Visualization and characterization of individual type III protein secretion machines in live bacteria

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Visualization and characterization of individual type III protein secretion machines in live bacteria is …
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scholarly articleQ13442814

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P356DOI10.1073/PNAS.1705823114
P932PMC publication ID5468683
P698PubMed publication ID28533372

P50authorYongdeng ZhangQ57334346
Joerg BewersdorfQ49516549
P2093author name stringJorge E Galán
María Lara-Tejero
P2860cites workThe 2015 super-resolution microscopy roadmapQ56806459
SnapShot: effector proteins of type III secretion systemsQ80615192
Topology and organization of the Salmonella typhimurium type III secretion needle complex componentsQ21131560
Structural insights into the assembly of the type III secretion needle complex.Q24547949
Three-dimensional super-resolution imaging by stochastic optical reconstruction microscopyQ24642820
Small-Molecule Inhibitors of the Type III Secretion SystemQ26781403
Spatial and numerical regulation of flagellar biosynthesis in polarly flagellated bacteriaQ26853004
Assembly and structure of the T3SSQ26865556
Bacterial type III secretion systems: specialized nanomachines for protein delivery into target cellsQ27028058
Composition, formation, and regulation of the cytosolic c-ring, a dynamic component of the type III secretion injectisomeQ27313367
Structural Features Reminiscent of ATP-Driven Protein Translocases Are Essential for the Function of a Type III Secretion-Associated ATPaseQ27322401
Structure of a bacterial type III secretion system in contact with a host membrane in situQ27340227
Common architecture of the flagellar type III protein export apparatus and F- and V-type ATPasesQ27666617
Three-dimensional model of Salmonella's needle complex at subnanometer resolutionQ27666889
In situ structural analysis of the Yersinia enterocolitica injectisomeQ27679340
Real-time imaging of type III secretion: Salmonella SipA injection into host cellsQ30476101
Deciphering the assembly of the Yersinia type III secretion injectisomeQ30494891
Video-rate nanoscopy using sCMOS camera-specific single-molecule localization algorithmsQ30540988
Molecular organization of cytokinesis nodes and contractile rings by super-resolution fluorescence microscopy of live fission yeastQ30819726
A Salmonella inositol polyphosphatase acts in conjunction with other bacterial effectors to promote host cell actin cytoskeleton rearrangements and bacterial internalizationQ31795453
Three-dimensional sub-100 nm resolution fluorescence microscopy of thick samplesQ33333439
Three-dimensional, single-molecule fluorescence imaging beyond the diffraction limit by using a double-helix point spread functionQ33408484
The type III secretion system tip complex and translocon.Q34011259
Bacterial nanomachines: the flagellum and type III injectisome.Q34142106
Organization and coordinated assembly of the type III secretion export apparatusQ34200197
Rational design of true monomeric and bright photoactivatable fluorescent proteinsQ34274562
Biogenesis, architecture, and function of bacterial type IV secretion systemsQ34449723
Supramolecular structure of the Salmonella typhimurium type III protein secretion systemQ34746894
Visualization of the type III secretion sorting platform of Shigella flexneriQ35037858
Accounting for limited detection efficiency and localization precision in cluster analysis in single molecule localization microscopyQ35582760
Homologs of the Shigella IpaB and IpaC invasins are required for Salmonella typhimurium entry into cultured epithelial cellsQ35589961
A common assembly module in injectisome and flagellar type III secretion sorting platformsQ35646384
Antibacterial Flavonoids from Medicinal Plants Covalently Inactivate Type III Protein Secretion SubstratesQ36797957
Expression of Salmonella typhimurium genes required for invasion is regulated by changes in DNA supercoilingQ36984314
Structure and biophysics of type III secretion in bacteriaQ37014297
Ultra-High Resolution 3D Imaging of Whole Cells.Q37218547
Common themes in the design and function of bacterial effectorsQ37312444
Structural dissection of the extracellular moieties of the type III secretion apparatusQ37460910
Splitsville: structural and functional insights into the dynamic bacterial Z ringQ37623180
The type III secretion injectisome, a complex nanomachine for intracellular 'toxin' deliveryQ37756149
The blueprint of the type-3 injectisomeQ37993038
Superresolution microscopy for microbiologyQ38040513
Fluorescence imaging for bacterial cell biology: from localization to dynamics, from ensembles to single moleculesQ38227100
Unveiling the inner workings of live bacteria using super-resolution microscopy.Q38266146
Approaches targeting the type III secretion system to treat or prevent bacterial infectionsQ38366322
Secretion systems in Gram-negative bacteria: structural and mechanistic insights.Q38482854
Congenital Heart Disease Genetics Uncovers Context-Dependent Organization and Function of Nucleoporins at CiliaQ39424289
In Situ Molecular Architecture of the Salmonella Type III Secretion MachineQ40298917
Determination of the Stoichiometry of the Complete Bacterial Type III Secretion Needle Complex Using a Combined Quantitative Proteomic ApproachQ40782943
A sorting platform determines the order of protein secretion in bacterial type III systemsQ41876550
Common and distinct structural features of Salmonella injectisome and flagellar basal bodyQ42450071
Single-molecule evaluation of fluorescent protein photoactivation efficiency using an in vivo nanotemplate.Q48611227
Assembly of the inner rod determines needle length in the type III secretion injectisomeQ50080247
The invasion-associated type III system of Salmonella typhimurium directs the translocation of Sip proteins into the host cellQ50134497
P433issue23
P407language of work or nameEnglishQ1860
P921main subjectvisualizationQ451553
P304page(s)6098-6103
P577publication date2017-05-22
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleVisualization and characterization of individual type III protein secretion machines in live bacteria
P478volume114

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cites work (P2860)
Q58792122Bacterial type III secretion systems: a complex device for the delivery of bacterial effector proteins into eukaryotic host cells
Q47224322Biological Insight from Super-Resolution Microscopy: What We Can Learn from Localization-Based Images.
Q61797990Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry
Q92915177Dominant negative effects by inactive Spa47 mutants inhibit T3SS function and Shigella virulence
Q93382220Escherichia coli "Marionette" strains with 12 highly optimized small-molecule sensors
Q92732964From single bacterial cell imaging towards in vivo single-molecule biochemistry studies
Q55411495High-Throughput Screening of Type III Secretion Determinants Reveals a Major Chaperone-Independent Pathway.
Q111442045Implementation of a 4Pi-SMS super-resolution microscope
Q88011724Protein-Injection Machines in Bacteria
Q58701251Revealing the mechanisms of membrane protein export by virulence-associated bacterial secretion systems
Q64230215Role of SpaO in the assembly of the sorting platform of a Salmonella type III secretion system
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Q92498892Structural analysis of ligand-bound states of the Salmonella type III secretion system ATPase InvC
Q100506990Super-resolution Microscopy with Single Molecules in Biology and Beyond-Essentials, Current Trends, and Future Challenges
Q64075941The Injectisome, a Complex Nanomachine for Protein Injection into Mammalian Cells
Q47583224Tracking elusive cargo: Illuminating spatio-temporal Type 3 effector protein dynamics using reporters.
Q60934153Visualization of translocons in Yersinia type III protein secretion machines during host cell infection
Q57166584Visualizing and discovering cellular structures with super-resolution microscopy

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