Alcohol's Effect on Host Defense

scientific article

Alcohol's Effect on Host Defense is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P932PMC publication ID4590613
P698PubMed publication ID26695755

P2093author name stringGyongyi Szabo
Banishree Saha
P2860cites workClinically relevant concentrations of ethanol attenuate primed neutrophil bactericidal activityQ74302785
Effect of chronic coadministration of endotoxin and ethanol on rat liver pathology and proinflammatory and anti-inflammatory cytokinesQ77363684
Chronic alcohol consumption is associated with changes in the distribution, immunophenotype, and the inflammatory cytokine secretion profile of circulating dendritic cellsQ80040530
Increased immunoglobulin A in alcoholic liver cirrhosis: exploring the response of B cells to Toll-like receptor 9 activationQ84527447
Activation of toll-like receptor 3 attenuates alcoholic liver injury by stimulating Kupffer cells and stellate cells to produce interleukin-10 in miceQ87396628
Ethanol affects the generation, cosignaling molecule expression, and function of plasmacytoid and myeloid dendritic cell subsets in vitro and in vivoQ46945116
TLR2- and TLR4-mediated signals determine attenuation or augmentation of inflammation by acute alcohol in monocytes.Q51807119
The differing effects of acute and chronic alcohol on gastric and intestinal permeability.Q52512723
Chronic-alcohol-abuse-induced oxidative stress in the development of acute respiratory distress syndrome.Q52633619
Role of inflammatory pathways, blood mononuclear cells, and gut-derived bacterial products in alcohol dependence.Q54368648
Acute alcohol activates STAT3, AP-1, and Sp-1 transcription factors via the family of Src kinases to promote IL-10 production in human monocytesQ57375031
Alcohol-induced vacuolization in bone marrow cells: ultrastructure and mechanism of formationQ68407618
T and B cell function in alcoholic liver diseaseQ69991179
Rapidly fatal outcome of bacteremic Klebsiella pneumoniae pneumonia in alcoholicsQ72389089
Chronic alcohol-induced microRNA-155 contributes to neuroinflammation in a TLR4-dependent manner in miceQ21559575
Enteric dysbiosis associated with a mouse model of alcoholic liver diseaseQ24594915
Anti-inflammatory and pro-inflammatory roles of TGF-beta, IL-10, and IL-22 in immunity and autoimmunityQ24642507
Pathogen recognition and inflammatory signaling in innate immune defensesQ24643034
Effect of ethanol on innate antiviral pathways and HCV replication in human liver cellsQ24813993
Alcoholic liver disease: pathogenesis, management, and novel targets for therapyQ26861620
Alcohol abuse, the alveolar macrophage and pneumoniaQ26999697
Macrophage phagocytosis: effects of environmental pollutants, alcohol, cigarette smoke, and other external factorsQ27006556
IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in miceQ27008536
Cell death-associated molecular-pattern molecules: inflammatory signaling and controlQ27014671
Alcoholic liver disease: pathogenesis and new therapeutic targetsQ27690220
Host-microbiome interactions in alcoholic liver diseaseQ27693308
Decreased pulmonary inflammation following ethanol and burn injury in mice deficient in TLR4 but not TLR2 signalingQ28387118
Unhealthy alcohol use, HIV infection and risk of liver fibrosis in drug users with hepatitis CQ28484313
High mobility group box 1/Toll-like receptor danger signaling increases brain neuroimmune activation in alcohol dependenceQ28568437
The M1 and M2 paradigm of macrophage activation: time for reassessmentQ29615845
Type I interferons in host defenseQ29615912
Macrophage activation and polarization: nomenclature and experimental guidelinesQ29620642
The association between alcohol use, alcohol use disorders and tuberculosis (TB). A systematic reviewQ30955276
Excess alcohol consumption is common in patients with cytopenia: studies in blood and bone marrow cellsQ33360529
Alcohol abuse and pulmonary diseaseQ33755478
Consequences of alcohol consumption on host defenceQ33830107
Microbiota-liver axis in hepatic disease.Q33855414
Acute alcohol intake induces SOCS1 and SOCS3 and inhibits cytokine-induced STAT1 and STAT3 signaling in human monocytesQ33977596
Inhibition of TLR8- and TLR4-induced Type I IFN induction by alcohol is different from its effects on inflammatory cytokine production in monocytesQ34036392
Enteric bacteria, lipopolysaccharides and related cytokines in inflammatory bowel disease: biological and clinical significanceQ34070792
Alcohol exposure impairs myeloid dendritic cell function in rhesus macaquesQ34167130
Both bone marrow-derived and non-bone marrow-derived cells contribute to AIM2 and NLRP3 inflammasome activation in a MyD88-dependent manner in dietary steatohepatitisQ34214279
Alcohol facilitates HCV RNA replication via up-regulation of miR-122 expression and inhibition of cyclin G1 in human hepatoma cellsQ34228009
From Monocytes to M1/M2 Macrophages: Phenotypical vs. Functional DifferentiationQ34359869
Alcoholism: a systemic proinflammatory conditionQ34405036
Intestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severityQ34409186
Treatment of alcoholic liver diseaseQ34565692
Micro-RNA-155 deficiency prevents alcohol-induced serum endotoxin increase and small bowel inflammation in miceQ34659613
Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.Q34659689
Mechanisms by which chronic ethanol feeding limits the ability of dendritic cells to stimulate T-cell proliferationQ34678846
The inflammatory response to cell deathQ34718276
Chronic alcohol consumption enhances iNKT cell maturation and activationQ34987153
Mechanisms of alcohol-mediated hepatotoxicity in human-immunodeficiency-virus-infected patientsQ35012716
Acute immunomodulatory effects of binge alcohol ingestionQ35039859
Pathogenic interactions between alcohol and hepatitis C.Q35046563
Alcohol enhances Acinetobacter baumannii-associated pneumonia and systemic dissemination by impairing neutrophil antimicrobial activity in a murine model of infectionQ35154057
T-cell-B-cell cooperationQ35730842
Recent advances in alcoholic liver disease. IV. Dysregulated cytokine metabolism in alcoholic liver diseaseQ35872557
Bacterial translocation and changes in the intestinal microbiome in mouse models of liver diseaseQ35977446
Alcohol's contribution to compromised immunity.Q36038796
Association of chronic alcohol consumption and increased susceptibility to and pathogenic effects of pulmonary infection with respiratory syncytial virus in miceQ36149016
Induction of Bcl-3 by acute binge alcohol results in toll-like receptor 4/LPS toleranceQ36188860
Cooperation between CD4+ and CD8+ T cells: when, where, and how.Q36427362
Intracellular pattern recognition receptors in the host responseQ36528528
Microbial translocation in the pathogenesis of HIV infection and AIDS.Q36558287
Acute alcohol intoxication impairs the hematopoietic precursor cell response to pneumococcal pneumoniaQ36584494
Alcohol-induced IL-1β in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammationQ36935742
Th17 cells and their associated cytokines in liver diseasesQ37067749
Toll-like receptors and adaptor molecules in liver disease: updateQ37174620
Innate immunity in alcoholic liver diseaseQ37174755
Alcohol impairs the myeloid proliferative response to bacteremia in mice by inhibiting the stem cell antigen-1/ERK pathway.Q37195600
STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease.Q37236401
Alcoholic lung injury: metabolic, biochemical and immunological aspectsQ37249939
Acute alcohol intoxication inhibits the lineage- c-kit+ Sca-1+ cell response to Escherichia coli bacteremiaQ37317699
The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytesQ37354457
Innate immunity to virus infection.Q37361448
The roles of TLRs, RLRs and NLRs in pathogen recognitionQ37402176
Signalling pathways in alcohol-induced liver inflammation.Q37461766
Alcohol abuse, immunosuppression, and pulmonary infection.Q37561225
A histologic scoring system for prognosis of patients with alcoholic hepatitisQ37710980
Alcoholic liver disease and the gut-liver axisQ37711304
The role of intestinal endotoxin in liver injury: a long and evolving historyQ37796722
T-helper 17 cell: A distinctive cell in liver diseasesQ37812400
Regulation and functions of the IL-10 family of cytokines in inflammation and diseaseQ37821924
The unfolding web of innate immune dysregulation in alcoholic liver injuryQ37834042
Gut-liver axis and sensing microbesQ37869765
Alcohol abuse and Streptococcus pneumoniae infections: consideration of virulence factors and impaired immune responsesQ37914449
Infections in alcoholic patients.Q37977422
Signaling in innate immunity and inflammationQ37980557
Bermuda Triangle for the liver: alcohol, obesity, and viral hepatitisQ38121566
The inflammasome and its regulationQ38191992
Converging actions of alcohol on liver and brain immune signalingQ38245114
Homeostatic inflammation in innate immunityQ38246229
Ethanol inhibition of signal transduction in superoxide production by rat alveolar macrophages. A proposed mechanism for ethanol related pneumoniaQ39229079
Increased susceptibility of experimental animals to infectious organisms as a consequence of ethanol consumption.Q41281982
M2 Kupffer cells promote M1 Kupffer cell apoptosis: a protective mechanism against alcoholic and nonalcoholic fatty liver diseaseQ42710363
Inhibition of antigen-presenting cell functions by alcohol: implications for hepatitis C virus infectionQ42989432
Pivotal role of TLR4 receptors in alcohol-induced neuroinflammation and brain damageQ43016846
Acute ethanol intoxication suppresses lung chemokine production following infection with Streptococcus pneumoniaeQ43765087
Reduced alloreactive T-cell activation after alcohol intake is due to impaired monocyte accessory cell function and correlates with elevated IL-10, IL-13, and decreased IFNgamma levelsQ43848022
Gut-associated lymphoid T cell suppression enhances bacterial translocation in alcohol and burn injuryQ43997173
Acute alcohol consumption inhibits accessory cell function of monocytes and dendritic cells.Q44163176
Additive inhibition of dendritic cell allostimulatory capacity by alcohol and hepatitis C is not restored by DC maturation and involves abnormal IL-10 and IL-2 inductionQ44490223
Suppression of innate immunity by acute ethanol administration: a global perspective and a new mechanism beginning with inhibition of signaling through TLR3.Q45007554
In vivo ethanol exposure down-regulates TLR2-, TLR4-, and TLR9-mediated macrophage inflammatory response by limiting p38 and ERK1/2 activationQ45195947
Independent and combined action of hepatitis C virus infection and alcohol consumption on the risk of symptomatic liver cirrhosisQ45756849
Ethanol induces TLR4/TLR2 association, triggering an inflammatory response in microglial cellsQ46334496
The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88.Q46367336
Moderate alcohol intake in humans attenuates monocyte inflammatory responses: inhibition of nuclear regulatory factor kappa B and induction of interleukin 10.Q46909253
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectethanolQ153
alcoholsQ156
immune systemQ1059
depressantQ1976211
alcohol consumptionQ2647488
alcoholismQ15326
immunocompromised hostQ64732748
hemic and immune systemsQ70202933
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)159-70
P577publication date2015-01-01
P1433published inAlcohol research : current reviewsQ26842166
P1476titleAlcohol's Effect on Host Defense
P478volume37

Reverse relations

cites work (P2860)
Q42361153A Case of Infective Endocarditis and Spinal Epidural Abscess Caused by Streptococcus mitis Bacteremia.
Q59137705Acute Epiglottitis with Concurrent Pneumonia and Septic Shock in an Alcoholic Adult Patient
Q33634052Adolescent Ethanol Exposure Leads to Stimulus-Specific Changes in Cytokine Reactivity and Hypothalamic-Pituitary-Adrenal Axis Sensitivity in Adulthood
Q47557847Alcohol Use and HIV Disease Progression in an Antiretroviral Naïve Cohort
Q41217905Alcohol consumption as a risk factor for tuberculosis: meta-analyses and burden of disease
Q42650073Alcohol drinking and cigarette smoking in relation to risk of active tuberculosis: prospective cohort study
Q58803729Alcohol enhances type 1 interferon-α production and mortality in young mice infected with Mycobacterium tuberculosis
Q38630818Alcohol use disorder increases the risk of necrotizing fasciitis: A nationwide retrospective cohort study
Q39316673Alcohol, aging, and innate immunity
Q60047414Bacterial infections among patients with psychiatric disorders: Relation with hospital stay, age, and psychiatric diagnoses
Q64104715Causes and Consequences of Innate Immune Dysfunction in Cirrhosis
Q64999497Chronic heavy drinking drives distinct transcriptional and epigenetic changes in splenic macrophages.
Q41558224Comorbid post-traumatic stress disorder in alcohol use disorder: relationships to demography, drinking and neuroimmune profile
Q37549546Cytokine Changes following Acute Ethanol Intoxication in Healthy Men: A Crossover Study
Q33914854Epigenetic Interactions between Alcohol and Cannabinergic Effects: Focus on Histone Modification and DNA Methylation
Q47298502Ethanol and Cytokines in the Central Nervous System
Q33860053Hazardous alcohol consumption is not associated with CD4+ T-cell count decline among PLHIV in Kampala Uganda: A prospective cohort study
Q64880200Impact of Binge Alcohol Intoxication on the Humoral Immune Response during Burkholderia spp. Infections.
Q60924325In silico study of principal sex hormone effects on post-injury synovial inflammatory response
Q28074737In utero alcohol effects on foetal, neonatal and childhood lung disease
Q49918391Liver Tissue Metabolically Transformed by Alcohol Induces Immune Recognition of Liver Self Proteins but not in vivo Inflammation.
Q33659011Mystic Acetaldehyde: The Never-Ending Story on Alcoholism
Q41320670Novel detection of post-translational modifications in human monocyte-derived dendritic cells after chronic alcohol exposure: Role of inflammation regulator H4K12ac
Q90200239Peripheral proinflammatory markers are upregulated in abstinent alcohol-dependent patients but are not affected by cognitive bias modification: Preliminary findings
Q91843281Persistence of Burkholderia thailandensis E264 in lung tissue after a single binge alcohol episode
Q89622742Pulmonary artery aneurysm rupture
Q89965589Short-Chain Alcohols Upregulate GILZ Gene Expression and Attenuate LPS-Induced Septic Immune Response
Q64229047Sporotrichosis In Immunocompromised Hosts
Q99553767Substance use and related harms in the context of COVID-19: Aa conceptual model
Q46005086Summary of the 2016 Alcohol and Immunology Research Interest Group (AIRIG) meeting.
Q89879900The Effects of Ethanol on the Heart: Alcoholic Cardiomyopathy
Q33757810The effect of alcohol on the differential expression of cluster of differentiation 14 gene, associated pathways, and genetic network
Q39154504The link between inflammation, bugs, the intestine and the brain in alcohol dependence
Q33698181The relationship between different dimensions of alcohol use and the burden of disease-an update
Q64946866The sesquiterpene beta-caryophyllene oxide attenuates ethanol drinking and place conditioning in mice.
Q90557777Time Course of Blood and Brain Cytokine/Chemokine Levels Following Adolescent Alcohol Exposure and Withdrawal in Rats
Q90559418Time course of microglia activation and brain and blood cytokine/chemokine levels following chronic ethanol exposure and protracted withdrawal in rats
Q47381286Voluntary exposure to a toxin: the genetic influence on ethanol consumption.

Search more.