protein A |
| Q36893377 | Biochemical analysis of active site mutations of human polymerase η |
| Q35978838 | Cellular functions of DNA polymerase zeta and Rev1 protein |
| Q36082102 | Cerebrospinal fluid B cells from multiple sclerosis patients are subject to normal germinal center selection. |
| Q36984106 | Characterization of Ig gene somatic hypermutation in the absence of activation-induced cytidine deaminase |
| Q40783328 | Clonal instability of V region hypermutation in the Ramos Burkitt's lymphoma cell line |
| Q34090613 | Clustered and genome-wide transient mutagenesis in human cancers: Hypermutation without permanent mutators or loss of fitness |
| Q35992079 | Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions. |
| Q36455998 | Clusters of Multiple Mutations: Incidence and Molecular Mechanisms |
| Q36581740 | Codon insertion and deletion functions as a somatic diversification mechanism in human antibody repertoires |
| Q53288810 | Comparative analysis of germline and somatic microlesion mutational spectra in 17 human tumor suppressor genes. |
| Q34761620 | Comparative mutational analyses of influenza A viruses |
| Q34289810 | Context of deletions and insertions in human coding sequences. |
| Q24293055 | Controlling the subcellular localization of DNA polymerases iota and eta via interactions with ubiquitin |
| Q34098247 | Correlation of somatic hypermutation specificity and A-T base pair substitution errors by DNA polymerase eta during copying of a mouse immunoglobulin kappa light chain transgene. |
| Q36015019 | DNA deamination in immunity |
| Q42944715 | DNA double-strand breaks: prior to but not sufficient in targeting hypermutation |
| Q36193082 | DNA lesions and repair in immunoglobulin class switch recombination and somatic hypermutation |
| Q54799136 | DNA polymerase eta is a limiting factor for A:T mutations in Ig genes and contributes to antibody affinity maturation. |
| Q28190856 | DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes |
| Q28506592 | DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes |
| Q46665792 | DNA polymerase η mutational signatures are found in a variety of different types of cancer |
| Q34360690 | DNA polymerases and somatic hypermutation of immunoglobulin genes |
| Q35978843 | DNA polymerases eta and iota |
| Q73934002 | DNA polymerases in immunity: profiting from errors |
| Q37724828 | DNA polymerases β and λ do not directly affect Ig variable region somatic hypermutation although their absence reduces the frequency of mutations |
| Q42937091 | Dependence of nucleotide substitutions on Ung2, Msh2, and PCNA-Ub during somatic hypermutation. |
| Q33853914 | Different mutation signatures in DNA polymerase eta- and MSH6-deficient mice suggest separate roles in antibody diversification |
| Q41892816 | Disparate roles of ATR and ATM in immunoglobulin class switch recombination and somatic hypermutation |
| Q52717520 | Diverse roles of RAD18 and Y-family DNA polymerases in tumorigenesis. |
| Q44203468 | Does activation-induced deaminase initiate antibody diversification by DNA deamination? |
| Q64387942 | Double-strand breaks in DNA during somatic hypermutation of Ig genes: cause or consequence? |
| Q57251009 | Ectopic GC in the thymus of myasthenia gravis patients show characteristics of normal GC |
| Q57307991 | Effects of Sequence and Structure on the Hypermutability of Immunoglobulin Genes |
| Q35147024 | Efficient Genome-Wide Detection and Cataloging of EMS-Induced Mutations Using Exome Capture and Next-Generation Sequencing |
| Q33963905 | Emergence and evolution of functional heavy-chain antibodies in Camelidae |
| Q34572184 | Emerging links between hypermutation of antibody genes and DNA polymerases |
| Q36389685 | Evaluation of molecular models for the affinity maturation of antibodies: roles of cytosine deamination by AID and DNA repair |
| Q37342726 | Evaluation of the Antigen-Experienced B-Cell Receptor Repertoire in Healthy Children and Adults |
| Q35768284 | Evidence for preferential Ig gene usage and differential TdT and exonuclease activities in human naïve and memory B cells |
| Q33283188 | Evolution and diversification of lamprey antigen receptors: evidence for involvement of an AID-APOBEC family cytosine deaminase |
| Q34297067 | Evolving responsively: adaptive mutation |
| Q24814190 | Expression of human AID in yeast induces mutations in context similar to the context of somatic hypermutation at G-C pairs in immunoglobulin genes |
| Q33703002 | Fanca deficiency reduces A/T transitions in somatic hypermutation and alters class switch recombination junctions in mouse B cells. |
| Q35047056 | Functions of human DNA polymerases eta, kappa and iota suggested by their properties, including fidelity with undamaged DNA templates. |
| Q33690522 | Generation and repair of AID-initiated DNA lesions in B lymphocytes |
| Q34310757 | Genesis of the strand-biased signature in somatic hypermutation of rearranged immunoglobulin variable genes |
| Q34341934 | Genome-wide detection of genes targeted by non-Ig somatic hypermutation in lymphoma |
| Q35731798 | Germinal center-associated nuclear protein contributes to affinity maturation of B cell antigen receptor in T cell-dependent responses. |
| Q36370913 | H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation |
| Q33455585 | High mutability of the tumor suppressor genes RASSF1 and RBSP3 (CTDSPL) in cancer |
| Q42630555 | High-risk follicular lymphomas harbour more somatic mutations including those in the AID-motif |
| Q39600750 | Human DNA polymerase mu (Pol mu) exhibits an unusual replication slippage ability at AAF lesion |
| Q34310763 | Human DNA polymerase-eta, an A-T mutator in somatic hypermutation of rearranged immunoglobulin genes, is a reverse transcriptase |
| Q34360486 | Human genetic defects in class-switch recombination (hyper-IgM syndromes). |
| Q43244319 | Hypermutation at A/T sites during G.U mismatch repair in vitro by human B-cell lysates |
| Q28255066 | Hypermutation in human cancer genomes: footprints and mechanisms |
| Q95300387 | Hypermutation in single-stranded DNA |
| Q30351902 | Hypothesis driven single nucleotide polymorphism search (HyDn-SNP-S). |
| Q37164431 | Identification of murine B cell lines that undergo somatic hypermutation focused to A:T and G:C residues |
| Q42972358 | Identifying protein-protein interactions in somatic hypermutation |
| Q34700410 | Ig gene hypermutation: a mechanism is due. |
| Q42384358 | Immunoglobulin heavy and light chain gene features are correlated with primary cold agglutinin disease onset and activity |
| Q35213276 | Immunoglobulin somatic hypermutation: double-strand DNA breaks, AID and error-prone DNA repair |
| Q34197279 | Imprint of somatic hypermutation differs in human immunoglobulin heavy and lambda chain variable gene segments |
| Q34157224 | Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota. |
| Q64079637 | Inferred Allelic Variants of Immunoglobulin Receptor Genes: A System for Their Evaluation, Documentation, and Naming |
| Q37138006 | Interference of mismatch and base excision repair during the processing of adjacent U/G mispairs may play a key role in somatic hypermutation |
| Q36597287 | Interplay between Target Sequences and Repair Pathways Determines Distinct Outcomes of AID-Initiated Lesions |
| Q36403602 | Intricate targeting of immunoglobulin somatic hypermutation maximizes the efficiency of affinity maturation |
| Q34225193 | Kinetic analysis of the unique error signature of human DNA polymerase ν. |
| Q35792957 | Known components of the immunoglobulin A:T mutational machinery are intact in Burkitt lymphoma cell lines with G:C bias |
| Q36740110 | Low-fidelity DNA synthesis by human DNA polymerase theta. |
| Q37235387 | Low-fidelity DNA synthesis by the L979F mutator derivative of Saccharomyces cerevisiae DNA polymerase zeta. |
| Q34394298 | MSH2-MSH6 stimulates DNA polymerase eta, suggesting a role for A:T mutations in antibody genes |
| Q27324793 | MSH2/MSH6 complex promotes error-free repair of AID-induced dU:G mispairs as well as error-prone hypermutation of A:T sites |
| Q27677864 | Mechanism of somatic hypermutation at the WA motif by human DNA polymerase η. |
| Q48126233 | Microdeletions and microinsertions causing human genetic disease: common mechanisms of mutagenesis and the role of local DNA sequence complexity |
| Q28540820 | Microsatellite interruptions stabilize primate genomes and exist as population-specific single nucleotide polymorphisms within individual human genomes |
| Q30706182 | Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data |
| Q24530548 | Molecular analysis of mutations in DNA polymerase eta in xeroderma pigmentosum-variant patients |
| Q34542246 | Molecular mechanism of class switch recombination: linkage with somatic hypermutation |
| Q33553746 | Molecular signatures of hemagglutinin stem-directed heterosubtypic human neutralizing antibodies against influenza A viruses |
| Q28586272 | Msh2 ATPase activity is essential for somatic hypermutation at a-T basepairs and for efficient class switch recombination |
| Q64102292 | Mutating for Good: DNA Damage Responses During Somatic Hypermutation |
| Q33997247 | Mutation of the little finger domain in human DNA polymerase η alters fidelity when copying undamaged DNA |
| Q34012361 | Mutational fingerprints of aging |
| Q25257243 | Mutational hotspots in the TP53 gene and, possibly, other tumor suppressors evolve by positive selection |
| Q55060101 | Mutational signatures and mutable motifs in cancer genomes. |
| Q24536098 | Mutations in human DNA polymerase eta motif II alter bypass of DNA lesions |
| Q37532179 | Mutator effects and mutation signatures of editing deaminases produced in bacteria and yeast. |
| Q34919969 | Mutator phenotypes due to DNA replication infidelity. |
| Q35953749 | On the molecular mechanism of somatic hypermutation of rearranged immunoglobulin genes |
| Q40405554 | Overexpression of human DNA polymerase mu (Pol mu) in a Burkitt's lymphoma cell line affects the somatic hypermutation rate |
| Q28586777 | Polymerase mu is up-regulated during the T cell-dependent immune response and its deficiency alters developmental dynamics of spleen centroblasts |
| Q44486460 | Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation |
| Q33916814 | Prognostic B-cell signatures using mRNA-seq in patients with subtype-specific breast and ovarian cancer |
| Q91960739 | Rapid and Focused Maturation of a VRC01-Class HIV Broadly Neutralizing Antibody Lineage Involves Both Binding and Accommodation of the N276-Glycan |
| Q36557058 | Regulation of AID, the B-cell genome mutator |
| Q90050600 | Repertoire Sequencing of B Cells Elucidates the Role of UNG and Mismatch Repair Proteins in Somatic Hypermutation in Humans |
| Q47108323 | Reverse Transcriptase Mechanism of Somatic Hypermutation: 60 Years of Clonal Selection Theory |
| Q29346764 | Role of Pseudomonas aeruginosa dinB-encoded DNA polymerase IV in mutagenesis |
| Q33591714 | Role of the translocation partner in protection against AID-dependent chromosomal translocations |
| Q36687824 | Roles of DNA polymerases in replication, repair, and recombination in eukaryotes. |
| Q36984836 | SOCS1 mutation subtypes predict divergent outcomes in diffuse large B-Cell lymphoma (DLBCL) patients |
| Q44356424 | Sequence context at human single nucleotide polymorphisms: overrepresentation of CpG dinucleotide at polymorphic sites and suppression of variation in CpG islands |
| Q40118226 | Sequence intrinsic somatic mutation mechanisms contribute to affinity maturation of VRC01-class HIV-1 broadly neutralizing antibodies |
| Q77090699 | Smaller role for pol eta? |
| Q60370453 | Somatic Hypermutation of Ig Genes is Affected Differently by Failures in Apoptosis Caused by Disruption of Fas (lpr Mutation) or by Overexpression of Bcl-2 |
| Q45248977 | Somatic hypermutation at A.T pairs: polymerase error versus dUTP incorporation. |
| Q34516540 | Somatic hypermutation in human B cell subsets |
| Q36399510 | Somatic hypermutation is limited by CRM1-dependent nuclear export of activation-induced deaminase |
| Q52583325 | Somatic hypermutation of T cell receptor α chain contributes to selection in nurse shark thymus. |
| Q24535846 | Somatic hypermutation of the AID transgene in B and non-B cells |
| Q42149724 | Somatic hypermutation targeting is influenced by location within the immunoglobulin V region |
| Q35978867 | Somatic hypermutation: a mutational panacea |
| Q36693193 | Somatic hypermutation: activation-induced deaminase for C/G followed by polymerase eta for A/T. |
| Q33384739 | Somatic hypermutations and isotype restricted exceptionally long CDR3H contribute to antibody diversification in cattle |
| Q34116350 | Somatic immunoglobulin hypermutation |
| Q57167354 | Somatic mutation load and spectra: A record of DNA damage and repair in healthy human cells |
| Q34420737 | Statistical inference of sequence-dependent mutation rates. |
| Q35763914 | Suppressor of cytokine signaling 1 gene mutation status as a prognostic biomarker in classical Hodgkin lymphoma. |
| Q30436370 | Temporal regulation of Ig gene diversification revealed by single-cell imaging |
| Q57178227 | The Bayesian optimist's guide to adaptive immune receptor repertoire analysis |
| Q86958025 | The V(H) repertoire and clonal diversification of B cells in inflammatory myopathies |
| Q54777328 | The absence of DNA polymerase kappa does not affect somatic hypermutation of the mouse immunoglobulin heavy chain gene. |
| Q37334051 | The concerted action of Msh2 and UNG stimulates somatic hypermutation at A . T base pairs |
| Q26801603 | The evolution within us |
| Q33662167 | The protein-protein interface evolution acts in a similar way to antibody affinity maturation. |
| Q42467404 | The role of DNA polymerase alpha in the control of mutagenesis in Saccharomyces cerevisiae cells starved for nutrients |
| Q38041514 | The role of activation-induced deaminase in antibody diversification and genomic instability |
| Q36403120 | The very 5' end and the constant region of Ig genes are spared from somatic mutation because AID does not access these regions |
| Q34218124 | Theoretical analysis of mutation hotspots and their DNA sequence context specificity |
| Q28190690 | Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand |
| Q37061670 | Transcriptional pausing and stalling causes multiple clustered mutations by human activation-induced deaminase |
| Q34356338 | Translesion DNA polymerases |
| Q39171293 | Translesion DNA polymerases in eukaryotes: what makes them tick? |
| Q36945144 | Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression |
| Q27935855 | Unique error signature of the four-subunit yeast DNA polymerase epsilon |
| Q33756190 | Variations on a theme: eukaryotic Y-family DNA polymerases |
| Q24309639 | Werner syndrome protein interacts functionally with translesion DNA polymerases |
| Q35164207 | What role for AID: mutator, or assembler of the immunoglobulin mutasome? |
Search more.