scholarly article | Q13442814 |
P50 | author | Barton Haynes | Q4865631 |
Mattia Bonsignori | Q56808332 | ||
David Easterhoff | Q89359808 | ||
Kevin Wiehe | Q89359811 | ||
Munir Alam | Q89520930 | ||
Wilton B Williams | Q89520935 | ||
P2093 | author name string | Thomas B Kepler | |
R Ryan Meyerhoff | |||
William J Faison | |||
Todd Bradley | |||
Kevin O Saunders | |||
Connor Hart | |||
P2860 | cites work | bNAber: database of broadly neutralizing HIV antibodies | Q24567758 |
Polyclonal B cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individuals | Q24635002 | ||
Related Mechanisms of Antibody Somatic Hypermutation and Class Switch Recombination | Q27000758 | ||
Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody | Q27644415 | ||
Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus | Q27644501 | ||
Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01 | Q27663293 | ||
Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding | Q27670829 | ||
Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2 | Q27675879 | ||
Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization | Q27677117 | ||
Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies | Q27679353 | ||
Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G | Q27704710 | ||
H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination | Q28743596 | ||
Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein | Q29306052 | ||
Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand | Q29547531 | ||
FLASH: fast length adjustment of short reads to improve genome assemblies | Q29615113 | ||
Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies | Q29619015 | ||
Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data | Q30706182 | ||
Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates | Q33612459 | ||
Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies | Q33614365 | ||
Gene-Specific Substitution Profiles Describe the Types and Frequencies of Amino Acid Changes during Antibody Somatic Hypermutation | Q33654599 | ||
Stepwise intraclonal maturation of antibody affinity through somatic hypermutation | Q33664973 | ||
Optimization and validation of the TZM-bl assay for standardized assessments of neutralizing antibodies against HIV-1. | Q33693391 | ||
Early development of broadly neutralizing antibodies in HIV-1-infected infants | Q33764917 | ||
Variants from the diverse virus population identified at seroconversion of a clade A human immunodeficiency virus type 1-infected woman have distinct biological properties | Q33814773 | ||
Host controls of HIV broadly neutralizing antibody development | Q39108769 | ||
Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection | Q39278529 | ||
Sequence intrinsic somatic mutation mechanisms contribute to affinity maturation of VRC01-class HIV-1 broadly neutralizing antibodies | Q40118226 | ||
Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies. | Q40290521 | ||
Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design | Q40679052 | ||
Intraclonal generation of antibody mutants in germinal centres | Q41172275 | ||
Reconstructing a B-cell clonal lineage. I. Statistical inference of unobserved ancestors | Q41818598 | ||
Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation | Q44486460 | ||
The nucleotide-replacement spectrum under somatic hypermutation exhibits microsequence dependence that is strand-symmetric and distinct from that under germline mutation | Q44872484 | ||
Developing an HIV vaccine | Q47852386 | ||
Immunologic memory to phosphocholine keyhole limpet hemocyanin. Recurrent mutations in the lambda 1 light chain increase affinity for antigen | Q52079184 | ||
Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms. | Q55487007 | ||
Monitoring and interpreting the intrinsic features of somatic hypermutation | Q61628475 | ||
Antibodies VRC01 and 10E8 neutralize HIV-1 with high breadth and potency even with Ig-framework regions substantially reverted to germline | Q34075820 | ||
Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies | Q34114798 | ||
Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies | Q34177732 | ||
Germinal centers | Q34245271 | ||
Global panel of HIV-1 Env reference strains for standardized assessments of vaccine-elicited neutralizing antibodies | Q34392963 | ||
Immunoglobulin somatic hypermutation | Q34638632 | ||
The neutralization breadth of HIV-1 develops incrementally over four years and is associated with CD4+ T cell decline and high viral load during acute infection | Q35076717 | ||
Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern Africa | Q35140032 | ||
Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors | Q35382871 | ||
Dynamics of B cells in germinal centres | Q35446555 | ||
HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies | Q35728947 | ||
CATNAP: a tool to compile, analyze and tally neutralizing antibody panels | Q35810109 | ||
Generation of transmitted/founder HIV-1 infectious molecular clones and characterization of their replication capacity in CD4 T lymphocytes and monocyte-derived macrophages | Q35826158 | ||
Two distinct broadly neutralizing antibody specificities of different clonal lineages in a single HIV-1-infected donor: implications for vaccine design | Q35868076 | ||
Ability to develop broadly neutralizing HIV-1 antibodies is not restricted by the germline Ig gene repertoire | Q35883727 | ||
Selection Pressure on HIV-1 Envelope by Broadly Neutralizing Antibodies to the Conserved CD4-Binding Site | Q35943521 | ||
HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen | Q35969973 | ||
Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design. | Q36112751 | ||
Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots | Q36172034 | ||
Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial. | Q36290038 | ||
Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection | Q36444787 | ||
Antigenicity and immunogenicity of RV144 vaccine AIDSVAX clade E envelope immunogen is enhanced by a gp120 N-terminal deletion | Q36559838 | ||
Molecular mechanisms of antibody somatic hypermutation. | Q36747477 | ||
Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies | Q36750045 | ||
HIV-1 Neutralizing Antibodies with Limited Hypermutation from an Infant | Q37059216 | ||
Visualizing antibody affinity maturation in germinal centers | Q37078589 | ||
Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages | Q37221575 | ||
Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies | Q37246321 | ||
HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies | Q37293480 | ||
Immunologic Basis for Long HCDR3s in Broadly Neutralizing Antibodies Against HIV-1. | Q38219407 | ||
Sequence-Intrinsic Mechanisms that Target AID Mutational Outcomes on Antibody Genes | Q38388195 | ||
Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires | Q38747466 | ||
Reconstructing a B-Cell Clonal Lineage. II. Mutation, Selection, and Affinity Maturation | Q38988188 | ||
P433 | issue | 6 | |
P304 | page(s) | 759-765.e6 | |
P577 | publication date | 2018-05-31 | |
P1433 | published in | Cell Host & Microbe | Q5058153 |
P1476 | title | Functional Relevance of Improbable Antibody Mutations for HIV Broadly Neutralizing Antibody Development. | |
P478 | volume | 23 |
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