Small-Molecule Inhibitors of the Type III Secretion System

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Small-Molecule Inhibitors of the Type III Secretion System is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3390/MOLECULES200917659
P932PMC publication ID6332019
P698PubMed publication ID26404233
P5875ResearchGate publication ID282175698

P2093author name stringXin Chen
Shanshan Zhou
Lanping Zhu
Lingling Gu
Cuirong Liang
P2860cites workTopology and organization of the Salmonella typhimurium type III secretion needle complex componentsQ21131560
Structural insights into the assembly of the type III secretion needle complex.Q24547949
Atomic model of the type III secretion system needleQ24604172
Identification and characterization of a novel type III secretion system in trh-positive Vibrio parahaemolyticus strain TH3996 reveal genetic lineage and diversity of pathogenic machinery beyond the species levelQ24644486
A conserved structural motif mediates formation of the periplasmic rings in the type III secretion systemQ27655277
Three-dimensional model of Salmonella's needle complex at subnanometer resolutionQ27666889
Biological weapons--a primer for microbiologistsQ28215581
Chaperone release and unfolding of substrates in type III secretionQ28275782
Protein delivery into eukaryotic cells by type III secretion machinesQ28276443
Targeting bacterial virulence: inhibitors of type III secretion in YersiniaQ31137077
Small molecules aimed at type III secretion systems to inhibit bacterial virulenceQ41974659
Tethered thiazolidinone dimers as inhibitors of the bacterial type III secretion system.Q42148231
Substituted 2-imino-5-arylidenethiazolidin-4-one inhibitors of bacterial type III secretion.Q43177321
Guadinomines, Type III secretion system inhibitors, produced by Streptomyces sp. K01-0509. II: physico-chemical properties and structure elucidationQ46575462
Structure of an OhrR-ohrA operator complex reveals the DNA binding mechanism of the MarR familyQ46739652
Type III secretion: what's in a name?Q48704278
Assembly of the inner rod determines needle length in the type III secretion injectisomeQ50080247
Derivative of plant phenolic compound inhibits the type III secretion system of Dickeya dadantii via HrpX/HrpY two-component signal transduction and Rsm systems.Q54286218
A small-molecule inhibitor of the bacterial type III secretion system protects against in vivo infection with Citrobacter rodentium.Q54374354
Caminoside A, an antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconiaQ78492240
Caminosides B-D, antimicrobial glycolipids isolated from the marine sponge Caminus sphaeroconiaQ82653366
Fire Blight Management in the Twenty-first Century: Using New Technologies that Enhance Host Resistance in AppleQ91974492
Transcriptional inhibitor of virulence factors in enteropathogenic Escherichia coli.Q33224085
An inhibitor of gram-negative bacterial virulence protein secretionQ33375894
Discovery and characterization of inhibitors of Pseudomonas aeruginosa type III secretionQ33533545
Small Molecule Inhibitors of LcrF, a Yersinia pseudotuberculosis Transcription Factor, Attenuate Virulence and Limit Infection in a Murine Pneumonia ModelQ33686625
Small-molecule inhibitors specifically targeting type III secretionQ33768953
Anti-PcrV antibody in cystic fibrosis: a novel approach targeting Pseudomonas aeruginosa airway infectionQ33836925
Derivatives of plant phenolic compound affect the type III secretion system of Pseudomonas aeruginosa via a GacS-GacA two-component signal transduction systemQ34039055
Salmonella interactions with host cells: type III secretion at workQ34425135
Guadinomines, Type III secretion system inhibitors, produced by Streptomyces sp. K01-0509. I: taxonomy, fermentation, isolation and biological propertiesQ34592395
Antibiotic use in plant agricultureQ34766474
Discovery of plant phenolic compounds that act as type III secretion system inhibitors or inducers of the fire blight pathogen, Erwinia amylovora.Q34774479
A small-molecule inhibitor of type III secretion inhibits different stages of the infectious cycle of Chlamydia trachomatisQ35029284
Requirement of the Yersinia pseudotuberculosis effectors YopH and YopE in colonization and persistence in intestinal and lymph tissuesQ35165118
Functions and effectors of the Salmonella pathogenicity island 2 type III secretion systemQ35178637
Temperature sensing in Yersinia pestis: regulation of yopE transcription by lcrFQ36113530
The bacterial injection kit: type III secretion systemsQ36194906
The biology and future prospects of antivirulence therapiesQ36397902
Yersinia-induced apoptosis in vivo aids in the establishment of a systemic infection of miceQ36401192
Regulation of virulence by members of the MarR/SlyA familyQ36418301
New structural insights into the bacterial type III secretion systemQ36421215
Regulation of the type III secretion system in phytopathogenic bacteria.Q36638321
Type III secretion systems and diseaseQ36969851
Structure and biophysics of type III secretion in bacteriaQ37014297
The plant phenolic compound p-coumaric acid represses gene expression in the Dickeya dadantii type III secretion system.Q37110443
Antivirulence as a new antibacterial approach for chemotherapyQ37221247
N-hydroxybenzimidazole inhibitors of the transcription factor LcrF in Yersinia: novel antivirulence agentsQ37423363
Relative contributions of Pseudomonas aeruginosa ExoU, ExoS, and ExoT to virulence in the lungQ37624028
Anti-virulence strategies to combat bacteria-mediated diseaseQ37676924
The type III secretion injectisome, a complex nanomachine for intracellular 'toxin' deliveryQ37756149
Virulence blockers as alternatives to antibiotics: type III secretion inhibitors against Gram-negative bacteriaQ37857710
Inhibition of type III secretion in Salmonella enterica serovar Typhimurium by small-molecule inhibitorsQ37859785
Biogenesis, regulation, and targeting of the type III secretion systemQ37874812
Enteropathogenic Escherichia coli infection induces expression of the early growth response factor by activating mitogen-activated protein kinase cascades in epithelial cells.Q39522387
Supramolecular structure of the Shigella type III secretion machinery: the needle part is changeable in length and essential for delivery of effectorsQ40392389
The Yersinia Yop virulon: a bacterial system for subverting eukaryotic cellsQ41390851
SycE allows secretion of YopE-DHFR hybrids by the Yersinia enterocolitica type III Ysc system.Q41470047
Modulation of virulence factor expression by pathogen target cell contactQ41490662
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectantibioticQ12187
macromolecular substanceQ75174158
P304page(s)17659-17674
P577publication date2015-09-23
P1433published inMoleculesQ151332
P1476titleSmall-Molecule Inhibitors of the Type III Secretion System
P478volume20

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cites work (P2860)
Q41006822A dynamic and adaptive network of cytosolic interactions governs protein export by the T3SS injectisome
Q26751034Bacterial Control of Pores Induced by the Type III Secretion System: Mind the Gap
Q40116893Characterization of Small-Molecule Scaffolds That Bind to the Shigella Type III Secretion System Protein IpaD.
Q89602486Exploring resveratrol dimers as virulence blocking agents - Attenuation of type III secretion in Yersinia pseudotuberculosis and Pseudomonas aeruginosa
Q60949639High-Throughput Screening for Bacterial Glycosyltransferase Inhibitors
Q40298917In Situ Molecular Architecture of the Salmonella Type III Secretion Machine
Q88011724Protein-Injection Machines in Bacteria
Q57114106Small Molecule Inhibitor of Type Three Secretion System Belonging to a Class 2,4-disubstituted-4H-[1,3,4]-thiadiazine-5-ones Improves Survival and Decreases Bacterial Loads in an Airway Infection in Mice
Q92557925Tanshinones: First-in-Class Inhibitors of the Biogenesis of the Type 3 Secretion System Needle of Pseudomonas aeruginosa for Antibiotic Therapy
Q55002237The Herbal Compound Thymol Protects Mice From Lethal Infection by Salmonella Typhimurium.
Q40182759The salicylidene acylhydrazide INP0341 attenuates Pseudomonas aeruginosa virulence in vitro and in vivo
Q48114171Visualization and characterization of individual type III protein secretion machines in live bacteria

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