scholarly article | Q13442814 |
P50 | author | David A. Hafler | Q25004567 |
Gur Yaari | Q41050662 | ||
P2093 | author name string | Namita Gupta | |
Francois Vigneault | |||
Mohamed Uduman | |||
Steven H Kleinstein | |||
Kevin C O'Connor | |||
Joel N H Stern | |||
Uri Laserson | |||
Daniel Gadala-Maria | |||
Jason A Vander Heiden | |||
P2860 | cites work | Estimating Hypermutation Rates from Clonal Tree Data | Q30882543 |
Cutting edge: DGYW/WRCH is a better predictor of mutability at G:C bases in Ig hypermutation than the widely accepted RGYW/WRCY motif and probably reflects a two-step activation-induced cytidine deaminase-triggered process | Q33198930 | ||
Compartmentalized linkage of genes encoding interacting protein pairs. | Q33832538 | ||
IMGT unique numbering for immunoglobulin and T cell receptor variable domains and Ig superfamily V-like domains | Q34164031 | ||
Quantifying selection in high-throughput Immunoglobulin sequencing data sets | Q34284964 | ||
Detecting selection in immunoglobulin sequences | Q35075665 | ||
Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots | Q36172034 | ||
AIDing antibody diversity by error-prone mismatch repair | Q36173942 | ||
Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin | Q36261566 | ||
The biochemistry of somatic hypermutation | Q37096080 | ||
V-region mutation in vitro, in vivo, and in silico reveal the importance of the enzymatic properties of AID and the sequence environment | Q37193388 | ||
Biochemical analysis of hypermutational targeting by wild type and mutant activation-induced cytidine deaminase | Q40515192 | ||
Clone: a Monte-Carlo computer simulation of B cell clonal expansion, somatic mutation, and antigen-driven selection | Q41711157 | ||
Somatic hypermutation targeting is influenced by location within the immunoglobulin V region | Q42149724 | ||
Paratome: an online tool for systematic identification of antigen-binding regions in antibodies based on sequence or structure | Q42232982 | ||
Predicting regional mutability in antibody V genes based solely on di- and trinucleotide sequence composition | Q42604426 | ||
Di- and trinucleotide target preferences of somatic mutagenesis in normal and autoreactive B cells | Q42637489 | ||
The nucleotide-replacement spectrum under somatic hypermutation exhibits microsequence dependence that is strand-symmetric and distinct from that under germline mutation | Q44872484 | ||
Hypermutation at A-T base pairs: the A nucleotide replacement spectrum is affected by adjacent nucleotides and there is no reverse complementarity of sequences flanking mutated A and T nucleotides. | Q46740213 | ||
Sequence-specific targeting of two bases on both DNA strands by the somatic hypermutation mechanism | Q47660823 | ||
The microenvironment of germ cell tumors harbors a prominent antigen-driven humoral response | Q48071040 | ||
Accurate estimation of substitution rates with neighbor-dependent models in a phylogenetic context. | Q51423936 | ||
IgTree: creating Immunoglobulin variable region gene lineage trees. | Q51871158 | ||
Problems in using statistical analysis of replacement and silent mutations in antibody genes for determining antigen-driven affinity selection. | Q52992155 | ||
Somatic mutation hotspots correlate with DNA polymerase eta error spectrum. | Q55034838 | ||
The Targeting of Somatic Hypermutation Closely Resembles That of Meiotic Mutation | Q57234192 | ||
Characteristics of sequences around individual nucleotide substitutions in IgVH genes suggest different GC and AT mutators | Q77823529 | ||
P304 | page(s) | 358 | |
P577 | publication date | 2013-11-15 | |
P1433 | published in | Frontiers in Immunology | Q27723748 |
P1476 | title | Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data | |
P478 | volume | 4 |
Q52597630 | 5' Rapid Amplification of cDNA Ends and Illumina MiSeq Reveals B Cell Receptor Features in Healthy Adults, Adults With Chronic HIV-1 Infection, Cord Blood, and Humanized Mice. |
Q31135078 | A Model of Somatic Hypermutation Targeting in Mice Based on High-Throughput Ig Sequencing Data |
Q41996650 | A Phylogenetic Codon Substitution Model for Antibody Lineages |
Q92454312 | A review of canine B cell clonality assays and primer set optimization using large-scale repertoire data |
Q36349113 | Antigen Receptor Galaxy: A User-Friendly, Web-Based Tool for Analysis and Visualization of T and B Cell Receptor Repertoire Data |
Q56376231 | Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope |
Q28640605 | Assigning and visualizing germline genes in antibody repertoires |
Q30891515 | Automated analysis of high-throughput B-cell sequencing data reveals a high frequency of novel immunoglobulin V gene segment alleles |
Q35155724 | B cell variable genes have evolved their codon usage to focus the targeted patterns of somatic mutation on the complementarity determining regions |
Q59133570 | Benchmarking Tree and Ancestral Sequence Inference for B Cell Receptor Sequences |
Q58781552 | Beyond Hot Spots: Biases in Antibody Somatic Hypermutation and Implications for Vaccine Design |
Q30970597 | Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data |
Q50420437 | Computational Strategies for Dissecting the High-Dimensional Complexity of Adaptive Immune Repertoires |
Q64091957 | DSab-origin: a novel IGHD sensitive VDJ mapping method and its application on antibody response after influenza vaccination |
Q47754080 | Dynamics of the human antibody repertoire after B cell depletion in systemic sclerosis. |
Q48352173 | Dysregulation of B Cell Repertoire Formation in Myasthenia Gravis Patients Revealed through Deep Sequencing. |
Q36020766 | Effects of Darwinian Selection and Mutability on Rate of Broadly Neutralizing Antibody Evolution during HIV-1 Infection |
Q37342726 | Evaluation of the Antigen-Experienced B-Cell Receptor Repertoire in Healthy Children and Adults |
Q49860297 | Evidence for Alternate Modes of B cell Activation Involving Fab Acquired-N-Glycosylations in Antibody Secreting Cells Infiltrating the Labial Salivary Glands of Sjögren's Syndrome Patients |
Q92446647 | Exploiting B Cell Receptor Analyses to Inform on HIV-1 Vaccination Strategies |
Q92827369 | Fierce Selection and Interference in B-Cell Repertoire Response to Chronic HIV-1 |
Q58610902 | Filtering Next-Generation Sequencing of the Ig Gene Repertoire Data Using Antibody Structural Information |
Q55356257 | Functional Relevance of Improbable Antibody Mutations for HIV Broadly Neutralizing Antibody Development. |
Q33654599 | Gene-Specific Substitution Profiles Describe the Types and Frequencies of Amino Acid Changes during Antibody Somatic Hypermutation |
Q52352265 | HIV envelope V3 region mimic embodies key features of a broadly neutralizing antibody lineage epitope. |
Q36274750 | Hierarchical Clustering Can Identify B Cell Clones with High Confidence in Ig Repertoire Sequencing Data. |
Q48297980 | High-Throughput Single-Cell Analysis of B Cell Receptor Usage among Autoantigen-Specific Plasma Cells in Celiac Disease. |
Q49187352 | High-throughput immune repertoire analysis with IGoR. |
Q42261577 | Human IgG2- and IgG4-expressing memory B cells display enhanced molecular and phenotypic signs of maturity and accumulate with age. |
Q59812460 | Identification of CVID Patients With Defects in Immune Repertoire Formation or Specification |
Q90239275 | Immune Profiling of Human Gut-Associated Lymphoid Tissue Identifies a Role for Isolated Lymphoid Follicles in Priming of Region-Specific Immunity |
Q41963347 | Immune system modeling and analysis. |
Q28640380 | Inferring processes underlying B-cell repertoire diversity |
Q31107783 | Integrating multiple immunogenetic data sources for feature extraction and mining somatic hypermutation patterns: the case of "towards analysis" in chronic lymphocytic leukaemia |
Q64066934 | Large-scale network analysis reveals the sequence space architecture of antibody repertoires |
Q57159578 | Local Clonal Diversification and Dissemination of B Lymphocytes in the Human Bronchial Mucosa |
Q36985671 | Long-lived antigen-induced IgM plasma cells demonstrate somatic mutations and contribute to long-term protection. |
Q36584038 | Neutralizing antibodies against West Nile virus identified directly from human B cells by single-cell analysis and next generation sequencing. |
Q38811964 | Oncogenic events rather than antigen selection pressure may be the main driving forces for relapse in diffuse large B-cell lymphomas |
Q40368519 | Phylogenetic analysis of the human antibody repertoire reveals quantitative signatures of immune senescence and aging |
Q28607156 | Practical guidelines for B-cell receptor repertoire sequencing analysis |
Q28640162 | Quantifying evolutionary constraints on B-cell affinity maturation |
Q46209629 | Reconstructing Antibody Repertoires from Error-Prone Immunosequencing Reads |
Q35685749 | Responsive population dynamics and wide seeding into the duodenal lamina propria of transglutaminase-2-specific plasma cells in celiac disease |
Q55003119 | Selection and Neutral Mutations Drive Pervasive Mutability Losses in Long-Lived Anti-HIV B-Cell Lineages. |
Q42667029 | Shared VH1-46 gene usage by pemphigus vulgaris autoantibodies indicates common humoral immune responses among patients. |
Q90335423 | Somatic hypermutation to counter a globally rare viral immunotype drove off-track antibodies in the CAP256-VRC26 HIV-1 V2-directed bNAb lineage |
Q58705788 | Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid tissue |
Q40290521 | Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies. |
Q41926663 | Stereotyped antibody responses target posttranslationally modified gluten in celiac disease |
Q57093739 | Structural Insights from HIV-Antibody Coevolution and Related Immunization Studies |
Q89759205 | Structural diversity of B-cell receptor repertoires along the B-cell differentiation axis in humans and mice |
Q38592595 | T-cell receptor profiling in cancer |
Q57178227 | The Bayesian optimist's guide to adaptive immune receptor repertoire analysis |
Q38708644 | The Diversity and Molecular Evolution of B-Cell Receptors during Infection |
Q36261329 | The Number of Overlapping AID Hotspots in Germline IGHV Genes Is Inversely Correlated with Mutation Frequency in Chronic Lymphocytic Leukemia |
Q64078703 | The Pipeline Repertoire for Ig-Seq Analysis |
Q42015134 | The mutation patterns in B-cell immunoglobulin receptors reflect the influence of selection acting at multiple time-scales |
Q36330081 | The preferred nucleotide contexts of the AID/APOBEC cytidine deaminases have differential effects when mutating retrotransposon and virus sequences compared to host genes |
Q58586481 | Tracing Antibody Repertoire Evolution by Systems Phylogeny |
Q96816315 | Ultrasensitive amplicon barcoding for next-generation sequencing facilitating sequence error and amplification-bias correction |
Q52688244 | Using Genotype Abundance to Improve Phylogenetic Inference. |
Q90644755 | VDJbase: an adaptive immune receptor genotype and haplotype database |
Q33807674 | pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires |