Functional significance of macrophages in pancreatic cancer biology

scientific article

Functional significance of macrophages in pancreatic cancer biology is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1046494511
P356DOI10.1007/S13277-015-4127-2
P932PMC publication ID4689759
P698PubMed publication ID26411672
P5875ResearchGate publication ID282350459

P2093author name stringTing Han
Hai Hu
Li-Wei Wang
Feng Jiao
P2860cites workExploring the full spectrum of macrophage activationQ24653754
The pancreatic stellate cell: a star on the rise in pancreatic diseasesQ24676727
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Remodelling the extracellular matrix in development and diseaseQ26864798
A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growthQ27345215
Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapyQ27690653
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Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancerQ27860681
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Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesisQ28140740
Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancerQ28274188
Cancer stem cells in solid tumours: accumulating evidence and unresolved questionsQ28293535
Stage-associated overexpression of the ubiquitin-like protein, ISG15, in bladder cancerQ28384157
A PK2/Bv8/PROK2 antagonist suppresses tumorigenic processes by inhibiting angiogenesis in glioma and blocking myeloid cell infiltration in pancreatic cancerQ28485246
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Genetic Deficiency in Plasma Protein HRG Enhances Tumor Growth and Metastasis by Exacerbating Immune Escape and Vessel AbnormalizationQ56999677
Stromal SPARC expression and patient survival after chemoradiation for non-resectable pancreatic adenocarcinomaQ60609872
Peritumoral fibroblast SPARC expression and patient outcome with resectable pancreatic adenocarcinomaQ79600998
Cancer stem cellsQ80312237
Significance of M2-polarized tumor-associated macrophage in pancreatic cancerQ84573386
Impact of tumor-associated macrophages on invasive ductal carcinoma of the pancreas headQ84893126
Macrophage derived chemokine (CCL22), thymus and activation-regulated chemokine (CCL17), and CCR4 in idiopathic pulmonary fibrosisQ37341261
An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis.Q37486791
Stromal biology and therapy in pancreatic cancer.Q37802090
Adjuvant treatment of pancreatic cancerQ37937922
Molecular link mechanisms between inflammation and cancerQ38013290
The role of stroma in pancreatic cancer: diagnostic and therapeutic implicationsQ38019761
Macrophages and angiogenesis: a role for Wnt signalingQ38039501
Origin and turnover of monocytes and macrophagesQ38600410
Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products.Q40144497
Macrophages and angiogenesisQ40386885
A better understanding of anti-inflammatory drugs based on isoforms of cyclooxygenase (COX-1 and COX-2).Q40400101
Desmoplastic reaction in pancreatic cancer: role of pancreatic stellate cellsQ40515728
Expression of transforming growth factor-beta 1 by pancreatic stellate cells and its implications for matrix secretion and turnover in chronic pancreatitisQ42151300
Inhibition of CXCLs/CXCR2 axis in the tumor microenvironment might be a potent therapeutics for pancreatic cancerQ42214252
Lipopolysaccharide-activated macrophages stimulate the synthesis of collagen type I and C-fibronectin in cultured pancreatic stellate cellsQ42795032
Celecoxib inhibits vascular endothelial growth factor expression in and reduces angiogenesis and metastasis of human pancreatic cancer via suppression of Sp1 transcription factor activityQ44802879
Delayed chemokine receptor 1 blockade prolongs survival in collagen 4A3-deficient mice with Alport disease.Q45269853
Impeding macrophage entry into hypoxic tumor areas by Sema3A/Nrp1 signaling blockade inhibits angiogenesis and restores antitumor immunity.Q46373208
Inhibition of bone and muscle metastases of lung cancer cells by a decrease in the number of monocytes/macrophagesQ46405799
The activated stroma index is a novel and independent prognostic marker in pancreatic ductal adenocarcinomaQ46474773
Connective tissue growth factor (CCN2) in rat pancreatic stellate cell function: integrin alpha5beta1 as a novel CCN2 receptorQ46687832
SHIP represses the generation of alternatively activated macrophagesQ46754459
Phase II trial of bevacizumab plus gemcitabine in patients with advanced pancreatic cancerQ46781781
Cyclooxygenase-2 is required for activated pancreatic stellate cells to respond to proinflammatory cytokinesQ28569402
Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and MetastasisQ29396371
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancerQ29547558
Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trialQ29547565
New functions for the matrix metalloproteinases in cancer progressionQ29547738
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Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancerQ29614302
Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigmQ29614349
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancerQ29614599
Targeting hypoxia in cancer therapyQ29615491
Tumorigenesis and the angiogenic switchQ29619849
Cationic amino acid transporter-2 regulates immunity by modulating arginase activityQ33325920
MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesisQ33744153
Tumor associated macrophage × cancer cell hybrids may acquire cancer stem cell properties in breast cancerQ34359276
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.Q34429912
ISG15 is a critical microenvironmental factor for pancreatic cancer stem cellsQ34446154
Anti-inflammatory properties of the novel antitumor agent yondelis (trabectedin): inhibition of macrophage differentiation and cytokine productionQ34556431
Macrophages regulate the angiogenic switch in a mouse model of breast cancerQ34582812
Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.Q34659689
Targeting tumor-associated macrophages as a novel strategy against breast cancerQ34803221
Receptor tyrosine kinases and TLR/IL1Rs unexpectedly activate myeloid cell PI3kγ, a single convergent point promoting tumor inflammation and progression.Q35129307
Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cellsQ35134007
Cell migration: a novel aspect of pancreatic stellate cell biologyQ35595634
Combined blockade of integrin-α4β1 plus cytokines SDF-1α or IL-1β potently inhibits tumor inflammation and growthQ35645125
Differential macrophage programming in the tumor microenvironmentQ35803027
Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues.Q35825254
In situ quantitation of inflammatory mononuclear cells in ductal infiltrating breast carcinoma. Relation to prognostic parametersQ35856477
Regulation of the chemokine receptor CXCR4 by hypoxiaQ36371842
Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responsesQ36586333
Ubiquitin and ubiquitin-like proteins in cancer pathogenesisQ36601000
Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approachQ36612202
Inflammatory monocyte mobilization decreases patient survival in pancreatic cancer: a role for targeting the CCL2/CCR2 axisQ36980064
Macrophages and chemokines as mediators of angiogenesisQ36983319
Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasiaQ37040899
A starring role for stellate cells in the pancreatic cancer microenvironmentQ37059888
Pancreatic cancer stem cells.Q37186408
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectcellQ7868
macrophageQ184204
adenocarcinomaQ356033
pancreatic ductal carcinomaQ8263002
hemic and immune systemsQ70202933
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)9119-26
P577publication date2015-12-01
P1433published inTumor BiologyQ15757842
P1476titleFunctional significance of macrophages in pancreatic cancer biology
P478volume36

Reverse relations

cites work (P2860)
Q99417952IL-20 antagonist suppresses PD-L1 expression and prolongs survival in pancreatic cancer models
Q61810548Inflammation and pancreatic cancer: An updated review
Q47155954NF-κB regulates GDF-15 to suppress macrophage surveillance during early tumor development.
Q37624480Pancreatic stellate cell: Pandora's box for pancreatic disease biology
Q58760423p21-activated kinase signalling in pancreatic cancer: New insights into tumour biology and immune modulation

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